{"id":"https://openalex.org/W7207623016","doi":"https://doi.org/10.1186/s42494-026-00277-z","title":"A decade later: a longitudinal retrospective cohort study of the clinical course of childhood-onset epilepsy in a multi-ethnic tertiary centre","display_name":"A decade later: a longitudinal retrospective cohort study of the clinical course of childhood-onset epilepsy in a multi-ethnic tertiary centre","publication_year":2026,"publication_date":"2026-09-04","ids":{"openalex":"https://openalex.org/W7207623016","doi":"https://doi.org/10.1186/s42494-026-00277-z","pmid":"https://pubmed.ncbi.nlm.nih.gov/42698113","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13543515"},"language":"en","primary_location":{"id":"doi:10.1186/s42494-026-00277-z","doi":"https://doi.org/10.1186/s42494-026-00277-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s42494-026-00277-z","pdf_url":"https://link.springer.com/content/pdf/10.1186/s42494-026-00277-z.pdf","source":{"id":"https://openalex.org/S4210211745","display_name":"Acta Epileptologica","issn_l":"2524-4434","issn":["2524-4434","2096-9384"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Epileptologica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://link.springer.com/content/pdf/10.1186/s42494-026-00277-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5149683423","display_name":"Jen Ern Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Jen Ern Tan","raw_affiliation_strings":["Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia","Neurology Unit, Paediatric Department, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]},{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia","institution_ids":[]},{"raw_affiliation_string":"Neurology Unit, Paediatric Department, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102754065","display_name":"Juen Kiem Tan","orcid":"https://orcid.org/0000-0001-8904-9799","observed_orcids":["https://orcid.org/0000-0001-8904-9799"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Juen Kiem Tan","raw_affiliation_strings":["Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia","Neurology Unit, Paediatric Department, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]},{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia","institution_ids":[]},{"raw_affiliation_string":"Neurology Unit, Paediatric Department, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113001958","display_name":"Michelle Maryanne Tan","orcid":"https://orcid.org/0009-0000-9823-9607","observed_orcids":["https://orcid.org/0009-0000-9823-9607"]},"institutions":[{"id":"https://openalex.org/I4210156005","display_name":"Tengku Ampuan Rahimah Hospital","ror":"https://ror.org/05c0hj959","country_code":"MY","type":"healthcare","lineage":["https://openalex.org/I4210156005"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Michelle Maryanne Tan","raw_affiliation_strings":["Department of Medicine, Hospital Tengku Ampuan Rahimah, Selangor, 41200, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Hospital Tengku Ampuan Rahimah, Selangor, 41200, Malaysia","institution_ids":["https://openalex.org/I4210156005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020918039","display_name":"Zhi Xuan Ng","orcid":"https://orcid.org/0000-0003-1277-5754","observed_orcids":["https://orcid.org/0000-0003-1277-5754"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Zhi Xuan Ng","raw_affiliation_strings":["Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130786261","display_name":"Zhee Yee Chan","orcid":"https://orcid.org/0009-0002-9748-1148","observed_orcids":["https://orcid.org/0009-0002-9748-1148"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Zhee Yee Chan","raw_affiliation_strings":["Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130777723","display_name":"Zi Qi Ang","orcid":"https://orcid.org/0009-0000-2261-0561","observed_orcids":["https://orcid.org/0009-0000-2261-0561"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Zi Qi Ang","raw_affiliation_strings":["Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140323021","display_name":"Nur Arifah Mohd Khaili","orcid":"https://orcid.org/0009-0000-4104-3443","observed_orcids":["https://orcid.org/0009-0000-4104-3443"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nur Arifah Mohd Khaili","raw_affiliation_strings":["Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149799078","display_name":"Nur Liyana Rahmat","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nur Liyana Rahmat","raw_affiliation_strings":["Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149633106","display_name":"Jasmine Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801594805","display_name":"University Kebangsaan Malaysia Medical Centre","ror":"https://ror.org/01590nj79","country_code":"MY","type":"healthcare","lineage":["https://openalex.org/I2801594805"]},{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Jasmine Lee","raw_affiliation_strings":["Paediatric Department, Faculty of Medicine, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Paediatric Department, Faculty of Medicine, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I2801594805","https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068380400","display_name":"Ching Soong Khoo","orcid":"https://orcid.org/0000-0002-6756-0411","observed_orcids":["https://orcid.org/0000-0002-6756-0411"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Ching Soong