{"id":"https://openalex.org/W7208047419","doi":null,"title":"Five Cases of Palliative Whole-liver Irradiation in a Single Fraction for Multiple Liver Metastases","display_name":"Five Cases of Palliative Whole-liver Irradiation in a Single Fraction for Multiple Liver Metastases","publication_year":2026,"publication_date":"2026-06-10","ids":{"openalex":"https://openalex.org/W7208047419"},"language":"ja","primary_location":{"id":"pmh:oai:irdb.nii.ac.jp:00990:0007425293","doi":null,"is_oa":true,"landing_page_url":"https://soar-ir.repo.nii.ac.jp/records/2003816","pdf_url":"https://soar-ir.repo.nii.ac.jp/record/2003816/files/Shinshuishi74-3_3.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u4fe1\u5dde\u533b\u5b66\u96d1\u8a8c","raw_type":"journal article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://soar-ir.repo.nii.ac.jp/record/2003816/files/Shinshuishi74-3_3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014984045","display_name":"Miyu Sugimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"\u6749\u6751, \u7f8e\u512a","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5131903000","display_name":"\u572d\u8036 \u6c38\u7530","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"\u5c0f\u5ca9\u4e95, \u6176\u4e00\u90ce","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"20419360","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"20419360","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081499697","display_name":"Keiichiro Koiwai","orcid":"https://orcid.org/0000-0002-3582-7572","observed_orcids":["https://orcid.org/0000-0002-3582-7572"]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KOIWAI, Keiichiro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069375273","display_name":"Yuuki Endo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"\u9577\u7530, \u666f\u4e5f","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5156484838","display_name":"\u963f\u88d5\u7f8e \u9152\u4e95","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u9152\u4e95, \u963f\u88d5\u7f8e","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5156378161","display_name":"Ayumi SAKAI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"SAKAI, Ayumi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5156682121","display_name":"\u512a\u9999 \u795e\u4e8b","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u795e\u4e8b, \u512a\u9999","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149583361","display_name":"Yuuka JINJI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JINJI, Yuuka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160514066","display_name":"\u512a\u5e0c \u9060\u85e4","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u9060\u85e4, \u512a\u5e0c","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160403390","display_name":"Yuuki ENDO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ENDO, Yuuki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160547649","display_name":"Yasunari FUJINAGA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u85e4\u6c38, \u5eb7\u6210","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"70334901","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"70334901","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"74","issue":"3","first_page":"169","last_page":"173"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.33149999380111694,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.33149999380111694,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12108","display_name":"Management of metastatic bone disease","score":0.2759000062942505,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.15189999341964722,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-fraction-radiotherapy","display_name":"single-fraction radiotherapy","score":0.8080000281333923},{"id":"https://openalex.org/keywords/palliative-radiotherapy","display_name":"palliative radiotherapy","score":0.9490000009536743},{"id":"https://openalex.org/keywords/multiple-liver-metastases","display_name":"multiple liver metastases","score":0.9039999842643738},{"id":"https://openalex.org/keywords/gastric-neuroendocrine-carcinoma","display_name":"gastric neuroendocrine carcinoma","score":0.8690000176429749},{"id":"https://openalex.org/keywords/lung-adenocarcinoma","display_name":"lung adenocarcinoma","score":0.9919999837875366},{"id":"https://openalex.org/keywords/uterine-sarcoma","display_name":"uterine sarcoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/cutaneous-melanoma","display_name":"cutaneous melanoma","score":0.984000027179718},{"id":"https://openalex.org/keywords/abdominal-pain","display_name":"abdominal pain","score":0.8550000190734863},{"id":"https://openalex.org/keywords/three-dimensional-conformal-radiotherapy","display_name":"3D conformal radiotherapy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/child-pugh-score","display_name":"Child-Pugh score","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9598000049591064},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6348000168800354},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.590499997138977},{"id":"https://openalex.org/C2780955771","wikidata":"https://www.wikidata.org/wiki/Q183425","display_name":"Abdominal