{"id":"https://openalex.org/W7204926965","doi":"https://doi.org/10.1016/j.genrep.2026.102631","title":"Upregulation of RARA-AS1, a novel long noncoding RNA, is associated with thyroid cancer development","display_name":"Upregulation of RARA-AS1, a novel long noncoding RNA, is associated with thyroid cancer development","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7204926965","doi":"https://doi.org/10.1016/j.genrep.2026.102631"},"language":"en","primary_location":{"id":"doi:10.1016/j.genrep.2026.102631","doi":"https://doi.org/10.1016/j.genrep.2026.102631","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.genrep.2026.102631","pdf_url":null,"source":{"id":"https://openalex.org/S2765063225","display_name":"Gene Reports","issn_l":"2452-0144","issn":["2452-0144"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148866254","display_name":"Neda Lotfimanesh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neda Lotfimanesh","raw_affiliation_strings":["Department of Biological Science, Faculty of Basic Science, Higher Education Institute of Rab-Rashid, Tabriz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Science, Faculty of Basic Science, Higher Education Institute of Rab-Rashid, Tabriz, Iran","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041788383","display_name":"AmirHossein Yari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163205636","display_name":"Tabriz University of Medical Sciences","ror":"https://ror.org/04krpx645","country_code":"IR","type":"education","lineage":["https://openalex.org/I163205636"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Amirhossein Yari","raw_affiliation_strings":["Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran","institution_ids":["https://openalex.org/I163205636"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098536271","display_name":"Samin Abdolzadeh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163205636","display_name":"Tabriz University of Medical Sciences","ror":"https://ror.org/04krpx645","country_code":"IR","type":"education","lineage":["https://openalex.org/I163205636"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Samin Abdolzadeh","raw_affiliation_strings":["Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran","institution_ids":["https://openalex.org/I163205636"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091972651","display_name":"Omid Pourbagherian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163205636","display_name":"Tabriz University of Medical Sciences","ror":"https://ror.org/04krpx645","country_code":"IR","type":"education","lineage":["https://openalex.org/I163205636"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Omid Pourbagherian","raw_affiliation_strings":["Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran","institution_ids":["https://openalex.org/I163205636"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014884324","display_name":"Asiyeh Jebelli","orcid":"https://orcid.org/0000-0001-9494-2207","observed_orcids":["https://orcid.org/0000-0001-9494-2207"]},"institutions":[{"id":"https://openalex.org/I181744264","display_name":"Kharazmi University","ror":"https://ror.org/05hsgex59","country_code":"IR","type":"education","lineage":["https://openalex.org/I181744264"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Asiyeh Jebelli","raw_affiliation_strings":["Department of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran","institution_ids":["https://openalex.org/I181744264"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028112675","display_name":"Amir Ali Mokhtarzadeh","orcid":"https://orcid.org/0000-0002-4515-8675","observed_orcids":["https://orcid.org/0000-0002-4515-8675"]},"institutions":[{"id":"https://openalex.org/I163205636","display_name":"Tabriz University of Medical Sciences","ror":"https://ror.org/04krpx645","country_code":"IR","type":"education","lineage":["https://openalex.org/I163205636"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Amir Ali Mokhtarzadeh","raw_affiliation_strings":["Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran","institution_ids":["https://openalex.org/I163205636"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5028112675"],"corresponding_institution_ids":["https://openalex.org/I163205636"],"apc_list":{"value":2860,"currency":"USD","value_usd":2860},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"45","issue":null,"first_page":"102631","last_page":"102631"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.9750000238418579},{"id":"https://openalex.org/keywords/thyroid-cancer-diagnosis","display_name":"thyroid cancer diagnosis","score":0.5370000004768372},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.9049999713897705},{"id":"https://openalex.org/keywords/tgf-beta1","display_name":"TGF-\u03b21","score":0.7200000286102295},{"id":"https://openalex.org/keywords/ras-mapk-pathway","display_name":"RAS/MAPK pathway","score":0.9599999785423279},{"id":"https://openalex.org/keywords/gene-co-expression","display_name":"gene co-expression","score":0.6159999966621399},{"id":"https://openalex.org/keywords/lncrna-upregulation","display_name":"lncRNA upregulation","score":0.6539999842643738},{"id":"https://openalex.org/keywords/sex-differences-in-gene-expression","display_name":"sex differences in gene expression","score":0.593999981880188}],"concepts":[{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.8611999750137329},{"id":"https://openalex.org/C2779761222","wikidata":"https://www.wikidata.org/wiki/Q826522","display_name":"Thyroid cancer","level":3,"score":0.7218000292778015},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6360999941825867},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5223000049591064},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.44359999895095825},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.39399999380111694},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3714999854564667},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3203999996185303},{"id":"https://openalex.org/C2993294228","wikidata":"https://www.wikidata.org/wiki/Q13632630","display_name":"Thyroid carcinoma","level":3,"score":0.2603999972343445},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2475000023841858}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.genrep.2026.102631","doi":"https://doi.org/10.1016/j.genrep.2026.102631","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.genrep.2026.102631","pdf_url":null,"source":{"id":"https://openalex.org/S2765063225","display_name":"Gene Reports","issn_l":"2452-0144","issn":["2452-0144"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene Reports","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G8760800424","display_name":null,"funder_award_id":"79693","funder_id":"https://openalex.org/F4320322587","funder_display_name":"Tabriz University of Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320322587","display_name":"Tabriz University of Medical Sciences","ror":"https://ror.org/04krpx645"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1965874852","https://openalex.org/W1994811935","https://openalex.org/W2037345997","https://openalex.org/W2040239915","https://openalex.org/W2051190668","https://openalex.org/W2063825189","https://openalex.org/W2139518879","https://openalex.org/W2146512944","https://openalex.org/W2152970345","https://openalex.org/W2156955613","https://openalex.org/W2230320310","https://openalex.org/W2323288618","https://openalex.org/W2417052817","https://openalex.org/W2464424134","https://openalex.org/W2482590614","https://openalex.org/W2489385611","https://openalex.org/W2611797465","https://openalex.org/W2623093356","https://openalex.org/W2735687500","https://openalex.org/W2736730167","https://openalex.org/W2751913252","https://openalex.org/W2769586158","https://openalex.org/W2792163167","https://openalex.org/W2809168015","https://openalex.org/W2916672200","https://openalex.org/W2932374721","https://openalex.org/W2936201524","https://openalex.org/W2986514862","https://openalex.org/W3007426880","https://openalex.org/W3032327121","https://openalex.org/W3158945110","https://openalex.org/W3161656085","https://openalex.org/W3173121445","https://openalex.org/W3194837073","https://openalex.org/W3201411400","https://openalex.org/W4206965224","https://openalex.org/W4394878514","https://openalex.org/W4406606646","https://openalex.org/W4410540111","https://openalex.org/W4411136936","https://openalex.org/W4413304637","https://openalex.org/W4413998771","https://openalex.org/W7127605532"],"related_works":["https://openalex.org/W2809168015","https://openalex.org/W14849116","https://openalex.org/W3189295740","https://openalex.org/W3031754716","https://openalex.org/W3029725844","https://openalex.org/W4413628340","https://openalex.org/W3031504567","https://openalex.org/W3000660886","https://openalex.org/W2346340577","https://openalex.org/W2965558747"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-09-02T00:00:00"}
