{"id":"https://openalex.org/W7204998501","doi":"https://doi.org/10.64465/jkfn.v2i3.128","title":"Formulasi Dan Uji Iritasi Sediaan Gel Ekstrak Buah Senduduk Bulu (Miconia crenata (Vahl) Michelang Pada Kelinci Jantan (Oryctolagus cuniculus)","display_name":"Formulasi Dan Uji Iritasi Sediaan Gel Ekstrak Buah Senduduk Bulu (Miconia crenata (Vahl) Michelang Pada Kelinci Jantan (Oryctolagus cuniculus)","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7204998501","doi":"https://doi.org/10.64465/jkfn.v2i3.128"},"language":"id","primary_location":{"id":"doi:10.64465/jkfn.v2i3.128","doi":"https://doi.org/10.64465/jkfn.v2i3.128","is_oa":true,"landing_page_url":"https://doi.org/10.64465/jkfn.v2i3.128","pdf_url":"https://journal.marapublisher.com/index.php/jkfn/article/download/128/83","source":{"id":"https://openalex.org/S5407050404","display_name":"Jurnal Kesehatan Farmasi Nusantara","issn_l":"3109-0613","issn":["3109-0613","3109-2365"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jurnal Kesehatan Farmasi Nusantara","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://journal.marapublisher.com/index.php/jkfn/article/download/128/83","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5116632782","display_name":"Muhamad Deni Saputra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405276125","display_name":"Sekolah Tinggi Kesehatan Al-Fatah Bengkulu","ror":"https://ror.org/04w3vyj38","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405276125"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Muhamad Deni Saputra","raw_affiliation_strings":["Sekolah Tinggi Kesehatan Alfatah Bengkulu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sekolah Tinggi Kesehatan Alfatah Bengkulu","institution_ids":["https://openalex.org/I4405276125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045706262","display_name":"Luky Dharmayanti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luky Dharmayanti","raw_affiliation_strings":["STIKES Al-Fatah Bengkulu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"STIKES Al-Fatah Bengkulu","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082730247","display_name":"Dewi Winni Fauziah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dewi Winni Fauziah","raw_affiliation_strings":["STIKES Al-Fatah Bengkulu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"STIKES Al-Fatah Bengkulu","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041239408","display_name":"Nurwani Purnama Aji","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nurwani Purnama Aji","raw_affiliation_strings":["STIKES Al-Fatah Bengkulu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"STIKES Al-Fatah Bengkulu","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"3","first_page":"144","last_page":"155"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.5181000232696533,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.5181000232696533,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.29319998621940613,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.1046999990940094,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/miconia-crenata","display_name":"Miconia crenata","score":0.996999979019165},{"id":"https://openalex.org/keywords/topical-gel-formulation","display_name":"topical gel formulation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/skin-irritation","display_name":"skin irritation","score":0.7289999723434448},{"id":"https://openalex.org/keywords/secondary-metabolites","display_name":"secondary metabolites","score":0.6449999809265137},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9330000281333923},{"id":"https://openalex.org/keywords/topical-preparations","display_name":"topical formulation","score":0.3190000057220459},{"id":"https://openalex.org/keywords/extraction-yield","display_name":"extraction yield","score":0.5550000071525574},{"id":"https://openalex.org/keywords/gel-physical-properties","display_name":"gel physical properties","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.656000018119812},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.6212000250816345},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.36070001125335693},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.18629999458789825},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18610000610351562},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17970000207424164},{"id":"https://openalex.org/C3018223157","wikidata":"https://www.wikidata.org/wiki/Q7233257","display_name":"Positive