{"id":"https://openalex.org/W7204902007","doi":"https://doi.org/10.4103/otr.otr_13_26","title":"Giant Schwannoma of the Leg: Insights from a Rare Case Report","display_name":"Giant Schwannoma of the Leg: Insights from a Rare Case Report","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7204902007","doi":"https://doi.org/10.4103/otr.otr_13_26"},"language":"en","primary_location":{"id":"doi:10.4103/otr.otr_13_26","doi":"https://doi.org/10.4103/otr.otr_13_26","is_oa":true,"landing_page_url":"https://doi.org/10.4103/otr.otr_13_26","pdf_url":null,"source":{"id":"https://openalex.org/S5407047400","display_name":"Journal of Orthopaedic Trauma and Reconstruction","issn_l":"3050-5607","issn":["3050-5607","3050-5615"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Trauma and Reconstruction","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7204902007"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.4103/otr.otr_13_26","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148933291","display_name":"Avishi Jaiswal","orcid":"https://orcid.org/0009-0009-4494-4218","observed_orcids":["https://orcid.org/0009-0009-4494-4218"]},"institutions":[{"id":"https://openalex.org/I164861460","display_name":"Manipal Academy of Higher Education","ror":"https://ror.org/02xzytt36","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460"]},{"id":"https://openalex.org/I4387153400","display_name":"Kasturba Medical College, Mangalore","ror":"https://ror.org/048vk1h54","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I4387153400"]},{"id":"https://openalex.org/I76414455","display_name":"Kasturba Medical College, Manipal","ror":"https://ror.org/05hg48t65","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I76414455"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Avishi Jaiswal","raw_affiliation_strings":["Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India","institution_ids":["https://openalex.org/I164861460","https://openalex.org/I4387153400","https://openalex.org/I76414455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139959630","display_name":"Atmananda S. Hegde","orcid":"https://orcid.org/0000-0001-6893-4238","observed_orcids":["https://orcid.org/0000-0001-6893-4238"]},"institutions":[{"id":"https://openalex.org/I164861460","display_name":"Manipal Academy of Higher Education","ror":"https://ror.org/02xzytt36","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460"]},{"id":"https://openalex.org/I4387153400","display_name":"Kasturba Medical College, Mangalore","ror":"https://ror.org/048vk1h54","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I4387153400"]},{"id":"https://openalex.org/I76414455","display_name":"Kasturba Medical College, Manipal","ror":"https://ror.org/05hg48t65","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I76414455"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Atmananda S. Hegde","raw_affiliation_strings":["Department of Orthopaedics, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India","institution_ids":["https://openalex.org/I164861460","https://openalex.org/I4387153400","https://openalex.org/I76414455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012013258","display_name":"Pranav Rajasekharan","orcid":"https://orcid.org/0009-0005-9088-953X","observed_orcids":["https://orcid.org/0009-0005-9088-953X"]},"institutions":[{"id":"https://openalex.org/I164861460","display_name":"Manipal Academy of Higher Education","ror":"https://ror.org/02xzytt36","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460"]},{"id":"https://openalex.org/I4387153400","display_name":"Kasturba Medical College, Mangalore","ror":"https://ror.org/048vk1h54","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I4387153400"]},{"id":"https://openalex.org/I76414455","display_name":"Kasturba Medical College, Manipal","ror":"https://ror.org/05hg48t65","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I76414455"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pranav Rajasekharan","raw_affiliation_strings":["Department of Orthopaedics, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India","institution_ids":["https://openalex.org/I164861460","https://openalex.org/I4387153400","https://openalex.org/I76414455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003384521","display_name":"Rakshatha Nayak","orcid":"https://orcid.org/0000-0002-7257-1465","observed_orcids":["https://orcid.org/0000-0002-7257-1465"]},"institutions":[{"id":"https://openalex.org/I164861460","display_name":"Manipal Academy of Higher Education","ror":"https://ror.org/02xzytt36","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460"]},{"id":"https://openalex.org/I4387153400","display_name":"Kasturba Medical College, Mangalore","ror":"https://ror.org/048vk1h54","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I4387153400"]},{"id":"https://openalex.org/I76414455","display_name":"Kasturba Medical College, Manipal","ror":"https://ror.org/05hg48t65","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I76414455"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rakshatha