{"id":"https://openalex.org/W7205046558","doi":null,"title":"Isolation, purification and chemical diversity of cryptophycin analogues","display_name":"Isolation, purification and chemical diversity of cryptophycin analogues","publication_year":2025,"publication_date":"2025-07-07","ids":{"openalex":"https://openalex.org/W7205046558"},"language":"en","primary_location":{"id":"pmh:oai:HAL:hal-05303730v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05303730v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"4\u00e8me Symposium International AFERP-STOLON, Jul 2025, Bordeaux, France","raw_type":"info:eu-repo/semantics/conferenceObject"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hal.science/hal-05303730v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081013093","display_name":"Thomas Gaslonde","orcid":"https://orcid.org/0000-0002-0262-746X","observed_orcids":["https://orcid.org/0000-0002-0262-746X"]},"institutions":[{"id":"https://openalex.org/I4403386520","display_name":"Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments","ror":"https://ror.org/05cbrk226","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4403386520"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gaslonde, Thomas","raw_affiliation_strings":["CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)","institution_ids":["https://openalex.org/I4403386520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081681394","display_name":"Vincent Jactel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4403386520","display_name":"Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments","ror":"https://ror.org/05cbrk226","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4403386520"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jactel, Vincent","raw_affiliation_strings":["CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)","institution_ids":["https://openalex.org/I4403386520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041663210","display_name":"Olivier Ploux","orcid":"https://orcid.org/0000-0003-2239-3987","observed_orcids":["https://orcid.org/0000-0003-2239-3987"]},"institutions":[{"id":"https://openalex.org/I4210094488","display_name":"Laboratoire Interdisciplinaire des \u00c9nergies de Demain","ror":"https://ror.org/00m43ek07","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210094488","https://openalex.org/I4210150854"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ploux, Olivier","raw_affiliation_strings":["LIED (UMR_8236) - Laboratoire Interdisciplinaire des Energies de Demain (11 rue Alice Domon et L\u00e9onie Duquet, B\u00e2t. Condorcet, case postale 7040, 75205 Paris cedex 13 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LIED (UMR_8236) - Laboratoire Interdisciplinaire des Energies de Demain (11 rue Alice Domon et L\u00e9onie Duquet, B\u00e2t. Condorcet, case postale 7040, 75205 Paris cedex 13 - France)","institution_ids":["https://openalex.org/I4210094488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046014201","display_name":"Annick M\u00e9jean","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094488","display_name":"Laboratoire Interdisciplinaire des \u00c9nergies de Demain","ror":"https://ror.org/00m43ek07","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210094488","https://openalex.org/I4210150854"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M\u00e9jean, Annick","raw_affiliation_strings":["LIED (UMR_8236) - Laboratoire Interdisciplinaire des Energies de Demain (11 rue Alice Domon et L\u00e9onie Duquet, B\u00e2t. Condorcet, case postale 7040, 75205 Paris cedex 13 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LIED (UMR_8236) - Laboratoire Interdisciplinaire des Energies de Demain (11 rue Alice Domon et L\u00e9onie Duquet, B\u00e2t. Condorcet, case postale 7040, 75205 Paris cedex 13 - France)","institution_ids":["https://openalex.org/I4210094488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055177972","display_name":"Luc Demange","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4403386520","display_name":"Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments","ror":"https://ror.org/05cbrk226","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4403386520"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Demange, Luc","raw_affiliation_strings":["CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)","institution_ids":["https://openalex.org/I4403386520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006548875","display_name":"Diana