{"id":"https://openalex.org/W7204834009","doi":"https://doi.org/10.64898/2026.08.26.26361348","title":"Burr-Hole Intersection of Middle Meningeal Artery Branches and Recurrence in Chronic Subdural Haematoma: a Multicentre Retrospective Cohort Study","display_name":"Burr-Hole Intersection of Middle Meningeal Artery Branches and Recurrence in Chronic Subdural Haematoma: a Multicentre Retrospective Cohort Study","publication_year":2026,"publication_date":"2026-08-31","ids":{"openalex":"https://openalex.org/W7204834009","doi":"https://doi.org/10.64898/2026.08.26.26361348"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.26.26361348","doi":"https://doi.org/10.64898/2026.08.26.26361348","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.26.26361348","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/31/2026.08.26.26361348.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/31/2026.08.26.26361348.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148775131","display_name":"Tymour M Saba","orcid":"https://orcid.org/0009-0001-0604-7948","observed_orcids":["https://orcid.org/0009-0001-0604-7948"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tymour M Saba","raw_affiliation_strings":["Department of Medicine, University College London, London, UK"],"raw_orcid":"https://orcid.org/0009-0001-0604-7948","affiliations":[{"raw_affiliation_string":"Department of Medicine, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044271883","display_name":"Jigi Moudgil-Joshi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801259928","display_name":"Royal London Hospital","ror":"https://ror.org/019my5047","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044","https://openalex.org/I2801259928"]},{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jigi Moudgil-Joshi","raw_affiliation_strings":["Department of Medicine, University College London, London, UK","Department of Neurosurgery, Royal London Hospital, London, UK","Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","UCL Hawkes Institute, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Neurosurgery, Royal London Hospital, London, UK","institution_ids":["https://openalex.org/I2801259928"]},{"raw_affiliation_string":"Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","institution_ids":["https://openalex.org/I4210151618"]},{"raw_affiliation_string":"UCL Hawkes Institute, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085205979","display_name":"Anand S Pandit","orcid":"https://orcid.org/0000-0003-4936-4916","observed_orcids":["https://orcid.org/0000-0003-4936-4916"]},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anand S Pandit","raw_affiliation_strings":["Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","UCL Hawkes Institute, University College London, London, UK","UCL Queen Square Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","institution_ids":["https://openalex.org/I4210151618"]},{"raw_affiliation_string":"UCL Hawkes Institute, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Queen Square Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110173818","display_name":"Jack Penn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801259928","display_name":"Royal London Hospital","ror":"https://ror.org/019my5047","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044","https://openalex.org/I2801259928"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jack Penn","raw_affiliation_strings":["Department of Neurosurgery, Royal London Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Royal London Hospital, London, UK","institution_ids":["https://openalex.org/I2801259928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027355372","display_name":"Dermot Henry Mallon","orcid":"https://orcid.org/0000-0001-7434-1201","observed_orcids":["https://orcid.org/0000-0001-7434-1201"]},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dermot Mallon","raw_affiliation_strings":["Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK","UCL Queen Square Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK","institution_ids":["https://openalex.org/I4210151618"]},{"raw_affiliation_string":"UCL Queen Square Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076899222","display_name":"Hani Joseph Marcus","orcid":"https://orcid.org/0000-0001-8000-392X","observed_orcids":["https://orcid.org/0000-0001-8000-392X"]},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hani J Marcus","raw_affiliation_strings":["Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","UCL