{"id":"https://openalex.org/W7204853397","doi":"https://doi.org/10.5551/jat.66242","title":"The Waist-to-Height Ratio and Incidence of High LDL Cholesterol in Japanese: A Retrospective Cohort Study","display_name":"The Waist-to-Height Ratio and Incidence of High LDL Cholesterol in Japanese: A Retrospective Cohort Study","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7204853397","doi":"https://doi.org/10.5551/jat.66242","pmid":"https://pubmed.ncbi.nlm.nih.gov/42686582"},"language":"en","primary_location":{"id":"doi:10.5551/jat.66242","doi":"https://doi.org/10.5551/jat.66242","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.66242","pdf_url":"https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_66242/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_66242/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5122208982","display_name":"Takako Fujii","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takako Fujii","raw_affiliation_strings":["Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015372245","display_name":"Shintaro Ishida","orcid":"https://orcid.org/0000-0003-2257-1747","observed_orcids":["https://orcid.org/0000-0003-2257-1747"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shintaro Ishida","raw_affiliation_strings":["Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028564058","display_name":"Makiko Abe","orcid":"https://orcid.org/0000-0002-6793-8840","observed_orcids":["https://orcid.org/0000-0002-6793-8840"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makiko Abe","raw_affiliation_strings":["Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076880432","display_name":"Miki Kawazoe","orcid":"https://orcid.org/0000-0002-6569-9452","observed_orcids":["https://orcid.org/0000-0002-6569-9452"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Miki Kawazoe","raw_affiliation_strings":["Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134752616","display_name":"Toshiki Maeda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiki Maeda","raw_affiliation_strings":["Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025875009","display_name":"Chikara Yoshimura","orcid":"https://orcid.org/0000-0003-1639-8458","observed_orcids":["https://orcid.org/0000-0003-1639-8458"]},"institutions":[{"id":"https://openalex.org/I4210092114","display_name":"Fukuoka University Hospital","ror":"https://ror.org/00d3mr981","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210092114"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chikara Yoshimura","raw_affiliation_strings":["Sleep Medicine Center, Fukuoka University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep Medicine Center, Fukuoka University Hospital","institution_ids":["https://openalex.org/I4210092114"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049872554","display_name":"Yori Inoue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yori Inoue","raw_affiliation_strings":["Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071055536","display_name":"Kazuhiro Tada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuhiro Tada","raw_affiliation_strings":["Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137603414","display_name":"Koji Takahashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Takahashi","raw_affiliation_strings":["Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140270185","display_name":"Kenji Ito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Ito","raw_affiliation_strings":["Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020606674","display_name":"Kosuke Masutani","orcid":"https://orcid.org/0000-0001-9190-4600","observed_orcids":["https://orcid.org/0000-0001-9190-4600"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kosuke Masutani","raw_affiliation_strings":["Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086855818","display_name":"Hisatomi Arima","orcid":"https://orcid.org/0000-0002-2064-2014","observed_orcids":["https://orcid.org/0000-0002-2064-2014"]},"institutions":[{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisatomi Arima","raw_affiliation_strings":["Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University","institution_ids":["https://openalex.org/I31784960"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.68406332,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.5092999935150146,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.5092999935150146,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.482699990272522,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/waist-to-height-ratio","display_name":"waist-to-height ratio","score":0.996999979019165},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.7310000061988831},{"id":"https://openalex.org/keywords/abdominal-obesity","display_name":"abdominal obesity","score":0.7279999852180481},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.7540000081062317},{"id":"https://openalex.org/keywords/atherosclerotic-cardiovascular-disease","display_name":"atherosclerotic cardiovascular disease","score":0.8389999866485596},{"id":"https://openalex.org/keywords/anthropometric-markers","display_name":"anthropometric markers","score":0.6890000104904175},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.8109999895095825},{"id":"https://openalex.org/keywords/japanese-adults","display_name":"Japanese adults","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8870999813079834},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.7965999841690063},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.7483999729156494},{"id":"https://openalex.org/C3019550498","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Ldl