{"id":"https://openalex.org/W7207812475","doi":"https://doi.org/10.1186/s40780-026-00620-z","title":"Suspected retention of magnesium oxide tablets during co-administration with recovery K5, a concentrated oral enteral nutrition formula, supported by in vitro disintegration testing","display_name":"Suspected retention of magnesium oxide tablets during co-administration with recovery K5, a concentrated oral enteral nutrition formula, supported by in vitro disintegration testing","publication_year":2026,"publication_date":"2026-09-03","ids":{"openalex":"https://openalex.org/W7207812475","doi":"https://doi.org/10.1186/s40780-026-00620-z"},"language":"en","primary_location":{"id":"doi:10.1186/s40780-026-00620-z","doi":"https://doi.org/10.1186/s40780-026-00620-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40780-026-00620-z","pdf_url":null,"source":{"id":"https://openalex.org/S2737624436","display_name":"Journal of Pharmaceutical Health Care and Sciences","issn_l":"2055-0294","issn":["2055-0294"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","oarl","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Health Care and Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s40780-026-00620-z","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5126550238","display_name":"Makoto Ohira","orcid":"https://orcid.org/0000-0002-6629-8837","observed_orcids":["https://orcid.org/0000-0002-6629-8837"]},"institutions":[{"id":"https://openalex.org/I79746392","display_name":"IRYO Sosei University","ror":"https://ror.org/04v5axh10","country_code":"JP","type":"education","lineage":["https://openalex.org/I79746392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Ohira","raw_affiliation_strings":["Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan","institution_ids":["https://openalex.org/I79746392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149692554","display_name":"Hirohisa Fujitsuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256130","display_name":"Fukui Memorial Hospital","ror":"https://ror.org/03t61bk55","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256130"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirohisa Fujitsuka","raw_affiliation_strings":["Department of Pharmacy, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan","institution_ids":["https://openalex.org/I4405256130"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rin Ono","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79746392","display_name":"IRYO Sosei University","ror":"https://ror.org/04v5axh10","country_code":"JP","type":"education","lineage":["https://openalex.org/I79746392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Rin Ono","raw_affiliation_strings":["Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan","institution_ids":["https://openalex.org/I79746392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149704643","display_name":"Hikari Terui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79746392","display_name":"IRYO Sosei University","ror":"https://ror.org/04v5axh10","country_code":"JP","type":"education","lineage":["https://openalex.org/I79746392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hikari Terui","raw_affiliation_strings":["Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan","institution_ids":["https://openalex.org/I79746392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149699158","display_name":"Masanori Motegi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256130","display_name":"Fukui Memorial Hospital","ror":"https://ror.org/03t61bk55","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256130"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanori Motegi","raw_affiliation_strings":["Department of Radiology, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan","institution_ids":["https://openalex.org/I4405256130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149791502","display_name":"Susumu Kurushima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256130","display_name":"Fukui Memorial Hospital","ror":"https://ror.org/03t61bk55","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256130"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Susumu Kurushima","raw_affiliation_strings":["Medical Department, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Department, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan","institution_ids":["https://openalex.org/I4405256130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060684591","display_name":"Tatsuru Ota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256130","display_name":"Fukui Memorial Hospital","ror":"https://ror.org/03t61bk55","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256130"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tatsuru Ota","raw_affiliation_strings":["Medical Department, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Department, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan","institution_ids":["https://openalex.org/I4405256130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149788278","display_name":"Toshikazu Kitagawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256130","display_name":"Fukui Memorial Hospital","ror":"https://ror.org/03t61bk55","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256130"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshikazu Kitagawa","raw_affiliation_strings":["Medical