Nayak","raw_affiliation_strings":["Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India","institution_ids":["https://openalex.org/I164861460","https://openalex.org/I4387153400","https://openalex.org/I76414455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5104196376","display_name":"Pratham Shetty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I164861460","display_name":"Manipal Academy of Higher Education","ror":"https://ror.org/02xzytt36","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460"]},{"id":"https://openalex.org/I4387153400","display_name":"Kasturba Medical College, Mangalore","ror":"https://ror.org/048vk1h54","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I4387153400"]},{"id":"https://openalex.org/I76414455","display_name":"Kasturba Medical College, Manipal","ror":"https://ror.org/05hg48t65","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460","https://openalex.org/I76414455"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pratham Shetty","raw_affiliation_strings":["Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India","institution_ids":["https://openalex.org/I164861460","https://openalex.org/I4387153400","https://openalex.org/I76414455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"1","first_page":"88","last_page":"92"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11173","display_name":"Neurofibromatosis and Schwannoma Cases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11173","display_name":"Neurofibromatosis and Schwannoma Cases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13363","display_name":"Soft tissue tumors and treatment","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/giant-schwannoma","display_name":"giant schwannoma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/peripheral-nerve-sheath-tumor","display_name":"peripheral nerve sheath tumor","score":0.890999972820282},{"id":"https://openalex.org/keywords/surgical-excision","display_name":"surgical excision","score":0.8930000066757202},{"id":"https://openalex.org/keywords/nerve-preservation","display_name":"nerve preservation","score":0.8330000042915344},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.7580000162124634},{"id":"https://openalex.org/keywords/benign-peripheral-nerve-tumor","display_name":"benign peripheral nerve tumor","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8543000221252441},{"id":"https://openalex.org/C2781447767","wikidata":"https://www.wikidata.org/wiki/Q369148","display_name":"Schwannoma","level":2,"score":0.8497999906539917},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6395999789237976},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5888000130653381},{"id":"https://openalex.org/C2780801072","wikidata":"https://www.wikidata.org/wiki/Q837512","display_name":"Differential diagnosis","level":2,"score":0.5209000110626221},{"id":"https://openalex.org/C136948725","wikidata":"https://www.wikidata.org/wiki/Q1458306","display_name":"Soft tissue","level":2,"score":0.46470001339912415},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4343000054359436},{"id":"https://openalex.org/C2778986146","wikidata":"https://www.wikidata.org/wiki/Q11590740","display_name":"Nerve sheath tumor","level":3,"score":0.4074000120162964},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.399399995803833},{"id":"https://openalex.org/C2993790278","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Nerve sheath","level":3,"score":0.3971000015735626},{"id":"https://openalex.org/C2909382536","wikidata":"https://www.wikidata.org/wiki/Q369148","display_name":"Neurilemoma","level":3,"score":0.3926999866962433},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.38260000944137573},{"id":"https://openalex.org/C77076574","wikidata":"https://www.wikidata.org/wiki/Q2152526","display_name":"Giant cell","level":2,"score":0.36059999465942383},{"id":"https://openalex.org/C2776825438","wikidata":"https://www.wikidata.org/wiki/Q1978198","display_name":"Tibial nerve","level":3,"score":0.3352000117301941},{"id":"https://openalex.org/C3020063470","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgical excision","level":2,"score":0.32499998807907104},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.3082999885082245},{"id":"https://openalex.org/C2908810772","wikidata":"https://www.wikidata.org/wiki/Q15979047","display_name":"Giant Cell Tumors","level":3,"score":0.29919999837875366},{"id":"https://openalex.org/C3020547009","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathological examination","level":2,"score":0.2937000095844269},{"id":"https://openalex.org/C527108885","wikidata":"https://www.wikidata.org/wiki/Q835153","display_name":"Physical examination","level":2,"score":0.2890999913215637},{"id":"https://openalex.org/C529618451","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonography","level":2,"score":0.2721000015735626},{"id":"https://openalex.org/C2910357046","wikidata":"https://www.wikidata.org/wiki/Q11590740","display_name":"Nerve sheath neoplasm","level":4,"score":0.2687999904155731},{"id":"https://openalex.org/C2781105203","wikidata":"https://www.wikidata.org/wiki/Q1417240","display_name":"Benign