{"id":"https://openalex.org/W7204816395","doi":"https://doi.org/10.1016/j.jbiomech.2026.113551","title":"Soci\u00e9t\u00e9 de Biom\u00e9canique senior investigator award 2024\u2014Hemodynamic performance of a bicuspid venous valve: A computational study","display_name":"Soci\u00e9t\u00e9 de Biom\u00e9canique senior investigator award 2024\u2014Hemodynamic performance of a bicuspid venous valve: A computational study","publication_year":2026,"publication_date":"2026-08-31","ids":{"openalex":"https://openalex.org/W7204816395","doi":"https://doi.org/10.1016/j.jbiomech.2026.113551","pmid":"https://pubmed.ncbi.nlm.nih.gov/42691558"},"language":"en","primary_location":{"id":"doi:10.1016/j.jbiomech.2026.113551","doi":"https://doi.org/10.1016/j.jbiomech.2026.113551","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jbiomech.2026.113551","pdf_url":null,"source":{"id":"https://openalex.org/S181675524","display_name":"Journal of Biomechanics","issn_l":"0021-9290","issn":["0021-9290","1873-2380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomechanics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.jbiomech.2026.113551","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5133210967","display_name":"Barth\u00e9l\u00e9my Thibaud","orcid":"https://orcid.org/0009-0009-1811-195X","observed_orcids":["https://orcid.org/0009-0009-1811-195X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210142014","display_name":"Institut Montpelli\u00e9rain Alexander Grothendieck","ror":"https://ror.org/044kxby82","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210141950","https://openalex.org/I4210142014"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Barthelemy Thibaud","raw_affiliation_strings":["IMAG, Univ Montpellier, CNRS, Montpellier, France. Electronic address: barthelemy.thibaud@umontpellier.fr"],"raw_orcid":"https://orcid.org/0009-0009-1811-195X","affiliations":[{"raw_affiliation_string":"IMAG, Univ Montpellier, CNRS, Montpellier, France. Electronic address: barthelemy.thibaud@umontpellier.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210142014"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066969636","display_name":"Simon Mendez","orcid":"https://orcid.org/0000-0002-0863-2024","observed_orcids":["https://orcid.org/0000-0002-0863-2024"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210142014","display_name":"Institut Montpelli\u00e9rain Alexander Grothendieck","ror":"https://ror.org/044kxby82","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210141950","https://openalex.org/I4210142014"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Simon Mendez","raw_affiliation_strings":["IMAG, Univ Montpellier, CNRS, Montpellier, France. Electronic address: simon.mendez@umontpellier.fr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IMAG, Univ Montpellier, CNRS, Montpellier, France. Electronic address: simon.mendez@umontpellier.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210142014"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012059083","display_name":"Franck Nicoud","orcid":"https://orcid.org/0000-0002-0006-8422","observed_orcids":["https://orcid.org/0000-0002-0006-8422"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210142014","display_name":"Institut Montpelli\u00e9rain Alexander Grothendieck","ror":"https://ror.org/044kxby82","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210141950","https://openalex.org/I4210142014"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Franck Nicoud","raw_affiliation_strings":["IMAG, Univ Montpellier, CNRS, Montpellier, France; Institut Universitaire de France (IUF), Paris, France. Electronic address: franck.nicoud@umontpellier.fr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IMAG, Univ Montpellier, CNRS, Montpellier, France; Institut Universitaire de France (IUF), Paris, France. Electronic address: franck.nicoud@umontpellier.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I185839726","https://openalex.org/I19894307","https://openalex.org/I4210142014"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5133210967"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210142014"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.49823246,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"207","issue":null,"first_page":"113551","last_page":"113551"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":0.4683000147342682,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":0.4683000147342682,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11453","display_name":"Diagnosis and Treatment of Venous Diseases","score":0.22290000319480896,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.08079999685287476,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/femoral-vein","display_name":"femoral vein","score":0.7229999899864197},{"id":"https://openalex.org/keywords/popliteal-vein","display_name":"popliteal vein","score":0.9160000085830688},{"id":"https://openalex.org/keywords/common-femoral-vein","display_name":"common femoral vein","score":0.8399999737739563},{"id":"https://openalex.org/keywords/leaflet-thickness","display_name":"leaflet thickness","score":0.6330000162124634},{"id":"https://openalex.org/keywords/opening-area","display_name":"opening area","score":0.5709999799728394},{"id":"https://openalex.org/keywords/bed-rest","display_name":"bed rest","score":0.3869999945163727}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7064999938011169},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.6934999823570251},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.41530001163482666},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.35109999775886536},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.3458000123500824},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3379000127315521},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.26089999079704285},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.22709999978542328},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.19580000638961792},{"id":"https://openalex.org/C2987190108","wikidata":"https://www.wikidata.org/wiki/Q925667","display_name":"Computational