{"id":"https://openalex.org/W7207783410","doi":"https://doi.org/10.3389/fneur.2026.1801275","title":"The clinical features of anti-CNTN1 antibodies associated autoimmune nodopathies with nephropathy: a case series","display_name":"The clinical features of anti-CNTN1 antibodies associated autoimmune nodopathies with nephropathy: a case series","publication_year":2026,"publication_date":"2026-09-03","ids":{"openalex":"https://openalex.org/W7207783410","doi":"https://doi.org/10.3389/fneur.2026.1801275","pmid":"https://pubmed.ncbi.nlm.nih.gov/42755838","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13581875"},"language":"en","primary_location":{"id":"doi:10.3389/fneur.2026.1801275","doi":"https://doi.org/10.3389/fneur.2026.1801275","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1801275","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1801275/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1801275/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5143418636","display_name":"Jinping Wan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115210","display_name":"Guigang City People's Hospital","ror":"https://ror.org/0247xas18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115210"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinping Wan","raw_affiliation_strings":["Department of Neurology, Guigang City People\u2019s Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Guigang City People\u2019s Hospital","institution_ids":["https://openalex.org/I4210115210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124726623","display_name":"Tiegen Xiong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tiegen Xiong","raw_affiliation_strings":["Department of Neurology, General Hospital of Southern Theater Command"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, General Hospital of Southern Theater Command","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050531186","display_name":"Jianian Hu","orcid":"https://orcid.org/0000-0001-9915-9983","observed_orcids":["https://orcid.org/0000-0001-9915-9983"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianian Hu","raw_affiliation_strings":["Department of Neurology, Huashan Hospital, Fudan University","National Center for Neurological Disorders (NCND)","Rare Disease Center, Huashan Hospital, Fudan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]},{"raw_affiliation_string":"National Center for Neurological Disorders (NCND)","institution_ids":[]},{"raw_affiliation_string":"Rare Disease Center, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137939935","display_name":"Shaojun Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaojun Liu","raw_affiliation_strings":["Department of Nephrology, Huashan Hospital, Fudan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149919200","display_name":"Jie Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Lin","raw_affiliation_strings":["Department of Neurology, Huashan Hospital, Fudan University","National Center for Neurological Disorders (NCND)","Rare Disease Center, Huashan Hospital, Fudan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]},{"raw_affiliation_string":"National Center for Neurological Disorders (NCND)","institution_ids":[]},{"raw_affiliation_string":"Rare Disease Center, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045268007","display_name":"Chongbo Zhao","orcid":"https://orcid.org/0000-0001-9481-1418","observed_orcids":["https://orcid.org/0000-0001-9481-1418"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chongbo Zhao","raw_affiliation_strings":["Department of Neurology, Huashan Hospital, Fudan University","National Center for Neurological Disorders (NCND)","Rare Disease Center, Huashan Hospital, Fudan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]},{"raw_affiliation_string":"National Center for Neurological Disorders (NCND)","institution_ids":[]},{"raw_affiliation_string":"Rare Disease Center, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026840794","display_name":"Chong Sun","orcid":"https://orcid.org/0000-0001-9008-2158","observed_orcids":["https://orcid.org/0000-0001-9008-2158"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chong Sun","raw_affiliation_strings":["Department of Neurology, Huashan Hospital, Fudan University","National Center for Neurological Disorders (NCND)","Rare Disease Center, Huashan Hospital, Fudan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]},{"raw_affiliation_string":"National Center for Neurological Disorders (NCND)","institution_ids":[]},{"raw_affiliation_string":"Rare Disease Center, Huashan Hospital, Fudan University","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5159765636","display_name":"Hai Xiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115210","display_name":"Guigang City People's Hospital","ror":"https://ror.org/0247xas18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115210"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hai Xiao","raw_affiliation_strings":["Department of Neurology, Guigang City People\u2019s Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Guigang City People\u2019s Hospital","institution_ids":["https://openalex.org/I4210115210"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5026840794","https://openalex.org/A5159765636"],"corresponding_institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210115210","https://openalex.org/I4210159575"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.65886695,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":null,"first_page":"1801275","last_page":"1801275"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":0.7339000105857849,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":0.7339000105857849,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11627","display_name":"Autoimmune