{"id":"https://openalex.org/W7204808448","doi":"https://doi.org/10.2169/internalmedicine.8179-26","title":"Teachable Moments in Alcohol-Related Diseases: A Practical Framework for Promoting Abstinence in General Internal Medicine","display_name":"Teachable Moments in Alcohol-Related Diseases: A Practical Framework for Promoting Abstinence in General Internal Medicine","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7204808448","doi":"https://doi.org/10.2169/internalmedicine.8179-26","pmid":"https://pubmed.ncbi.nlm.nih.gov/42686576"},"language":"en","primary_location":{"id":"doi:10.2169/internalmedicine.8179-26","doi":"https://doi.org/10.2169/internalmedicine.8179-26","is_oa":true,"landing_page_url":"https://doi.org/10.2169/internalmedicine.8179-26","pdf_url":"https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_8179-26/_pdf","source":{"id":"https://openalex.org/S154471048","display_name":"Internal Medicine","issn_l":"0918-2918","issn":["0918-2918","1349-7235"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_8179-26/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003480697","display_name":"Tomoko Tadokoro","orcid":"https://orcid.org/0000-0001-9975-386X","observed_orcids":["https://orcid.org/0000-0001-9975-386X"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoko Tadokoro","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085777607","display_name":"Asahiro Morishita","orcid":"https://orcid.org/0000-0002-0760-3045","observed_orcids":["https://orcid.org/0000-0002-0760-3045"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Asahiro Morishita","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121784851","display_name":"Ryosuke Imado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryosuke Imado","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113147016","display_name":"Rie Yano","orcid":"https://orcid.org/0009-0001-4155-2376","observed_orcids":["https://orcid.org/0009-0001-4155-2376"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Rie Yano","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010387793","display_name":"M. Nakahara","orcid":"https://orcid.org/0000-0002-3227-0801","observed_orcids":["https://orcid.org/0000-0002-3227-0801"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mai Nakahara","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075621924","display_name":"Kyoko Oura","orcid":"https://orcid.org/0000-0002-9531-7240","observed_orcids":["https://orcid.org/0000-0002-9531-7240"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kyoko Oura","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Koji Fujita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Fujita","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019668537","display_name":"Shima Mimura","orcid":"https://orcid.org/0000-0002-9574-0479","observed_orcids":["https://orcid.org/0000-0002-9574-0479"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shima Mimura","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013902375","display_name":"Joji Tani","orcid":"https://orcid.org/0000-0001-8801-2505","observed_orcids":["https://orcid.org/0000-0001-8801-2505"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Joji Tani","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003851390","display_name":"Hideki Kobara","orcid":"https://orcid.org/0000-0002-8508-827X","observed_orcids":["https://orcid.org/0000-0002-8508-827X"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideki Kobara","raw_affiliation_strings":["Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan","institution_ids":["https://openalex.org/I201933988"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I201933988"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.66400228,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.6958000063896179,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.6958000063896179,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.302700012922287,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12494","display_name":"Alcoholism and Thiamine Deficiency","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alcohol-related-disorders","display_name":"alcohol-related disorders","score":0.8360000252723694},{"id":"https://openalex.org/keywords/teachable-moments","display_name":"teachable moments","score":0.7910000085830688},{"id":"https://openalex.org/keywords/brief-intervention","display_name":"brief intervention","score":0.8569999933242798},{"id":"https://openalex.org/keywords/alcoholic-liver-disease","display_name":"alcoholic liver disease","score":0.6769999861717224},{"id":"https://openalex.org/keywords/alcohol-related-cancer","display_name":"alcohol-related cancer","score":0.925000011920929},{"id":"https://openalex.org/keywords/acute-pancreatitis","display_name":"acute pancreatitis","score":0.8870000243186951},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.9769999980926514},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9639999866485596},{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gout","display_name":"gout","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sleep-disturbance","display_name":"sleep disorders","score":0.9860000014305115},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.9670000076293945},{"id":"https://openalex.org/keywords/nutritional-rehabilitation","display_name":"nutritional