Khoo","raw_affiliation_strings":["Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia. cskhoo@ukm.edu.my","Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia. cskhoo@ukm.edu.my"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia. cskhoo@ukm.edu.my","institution_ids":["https://openalex.org/I885383172"]},{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia. cskhoo@ukm.edu.my","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076873364","display_name":"Hui Jan Tan","orcid":"https://orcid.org/0000-0003-4827-7984","observed_orcids":["https://orcid.org/0000-0003-4827-7984"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Hui Jan Tan","raw_affiliation_strings":["Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]},{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109442962","display_name":"Sau Wei Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Sau Wei Wong","raw_affiliation_strings":["Neurology Unit, Paediatric Department, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Unit, Paediatric Department, Hospital Tunku Ampuan Besar Tuanku Aishah Rohani, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5068380400"],"corresponding_institution_ids":["https://openalex.org/I885383172"],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12267","display_name":"Diet and metabolism studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/childhood-onset-epilepsy","display_name":"childhood-onset epilepsy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.7440000176429749},{"id":"https://openalex.org/keywords/seizure-control","display_name":"seizure control","score":0.8209999799728394},{"id":"https://openalex.org/keywords/neurodevelopmental-outcomes","display_name":"neurodevelopmental outcomes","score":0.7710000276565552},{"id":"https://openalex.org/keywords/psychosocial-outcomes","display_name":"psychosocial outcomes","score":0.7929999828338623},{"id":"https://openalex.org/keywords/intellectual-disability","display_name":"intellectual disability","score":0.8920000195503235},{"id":"https://openalex.org/keywords/learning-disabilities","display_name":"learning disabilities","score":0.7450000047683716},{"id":"https://openalex.org/keywords/behavioral-problems","display_name":"behavioral problems","score":0.9819999933242798},{"id":"https://openalex.org/keywords/special-education","display_name":"special education","score":0.8939999938011169},{"id":"https://openalex.org/keywords/transition-to-adult-care","display_name":"transition to adult care","score":0.6990000009536743},{"id":"https://openalex.org/keywords/focal-seizures","display_name":"focal seizures","score":0.7799999713897705},{"id":"https://openalex.org/keywords/multidisciplinary-management","display_name":"multidisciplinary management","score":0.7929999828338623}],"concepts":[{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.869700014591217},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7576000094413757},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.7294999957084656},{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.6528000235557556},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.6279000043869019},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6011000275611877},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5199000239372253},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.511900007724762},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.44190001487731934},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.4302000105381012},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.4207000136375427},{"id":"https://openalex.org/C2778734009","wikidata":"https://www.wikidata.org/wiki/Q55785625","display_name":"Epilepsy syndromes","level":3,"score":0.3598000109195709},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.3522000014781952},{"id":"https://openalex.org/C2780874087","wikidata":"https://www.wikidata.org/wiki/Q7447057","display_name":"Seizure types","level":3,"score":0.34200000762939453},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.32440000772476196},{"id":"https://openalex.org/C2780145166","wikidata":"https://www.wikidata.org/wiki/Q5382985","display_name":"Epilepsy in children","level":3,"score":0.32350000739097595},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.320499986410141},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.30059999227523804},{"id":"https://openalex.org/C2779746230","wikidata":"https://www.wikidata.org/wiki/Q15752159","display_name":"Pediatric Neurology","level":2,"score":0.2847999930381775},{"id":"https://openalex.org/C22467394","wikidata":"https://www.wikidata.org/wiki/Q849359","display_name":"Multidisciplinary approach","level":2,"score":0.2822999954223633},{"id":"https://openalex.org/C2780803581","wikidata":"https://www.wikidata.org/wiki/Q1347108","display_name":"Epilepsy surgery","level":3,"score":0.2784999907016754},{"id":"https://openalex.org/C551499885","wikidata":"https://www.wikidata.org/wiki/Q183560","display_name":"Intellectual disability","level":2,"score":0.27790001034736633}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/s42494-026-00277-z","doi":"https://doi.org/10.1186/s42494-026-00277-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s42494-026-00277-z","pdf_url":"https://link.springer.com/content/pdf/10.1186/s42494-026-00277-z.pdf","source":{"id":"https://openalex.org/S4210211745","display_name":"Acta Epileptologica","issn_l":"2524-4434","issn":["2524-4434","2096-9384"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Epileptologica","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13543515","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13543515/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13543515/pdf/42494_2026_Article_277.