control","level":2,"score":0.1785999983549118},{"id":"https://openalex.org/C2777228702","wikidata":"https://www.wikidata.org/wiki/Q5057534","display_name":"Celastrol","level":3,"score":0.1770000010728836},{"id":"https://openalex.org/C3019361144","wikidata":"https://www.wikidata.org/wiki/Q367359","display_name":"Negative control","level":2,"score":0.17000000178813934},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16660000383853912}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64465/jkfn.v2i3.128","doi":"https://doi.org/10.64465/jkfn.v2i3.128","is_oa":true,"landing_page_url":"https://doi.org/10.64465/jkfn.v2i3.128","pdf_url":"https://journal.marapublisher.com/index.php/jkfn/article/download/128/83","source":{"id":"https://openalex.org/S5407050404","display_name":"Jurnal Kesehatan Farmasi Nusantara","issn_l":"3109-0613","issn":["3109-0613","3109-2365"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jurnal Kesehatan Farmasi Nusantara","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.64465/jkfn.v2i3.128","doi":"https://doi.org/10.64465/jkfn.v2i3.128","is_oa":true,"landing_page_url":"https://doi.org/10.64465/jkfn.v2i3.128","pdf_url":"https://journal.marapublisher.com/index.php/jkfn/article/download/128/83","source":{"id":"https://openalex.org/S5407050404","display_name":"Jurnal Kesehatan Farmasi Nusantara","issn_l":"3109-0613","issn":["3109-0613","3109-2365"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jurnal Kesehatan Farmasi Nusantara","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204998501.pdf","grobid_xml":"https://content.openalex.org/works/W7204998501.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W2946929274","https://openalex.org/W2985401680","https://openalex.org/W3189218263","https://openalex.org/W4285317154","https://openalex.org/W4312078879","https://openalex.org/W4415059411","https://openalex.org/W7133319341","https://openalex.org/W7156232302","https://openalex.org/W7204657890"],"related_works":["https://openalex.org/W7126138359","https://openalex.org/W7218300992","https://openalex.org/W4378388141","https://openalex.org/W7053202656","https://openalex.org/W4318586499","https://openalex.org/W4410315210","https://openalex.org/W7095004317","https://openalex.org/W7126146135","https://openalex.org/W3119644555","https://openalex.org/W4367055942"],"abstract_inverted_index":{":":[0],"Buah":[1],"senduduk":[2,32,179],"bulu":[3,33,180],"(Miconia":[4],"crenata":[5],"(Vahl)":[6],"Michelang)":[7],"mengandung":[8],"metabolit":[9],"sekunder":[10],"seperti":[11],"flavonoid,":[12],"tanin,":[13],"saponin,":[14],"dan":[15,77,104,109,123,144,150],"fenolik":[16],"yang":[17,99],"berpotensi":[18,181],"dijadikan":[19],"bahan":[20,184],"aktif":[21,185],"pada":[22,43,106],"sediaan":[23,83],"topikal.":[24],"Penelitian":[25,46],"ini":[26],"bertujuan":[27],"untuk":[28,141],"memformulasi":[29],"ekstrak":[30,115,177],"buah":[31,178],"menjadi":[34,62,183],"gel":[35,186],"sekaligus":[36],"menilai":[37],"sifat":[38,85,163],"fisik":[39],"serta":[40,94,131],"tingkat":[41],"iritasi":[42,96,139,153,173],"kelinci":[44],"jantan.":[45],"bersifat":[47,121],"eksperimental":[48],"dengan":[49,69,74,79,133],"proses":[50],"ekstraksi":[51],"menggunakan":[52],"metode":[53],"maserasi":[54],"etanol":[55],"96":[56],"%.":[57,81,118],"Ekstrak":[58],"tersebut":[59],"kemudian":[60],"diformulasikan":[61],"empat":[63],"persiapan:":[64],"F0":[65],"tanpa":[66],"ekstrak,":[67],"F1":[68],"konsentrasi":[70],"4":[71],"%,":[72,76],"F2":[73],"6":[75],"F3":[78,145,157],"8":[80],"Penilaian":[82],"meliputi":[84],"organoleptik,":[86],"homogenitas,":[87],"pH,":[88,126],"daya":[89,91,127,129],"sebar,":[90,128],"lekat,":[92,130],"viskositas,":[93,132],"uji":[95],"akut":[97],"dermal":[98],"dipantau":[100],"melalui":[101],"munculnya":[102],"eritema":[103],"edema":[105],"24,":[107],"48,":[108],"72":[110],"jam.":[111],"Hasil":[112],"menunjukkan":[113],"rendemen":[114],"sebesar":[116,147],"12":[117],"Semua":[119],"formula":[120,160],"homogen":[122],"memenuhi":[124],"standar":[125],"rentang":[134],"pH":[135],"antara":[136],"5,11\u20135,87.":[137],"Indeks":[138],"primer":[140],"F1,":[142],"F2,":[143],"masing-masing":[146],"1,6;":[148],"1,8;":[149],"2,4,":[151],"menandakan":[152],"ringan":[154],"hingga":[155],"sedang.":[156,174],"dipilih":[158],"sebagai":[159],"terbaik":[161],"berdasarkan":[162],"fisiknya,":[164],"namun":[165],"penggunaannya":[166],"harus":[167],"mempertimbangkan":[168],"aspek":[169],"keamanan":[170,191],"karena":[171],"menimbulkan":[172],"Dengan":[175],"demikian,":[176],"dikembangkan":[182],"topikal,":[187],"meskipun":[188],"diperlukan":[189],"evaluasi":[190],"lebih":[192],"lanjut.":[193]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-02T00:00:00"}