Hawkes Institute, University College London, London, UK","UCL Queen Square Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","institution_ids":["https://openalex.org/I4210151618"]},{"raw_affiliation_string":"UCL Hawkes Institute, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Queen Square Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016299087","display_name":"Patrick James Grover","orcid":"https://orcid.org/0000-0002-7822-1239","observed_orcids":["https://orcid.org/0000-0002-7822-1239"]},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Patrick Grover","raw_affiliation_strings":["Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","UCL Hawkes Institute, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK","institution_ids":["https://openalex.org/I4210151618"]},{"raw_affiliation_string":"UCL Hawkes Institute, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5044271883"],"corresponding_institution_ids":["https://openalex.org/I2801259928","https://openalex.org/I4210151618","https://openalex.org/I45129253"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12622","display_name":"Neurosurgical Procedures and Complications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12622","display_name":"Neurosurgical Procedures and Complications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13323","display_name":"Spinal Hematomas and Complications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-subdural-hematoma","display_name":"chronic subdural hematoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/middle-meningeal-artery","display_name":"middle meningeal artery","score":0.9139999747276306},{"id":"https://openalex.org/keywords/burr-hole-drainage","display_name":"burr hole drainage","score":0.9300000071525574},{"id":"https://openalex.org/keywords/hematoma-recurrence","display_name":"hematoma recurrence","score":0.7919999957084656},{"id":"https://openalex.org/keywords/neovascularization","display_name":"neovascularization","score":0.6660000085830688},{"id":"https://openalex.org/keywords/embolization","display_name":"embolization","score":0.625}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9409000277519226},{"id":"https://openalex.org/C190892606","wikidata":"https://www.wikidata.org/wiki/Q3512464","display_name":"Radiological weapon","level":2,"score":0.7773000001907349},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.7692999839782715},{"id":"https://openalex.org/C2777710412","wikidata":"https://www.wikidata.org/wiki/Q500563","display_name":"Middle meningeal artery","level":3,"score":0.7458999752998352},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5870000123977661},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5580000281333923},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.516700029373169},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4893999993801117},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.45809999108314514},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4115999937057495},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.29429998993873596},{"id":"https://openalex.org/C2775841333","wikidata":"https://www.wikidata.org/wiki/Q498179","display_name":"Middle cerebral artery","level":3,"score":0.28529998660087585},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.2777999937534332}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.08.26.26361348","doi":"https://doi.org/10.64898/2026.08.26.26361348","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.26.26361348","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/31/2026.08.26.26361348.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.08.26.26361348","doi":"https://doi.org/10.64898/2026.08.26.26361348","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.26.26361348","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/31/2026.08.26.26361348.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320325311","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44"},{"id":"https://openalex.org/F4320335827","display_name":"UCLH Biomedical Research Centre","ror":"https://ror.org/03r9qc142"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204834009.pdf","grobid_xml":"https://content.openalex.org/works/W7204834009.