{"id":"https://openalex.org/W7207970740","doi":null,"title":"Efficacy of quantitative analysis for differentiating pancreatic solid lesions using contrast-enhanced endoscopic ultrasonography","display_name":"Efficacy of quantitative analysis for differentiating pancreatic solid lesions using contrast-enhanced endoscopic ultrasonography","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W7207970740"},"language":"en","primary_location":{"id":"pmh:oai:irdb.nii.ac.jp:00828:0005002128","doi":null,"is_oa":true,"landing_page_url":"https://petit.lib.yamaguchi-u.ac.jp/28663","pdf_url":"https://petit.lib.yamaguchi-u.ac.jp/28663/files/160055","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The bulletin of the Yamaguchi Medical School","raw_type":"departmental bulletin paper"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://petit.lib.yamaguchi-u.ac.jp/28663/files/160055","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5131462841","display_name":"\u771f\u5f13 \u5b89\u7530","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuda, Mayumi","raw_affiliation_strings":["Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065680920","display_name":"Seiji Kaino","orcid":"https://orcid.org/0000-0001-7351-764X","observed_orcids":["https://orcid.org/0000-0001-7351-764X"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaino, Seiji","raw_affiliation_strings":["Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081905812","display_name":"Takanori Tsuyama","orcid":"https://orcid.org/0009-0004-9526-2843","observed_orcids":["https://orcid.org/0009-0004-9526-2843"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tsuyama, Takanori","raw_affiliation_strings":["Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112076197","display_name":"Yuko Fujimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Fujimoto, Yuko","raw_affiliation_strings":["Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084841968","display_name":"Shogo Amano","orcid":"https://orcid.org/0000-0002-4487-2420","observed_orcids":["https://orcid.org/0000-0002-4487-2420"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Amano, Shogo","raw_affiliation_strings":["Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080641253","display_name":"Hirofumi Harima","orcid":"https://orcid.org/0000-0003-0406-0345","observed_orcids":["https://orcid.org/0000-0003-0406-0345"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Harima, Hirofumi","raw_affiliation_strings":["Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology , Yamaguchi University Graduate School of Medicine , 1-1-1 Minami Kogushi , Ube , Yamaguchi 755-8505 , Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110550306","display_name":"Shigeyuki Suenaga","orcid":"https://orcid.org/0000-0003-3726-5961","observed_orcids":["https://orcid.org/0000-0003-3726-5961"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Suenaga, Shigeyuki","raw_affiliation_strings":["Yamaguchi University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi University","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5131910725","display_name":"Isao Sakaida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sakaida, Isao","raw_affiliation_strings":["Yamaguchi University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi University","institution_ids":["https://openalex.org/I173915773"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I173915773"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"68","issue":"1-2","first_page":"11","last_page":"20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.8417999744415283,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.8417999744415283,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.042100001126527786,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.032600000500679016,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-ductal-adenocarcinoma","display_name":"pancreatic ductal adenocarcinoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/solid-pancreatic-lesions","display_name":"solid pancreatic lesions","score":0.8389999866485596},{"id":"https://openalex.org/keywords/contrast-enhanced-endoscopic-ultrasonography","display_name":"contrast-enhanced endoscopic ultrasonography","score":0.9739999771118164},{"id":"https://openalex.org/keywords/time-intensity-curve-analysis","display_name":"time-intensity curve analysis","score":0.8840000033378601},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.6209999918937683},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.5450000166893005},{"id":"https://openalex.org/keywords/enhancement-patterns","display_name":"contrast enhancement patterns","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7989000082015991},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.6450999975204468},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.6184999942779541},{"id":"https://openalex.org/C95986675","wikidata":"https://www.wikidata.org/wiki/Q185168","display_name":"Quantitative analysis (chemistry)","level":2,"score":0.5260999798774719},{"id":"https://openalex.org/C2992026798","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic ductal adenocarcinoma","level":4,"score":0.5037999749183655},{"id":"https://openalex.org/C2778217198","wikidata":"https://www.wikidata.org/wiki/Q556977","display_name":"Cutoff","level":2,"score":0.4909000098705292},{"id":"https://openalex.org/C93038891","wikidata":"https://www.wikidata.org/wiki/Q1061524","display_name":"Intensity (physics)","level":2,"score":0.4747999906539917},{"id":"https://openalex.org/C3020225094","wikidata":"https://www.wikidata.org/wiki/Q80091","display_name":"Area under curve","level":3,"score":0.42329999804496765},{"id":"https://openalex.org/C3020076753","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic carcinoma","level":4,"score":0.41449999809265137},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.4059000015258789},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3797000050544739},{"id":"https://openalex.org/C3017397796","wikidata":"https://www.wikidata.org/wiki/Q1340838","display_name":"Endoscopic ultrasonography","level":3,"score":0.3732999861240387},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.3625999987125397},{"id":"https://openalex.org/C3020132585","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic accuracy","level":2,"score":0.35019999742507935},{"id":"https://openalex.org/C2776737053","wikidata":"https://www.wikidata.org/wiki/Q7130407","display_name":"Pancreatic disease","level":3,"score":0.3296000063419342},{"id":"https://openalex.org/C66882249","wikidata":"https://www.wikidata.org/wiki/Q169336","display_name":"Homogeneous","level":2,"score":0.3003000020980835},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.28690001368522644},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C2778451229","wikidata":"https://www.wikidata.org/wiki/Q212809","display_name":"Endoscopy","level":2,"score":0.2770000100135803},{"id":"https://openalex.org/C529618451","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonography","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C2984588014","wikidata":"https://www.wikidata.org/wiki/Q730675","display_name":"Quantitative assessment","level":2,"score":0.2685999870300293},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.262800008058548},{"id":"https://openalex.org/C2994142346","wikidata":"https://www.wikidata.org/wiki/Q353268","display_name":"Dynamic contrast","level":3,"score":0.26269999146461487}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:irdb.nii.ac.jp:00828:0005002128","doi":null,"is_oa":true,"landing_page_url":"https://petit.lib.yamaguchi-u.ac.jp/28663","pdf_url":"https://petit.lib.yamaguchi-u.ac.jp/28663/files/160055","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The bulletin of the Yamaguchi Medical School","raw_type":"departmental bulletin paper"}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:00828:0005002128","doi":null,"is_oa":true,"landing_page_url":"https://petit.lib.yamaguchi-u.ac.jp/28663","pdf_url":"https://petit.lib.yamaguchi-u.ac.jp/28663/files/160055","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The bulletin of the Yamaguchi Medical School","raw_type":"departmental bulletin paper"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7207970740.pdf","grobid_xml":"https://content.openalex.org/works/W7207970740.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W1559780482"],"related_works":["https://openalex.org/W2792268695","https://openalex.org/W1997747049","https://openalex.org/W4229074128","https://openalex.org/W4415373959","https://openalex.org/W2370686350","https://openalex.org/W2895117887","https://openalex.org/W4318933950","https://openalex.org/W7163655779","https://openalex.org/W2046732575","https://openalex.org/W3139426939"],"abstract_inverted_index":{"Aim:":[0],"To":[1],"evaluate":[2],"the":[3,63,70,112,135,141],"efficacy":[4],"of":[5,62,69,82,156,159,163,175,178,182],"quantitative":[6],"analysis":[7,24,75,152,168,171,187],"for":[8,40,57,140],"differentiating":[9,194],"pancreatic":[10,16,41],"ductal":[11],"adenocarcinoma":[12],"(PDAC)":[13],"and":[14,50,73,87,95,105,121,161,180,197],"inflammatory":[15],"masses":[17],"(IPM)":[18],"using":[19],"time":[20],"intensity":[21,113,142],"curve":[22,139],"(TIC)":[23],"based":[25,133],"on":[26,134],"contrast-enhanced":[27],"endoscopic":[28],"ultrasonography":[29],"(CE-EUS).":[30],"Methods:":[31],"We":[32],"reviewed":[33],"89":[34],"patients":[35],"who":[36],"had":[37,153,172],"undergone":[38],"CE-EUS":[39,53,189],"solid":[42],"lesions":[43],"at":[44,119],"our":[45],"department":[46],"between":[47,195],"August":[48],"2012":[49],"January":[51],"2016.":[52],"images":[54],"were":[55,76,84,92],"recorded":[56],"2":[58],"minutes":[59],"after":[60,124,145],"injection":[61],"contrast":[64],"agent.":[65],"The":[66,79],"diagnostic":[67,191],"abilities":[68],"enhanced":[71,80,166],"patterns":[72,81],"TIC":[74,110,151,170,186],"assessed.":[77],"Results:":[78],"PDAC":[83,149,196],"mainly":[85,93],"hypovascular":[86],"heterogeneous":[88],"(66/77),":[89],"while":[90],"IPM":[91],"isovascular":[94],"homogeneous":[96],"(6/12).":[97],"In":[98,109],"PDAC,":[99],"sensitivity":[100,155,174],"was":[101,107,116],"77.9%,":[102],"specificity":[103,158],"83.3%,":[104,179],"accuracy":[106,162,181,192],"78.7%.":[108],"analysis,":[111],"reduction":[114,143],"rate":[115,144],"significantly":[117],"different":[118],"10":[120],"30":[122,146],"seconds":[123],"peak":[125],"intensity.":[126],"After":[127],"creating":[128],"a":[129,154,173],"cutoff":[130],"value":[131],"(49%)":[132],"receiver":[136],"operating":[137],"characteristic":[138],"seconds,":[147],"diagnosing":[148],"with":[150,169,188],"67.5%,":[157],"100%,":[160],"71.9%.":[164],"Combining":[165,185],"pattern":[167],"90.9%,":[176],"pecificity":[177],"89.9%.":[183],"Conclusion:":[184],"improved":[190],"when":[193],"IPM.":[198]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-04T00:00:00"}