Neurological Disorders and Treatments","score":0.17749999463558197,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.030500000342726707,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contactin-1","display_name":"contactin-1","score":0.8519999980926514},{"id":"https://openalex.org/keywords/autoimmune-nodopathy","display_name":"autoimmune nodopathy","score":0.875},{"id":"https://openalex.org/keywords/immune-mediated-neuropathy","display_name":"autoimmune neuropathy","score":0.5139999985694885},{"id":"https://openalex.org/keywords/kidney-disease","display_name":"kidney disease","score":0.7390000224113464},{"id":"https://openalex.org/keywords/membranous-nephropathy","display_name":"membranous nephropathy","score":0.9919999837875366},{"id":"https://openalex.org/keywords/lupus-nephritis","display_name":"lupus nephritis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/kidney-biopsy","display_name":"renal biopsy","score":0.46700000762939453},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.5820000171661377},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.8870000243186951},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5429999828338623},{"id":"https://openalex.org/keywords/autoantibodies","display_name":"autoantibodies","score":0.5},{"id":"https://openalex.org/keywords/autoimmune-encephalomyelitis","display_name":"autoimmune encephalomyelitis","score":0.5509999990463257},{"id":"https://openalex.org/keywords/neuromyelitis-optica-spectrum-disorder","display_name":"neuromyelitis optica spectrum disorder","score":0.75},{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.38499999046325684}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8720999956130981},{"id":"https://openalex.org/C2779384505","wikidata":"https://www.wikidata.org/wiki/Q17007513","display_name":"Concomitant","level":2,"score":0.7217000126838684},{"id":"https://openalex.org/C2779912601","wikidata":"https://www.wikidata.org/wiki/Q1621830","display_name":"Lupus nephritis","level":3,"score":0.6761999726295471},{"id":"https://openalex.org/C2781184683","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Nephropathy","level":3,"score":0.597100019454956},{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.5460000038146973},{"id":"https://openalex.org/C133397671","wikidata":"https://www.wikidata.org/wiki/Q3347171","display_name":"Renal pathology","level":3,"score":0.5364999771118164},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5236999988555908},{"id":"https://openalex.org/C2781087799","wikidata":"https://www.wikidata.org/wiki/Q7312483","display_name":"Renal biopsy","level":3,"score":0.5167999863624573},{"id":"https://openalex.org/C2775946357","wikidata":"https://www.wikidata.org/wiki/Q1713037","display_name":"Membranous nephropathy","level":4,"score":0.512499988079071},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5019000172615051},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.49149999022483826},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4887999892234802},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.47679999470710754},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.448199987411499},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.44609999656677246},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4198000133037567},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.4171000123023987},{"id":"https://openalex.org/C2780368995","wikidata":"https://www.wikidata.org/wiki/Q605006","display_name":"Glomerulonephritis","level":3,"score":0.4009000062942505},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.38449999690055847},{"id":"https://openalex.org/C2777058396","wikidata":"https://www.wikidata.org/wiki/Q401402","display_name":"Nephritis","level":2,"score":0.38350000977516174},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.35929998755455017},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.314300000667572},{"id":"https://openalex.org/C529978579","wikidata":"https://www.wikidata.org/wiki/Q499500","display_name":"Clinical pathology","level":2,"score":0.31119999289512634},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.2987000048160553},{"id":"https://openalex.org/C2778415529","wikidata":"https://www.wikidata.org/wiki/Q1435223","display_name":"Focal segmental glomerulosclerosis","level":4,"score":0.2888000011444092},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.2759000062942505},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.2694000005722046},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.26570001244544983},{"id":"https://openalex.org/C2984894117","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Indirect immunofluorescence","level":3,"score":0.257999986410141}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058967","descriptor_name":"Contactin 1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3389/fneur.2026.1801275","doi":"https://doi.org/10.3389/fneur.2026.1801275","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1801275","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1801275/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},{"id":"pmid:42755838","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42755838","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neurology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13581875","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13581875/pdf/fneur-17-1801275.