rehabilitation","score":0.9710000157356262},{"id":"https://openalex.org/keywords/aldh2-polymorphism","display_name":"ALDH2 polymorphism","score":0.953000009059906},{"id":"https://openalex.org/keywords/east-asian-patients","display_name":"East Asian patients","score":0.5249999761581421},{"id":"https://openalex.org/keywords/behaviour-change-interventions","display_name":"behaviour change interventions","score":0.5540000200271606}],"concepts":[{"id":"https://openalex.org/C93206822","wikidata":"https://www.wikidata.org/wiki/Q7691177","display_name":"Teachable moment","level":2,"score":0.8880000114440918},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8343999981880188},{"id":"https://openalex.org/C2780687700","wikidata":"https://www.wikidata.org/wiki/Q210978","display_name":"Abstinence","level":2,"score":0.7279000282287598},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.41499999165534973},{"id":"https://openalex.org/C183698672","wikidata":"https://www.wikidata.org/wiki/Q3332444","display_name":"Behavioral medicine","level":2,"score":0.3790999948978424},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.35839998722076416},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3481999933719635},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.335099995136261},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.32829999923706055},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.31940001249313354},{"id":"https://openalex.org/C3018553135","wikidata":"https://www.wikidata.org/wiki/Q67004728","display_name":"Medication adherence","level":2,"score":0.26269999146461487},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.25049999356269836}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.2169/internalmedicine.8179-26","doi":"https://doi.org/10.2169/internalmedicine.8179-26","is_oa":true,"landing_page_url":"https://doi.org/10.2169/internalmedicine.8179-26","pdf_url":"https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_8179-26/_pdf","source":{"id":"https://openalex.org/S154471048","display_name":"Internal Medicine","issn_l":"0918-2918","issn":["0918-2918","1349-7235"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine","raw_type":"journal-article"},{"id":"pmid:42686576","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42686576","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal medicine (Tokyo, Japan)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2169/internalmedicine.8179-26","doi":"https://doi.org/10.2169/internalmedicine.8179-26","is_oa":true,"landing_page_url":"https://doi.org/10.2169/internalmedicine.8179-26","pdf_url":"https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_8179-26/_pdf","source":{"id":"https://openalex.org/S154471048","display_name":"Internal Medicine","issn_l":"0918-2918","issn":["0918-2918","1349-7235"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204808448.pdf","grobid_xml":"https://content.openalex.org/works/W7204808448.grobid-xml"},"referenced_works_count":2,"referenced_works":["https://openalex.org/W4416222710","https://openalex.org/W7124167360"],"related_works":["https://openalex.org/W1525129746","https://openalex.org/W853047119","https://openalex.org/W2030152165","https://openalex.org/W6898682735","https://openalex.org/W2993785561","https://openalex.org/W2414928240","https://openalex.org/W2026336118","https://openalex.org/W4283816835","https://openalex.org/W3092395099","https://openalex.org/W2029578283"],"abstract_inverted_index":{"Alcohol":[0],"consumption":[1,95],"remains":[2],"a":[3,25,52],"leading":[4],"preventable":[5],"cause":[6],"of":[7,32,46],"morbidity":[8],"and":[9,58,84,86,114,118,130],"mortality;":[10],"however,":[11],"abstinence":[12,91],"counseling":[13],"is":[14,43],"not":[15],"routinely":[16],"implemented":[17],"in":[18,50,122,127],"general":[19],"internal":[20],"medicine.":[21],"This":[22],"review":[23],"proposes":[24],"Japan-oriented":[26],"framework":[27,42],"for":[28,61],"translating":[29],"the":[30,44,47,88],"diagnosis":[31,54],"alcohol-related":[33,68,73],"diseases":[34],"into":[35],"behavioral":[36],"change":[37],"interventions.":[38],"Central":[39],"to":[40],"this":[41],"concept":[45],"\"teachable":[48],"moment,\"":[49],"which":[51],"new":[53],"increases":[55],"patient":[56],"motivation":[57],"creates":[59],"opportunities":[60],"timely":[62],"clinical":[63],"intervention.":[64],"We":[65,99],"reviewed":[66],"common":[67,121],"conditions,":[69],"including":[70],"liver":[71,109],"disease,":[72],"cancers,":[74],"acute":[75],"pancreatitis,":[76],"atrial":[77],"fibrillation,":[78],"hypertension,":[79],"hypertriglyceridemia,":[80],"gout,":[81],"sleep":[82],"disorders,":[83],"pneumonia,":[85],"summarized":[87],"evidence":[89],"that":[90,105],"or":[92],"reduced":[93],"alcohol":[94],"can":[96],"improve":[97],"outcomes.":[98],"also":[100],"present":[101],"an":[102],"integrated":[103],"approach":[104],"combines":[106],"brief":[107],"intervention,":[108],"function-guided":[110],"pharmacotherapy,":[111],"nutritional":[112],"rehabilitation,":[113],"specialist":[115],"collaboration.":[116],"ALDH2":[117],"ADH1B":[119],"polymorphisms,":[120],"East":[123],"Asians,":[124],"may":[125],"aid":[126],"risk":[128],"stratification":[129],"treatment":[131],"selection.":[132]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-01T00:00:00"}