simulation","level":2,"score":0.18219999969005585}],"mesh":[{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005268","descriptor_name":"Femoral Vein","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011152","descriptor_name":"Popliteal Vein","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D055422","descriptor_name":"Venous Valves","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jbiomech.2026.113551","doi":"https://doi.org/10.1016/j.jbiomech.2026.113551","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jbiomech.2026.113551","pdf_url":null,"source":{"id":"https://openalex.org/S181675524","display_name":"Journal of Biomechanics","issn_l":"0021-9290","issn":["0021-9290","1873-2380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomechanics","raw_type":"journal-article"},{"id":"pmid:42691558","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42691558","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomechanics","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05841111v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05841111","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biomechanics, 2026, 207, pp.113551. &#x27E8;10.1016/j.jbiomech.2026.113551&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.jbiomech.2026.113551","doi":"https://doi.org/10.1016/j.jbiomech.2026.113551","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jbiomech.2026.113551","pdf_url":null,"source":{"id":"https://openalex.org/S181675524","display_name":"Journal of Biomechanics","issn_l":"0021-9290","issn":["0021-9290","1873-2380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomechanics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1166658832","display_name":"MUSE","funder_award_id":"ANR-16-IDEX-0006","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5710647032","display_name":null,"funder_award_id":"2024-A0160307194","funder_id":"https://openalex.org/F4320326256","funder_display_name":"Grand \u00c9quipement National De Calcul Intensif"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320326256","display_name":"Grand \u00c9quipement National De Calcul Intensif","ror":"https://ror.org/0010d1q40"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1969240805","https://openalex.org/W1977516243","https://openalex.org/W1990175697","https://openalex.org/W2034343726","https://openalex.org/W2038400704","https://openalex.org/W2040611909","https://openalex.org/W2046595475","https://openalex.org/W2104444844","https://openalex.org/W2130232869","https://openalex.org/W2140586947","https://openalex.org/W2171168738","https://openalex.org/W2173980858","https://openalex.org/W2180762426","https://openalex.org/W2288213514","https://openalex.org/W2344977044","https://openalex.org/W2523048803","https://openalex.org/W2545109774","https://openalex.org/W2561945251","https://openalex.org/W2741595013","https://openalex.org/W2792653497","https://openalex.org/W2800492050","https://openalex.org/W2884348623","https://openalex.org/W2903711325","https://openalex.org/W2945833591","https://openalex.org/W2984428683","https://openalex.org/W2990087370","https://openalex.org/W2998798861","https://openalex.org/W3006760687","https://openalex.org/W3084394784","https://openalex.org/W3107125378","https://openalex.org/W3116438377","https://openalex.org/W3146967241","https://openalex.org/W3184132221","https://openalex.org/W3208095882","https://openalex.org/W4200478730","https://openalex.org/W4205147095","https://openalex.org/W4283162424","https://openalex.org/W4321605904","https://openalex.org/W4403128056","https://openalex.org/W4404946164","https://openalex.org/W4407317658"],"related_works":["https://openalex.org/W2132468685","https://openalex.org/W2140586947","https://openalex.org/W1969240805","https://openalex.org/W2469392120","https://openalex.org/W7015243429","https://openalex.org/W4366524944","https://openalex.org/W1486171856","https://openalex.org/W2083589907","https://openalex.org/W2945833591","https://openalex.org/W3116438377"],"abstract_inverted_index":{"A":[0],"3D":[1],"bicuspid":[2],"venous":[3,145],"valve":[4,114,157],"model":[5,22,132],"is":[6,23],"used":[7],"to":[8,25,42,140],"investigate":[9],"the":[10,27,84,96,102,121,127],"biomechanical":[11],"role":[12],"of":[13,80,104],"leaflet":[14,59],"buckling":[15,60],"in":[16,44,83,108],"achieving":[17],"efficient,":[18],"low-pressure":[19],"opening.":[20],"The":[21],"parameterized":[24],"represent":[26],"femoral":[28,31],"vein,":[29,32,35],"common":[30],"and":[33,38,93,120],"popliteal":[34],"with":[36,52,95,117,155],"sizes":[37],"flow":[39,110,150],"rates":[40],"scaled":[41],"match":[43],"vivo":[45],"conditions.":[46,162],"Using":[47],"a":[48,75],"body-fitted":[49],"numerical":[50,142],"method":[51],"semi-implicit":[53],"predictor-corrector":[54],"coupling,":[55],"we":[56],"demonstrate":[57],"that":[58],"enables":[61],"opening":[62,77,125],"through":[63],"low-energy":[64],"bending":[65],"rather":[66],"than":[67,89],"energetically":[68],"costly":[69],"elastic":[70],"stretching.":[71],"This":[72],"design":[73],"ensures":[74],"maximum":[76],"pressure":[78,99,128,137],"loss":[79,129,138],"42":[81],"Pa":[82],"cases":[85],"tested,":[86],"significantly":[87],"lower":[88],"previously":[90],"reported":[91],"values":[92],"compatible":[94],"physiologically":[97],"observed":[98],"loss,":[100],"highlighting":[101],"importance":[103],"excess":[105],"surface":[106],"area":[107],"minimizing":[109],"resistance":[111],"while":[112],"maintaining":[113],"competence.":[115],"Even":[116],"thickened":[118],"leaflets":[119],"resulting":[122],"reduced":[123],"effective":[124],"area,":[126],"for":[130],"this":[131],"remains":[133],"largely":[134],"below":[135],"physiological":[136],"compared":[139],"other":[141],"studies":[143],"on":[144],"valves.":[146],"Finally,":[147],"complex":[148],"downstream":[149],"patterns":[151],"suggest":[152],"potential":[153],"interactions":[154],"proximal":[156],"dynamics,":[158],"even":[159],"under":[160],"bed-rest":[161]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2026-09-01T00:00:00"}