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Epileptol","raw_type":"Text"},{"id":"pmid:42698113","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42698113","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta epileptologica","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s42494-026-00277-z","doi":"https://doi.org/10.1186/s42494-026-00277-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s42494-026-00277-z","pdf_url":"https://link.springer.com/content/pdf/10.1186/s42494-026-00277-z.pdf","source":{"id":"https://openalex.org/S4210211745","display_name":"Acta Epileptologica","issn_l":"2524-4434","issn":["2524-4434","2096-9384"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Epileptologica","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7207623016.pdf","grobid_xml":"https://content.openalex.org/works/W7207623016.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1920696238","https://openalex.org/W1966728711","https://openalex.org/W1969154371","https://openalex.org/W1976459342","https://openalex.org/W1978437325","https://openalex.org/W1983444163","https://openalex.org/W1983724066","https://openalex.org/W2064593217","https://openalex.org/W2067117895","https://openalex.org/W2085476870","https://openalex.org/W2099263404","https://openalex.org/W2107474649","https://openalex.org/W2114838471","https://openalex.org/W2137193274","https://openalex.org/W2143807346","https://openalex.org/W2150228656","https://openalex.org/W2300818303","https://openalex.org/W2334049603","https://openalex.org/W2547473047","https://openalex.org/W2553292166","https://openalex.org/W2563036039","https://openalex.org/W2588461074","https://openalex.org/W2744012576","https://openalex.org/W2746624543","https://openalex.org/W2768228597","https://openalex.org/W2888327773","https://openalex.org/W2903306471","https://openalex.org/W2966625763","https://openalex.org/W3021793483","https://openalex.org/W3033498571","https://openalex.org/W3095617386","https://openalex.org/W3112514489","https://openalex.org/W3119970822","https://openalex.org/W3132317855","https://openalex.org/W3137407127","https://openalex.org/W3203203665","https://openalex.org/W3209609900","https://openalex.org/W4225006941","https://openalex.org/W4285005690","https://openalex.org/W4292805468","https://openalex.org/W4311020989","https://openalex.org/W4318464257","https://openalex.org/W4382345377","https://openalex.org/W4402854708","https://openalex.org/W4404869946"],"related_works":["https://openalex.org/W2568271088","https://openalex.org/W4412392951","https://openalex.org/W1985226886","https://openalex.org/W2549260667","https://openalex.org/W2150228656","https://openalex.org/W3137407127","https://openalex.org/W2105574344","https://openalex.org/W2079755662","https://openalex.org/W3003473798","https://openalex.org/W3125081545"],"abstract_inverted_index":{"BACKGROUND:":[0],"Epilepsy":[1],"affects":[2],"a":[3,18,115,173],"significant":[4,175],"proportion":[5],"of":[6,20,29,41,92,105,121,139,143,145],"people":[7],"globally,":[8],"with":[9,96,114,132,149,153,158,192,200],"many":[10],"cases":[11],"beginning":[12],"in":[13,165,177],"childhood.":[14],"However,":[15],"there":[16],"is":[17,198],"lack":[19],"longitudinal":[21],"studies":[22],"exploring":[23],"the":[24,39,106,127,136,181,210],"long-term":[25,202],"outcomes":[26,49],"and":[27,48,66,71,81,156,185,204,216],"characteristics":[28,47],"childhood-onset":[30,42],"epilepsy":[31,43,97,119,197],"into":[32,238],"adulthood.":[33,239],"This":[34,57],"study":[35,60],"aimed":[36],"to":[37,44,223,231],"analyze":[38],"trajectory":[40],"identify":[45],"particular":[46],"that":[50],"could":[51],"help":[52],"guide":[53],"future":[54],"management.":[55],"METHODS:":[56],"retrospective":[58],"cohort":[59,107],"was":[61,108],"conducted":[62],"between":[63],"June":[64],"2021":[65],"December":[67],"2022":[68],"at":[69,118],"adult":[70,224],"paediatric":[72,222],"clinics.":[73],"Participant":[74],"data":[75],"were":[76,100,126,147,189],"obtained":[77],"from":[78,221],"medical":[79],"records":[80],"corroborated":[82],"through":[83],"history":[84],"taking":[85],"during":[86],"follow-up":[87,183],"visits.":[88],"RESULTS:":[89],"A":[90,141],"total":[91,142],"100":[93],"participants":[94,146],"diagnosed":[95],"since":[98],"childhood":[99],"included.":[101],"The":[102],"mean":[103,116],"age":[104,117],"23.15":[109],"(SD":[110],"=":[111],"8.80)":[112],"years,":[113],"diagnosis":[120],"3.97":[122],"years.":[123],"Focal":[124],"seizures":[125],"most":[128],"prevalent":[129],"type":[130],"(53%),":[131],"structural":[133],"causes":[134],"being":[135],"predominant":[137],"aetiology":[138],"epilepsy.":[140],"48%":[144],"identified":[148],"intellectual":[150],"disabilities,":[151,155],"24%":[152],"learning":[154],"32%":[157],"behavioural":[159],"difficulties.":[160],"Consequently,":[161],"45%":[162],"required":[163],"enrollment":[164],"special":[166],"education":[167],"institutions.":[168],"We":[169,227],"did":[170],"not":[171],"observe":[172],"statistically":[174],"difference":[176],"seizure":[178,193],"control":[179],"over":[180],"10-year":[182],"period,":[184],"no":[186],"analyzed":[187],"factors":[188],"significantly":[190],"associated":[191,199],"control.":[194],"CONCLUSIONS:":[195],"Childhood-onset":[196],"substantial":[201],"neurodevelopmental":[203],"psychosocial":[205],"consequences.":[206],"Our":[207],"findings":[208],"highlight":[209],"need":[211],"for":[212],"individualized,":[213],"multidisciplinary":[214],"management":[215,234],"clear,":[217],"structured":[218],"transition":[219,237],"pathways":[220],"neurology":[225],"services.":[226],"outline":[228],"several":[229],"recommendations":[230],"enhance":[232],"overall":[233],"as":[235],"patients":[236]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-09-04T00:00:00"}