{"id":"https://openalex.org/W7204901641","doi":"https://doi.org/10.37609/akya.1135.c18810","title":"Gestasyonel Trofoblastik Hastal\u0131klar Tan\u0131 ve Tedavi","display_name":"Gestasyonel Trofoblastik Hastal\u0131klar Tan\u0131 ve Tedavi","publication_year":2022,"publication_date":"2022-03-02","ids":{"openalex":"https://openalex.org/W7204901641","doi":"https://doi.org/10.37609/akya.1135.c18810"},"language":"tr","primary_location":{"id":"doi:10.37609/akya.1135.c18810","doi":"https://doi.org/10.37609/akya.1135.c18810","is_oa":false,"landing_page_url":"https://doi.org/10.37609/akya.1135.c18810","pdf_url":null,"source":{"id":"https://openalex.org/S7407089364","display_name":"Akademisyen Kitabevi eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jinekolojik Onkolojide Bak\u0131m","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4318538023","display_name":"Jinekolojik Onkolojide Bak\u0131m"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046512264","display_name":"\u00d6zlem Ko\u015far Can","orcid":"https://orcid.org/0000-0001-7101-4838","observed_orcids":["https://orcid.org/0000-0001-7101-4838"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00d6zlem Ko\u015far Can","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5074150784","display_name":"Erkan Alata\u015f","orcid":"https://orcid.org/0000-0001-6423-5106","observed_orcids":["https://orcid.org/0000-0001-6423-5106"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erkan Alata\u015f","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.79163439,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"441","last_page":"464"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gestational-trophoblastic-disease","display_name":"gestational trophoblastic disease","score":0.9520000219345093},{"id":"https://openalex.org/keywords/hydatidiform-mole","display_name":"hydatidiform mole","score":0.9150000214576721},{"id":"https://openalex.org/keywords/invasive-mole","display_name":"invasive mole","score":0.8370000123977661},{"id":"https://openalex.org/keywords/choriocarcinoma","display_name":"choriocarcinoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/placental-site-trophoblastic-tumor","display_name":"placental site trophoblastic tumor","score":0.996999979019165},{"id":"https://openalex.org/keywords/epithelioid-trophoblastic-tumor","display_name":"epithelioid trophoblastic tumor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/human-chorionic-gonadotropin","display_name":"human chorionic gonadotropin","score":0.9629999995231628},{"id":"https://openalex.org/keywords/figo-staging","display_name":"FIGO staging","score":0.7300000190734863},{"id":"https://openalex.org/keywords/who-risk-score","display_name":"WHO risk score","score":0.7990000247955322},{"id":"https://openalex.org/keywords/ema-co-chemotherapy","display_name":"EMA-CO chemotherapy","score":0.8080000281333923},{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.7490000128746033},{"id":"https://openalex.org/keywords/dactinomycin","display_name":"actinomycin D","score":0.9959999918937683},{"id":"https://openalex.org/keywords/vacuum-aspiration","display_name":"vacuum