tumor","level":2,"score":0.26089999079704285},{"id":"https://openalex.org/C2776660947","wikidata":"https://www.wikidata.org/wiki/Q841423","display_name":"Upper limb","level":2,"score":0.2531999945640564}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4103/otr.otr_13_26","doi":"https://doi.org/10.4103/otr.otr_13_26","is_oa":true,"landing_page_url":"https://doi.org/10.4103/otr.otr_13_26","pdf_url":null,"source":{"id":"https://openalex.org/S5407047400","display_name":"Journal of Orthopaedic Trauma and Reconstruction","issn_l":"3050-5607","issn":["3050-5607","3050-5615"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Trauma and Reconstruction","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.4103/otr.otr_13_26","doi":"https://doi.org/10.4103/otr.otr_13_26","is_oa":true,"landing_page_url":"https://doi.org/10.4103/otr.otr_13_26","pdf_url":null,"source":{"id":"https://openalex.org/S5407047400","display_name":"Journal of Orthopaedic Trauma and Reconstruction","issn_l":"3050-5607","issn":["3050-5607","3050-5615"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Trauma and Reconstruction","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1931616438","https://openalex.org/W2005835110","https://openalex.org/W2006603447","https://openalex.org/W2022265089","https://openalex.org/W2045561250","https://openalex.org/W2077120900","https://openalex.org/W2159664581","https://openalex.org/W2327422721","https://openalex.org/W4327589014","https://openalex.org/W4383197296"],"related_works":["https://openalex.org/W4383197296","https://openalex.org/W2046979076","https://openalex.org/W4400120658","https://openalex.org/W2774541427","https://openalex.org/W2889717846","https://openalex.org/W7161574542","https://openalex.org/W2888126529","https://openalex.org/W2620004993","https://openalex.org/W7151555963","https://openalex.org/W4414652533"],"abstract_inverted_index":{"Abstract":[0],"Schwannomas":[1],"are":[2,40,143],"rare,":[3],"slow-growing":[4,176],"benign":[5,89,190],"tumors":[6],"arising":[7,97,200],"from":[8,98,201],"Schwann":[9],"cells":[10],"of":[11,34,64,73,102,127,132,139,164,180,206,248],"the":[12,19,70,74,103,140,181,207],"peripheral":[13],"nerve":[14,150,204,210],"sheath.":[15],"They":[16],"predominantly":[17],"affect":[18],"head,":[20],"neck,":[21],"and":[22,45,78,119,228,233,245],"upper":[23],"extremities;":[24],"lower":[25,141,182],"limb":[26,142],"involvement":[27],"is":[28],"uncommon,":[29],"occurring":[30],"in":[31,171],"approximately":[32],"1%":[33],"cases.":[35],"Tumors":[36],"exceeding":[37],"5":[38],"cm":[39],"classified":[41],"as":[42,167],"giant":[43,111,165,198],"schwannomas":[44,138],"carry":[46],"an":[47,211],"even":[48,156],"more":[49],"unusual":[50],"clinical":[51],"profile.":[52],"We":[53],"report":[54],"a":[55,61,84,94,99,110,168,188,197,202],"60-year-old":[56],"male":[57],"who":[58],"presented":[59],"with":[60,88,129,148,174,237],"10-year":[62],"history":[63],"insidious,":[65],"gradually":[66],"enlarging":[67],"swelling":[68],"over":[69],"anterolateral":[71],"aspect":[72],"left":[75],"leg.":[76],"Ultrasonography":[77],"magnetic":[79],"resonance":[80],"imaging":[81,186],"(MRI)":[82],"identified":[83],"well-encapsulated":[85,95],"intermuscular":[86,191],"lesion":[87],"characteristics.":[90],"Surgical":[91],"excision":[92,240],"revealed":[93],"growth":[96],"muscular":[100],"branch":[101,205],"anterior":[104,208],"tibial":[105,209],"nerve.":[106],"Histopathological":[107],"examination":[108],"confirmed":[109],"schwannoma.":[112],"The":[113],"patient":[114],"achieved":[115],"complete":[116,238],"symptomatic":[117],"relief":[118],"returned":[120],"to":[121],"normal":[122],"activities":[123],"within":[124],"3":[125],"weeks":[126],"surgery,":[128],"no":[130,246],"evidence":[131,247],"recurrence":[133,249],"at":[134,250],"6-month":[135],"follow-up.":[136],"Giant":[137],"rare.":[144],"Meticulous":[145],"surgical":[146,239],"excision,":[147],"maximal":[149],"preservation,":[151],"yields":[152],"excellent":[153],"functional":[154,243],"outcomes":[155],"for":[157],"large":[158],"tumors.":[159],"Clinicians":[160],"should":[161],"maintain":[162],"awareness":[163],"schwannoma":[166,199],"differential":[169],"diagnosis":[170],"patients":[172],"presenting":[173],"long-standing,":[175],"soft":[177],"tissue":[178],"swellings":[179],"limb,":[183],"particularly":[184],"when":[185],"suggests":[187],"well-encapsulated,":[189],"lesion.":[192],"This":[193],"case":[194],"highlights":[195],"that":[196,255],"motor":[203],"exceptionally":[212],"rare":[213],"anatomical":[214],"location,":[215],"can":[216,222,234],"present":[217],"without":[218,230],"classical":[219],"neurological":[220],"symptoms,":[221],"be":[223,235],"reliably":[224],"characterized":[225],"by":[226],"ultrasound":[227],"MRI":[229],"pre-operative":[231],"biopsy,":[232],"treated":[236],"yielding":[241],"full":[242],"recovery":[244],"6":[251],"months,":[252],"thereby":[253],"demonstrating":[254],"tumor":[256],"size":[257],"alone":[258],"does":[259],"not":[260],"predict":[261],"poor":[262],"outcome.":[263]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2026-09-02T00:00:00"}