{"id":"https://openalex.org/W7207567280","doi":"https://doi.org/10.14300/mnnc.2026.21025","title":"Features of angiogenesis of colorectal carcinoma","display_name":"Features of angiogenesis of colorectal carcinoma","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7207567280","doi":"https://doi.org/10.14300/mnnc.2026.21025"},"language":"en","primary_location":{"id":"doi:10.14300/mnnc.2026.21025","doi":"https://doi.org/10.14300/mnnc.2026.21025","is_oa":true,"landing_page_url":"https://doi.org/10.14300/mnnc.2026.21025","pdf_url":"https://medvestnik.stgmu.ru/files/articles/1658.pdf","source":{"id":"https://openalex.org/S4210168183","display_name":"Medical news of the North Caucasus","issn_l":"2073-8137","issn":["2073-8137","2073-8145"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical news of the North Caucasus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://medvestnik.stgmu.ru/files/articles/1658.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079149696","display_name":"B. D. Seferov","orcid":"https://orcid.org/0000-0003-0191-7665","observed_orcids":["https://orcid.org/0000-0003-0191-7665"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bekir Seferov","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0191-7665","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024836963","display_name":"Elena Petrovna Golubinskaya","orcid":"https://orcid.org/0000-0003-3917-924X","observed_orcids":["https://orcid.org/0000-0003-3917-924X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elena Petrovna Golubinskaya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071176383","display_name":"Julianna Arkadevna Yermola","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julianna Arkadevna Yermola","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090642188","display_name":"Anatoly Vladimirovich Kubyshkin","orcid":"https://orcid.org/0000-0002-1309-4005","observed_orcids":["https://orcid.org/0000-0002-1309-4005"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anatoly Vladimirovich Kubyshkin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019134159","display_name":"Evgeniya Yurievna Zyablitskaya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Evgeniya Yurievna Zyablitskaya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5024612179","display_name":"Vladimir Anatolievich Kubyshkin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vladimir Anatolievich Kubyshkin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3024,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.71682836,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"21","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9810000061988831},{"id":"https://openalex.org/keywords/tumor-angiogenesis","display_name":"tumor angiogenesis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.7049999833106995},{"id":"https://openalex.org/keywords/hif-1alpha","display_name":"HIF-1\u03b1","score":0.628000020980835},{"id":"https://openalex.org/keywords/vegf-a","display_name":"VEGF-A","score":1.0},{"id":"https://openalex.org/keywords/angiopoietin-1","display_name":"angiopoietin-1","score":0.8519999980926514},{"id":"https://openalex.org/keywords/angiopoietin-2","display_name":"angiopoietin-2","score":1.0},{"id":"https://openalex.org/keywords/tie2","display_name":"Tie2","score":0.9549999833106995},{"id":"https://openalex.org/keywords/metastatic-colorectal-cancer","display_name":"metastatic colorectal cancer","score":0.7799999713897705},{"id":"https://openalex.org/keywords/immunophenotype","display_name":"immunophenotype","score":0.7059999704360962},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7889999747276306},{"id":"https://openalex.org/keywords/personalized-treatment","display_name":"personalized treatment","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7494999766349792},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.7196000218391418},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6567000150680542},{"id":"https://openalex.org/C31194975","wikidata":"https://www.wikidata.org/wiki/Q20970095","display_name":"HIF1A","level":3,"score":0.633400022983551},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4772000014781952},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4027000069618225},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.3675000071525574},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3522000014781952},{"id":"https://openalex.org/C85219853","wikidata":"https://www.wikidata.org/wiki/Q4763284","display_name":"Angiopoietin