Lamaa","orcid":"https://orcid.org/0000-0002-2341-4666","observed_orcids":["https://orcid.org/0000-0002-2341-4666"]},"institutions":[{"id":"https://openalex.org/I4403386520","display_name":"Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments","ror":"https://ror.org/05cbrk226","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4403386520"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lamaa, Diana","raw_affiliation_strings":["CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)","institution_ids":["https://openalex.org/I4403386520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023133866","display_name":"Catherine Dupr\u00e9","orcid":"https://orcid.org/0000-0001-7639-2205","observed_orcids":["https://orcid.org/0000-0001-7639-2205"]},"institutions":[{"id":"https://openalex.org/I4210148006","display_name":"Laboratoire de G\u00e9nie des Proc\u00e9d\u00e9s \u2013 Environnement \u2013 Agro-alimentaire","ror":"https://ror.org/05ngxmx20","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I205703379","https://openalex.org/I2802204017","https://openalex.org/I4210088668","https://openalex.org/I4210095849","https://openalex.org/I4210127572","https://openalex.org/I4210148006","https://openalex.org/I4210157468","https://openalex.org/I49451733","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I97188460","display_name":"Nantes Universit\u00e9","ror":"https://ror.org/03gnr7b55","country_code":"FR","type":"education","lineage":["https://openalex.org/I97188460"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Dupre, Catherine","raw_affiliation_strings":["GEPEA - Laboratoire de g\u00e9nie des proc\u00e9d\u00e9s - environnement - agroalimentaire (France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GEPEA - Laboratoire de g\u00e9nie des proc\u00e9d\u00e9s - environnement - agroalimentaire (France)","institution_ids":["https://openalex.org/I4210148006","https://openalex.org/I97188460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092825202","display_name":"Mariem Ben Hammouda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ben Hammouda, Mariem","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014013404","display_name":"Dominique Grizeau","orcid":"https://orcid.org/0000-0003-3128-6673","observed_orcids":["https://orcid.org/0000-0003-3128-6673"]},"institutions":[{"id":"https://openalex.org/I4210148006","display_name":"Laboratoire de G\u00e9nie des Proc\u00e9d\u00e9s \u2013 Environnement \u2013 Agro-alimentaire","ror":"https://ror.org/05ngxmx20","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I205703379","https://openalex.org/I2802204017","https://openalex.org/I4210088668","https://openalex.org/I4210095849","https://openalex.org/I4210127572","https://openalex.org/I4210148006","https://openalex.org/I4210157468","https://openalex.org/I49451733","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I97188460","display_name":"Nantes Universit\u00e9","ror":"https://ror.org/03gnr7b55","country_code":"FR","type":"education","lineage":["https://openalex.org/I97188460"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Grizeau, Dominique","raw_affiliation_strings":["GEPEA - Laboratoire de g\u00e9nie des proc\u00e9d\u00e9s - environnement - agroalimentaire (France)","GEPEA-BAM - Bioproc\u00e9d\u00e9s Appliqu\u00e9s aux Microalgues (France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GEPEA - Laboratoire de g\u00e9nie des proc\u00e9d\u00e9s - environnement - agroalimentaire (France)","institution_ids":["https://openalex.org/I4210148006","https://openalex.org/I97188460"]},{"raw_affiliation_string":"GEPEA-BAM - Bioproc\u00e9d\u00e9s Appliqu\u00e9s aux Microalgues (France)","institution_ids":["https://openalex.org/I4210148006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023482042","display_name":"Jack Legrand","orcid":"https://orcid.org/0000-0001-9028-7575","observed_orcids":["https://orcid.org/0000-0001-9028-7575"]},"institutions":[{"id":"https://openalex.org/I4210148006","display_name":"Laboratoire de G\u00e9nie des Proc\u00e9d\u00e9s \u2013 Environnement \u2013 Agro-alimentaire","ror":"https://ror.org/05ngxmx20","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I205703379","https://openalex.org/I2802204017","https://openalex.org/I4210088668","https://openalex.org/I4210095849","https://openalex.org/I4210127572","https://openalex.org/I4210148006","https://openalex.org/I4210157468","https://openalex.org/I49451733","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I97188460","display_name":"Nantes