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neurol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:aec7816f49f74985818a2f3ccd499056","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/aec7816f49f74985818a2f3ccd499056","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology, Vol 17 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fneur.2026.1801275","doi":"https://doi.org/10.3389/fneur.2026.1801275","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1801275","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1801275/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7207783410.pdf","grobid_xml":"https://content.openalex.org/works/W7207783410.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1566573763","https://openalex.org/W2125799629","https://openalex.org/W2313719618","https://openalex.org/W2494661094","https://openalex.org/W2619739653","https://openalex.org/W2902779939","https://openalex.org/W2903203163","https://openalex.org/W2966041078","https://openalex.org/W3186729348","https://openalex.org/W3202563226","https://openalex.org/W3204276748","https://openalex.org/W4292590086","https://openalex.org/W4298086961","https://openalex.org/W4306315823","https://openalex.org/W4323653749","https://openalex.org/W4327722709","https://openalex.org/W4376872870","https://openalex.org/W4387935360","https://openalex.org/W4392299224","https://openalex.org/W4400447482","https://openalex.org/W4410288096","https://openalex.org/W4411395106"],"related_works":["https://openalex.org/W4402655413","https://openalex.org/W7124431351","https://openalex.org/W3202563226","https://openalex.org/W7161779150","https://openalex.org/W4404765937","https://openalex.org/W4323665740","https://openalex.org/W4323653749","https://openalex.org/W7169675741","https://openalex.org/W3127112109","https://openalex.org/W4416289934"],"abstract_inverted_index":{"Objective":[0],"The":[1,77],"concurrence":[2],"of":[3,35,79,124,136,162,239,262,277],"anti-contactin-1":[4],"(CNTN1)":[5],"antibody-associated":[6,37,113,249,255,306],"autoimmune":[7,146],"nodopathies":[8],"(AN)":[9],"and":[10,32,69,75,97,144,170,210,214,229,280,308],"nephropathy":[11,171,224,263],"has":[12],"been":[13],"sporadically":[14],"reported,":[15],"though":[16],"the":[17,29,115,315],"underlying":[18,316],"relationship":[19,303],"remains":[20],"unclear.":[21],"This":[22,154],"case":[23,44],"series":[24,45],"study":[25],"aimed":[26],"to":[27,103,109,186,199,265,290,313],"investigate":[28],"clinical":[30],"characteristics":[31],"renal":[33,70,105],"pathology":[34,283],"anti-CNTN1":[36,61,116,179,248,269,305],"AN":[38,250,256,267,279,307],"with":[39,52,95,111,190,202,247,251],"nephropathy.":[40,188,281],"Methods":[41],"A":[42],"retrospective":[43],"was":[46,82,242],"conducted":[47],"including":[48,100],"69":[49],"patients":[50,57,110,221,246,257,286],"diagnosed":[51],"AN,":[53,114],"among":[54],"whom":[55],"11":[56],"tested":[58],"positive":[59,145,207,243],"for":[60],"antibodies.":[62,270],"Clinical":[63],"manifestations,":[64],"electrophysiological":[65],"data,":[66],"laboratory":[67],"results,":[68],"biopsy":[71,218],"findings":[72,298],"were":[73,90,183],"collected":[74],"analyzed.":[76],"presence":[78],"nodal/paranodal":[80],"antibodies":[81,147],"confirmed":[83],"using":[84],"serum":[85],"cell-based":[86],"assays.":[87],"Renal":[88,217,282],"biopsies":[89],"performed":[91],"in":[92,219,226,233,245,284],"four":[93,220],"patients,":[94,181],"immunohistochemical":[96],"immunofluorescence":[98],"staining,":[99,102],"CNTN1":[101,237],"characterize":[104],"pathology.":[106],"Results":[107],"Compared":[108],"non-anti-CNTN1":[112],"antibody":[117],"group":[118,155],"had":[119],"a":[120,158,203,259,273,300],"significantly":[121],"lower":[122],"proportion":[123],"males":[125],"(54.5%":[126],"vs.":[127,139,149,165,173],"84.5%,":[128],"p":[129,141,151,167,175],"=":[130,142],"0.024)":[131],"but":[132,292],"showed":[133],"higher":[134,160,260,275],"rates":[135],"hypertension":[137],"(36.4%":[138],"8.6%,":[140],"0.021)":[143],"(50%":[148],"5%,":[150],"<":[152,168,176],"0.001).":[153,177],"also":[156,294],"exhibited":[157,193],"markedly":[159],"prevalence":[161,261],"proteinuria":[163],"(63.6%":[164,172],"10.3%,":[166],"0.001)":[169],"3.4%,":[174],"Among":[178],"antibody-positive":[180],"females":[182],"more":[184],"prone":[185],"concomitant":[187],"Patients":[189],"both":[191],"conditions":[192],"onset":[194],"ages":[195],"ranging":[196],"from":[197],"17":[198],"67":[200],"years,":[201],"chronic":[204],"course,":[205],"frequent":[206],"Romberg\u2019s":[208],"sign,":[209],"prolonged":[211],"distal":[212],"motor":[213],"F-wave":[215],"latencies.":[216],"revealed":[222],"membranous":[223],"(MN)":[225],"three":[227],"cases":[228],"lupus":[230],"nephritis":[231],"(LN)":[232],"one":[234],"case.":[235],"Notably,":[236],"staining":[238],"kidney":[240],"tissue":[241],"only":[244],"MN.":[252],"Conclusion":[253],"Anti-CNTN1":[254],"have":[258],"compared":[264],"those":[266],"without":[268],"Females":[271],"demonstrate":[272],"particularly":[274],"risk":[276],"comorbid":[278],"these":[285],"is":[287],"not":[288],"limited":[289],"MN":[291],"can":[293],"include":[295],"LN.":[296],"These":[297],"highlight":[299],"complex":[301],"immunopathological":[302],"between":[304],"nephropathy,":[309],"warranting":[310],"further":[311],"studies":[312],"understand":[314],"mechanisms.":[317]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-09-04T00:00:00"}