Department, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Department, Fukui Memorial Hospital, Medical Foundation Seizankai, 1040-2 Koenbo, Hasse-machi, Miura, Kanagawa, 238-0115, Japan","institution_ids":["https://openalex.org/I4405256130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132248718","display_name":"Ryosuke Shinkai","orcid":"https://orcid.org/0009-0001-9963-0939","observed_orcids":["https://orcid.org/0009-0001-9963-0939"]},"institutions":[{"id":"https://openalex.org/I79072001","display_name":"International University of Health and Welfare","ror":"https://ror.org/053d3tv41","country_code":"JP","type":"education","lineage":["https://openalex.org/I79072001"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryosuke Shinkai","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy at Narita, International University of Health and Welfare, 4-3 Kozunomori, Narita, Chiba, 286-8686, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy at Narita, International University of Health and Welfare, 4-3 Kozunomori, Narita, Chiba, 286-8686, Japan","institution_ids":["https://openalex.org/I79072001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001487564","display_name":"Takahiro Amemiya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131632401","display_name":"Teikyo Heisei University","ror":"https://ror.org/034zkkc78","country_code":"JP","type":"education","lineage":["https://openalex.org/I131632401"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahiro Amemiya","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Teikyo Heisei University, 4-21-2 Nakano, Nakano-ku, Tokyo, 164-8530, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Teikyo Heisei University, 4-21-2 Nakano, Nakano-ku, Tokyo, 164-8530, Japan","institution_ids":["https://openalex.org/I131632401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102003094","display_name":"Takashi Tomita","orcid":"https://orcid.org/0009-0005-1045-9485","observed_orcids":["https://orcid.org/0009-0005-1045-9485","https://orcid.org/0000-0001-5204-2454"]},"institutions":[{"id":"https://openalex.org/I79072001","display_name":"International University of Health and Welfare","ror":"https://ror.org/053d3tv41","country_code":"JP","type":"education","lineage":["https://openalex.org/I79072001"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takashi Tomita","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy at Narita, International University of Health and Welfare, 4-3 Kozunomori, Narita, Chiba, 286-8686, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy at Narita, International University of Health and Welfare, 4-3 Kozunomori, Narita, Chiba, 286-8686, Japan","institution_ids":["https://openalex.org/I79072001"]}]},{"author_position":"last","author":{"id":null,"display_name":"Kenji Sumiya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79746392","display_name":"IRYO Sosei University","ror":"https://ror.org/04v5axh10","country_code":"JP","type":"education","lineage":["https://openalex.org/I79746392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Sumiya","raw_affiliation_strings":["Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Iryo Sosei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima, 970-8551, Japan","institution_ids":["https://openalex.org/I79746392"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5102003094"],"corresponding_institution_ids":["https://openalex.org/I79072001"],"apc_list":{"value":2490,"currency":"USD","value_usd":2490},"apc_paid":{"value":2490,"currency":"USD","value_usd":2490},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.8198000192642212,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.8198000192642212,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10508","display_name":"Patient Safety and Medication Errors","score":0.02070000022649765,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tablet-disintegration","display_name":"tablet disintegration","score":0.7110000252723694},{"id":"https://openalex.org/keywords/drug-compatibility","display_name":"drug compatibility","score":0.4740000069141388},{"id":"https://openalex.org/keywords/gastrointestinal-retention","display_name":"gastrointestinal retention","score":0.7820000052452087},{"id":"https://openalex.org/keywords/computed-tomography-findings","display_name":"computed tomography findings","score":0.6850000023841858},{"id":"https://openalex.org/keywords/simulated-gastric-fluid","display_name":"simulated gastric fluid","score":0.6690000295639038},{"id":"https://openalex.org/keywords/simulated-intestinal-fluid","display_name":"simulated intestinal fluid","score":0.9629999995231628},{"id":"https://openalex.org/keywords/pharmacist-review","display_name":"pharmacist review","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.892300009727478},{"id":"https://openalex.org/C543218039","wikidata":"https://www.wikidata.org/wiki/Q660","display_name":"Magnesium","level":2,"score":0.5328999757766724},{"id":"https://openalex.org/C3018292220","wikidata":"https://www.wikidata.org/wiki/Q846270","display_name":"Gastric fluid","level":2,"score":0.5144000053405762},{"id":"https://openalex.org/C43376680","wikidata":"https://www.wikidata.org/wiki/Q6580786","display_name":"Bolus (digestion)","level":2,"score":0.4959999918937683},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.459199994802475},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.43299999833106995},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.43209999799728394},{"id":"https://openalex.org/C44315111","wikidata":"https://www.wikidata.org/wiki/Q1344580","display_name":"Enteral administration","level":3,"score":0.3959999978542328},{"id":"https://openalex.org/C78722104","wikidata":"https://www.wikidata.org/wiki/Q21653202","display_name":"Parenteral nutrition","level":2,"score":0.3840000033378601},{"id":"https://openalex.org/C77281830","wikidata":"https://www.wikidata.org/wiki/Q718608","display_name":"Dosage form","level":2,"score":0.3725999891757965},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3695000112056732},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2831999957561493},{"id":"https://openalex.org/C3019981671","wikidata":"https://www.wikidata.org/wiki/Q5165929","display_name":"Immediate release","level":2,"score":0.2711000144481659},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2639000117778778}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s40780-026-00620-z","doi":"https://doi.org/10.1186/s40780-026-00620-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40780-026-00620-z","pdf_url":null,"source":{"id":"https://openalex.org/S2737624436","display_name":"Journal of Pharmaceutical Health Care and Sciences","issn_l":"2055-0294","issn":["2055-0294"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","oarl","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Health Care and Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s40780-026-00620-z","doi":"https://doi.org/10.1186/s40780-026-00620-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40780-026-00620-z","pdf_url":null,"source":{"id":"https://openalex.org/S2737624436","display_name":"Journal of Pharmaceutical Health Care and Sciences","issn_l":"2055-0294","issn":["2055-0294"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","oarl","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Health Care and Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W595791996","https://openalex.org/W3091472623","https://openalex.org/W3212712859","https://openalex.org/W6967116112","https://openalex.org/W1988833935","https://openalex.org/W2963729557","https://openalex.org/W2106483728","https://openalex.org/W1999685453","https://openalex.org/W1965074576","https://openalex.org/W3146724210"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Concentrated":[2],"oral":[3,124,242],"enteral":[4],"nutrition":[5],"(EN)":[6],"formulas":[7],"are":[8,234],"used":[9],"when":[10,231],"adequate":[11],"energy":[12],"intake":[13],"is":[14],"required":[15],"despite":[16],"limited":[17],"feeding":[18],"volume,":[19,227],"but":[20,204],"their":[21],"compatibility":[22],"with":[23,81,114,159,237],"tablets":[24,44,96,167,188,233],"has":[25],"not":[26,200],"been":[27],"fully":[28],"evaluated.":[29],"We":[30],"observed":[31],"computed":[32],"tomography":[33],"(CT)":[34],"findings":[35,157,217],"suggestive":[36],"of":[37,40,75,83,221],"gastrointestinal":[38],"retention":[39],"magnesium":[41],"oxide":[42],"(MgO)":[43],"in":[45,56,89,92,104,129,213],"an":[46,54,84],"older":[47],"inpatient":[48],"receiving":[49],"concentrated":[50,123,241],"EN":[51,125,243],"and":[52,64,73,110,154,228],"performed":[53],"exploratory":[55],"vitro":[57,93,214],"disintegration":[58,102,128,178],"study.":[59],"Methods":[60],"Clinical":[61],"medication,":[62],"nutrition,":[63],"CT":[65,71,144],"data":[66],"were":[67,79,97,140],"reviewed":[68],"retrospectively.":[69],"The":[70],"attenuation":[72],"diameter":[74],"intraluminal":[76,149],"tablet-like":[77],"structures":[78,150],"compared":[80],"those":[82],"intact":[85],"MgO":[86,95,162,166,232],"tablet":[87],"scanned":[88],"water.":[90],"For":[91],"testing,":[94],"evaluated":[98],"using":[99],"Japanese":[100],"Pharmacopoeia-based":[101],"testing":[103],"purified":[105],"water,":[106],"simulated":[107,111],"gastric":[108],"fluid,":[109,113],"intestinal":[112],"or":[115],"without":[116],"30-min":[117],"pre-exposure":[118,173],"to":[119,174,181],"Recovery":[120,130,175,185,238],"K5,":[121,176,239],"a":[122,136,207,240],"formula.":[126,244],"Direct":[127],"K5":[131,186],"was":[132],"also":[133],"examined":[134],"as":[135],"worst-case":[137],"condition.":[138],"Results":[139,143],"summarized":[141],"descriptively.":[142],"showed":[145],"three":[146],"discrete":[147],"high-attenuation":[148],"measuring":[151],"9.0\u20139.4":[152],"mm":[153],"501\u2013880":[155],"HU,":[156],"compatible":[158],"suspected":[160],"undisintegrated":[161],"tablets.":[163],"Without":[164],"pre-exposure,":[165],"disintegrated":[168,191],"within":[169],"8\u201310":[170],"s.":[171,183,194],"After":[172],"mean":[177],"times":[179],"increased":[180],"338.5\u2013422.2":[182],"In":[184],"itself,":[187],"remained":[189],"incompletely":[190],"beyond":[192],"10,020":[193],"Conclusions":[195],"This":[196],"brief":[197],"report":[198],"does":[199],"establish":[201],"definitive":[202],"causality,":[203],"it":[205],"identifies":[206],"clinically":[208],"relevant":[209],"signal":[210],"supported":[211],"by":[212],"evidence.":[215],"These":[216],"support":[218],"pharmacist-led":[219],"review":[220],"the":[222],"actual":[223],"administration":[224],"sequence,":[225],"water":[226],"dosage-form":[229],"selection":[230],"administered":[235],"concomitantly":[236]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2026-09-04T00:00:00"}