{"id":"https://openalex.org/W7208711527","doi":"https://doi.org/10.26480/mijhm.02.2024.12.34","title":"ADVANCEMENTS IN NATURAL POLYSACCHARIDES FOR REGULATING INTESTINAL FLORA TO IMPROVE TYPE 2 DIABETES MELLITUS","display_name":"ADVANCEMENTS IN NATURAL POLYSACCHARIDES FOR REGULATING INTESTINAL FLORA TO IMPROVE TYPE 2 DIABETES MELLITUS","publication_year":2024,"publication_date":"2024-12-28","ids":{"openalex":"https://openalex.org/W7208711527","doi":"https://doi.org/10.26480/mijhm.02.2024.12.34"},"language":"en","primary_location":{"id":"doi:10.26480/mijhm.02.2024.12.34","doi":"https://doi.org/10.26480/mijhm.02.2024.12.34","is_oa":true,"landing_page_url":"https://doi.org/10.26480/mijhm.02.2024.12.34","pdf_url":null,"source":{"id":"https://openalex.org/S7407064575","display_name":"MAHSA International Journal of Health and Medicine","issn_l":"2805-5705","issn":["2805-5705"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321761","host_organization_name":"Zibeline International Publishing","host_organization_lineage":["https://openalex.org/P4310321761"],"host_organization_lineage_names":["Zibeline International Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MAHSA International Journal of Health and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.26480/mijhm.02.2024.12.34","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5149980653","display_name":"Rong Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097525","display_name":"Youjiang Medical College for Nationalities","ror":"https://ror.org/00wemg618","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097525"]},{"id":"https://openalex.org/I4210102358","display_name":"Mahsa University","ror":"https://ror.org/00p43ne90","country_code":"MY","type":"education","lineage":["https://openalex.org/I4210102358"]}],"countries":["CN","MY"],"is_corresponding":false,"raw_author_name":"Rong Li","raw_affiliation_strings":["School of Pharmacy, Youjiang Medical University for Nationalities, Baise, 533000, Guangxi, China/Faculty of Pharmacy and Biomedical Sciences, MAHSA University, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Youjiang Medical University for Nationalities, Baise, 533000, Guangxi, China/Faculty of Pharmacy and Biomedical Sciences, MAHSA University, Selangor, Malaysia","institution_ids":["https://openalex.org/I4210097525","https://openalex.org/I4210102358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076259015","display_name":"W. Y. Chew","orcid":"https://orcid.org/0000-0002-6341-0619","observed_orcids":["https://orcid.org/0000-0002-6341-0619"]},"institutions":[{"id":"https://openalex.org/I4210102358","display_name":"Mahsa University","ror":"https://ror.org/00p43ne90","country_code":"MY","type":"education","lineage":["https://openalex.org/I4210102358"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Weiyun Chew","raw_affiliation_strings":["Centre for Pre-University Studies, MAHSA University, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Pre-University Studies, MAHSA University, Selangor, Malaysia","institution_ids":["https://openalex.org/I4210102358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077820858","display_name":"Muhammad Fattah Fazel","orcid":"https://orcid.org/0000-0003-0479-9289","observed_orcids":["https://orcid.org/0000-0003-0479-9289"]},"institutions":[{"id":"https://openalex.org/I4210102358","display_name":"Mahsa University","ror":"https://ror.org/00p43ne90","country_code":"MY","type":"education","lineage":["https://openalex.org/I4210102358"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Muhammad Fattah Fazel","raw_affiliation_strings":["Faculty of Pharmacy and Biomedical Sciences, MAHSA University, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy and Biomedical Sciences, MAHSA University, Selangor, Malaysia","institution_ids":["https://openalex.org/I4210102358"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010520057","display_name":"Venkata Sathya Saiappala Raju Velaga","orcid":"https://orcid.org/0009-0004-2148-972X","observed_orcids":["https://orcid.org/0009-0004-2148-972X"]},"institutions":[{"id":"https://openalex.org/I4210102358","display_name":"Mahsa University","ror":"https://ror.org/00p43ne90","country_code":"MY","type":"education","lineage":["https://openalex.org/I4210102358"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Venkata Sathya Saiappala","raw_affiliation_strings":["Faculty of Pharmacy and Biomedical Sciences, MAHSA University, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy and Biomedical Sciences, MAHSA University, Selangor, Malaysia","institution_ids":["https://openalex.org/I4210102358"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"04","issue":"02","first_page":"12","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9365000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9365000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12489","display_name":"Microbial Metabolites in Food Biotechnology","score":0.02319999970495701,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.016499999910593033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-polysaccharides","display_name":"natural polysaccharides","score":0.9950000047683716},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9760000109672546},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7860000133514404},{"id":"https://openalex.org/keywords/gut-dysbiosis","display_name":"gut dysbiosis","score":0.8960000276565552},{"id":"https://openalex.org/keywords/probiotic-bacteria","display_name":"probiotic