pain","level":2,"score":0.4546999931335449},{"id":"https://openalex.org/C2994186709","wikidata":"https://www.wikidata.org/wiki/Q29483","display_name":"Palliative care","level":2,"score":0.42320001125335693},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4124999940395355},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.4097000062465668},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.3682999908924103},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.36820000410079956},{"id":"https://openalex.org/C2778300832","wikidata":"https://www.wikidata.org/wiki/Q1589604","display_name":"Premedication","level":2,"score":0.32269999384880066},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.3165000081062317},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3041999936103821},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.28600001335144043},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.27489998936653137},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.26019999384880066},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.25850000977516174},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25690001249313354}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:irdb.nii.ac.jp:00990:0007425293","doi":null,"is_oa":true,"landing_page_url":"https://soar-ir.repo.nii.ac.jp/records/2003816","pdf_url":"https://soar-ir.repo.nii.ac.jp/record/2003816/files/Shinshuishi74-3_3.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u4fe1\u5dde\u533b\u5b66\u96d1\u8a8c","raw_type":"journal article"},{"id":"pmh:oai:soar-ir.repo.nii.ac.jp:02003816","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10091/0002003816","pdf_url":null,"source":{"id":"https://openalex.org/S4306402150","display_name":"SOAR (Shinshu University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137975476","host_organization_name":"Shinshu University","host_organization_lineage":["https://openalex.org/I137975476"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:00990:0007425293","doi":null,"is_oa":true,"landing_page_url":"https://soar-ir.repo.nii.ac.jp/records/2003816","pdf_url":"https://soar-ir.repo.nii.ac.jp/record/2003816/files/Shinshuishi74-3_3.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u4fe1\u5dde\u533b\u5b66\u96d1\u8a8c","raw_type":"journal article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7208047419.pdf","grobid_xml":"https://content.openalex.org/works/W7208047419.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7219184257","https://openalex.org/W4402909400","https://openalex.org/W2125221609","https://openalex.org/W2336228918","https://openalex.org/W4223596814","https://openalex.org/W2593203112","https://openalex.org/W4403761494","https://openalex.org/W3043772601","https://openalex.org/W2009020655","https://openalex.org/W2429067251"],"abstract_inverted_index":{"Purpose":[0],":":[1,17,54,192,210],"To":[2],"report":[3],"on":[4],"single-fraction":[5,25],"palliative":[6,26,194],"whole-liver":[7,27,195],"irradiation":[8,28,196],"for":[9,29],"multiple":[10,30,106],"liver":[11,31,107],"metastases":[12,32],"at":[13,33,203],"our":[14,34,204],"institution.":[15,205],"Methods":[16],"We":[18],"retrospectively":[19],"reviewed":[20],"five":[21,118,168],"patients":[22,56,91,101,142,179],"who":[23,180],"underwent":[24],"hospital":[35],"between":[36],"August":[37],"2023":[38],"and":[39,48,80,95,109,170],"September":[40],"2024.":[41],"Patient":[42],"characteristics,":[43],"radiotherapy":[44,126],"details,":[45],"treatment":[46],"efficacy,":[47],"adverse":[49,187],"events":[50,188],"were":[51,92,97,189],"evaluated.":[52],"Results":[53],"The":[55,149],"ranged":[57,152],"in":[58,114,127,137,164,174],"age":[59],"from":[60,153],"28":[61],"to":[62,86,105,145,155],"76":[63],"years":[64],"(median,":[65,158],"58).":[66],"Primary":[67],"malignancies":[68],"included":[69],"gastric":[70],"neuroendocrine":[71],"carcinoma":[72],"(n\uff1d2),":[73],"lung":[74],"adenocarcinoma":[75],"(n\uff1d1),":[76,79],"uterine":[77],"sarcoma":[78],"cutaneous":[81],"malignant":[82],"melanoma":[83],"(n\uff1d1).":[84],"According":[85],"the":[87,117,167,177],"Child-Pugh":[88],"classification,":[89],"three":[90,165],"class":[93,98],"A":[94],"two":[96,175],"B.":[99],"All":[100],"had":[102,182],"symptoms":[103],"attributable":[104],"metastases,":[108],"abdominal":[110,171,183],"pain":[111,172],"was":[112,121,162],"present":[113],"four":[115,178],"of":[116,134,166,176,201],"patients.":[119],"Radiotherapy":[120],"delivered":[122],"using":[123],"three-dimensional":[124],"conformal":[125],"all":[128],"cases,":[129],"with":[130],"a":[131,138,198],"prescribed":[132],"dose":[133],"8":[135],"Gy":[136],"single":[139],"fraction.":[140],"Four":[141],"received":[143],"premedication":[144],"prevent":[146],"radiation-induced":[147],"nausea.":[148],"follow-up":[150],"period":[151],"0.7":[154],"5.6":[156],"months":[157],"2.5).":[159],"Symptomatic":[160],"improvement":[161],"observed":[163],"patients,":[169],"improved":[173],"initially":[181],"pain.":[184],"No":[185],"severe":[186],"observed.":[190],"Conclusion":[191],"Single-fraction":[193],"showed":[197],"certain":[199],"degree":[200],"effectiveness":[202],"Shinshu":[206],"Med":[207],"J":[208],"74":[209],"169":[211],"\u2015173,":[212],"2026":[213]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-09-04T00:00:00"}