cholesterol","level":3,"score":0.6672000288963318},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6629999876022339},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4846000075340271},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.459199994802475},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4514000117778778},{"id":"https://openalex.org/C2994423189","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Total cholesterol","level":3,"score":0.4410000145435333},{"id":"https://openalex.org/C2909983478","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglycerides blood","level":4,"score":0.3434000015258789},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.2766999900341034},{"id":"https://openalex.org/C2910980524","wikidata":"https://www.wikidata.org/wiki/Q954845","display_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","level":3,"score":0.27070000767707825},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2694999873638153},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.2621999979019165}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5551/jat.66242","doi":"https://doi.org/10.5551/jat.66242","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.66242","pdf_url":"https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_66242/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},{"id":"pmid:42686582","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42686582","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of atherosclerosis and thrombosis","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5551/jat.66242","doi":"https://doi.org/10.5551/jat.66242","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.66242","pdf_url":"https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_66242/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320323314","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204853397.pdf","grobid_xml":"https://content.openalex.org/works/W7204853397.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2128876496","https://openalex.org/W7095466407","https://openalex.org/W4247617269","https://openalex.org/W7202383674","https://openalex.org/W4412846980","https://openalex.org/W4415755527","https://openalex.org/W4409888134","https://openalex.org/W158841769","https://openalex.org/W3082331787","https://openalex.org/W2889965575"],"abstract_inverted_index":{"AIM:":[0],"Low-density":[1],"lipoprotein":[2],"cholesterol":[3],"(LDL-C)":[4],"is":[5],"a":[6,22,54,136,218,244],"major":[7],"contributor":[8],"to":[9,120,217],"atherosclerotic":[10],"cardiovascular":[11],"disease":[12],"(CVD).":[13],"The":[14,85],"waist-to-height":[15],"ratio":[16,157],"(WHtR)":[17],"has":[18],"been":[19],"proposed":[20],"as":[21,104],"practical":[23],"marker":[24],"of":[25,79,111,140,201,213,233],"central":[26],"obesity;":[27],"however,":[28],"evidence":[29],"linking":[30],"WHtR":[31,48,93,194,211,226,241],"with":[32,197,229],"incident":[33,202,234],"high":[34,100,149,203,235],"LDL-C":[35,51,101,105,150,204],"levels":[36],"in":[37,53,57,205,221],"Japanese":[38],"populations":[39],"remains":[40],"limited.":[41],"This":[42,60],"study":[43,63],"investigated":[44],"the":[45,75,122,154,178],"association":[46],"between":[47,89],"and":[49,81,91,131,145],"future":[50],"elevation":[52],"community-based":[55],"cohort":[56,62],"Japan.":[58],"METHODS:":[59],"retrospective":[61],"included":[64],"3,934":[65],"adults":[66],"aged":[67],"30-74":[68],"years":[69],"without":[70],"dyslipidemia":[71],"at":[72,251],"baseline":[73],"from":[74],"Iki":[76],"Epidemiological":[77],"Study":[78],"Atherosclerosis":[80],"Chronic":[82],"Kidney":[83],"Disease.":[84],"participants":[86],"were":[87,118],"followed":[88],"2008":[90],"2019.":[92],"was":[94,102,169,184,195,227],"categorized":[95],"into":[96],"sex-specific":[97],"quartiles.":[98],"Incident":[99],"defined":[103],"\u2265":[106],"3.62":[107],"mmol/L":[108],"or":[109],"initiation":[110],"lipid-lowering":[112],"therapy.":[113],"Cox":[114],"proportional":[115],"hazards":[116],"models":[117],"used":[119],"estimate":[121],"hazard":[123,156],"ratios":[124],"(HRs),":[125],"after":[126],"adjusting":[127],"for":[128,163,173,188,248],"demographic,":[129],"lifestyle,":[130],"clinical":[132],"factors.":[133],"RESULTS:":[134],"During":[135],"mean":[137],"follow-up":[138],"period":[139],"5.02":[141],"years,":[142],"466":[143],"females":[144],"424":[146],"males":[147],"developed":[148],"levels.":[151],"Among":[152,176],"females,":[153],"adjusted":[155,180],"(HR)":[158],"(95%":[159,182],"confidence":[160],"interval":[161],"[CI])":[162],"quartile":[164,167],"4":[165],"versus":[166],"1":[168],"1.95":[170],"(1.41-2.71;":[171],"p":[172,187],"trend":[174,189],"\uff1c0.0001).":[175],"males,":[177],"corresponding":[179],"HR":[181],"CI)":[183],"1.61":[185],"(1.18-2.21;":[186],"=":[190],"0.001).":[191],"A":[192,210,224],"higher":[193],"associated":[196,228],"an":[198,230],"increased":[199,231],"risk":[200,232],"both":[206],"sexes":[207],"(trend":[208],"p\uff1c0.01).":[209],"threshold":[212],"approximately":[214],"0.5":[215],"corresponded":[216],"notable":[219],"increase":[220],"risk.":[222],"CONCLUSION:":[223],"Higher":[225],"LDL-C.":[236],"These":[237],"findings":[238],"suggest":[239],"that":[240],"may":[242],"be":[243],"useful":[245],"anthropometric":[246],"indicator":[247],"identifying":[249],"individuals":[250],"risk,":[252],"although":[253],"further":[254],"studies":[255],"are":[256],"required.":[257]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-09-01T00:00:00"}