receptor","level":3,"score":0.34220001101493835},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.3149999976158142},{"id":"https://openalex.org/C2909234372","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal adenocarcinoma","level":4,"score":0.29739999771118164},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.2854999899864197}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.14300/mnnc.2026.21025","doi":"https://doi.org/10.14300/mnnc.2026.21025","is_oa":true,"landing_page_url":"https://doi.org/10.14300/mnnc.2026.21025","pdf_url":"https://medvestnik.stgmu.ru/files/articles/1658.pdf","source":{"id":"https://openalex.org/S4210168183","display_name":"Medical news of the North Caucasus","issn_l":"2073-8137","issn":["2073-8137","2073-8145"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical news of the North Caucasus","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.14300/mnnc.2026.21025","doi":"https://doi.org/10.14300/mnnc.2026.21025","is_oa":true,"landing_page_url":"https://doi.org/10.14300/mnnc.2026.21025","pdf_url":"https://medvestnik.stgmu.ru/files/articles/1658.pdf","source":{"id":"https://openalex.org/S4210168183","display_name":"Medical news of the North Caucasus","issn_l":"2073-8137","issn":["2073-8137","2073-8145"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical news of the North Caucasus","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7207567280.pdf","grobid_xml":"https://content.openalex.org/works/W7207567280.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2274492936","https://openalex.org/W2423021542","https://openalex.org/W2921434986","https://openalex.org/W2989909111","https://openalex.org/W2997868612","https://openalex.org/W3005410155","https://openalex.org/W3150599205","https://openalex.org/W4210243612","https://openalex.org/W4220666987","https://openalex.org/W4281664833","https://openalex.org/W4385739064","https://openalex.org/W4386359225","https://openalex.org/W4390437107","https://openalex.org/W4390984080","https://openalex.org/W4405681185","https://openalex.org/W4410730495","https://openalex.org/W4411048624","https://openalex.org/W4413949594","https://openalex.org/W4415071527","https://openalex.org/W4416587548"],"related_works":["https://openalex.org/W2371189527","https://openalex.org/W2358717789","https://openalex.org/W2112376569","https://openalex.org/W2088658584","https://openalex.org/W2112930606","https://openalex.org/W2380316513","https://openalex.org/W2055220513","https://openalex.org/W2115308669","https://openalex.org/W3029680462","https://openalex.org/W2385908632"],"abstract_inverted_index":{"\u041f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u0430":[0],"\u043e\u0446\u0435\u043d\u043a\u0430":[1,107],"\u043f\u0430\u0442\u043e\u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0445":[2],"\u043c\u0435\u0445\u0430\u043d\u0438\u0437\u043c\u043e\u0432":[3],"\u043a\u043e\u043b\u043e\u0440\u0435\u043a\u0442\u0430\u043b\u044c\u043d\u043e\u0433\u043e":[4],"\u0440\u0430\u043a\u0430":[5],"(\u041a\u0420\u0420)":[6],"\u0441":[7,34,64,102,113],"\u043f\u043e\u0437\u0438\u0446\u0438\u0439":[8],"\u0430\u043d\u0430\u043b\u0438\u0437\u0430":[9],"\u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438":[10],"\u0430\u043d\u0433\u0438\u043e\u0433\u0435\u043d\u043d\u044b\u0445":[11,108],"\u0444\u0430\u043a\u0442\u043e\u0440\u043e\u0432":[12],"\u043c\u0438\u043a\u0440\u043e\u043e\u043a\u0440\u0443\u0436\u0435\u043d\u0438\u044f":[13],"\u043e\u043f\u0443\u0445\u043e\u043b\u0438.\u0412\u044b\u043f\u043e\u043b\u043d\u0435\u043d\u043e":[14],"\u0433\u0438\u0441\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0435,":[15],"\u0430":[16],"\u0442\u0430\u043a\u0436\u0435":[17],"\u0438\u043c\u043c\u0443\u043d\u043e\u0433\u0438\u0441\u0442\u043e\u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0435":[18],"\u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435":[19],"\u0443\u0440\u043e\u0432\u043d\u044f":[20],"\u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u0438":[21,57,71,87],"HIF1a,":[22],"VEGF-A,":[23],"ANG1,":[24],"ANG2,":[25],"TIE2":[26,88],"\u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u043e\u0432":[27],"\u0444\u0440\u0430\u0433\u043c\u0435\u043d\u0442\u043e\u0432":[28],"\u0442\u043a\u0430\u043d\u0435\u0439":[29],"\u043e\u043f\u0443\u0445\u043e\u043b\u0438":[30,43],"\u0443":[31],"263":[32],"\u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432":[33,63,79],"\u043c\u043e\u0440\u0444\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438":[35],"\u0432\u0435\u0440\u0438\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u043c":[36],"\u041a\u0420\u0420.