Universit\u00e9","ror":"https://ror.org/03gnr7b55","country_code":"FR","type":"education","lineage":["https://openalex.org/I97188460"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Legrand, Jack","raw_affiliation_strings":["GEPEA - Laboratoire de g\u00e9nie des proc\u00e9d\u00e9s - environnement - agroalimentaire (France)","GEPEA-BAM - Bioproc\u00e9d\u00e9s Appliqu\u00e9s aux Microalgues (France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GEPEA - Laboratoire de g\u00e9nie des proc\u00e9d\u00e9s - environnement - agroalimentaire (France)","institution_ids":["https://openalex.org/I4210148006","https://openalex.org/I97188460"]},{"raw_affiliation_string":"GEPEA-BAM - Bioproc\u00e9d\u00e9s Appliqu\u00e9s aux Microalgues (France)","institution_ids":["https://openalex.org/I4210148006"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090888719","display_name":"Xavier Cachet","orcid":"https://orcid.org/0000-0001-9150-1932","observed_orcids":["https://orcid.org/0000-0001-9150-1932"]},"institutions":[{"id":"https://openalex.org/I4403386520","display_name":"Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments","ror":"https://ror.org/05cbrk226","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4403386520"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cachet, Xavier","raw_affiliation_strings":["CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CiTCoM - UMR 8038 - Cibles Th\u00e9rapeutiques et conception de m\u00e9dicaments (Facult\u00e9 de pharmacie 4 avenue de l'Observatoire 75006 PARIS - France)","institution_ids":["https://openalex.org/I4403386520"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12530","display_name":"Bioactive Natural Diterpenoids Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11340","display_name":"Marine Sponges and Natural Products","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryptophycin","display_name":"cryptophycin","score":0.7239999771118164},{"id":"https://openalex.org/keywords/natural-product-isolation","display_name":"natural product isolation","score":0.7319999933242798},{"id":"https://openalex.org/keywords/purification","display_name":"purification","score":0.5830000042915344},{"id":"https://openalex.org/keywords/chemical-diversity","display_name":"chemical diversity","score":0.9409999847412109},{"id":"https://openalex.org/keywords/macrolide-antibiotics","display_name":"macrolide antibiotics","score":0.49300000071525574},{"id":"https://openalex.org/keywords/streptomyces","display_name":"Streptomyces","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5672000050544739},{"id":"https://openalex.org/C2781316041","wikidata":"https://www.wikidata.org/wiki/Q1230584","display_name":"Diversity (politics)","level":2,"score":0.49390000104904175},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.35040000081062317},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29409998655319214},{"id":"https://openalex.org/C175528265","wikidata":"https://www.wikidata.org/wiki/Q500256","display_name":"Chemical structure","level":2,"score":0.2833000123500824},{"id":"https://openalex.org/C168831097","wikidata":"https://www.wikidata.org/wiki/Q413248","display_name":"Depsipeptide","level":2,"score":0.2824000120162964},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26170000433921814},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.25189998745918274},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.22349999845027924},{"id":"https://openalex.org/C2988562018","wikidata":"https://www.wikidata.org/wiki/Q1063","display_name":"Biological evolution","level":2,"score":0.22100000083446503}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:HAL:hal-05303730v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05303730v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"4\u00e8me Symposium International AFERP-STOLON, Jul 2025, Bordeaux, France","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":{"id":"pmh:oai:HAL:hal-05303730v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05303730v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"4\u00e8me Symposium International AFERP-STOLON, Jul 2025, Bordeaux, France","raw_type":"info:eu-repo/semantics/conferenceObject"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4401057627","https://openalex.org/W2049673480","https://openalex.org/W2952650702","https://openalex.org/W4398760591","https://openalex.org/W2914038622","https://openalex.org/W7205956545","https://openalex.org/W2952833643","https://openalex.org/W2019701027","https://openalex.org/W2888160738","https://openalex.org/W2077864732"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-09-02T00:00:00"}