bacteria","score":0.5509999990463257},{"id":"https://openalex.org/keywords/pathogenic-bacteria-inhibition","display_name":"pathogenic bacteria inhibition","score":0.8140000104904175},{"id":"https://openalex.org/keywords/microbiota-diversity","display_name":"microbiome diversity","score":0.5109999775886536},{"id":"https://openalex.org/keywords/diabetes-treatment","display_name":"diabetes treatment","score":0.6480000019073486}],"concepts":[{"id":"https://openalex.org/C2777234453","wikidata":"https://www.wikidata.org/wiki/Q2033092","display_name":"Flora (microbiology)","level":3,"score":0.8669000267982483},{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.7574999928474426},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5685999989509583},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.558899998664856},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.545199990272522},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4950999915599823},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.4846000075340271},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3903000056743622},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.37540000677108765},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36079999804496765},{"id":"https://openalex.org/C2778883795","wikidata":"https://www.wikidata.org/wiki/Q804517","display_name":"Pathogenic bacteria","level":3,"score":0.3343000113964081},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.3010999858379364},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3000999987125397},{"id":"https://openalex.org/C120667501","wikidata":"https://www.wikidata.org/wiki/Q6839493","display_name":"Microecology","level":2,"score":0.28119999170303345},{"id":"https://openalex.org/C2992093752","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Intestinal bacteria","level":3,"score":0.2809000015258789},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.267300009727478},{"id":"https://openalex.org/C2994085863","wikidata":"https://www.wikidata.org/wiki/Q1385446","display_name":"Extracellular polysaccharide","level":3,"score":0.2533999979496002}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.26480/mijhm.02.2024.12.34","doi":"https://doi.org/10.26480/mijhm.02.2024.12.34","is_oa":true,"landing_page_url":"https://doi.org/10.26480/mijhm.02.2024.12.34","pdf_url":null,"source":{"id":"https://openalex.org/S7407064575","display_name":"MAHSA International Journal of Health and Medicine","issn_l":"2805-5705","issn":["2805-5705"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321761","host_organization_name":"Zibeline International Publishing","host_organization_lineage":["https://openalex.org/P4310321761"],"host_organization_lineage_names":["Zibeline International Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MAHSA International Journal of Health and Medicine","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.26480/mijhm.02.2024.12.34","doi":"https://doi.org/10.26480/mijhm.02.2024.12.34","is_oa":true,"landing_page_url":"https://doi.org/10.26480/mijhm.02.2024.12.34","pdf_url":null,"source":{"id":"https://openalex.org/S7407064575","display_name":"MAHSA International Journal of Health and Medicine","issn_l":"2805-5705","issn":["2805-5705"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321761","host_organization_name":"Zibeline International Publishing","host_organization_lineage":["https://openalex.org/P4310321761"],"host_organization_lineage_names":["Zibeline International Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MAHSA International Journal of Health and Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3135900885","https://openalex.org/W4402535811","https://openalex.org/W4413949921","https://openalex.org/W3119707880","https://openalex.org/W4402184063","https://openalex.org/W4400036963","https://openalex.org/W4280537130","https://openalex.org/W7162781779","https://openalex.org/W4417491359","https://openalex.org/W4303188534"],"abstract_inverted_index":{"Natural":[0,61],"polysaccharides":[1,62,99,125],"can":[2,23,63],"promote":[3],"the":[4,10,58,70,97,111,119,127,135,143],"proliferation":[5],"of":[6,57,82,123,130,138,145],"beneficial":[7],"bacteria":[8,15],"in":[9,91,107],"intestinal":[11,19,33,59,71,86,105,114,128],"tract,":[12],"inhibit":[13],"pathogenic":[14],"growth,":[16],"and":[17,47,50,65,76,80,116,118,121,142],"maintain":[18],"flora":[20,34,87,106,115],"diversity.":[21],"They":[22],"also":[24],"improve":[25,101],"diseases":[26],"caused":[27],"by":[28,31,68,84,103],"microbiota":[29],"dysbiosis":[30,56],"regulating":[32,85,104],"composition.":[35],"Type":[36],"2":[37],"diabetes":[38,67,92],"mellitus":[39],"(T2DM)":[40],"is":[41],"a":[42],"typical":[43],"chronic":[44],"metabolic":[45,77],"disease,":[46],"its":[48],"onset":[49],"progression":[51],"are":[52],"closely":[53],"associated":[54],"with":[55],"flora.":[60],"treat":[64],"alleviate":[66],"affecting":[69],"flora's":[72],"species,":[73],"quantity,":[74],"abundance,":[75],"pathway.":[78],"Treatment":[79],"intervention":[81],"T2DM":[83,102,117],"have":[88],"become":[89],"directions":[90],"treatment.":[93],"This":[94,132],"study":[95],"reviewed":[96],"natural":[98,124,139],"that":[100],"recent":[108],"years,":[109],"including":[110],"relationship":[112],"between":[113],"regulation":[120],"mechanism":[122],"on":[126],"tract":[129],"T2DM.":[131,146],"work":[133],"guides":[134],"future":[136],"utilization":[137],"polysaccharide":[140],"resources":[141],"management":[144]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-09-05T00:00:00"}