aspiration","score":0.6259999871253967},{"id":"https://openalex.org/keywords/hysterectomy","display_name":"hysterectomy","score":0.9779999852180481}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5275999903678894},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.210999995470047},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.19939999282360077},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.18279999494552612},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.17880000174045563},{"id":"https://openalex.org/C12713177","wikidata":"https://www.wikidata.org/wiki/Q1900281","display_name":"Perspective (graphical)","level":2,"score":0.17489999532699585},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.17409999668598175},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.1720999926328659},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.17100000381469727},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.17059999704360962}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.37609/akya.1135.c18810","doi":"https://doi.org/10.37609/akya.1135.c18810","is_oa":false,"landing_page_url":"https://doi.org/10.37609/akya.1135.c18810","pdf_url":null,"source":{"id":"https://openalex.org/S7407089364","display_name":"Akademisyen Kitabevi eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jinekolojik Onkolojide Bak\u0131m","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7203532131","https://openalex.org/W7117579237","https://openalex.org/W4390332119","https://openalex.org/W7134907174","https://openalex.org/W2992630897","https://openalex.org/W4296754472","https://openalex.org/W2889161679","https://openalex.org/W4247802194","https://openalex.org/W3006684626","https://openalex.org/W4376565408"],"abstract_inverted_index":{"Gestasyonel":[0],"trofoblastik":[1,23,28,130],"hastal\u0131klar":[2],"(GTH),":[3],"plasentadan":[4],"kaynaklanan":[5],"ve":[6,14,26,62,71,101,137],"lokal":[7],"invazyon":[8],"ile":[9,74,158],"metastaz":[10],"yetene\u011fi":[11],"olan":[12],"komplet":[13],"parsiyel":[15],"hidatiform":[16],"mol,":[17,19],"invaziv":[18],"koryokarsinom,":[20],"plasental":[21],"site":[22,194],"t\u00fcm\u00f6r":[24,46],"(PSTT)":[25],"epiteloid":[27],"t\u00fcm\u00f6r\u00fc":[29],"(ETT)":[30],"i\u00e7eren":[31],"bir":[32],"hastal\u0131k":[33],"grubudur.":[34],"Gebelik":[35],"trofoblastlar\u0131n\u0131n":[36],"anormal":[37],"a\u015f\u0131r\u0131":[38,88],"proliferasyonu":[39],"sonucu":[40],"geli\u015fen":[41],"bu":[42],"hastal\u0131klar\u0131n":[43],"en":[44,53],"\u00f6nemli":[45],"belirteci":[47],"insan":[48],"koryonik":[49],"gonadotropinidir":[50],"(hCG).":[51],"Hastal\u0131klar\u0131n":[52],"yayg\u0131n":[54],"risk":[55,141,232,340],"fakt\u00f6rleri":[56],"aras\u0131nda":[57],"u\u00e7":[58],"anne":[59],"ya\u015flar\u0131":[60],"(\u226415":[61,244],">35),":[63,246],"ge\u00e7irilmi\u015f":[64],"molar":[65,250],"gebelik":[66],"\u00f6yk\u00fcs\u00fc,":[67],"yetersiz":[68],"hayvansal":[69],"besin":[70],"karoten":[72],"t\u00fcketimi":[73],"baz\u0131":[75],"genetik":[76],"mutasyonlar":[77],"yer":[78],"almaktad\u0131r.":[79],"Tan\u0131":[80],"s\u00fcrecinde":[81],"klinik":[82],"semptomlar\u0131n":[83],"(en":[84],"s\u0131k":[85],"vajinal":[86],"kanama,":[87],"uterin":[89],"b\u00fcy\u00fcme,":[90],"hiperemezis":[91],"gravidarum,":[92,281],"preeklampsi)":[93],"takibinin":[94],"yan\u0131":[95],"s\u0131ra":[96],"laboratuvar":[97],"testleri,":[98],"ultrasonografi,":[99],"Doppler":[100],"MRG":[102],"y\u00f6ntemlerinden":[103],"yararlan\u0131lmakta,":[104],"kesin":[105],"tan\u0131":[106],"ise":[107,123,134],"histopatolojik":[108],"incelemeyle":[109],"konulmaktad\u0131r.":[110],"Tedavide":[111],"do\u011furganl\u0131\u011f\u0131n\u0131":[112],"korumak