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2004686468","https://openalex.org/W2018704882","https://openalex.org/W2106170172","https://openalex.org/W2120288374","https://openalex.org/W2585938869","https://openalex.org/W2618152995","https://openalex.org/W2799357948","https://openalex.org/W2901497948","https://openalex.org/W2952094489","https://openalex.org/W3129546467","https://openalex.org/W3175743453","https://openalex.org/W4400015107","https://openalex.org/W4404555056","https://openalex.org/W4404556376","https://openalex.org/W4404558441","https://openalex.org/W4404728004","https://openalex.org/W4411161589","https://openalex.org/W4414186775","https://openalex.org/W4416889943","https://openalex.org/W7147046572"],"related_works":["https://openalex.org/W7213463227","https://openalex.org/W4388681886","https://openalex.org/W4306168125","https://openalex.org/W4416921854","https://openalex.org/W7211962812","https://openalex.org/W4414053916","https://openalex.org/W4402574451","https://openalex.org/W3209201835","https://openalex.org/W7168243157","https://openalex.org/W3174743393"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"and":[2,93,103,116,243],"Objectives":[3],"Recurrence":[4],"following":[5],"burr-hole":[6,38,62,79,266],"drainage":[7,44,63],"of":[8,16,21,40,58,81,157,209,259,273,299],"chronic":[9],"subdural":[10,23],"haematoma":[11],"(cSDH)":[12],"occurs":[13],"in":[14,160,178,198],"10-25%":[15],"cases,":[17],"sustained":[18],"by":[19,26],"neovascularisation":[20],"the":[22,27,82,142,179,199,207,260,277],"neomembrane":[24],"supplied":[25],"middle":[28,261],"meningeal":[29,262],"artery":[30,263],"(MMA).":[31],"MMA":[32,41,84,302],"embolisation":[33],"reduces":[34],"recurrence;":[35],"whether":[36],"incidental":[37],"intersection":[39,80,150,258],"branches":[42],"during":[43,264],"confers":[45],"similar":[46,174],"benefit":[47],"is":[48,268],"unknown.":[49],"Methods":[50],"We":[51],"performed":[52],"a":[53,173,194,287],"multicentre":[54],"retrospective":[55],"cohort":[56,181],"study":[57],"consecutive":[59],"adults":[60],"undergoing":[61],"for":[64,112,286,296],"cSDH":[65,162],"at":[66],"two":[67],"UK":[68],"tertiary":[69],"neurosurgical":[70],"centres.":[71],"Postoperative":[72],"thin-slice":[73],"CT":[74],"was":[75,151,227],"used":[76],"to":[77,136,146],"classify":[78],"underlying":[83],"groove":[85],"(no":[86],"hit,":[87],"distal-branch":[88],"hit":[89,135],"or":[90],"main-branch":[91,139],"hit)":[92],"measure":[94],"perpendicular":[95],"burr-hole-to-MMA-groove":[96,279],"distance.":[97],"Co-primary":[98],"outcomes":[99],"were":[100,125],"radiological":[101,158,210,232],"recurrence":[102,104,128,159,211,233,244,272],"requiring":[105,245],"intervention.":[106],"Patient-clustered":[107],"multivariable":[108],"logistic":[109],"regression":[110],"adjusted":[111,155],"prespecified":[113],"clinical":[114],"covariates":[115],"treating":[117],"site.":[118],"Results":[119],"227":[120],"patients":[121],"(284":[122],"operated":[123],"hemispheres)":[124],"included.":[126],"Radiological":[127],"decreased":[129],"from":[130],"34.4%":[131],"with":[132,138,141,153,172,230,270],"no":[133],"branch":[134],"22.9%":[137],"intersection,":[140],"gradient":[143,281],"confined":[144],"predominantly":[145],"unilateral":[147,161,222,274],"cSDH.":[148],"Main-branch":[149,257],"associated":[152,229,269],"lower":[154,271],"odds":[156,208],"(adjusted":[163,182,212,234,247],"OR":[164,183,213,235,248],"0.30,":[165],"95%":[166,185,215,237,250],"CI":[167,186,216,238,251],"0.11-0.81;":[168],"P":[169,188,218,240,253],"=":[170,189,219,241,254],".018),":[171],"but":[175],"non-significant":[176],"association":[177],"overall":[180,200],"0.53,":[184],"0.26-1.07;":[187],".075).":[190],"Burr-hole-to-MMA-groove":[191],"distance":[192,280],"demonstrated":[193],"more":[195],"consistent":[196],"association:":[197],"cohort,":[201],"each":[202,224],"5-mm":[203,225],"increase":[204,226],"independently":[205,228],"increased":[206],"1.38,":[214],"1.04-1.82;":[217],".025).":[220],"In":[221],"cSDH,":[223,275],"both":[231],"1.45,":[236],"1.03-2.04;":[239],".034)":[242],"intervention":[246],"1.52,":[249],"1.05-2.20;":[252],".027).":[255],"Conclusion":[256],"routine":[265],"surgery":[267],"while":[276],"accompanying":[278],"provides":[282],"biologically":[283],"plausible":[284],"support":[285],"dose-response":[288],"relationship.":[289],"Together,":[290],"these":[291],"findings":[292],"provide":[293],"mechanistic":[294],"rationale":[295],"prospective":[297],"evaluation":[298],"intentional":[300],"neuronavigation-guided":[301],"targeting":[303],"(BURR-MMA;":[304],"NCT07549893":[305],").":[306]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-01T00:00:00"}