\u041e\u0446\u0435\u043d\u043a\u0430":[37],"\u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432":[38],"\u043f\u043e\u0437\u0432\u043e\u043b\u0438\u043b\u0430":[39],"\u043e\u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0437\u043e\u0432\u0430\u0442\u044c":[40],"\u0442\u0440\u0438":[41],"\u0438\u043c\u043c\u0443\u043d\u043e\u0444\u0435\u043d\u043e\u0442\u0438\u043f\u0430":[42],"\u0432":[44,61],"\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e\u0441\u0442\u0438":[45],"\u043e\u0442":[46,74,91],"\u0441\u0442\u0435\u043f\u0435\u043d\u0438":[47,75,104],"\u0432\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u0438":[48],"\u043e\u043f\u0443\u0445\u043e\u043b\u044c-\u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0439":[49],"\u0438\u043d\u0444\u0438\u043b\u044c\u0442\u0440\u0430\u0446\u0438\u0438:":[50],"\u00ab\u0445\u043e\u043b\u043e\u0434\u043d\u044b\u0439\u00bb,":[51],"\u00ab\u043f\u0440\u043e\u043c\u0435\u0436\u0443\u0442\u043e\u0447\u043d\u044b\u0439\u00bb,":[52],"\u00ab\u0433\u043e\u0440\u044f\u0447\u0438\u0439\u00bb.\u0412\u044b\u044f\u0432\u043b\u0435\u043d\u043e":[53],"\u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438":[54],"\u0437\u043d\u0430\u0447\u0438\u043c\u043e\u0435":[55],"\u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435":[56],"HIF1a":[58],"\u0438":[59,69,85,94,124],"VEGF-A":[60,73],"\u0433\u0440\u0443\u043f\u043f\u0435":[62],"\u043c\u0435\u0442\u0430\u0441\u0442\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u043c":[65],"\u043a\u043e\u043b\u043e\u0440\u0435\u043a\u0442\u0430\u043b\u044c\u043d\u044b\u043c":[66],"\u0440\u0430\u043a\u043e\u043c":[67],"(\u043c\u041a\u0420\u0420)":[68],"\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e\u0441\u0442\u044c":[70],"HIF1\u0430,":[72],"\u0438\u043d\u0444\u0438\u043b\u044c\u0442\u0440\u0430\u0446\u0438\u0438.\u0412":[76],"\u043e\u0431\u0435\u0438\u0445":[77],"\u0433\u0440\u0443\u043f\u043f\u0430\u0445":[78],"\u0443\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0430":[80],"\u0432\u044b\u0441\u043e\u043a\u0430\u044f":[81],"\u0441\u0442\u0435\u043f\u0435\u043d\u044c":[82],"\u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0441\u0442\u0438":[83],"ANG1":[84],"ANG2.\u0412\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u044c":[86],"\u0432\u0430\u0440\u044c\u0438\u0440\u043e\u0432\u0430\u043b\u0430\u0441\u044c":[89],"\u043d\u0435\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e":[90],"\u0441\u0442\u0430\u0442\u0443\u0441\u0430":[92],"\u0430\u043d\u0433\u0438\u043e\u043f\u043e\u044d\u0442\u0438\u043d\u043e\u0432":[93],"\u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0439":[95],"\u043c\u0430\u043d\u0438\u0444\u0435\u0441\u0442\u0430\u0446\u0438\u0438":[96],"\u043e\u043f\u0443\u0445\u043e\u043b\u0438,":[97],"\u043e\u0434\u043d\u0430\u043a\u043e":[98],"\u0431\u044b\u043b\u0430":[99],"\u0431\u043e\u043b\u0435\u0435":[100],"\u0441\u043e\u043f\u043e\u0441\u0442\u0430\u0432\u0438\u043c\u0430":[101],"\u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044f\u043c\u0438":[103],"\u0438\u043d\u0444\u0438\u043b\u044c\u0442\u0440\u0430\u0446\u0438\u0438":[105],"\u043e\u043f\u0443\u0445\u043e\u043b\u0438.\u0418\u043c\u043c\u0443\u043d\u043e\u0433\u0438\u0441\u0442\u043e\u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0430\u044f":[106],"\u0444\u0430\u043a\u0442\u043e\u0440\u043e\u0432,":[109],"\u0430\u043d\u0430\u043b\u0438\u0437":[110],"\u0438\u0445":[111],"\u0432\u0437\u0430\u0438\u043c\u043e\u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0439":[112],"\u043f\u0430\u0440\u0430\u043c\u0435\u0442\u0440\u0430\u043c\u0438":[114],"\u043e\u043f\u0443\u0445\u043e\u043b\u0435\u0432\u043e\u0439":[115],"\u0442\u0440\u0430\u043d\u0441\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u0438":[116],"\u0434\u043e\u043b\u0436\u043d\u044b":[117],"\u0441\u0442\u0430\u0442\u044c":[118],"\u0440\u0443\u0442\u0438\u043d\u043d\u043e\u0439":[119],"\u043f\u0440\u0430\u043a\u0442\u0438\u043a\u043e\u0439":[120],"\u0434\u043b\u044f":[121],"\u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f":[122],"\u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438":[123],"\u043f\u0435\u0440\u0441\u043e\u043d\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u0438":[125],"\u043d\u0430\u0437\u043d\u0430\u0447\u0430\u0435\u043c\u044b\u0445":[126],"\u0441\u0445\u0435\u043c":[127],"\u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0439":[128],"\u0442\u0435\u0440\u0430\u043f\u0438\u0438.":[129]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-09-04T00:00:00"}