":[113],"isteyen":[114],"hastalarda":[115,122],"\u00f6ncelikle":[116],"vakum":[117],"k\u00fcretaj,":[118],"\u00e7ocuk":[119],"istemini":[120],"tamamlam\u0131\u015f":[121],"histerektomi":[124],"tercih":[125],"edilmektedir.":[126],"K\u00f6t\u00fc":[127],"huylu":[128],"gestasyonel":[129],"neoplazi":[131],"(GTN)":[132,327],"vakalar\u0131":[133],"FIGO":[135,334],"evrelemesi":[136],"D\u00fcnya":[138],"Sa\u011fl\u0131k":[139],"\u00d6rg\u00fct\u00fc":[140],"skorlama":[142],"sistemine":[143],"g\u00f6re":[144],"s\u0131n\u0131fland\u0131r\u0131larak":[145],"tek":[146],"ajanl\u0131":[147],"(metotreksat":[148],"veya":[149],"aktinomisin":[150],"D)":[151,352],"ya":[152],"da":[153],"kombine":[154],"kemoterapi":[155],"protokolleri":[156],"(EMA-CO)":[157,357],"ba\u015far\u0131yla":[159],"tedavi":[160],"edilebilmektedir.":[161],"Gestational":[162],"trophoblastic":[163,195,200,325],"diseases":[164],"(GTD)":[165],"are":[166,291,329,344],"a":[167,220,247],"spectrum":[168],"of":[169,222,226,237,249,255],"disorders":[170,239],"originating":[171],"from":[172],"the":[173,177,209,223,235,265,294,333],"placenta":[174],"that":[175],"possess":[176],"capacity":[178],"for":[179,214,234,307,317],"local":[180],"invasion":[181],"and":[182,186,198,245,258,260,282,288,336,343],"metastasis,":[183],"encompassing":[184],"complete":[185],"partial":[187],"hydatidiform":[188],"moles,":[189,191],"invasive":[190],"choriocarcinoma,":[192],"placental":[193],"tumor":[196,201,212],"(PSTT),":[197],"epithelioid":[199],"(ETT).":[202],"Human":[203],"chorionic":[204],"gonadotropin":[205],"(hCG)":[206],"serves":[207],"as":[208,219,274],"most":[210,230],"critical":[211],"marker":[213],"these":[215,238],"diseases,":[216],"which":[217],"develop":[218],"result":[221],"abnormal":[224],"over-proliferation":[225],"pregnancy":[227],"trophoblasts.":[228],"The":[229],"prominent":[231],"factors":[233],"development":[236],"include":[240],"extreme":[241],"maternal":[242],"ages":[243],"history":[248],"pregnancy,":[251],"low":[252],"dietary":[253],"intake":[254],"animal":[256],"protein":[257],"carotene,":[259],"certain":[261],"genetic":[262],"mutations.":[263],"In":[264],"diagnostic":[266],"phase,":[267],"along":[268],"with":[269],"monitoring":[270],"clinical":[271],"symptoms":[272],"such":[273],"vaginal":[275],"bleeding,":[276],"excessive":[277],"uterine":[278],"enlargement,":[279],"hyperemesis":[280],"preeclampsia,":[283],"laboratory":[284],"tests,":[285],"ultrasonography,":[286],"Doppler,":[287],"MRI":[289],"methods":[290],"utilized,":[292],"while":[293],"definitive":[295],"diagnosis":[296],"is":[297,315],"established":[298],"through":[299],"histopathological":[300],"examination.":[301],"Treatment":[302],"primarily":[303],"involves":[304],"vacuum":[305],"curettage":[306],"patients":[308],"wishing":[309],"to":[310,332],"preserve":[311],"fertility,":[312],"whereas":[313],"hysterectomy":[314],"preferred":[316],"those":[318],"who":[319],"have":[320],"completed":[321],"childbearing.":[322],"Malignant":[323],"gestational":[324],"neoplasia":[326],"cases":[328],"classified":[330],"according":[331],"staging":[335],"World":[337],"Health":[338],"Organization":[339],"scoring":[341],"systems":[342],"successfully":[345],"managed":[346],"using":[347],"single-agent":[348],"(methotrexate":[349],"or":[350,353],"actinomycin":[351],"combination":[354],"chemotherapy":[355],"protocols":[356]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-09-02T00:00:00"}