{"id":"https://openalex.org/W7204794840","doi":"https://doi.org/10.1016/j.aninu.2026.03.015","title":"Dietary phosphatidylinositol promotes ovarian maturation in Pacific white shrimp (Penaeus vannamei) via altered lipid mobilization and hormonal regulation","display_name":"Dietary phosphatidylinositol promotes ovarian maturation in Pacific white shrimp (Penaeus vannamei) via altered lipid mobilization and hormonal regulation","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7204794840","doi":"https://doi.org/10.1016/j.aninu.2026.03.015","pmid":"https://pubmed.ncbi.nlm.nih.gov/42894771","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13677240"},"language":"en","primary_location":{"id":"doi:10.1016/j.aninu.2026.03.015","doi":"https://doi.org/10.1016/j.aninu.2026.03.015","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.aninu.2026.03.015","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2405654526001307/pdf","source":{"id":"https://openalex.org/S2764806997","display_name":"Animal nutrition","issn_l":"2405-6383","issn":["2405-6383","2405-6545"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320345","host_organization_name":"KeAi","host_organization_lineage":["https://openalex.org/P4310320345","https://openalex.org/P4310320990"],"host_organization_lineage_names":["KeAi","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2405654526001307/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148778897","display_name":"Long Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66867065","display_name":"East China Normal University","ror":"https://ror.org/02n96ep67","country_code":"CN","type":"education","lineage":["https://openalex.org/I66867065"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Long Zhang","raw_affiliation_strings":["School of Life Sciences, East China Normal University, Shanghai 200241, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, East China Normal University, Shanghai 200241, China","institution_ids":["https://openalex.org/I66867065"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148811235","display_name":"Tong Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66867065","display_name":"East China Normal University","ror":"https://ror.org/02n96ep67","country_code":"CN","type":"education","lineage":["https://openalex.org/I66867065"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tong Chang","raw_affiliation_strings":["School of Life Sciences, East China Normal University, Shanghai 200241, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, East China Normal University, Shanghai 200241, China","institution_ids":["https://openalex.org/I66867065"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034819739","display_name":"Xiaolong Liang","orcid":"https://orcid.org/0000-0001-7545-7812","observed_orcids":["https://orcid.org/0000-0001-7545-7812"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaolong Liang","raw_affiliation_strings":["School of Marine Biology and Fisheries, Hainan University, Haikou 570228, Hainan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Marine Biology and Fisheries, Hainan University, Haikou 570228, Hainan, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071902415","display_name":"Fenglu Han","orcid":"https://orcid.org/0000-0002-9805-6146","observed_orcids":["https://orcid.org/0000-0002-9805-6146"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fenglu Han","raw_affiliation_strings":["School of Marine Biology and Fisheries, Hainan University, Haikou 570228, Hainan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Marine Biology and Fisheries, Hainan University, Haikou 570228, Hainan, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124699570","display_name":"Chang Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chang Xu","raw_affiliation_strings":["School of Marine Biology and Fisheries, Hainan University, Haikou 570228, Hainan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Marine Biology and Fisheries, Hainan University, Haikou 570228, Hainan, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070432642","display_name":"Erchao Li","orcid":"https://orcid.org/0000-0001-8495-2241","observed_orcids":["https://orcid.org/0000-0001-8495-2241"]},"institutions":[{"id":"https://openalex.org/I66867065","display_name":"East China Normal University","ror":"https://ror.org/02n96ep67","country_code":"CN","type":"education","lineage":["https://openalex.org/I66867065"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Erchao Li","raw_affiliation_strings":["School of Life Sciences, East China Normal University, Shanghai 200241, China"],"raw_orcid":"https://orcid.org/0000-0001-8495-2241","affiliations":[{"raw_affiliation_string":"School of Life Sciences, East China Normal University, Shanghai 200241, China","institution_ids":["https://openalex.org/I66867065"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070432642"],"corresponding_institution_ids":["https://openalex.org/I66867065"],"apc_list":{"value":1462,"currency":"USD","value_usd":1462},"apc_paid":{"value":1462,"currency":"USD","value_usd":1462},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.57448849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":null,"first_page":"424","last_page":"442"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11004","display_name":"Crustacean biology and ecology","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phosphatidylinositol","display_name":"phosphatidylinositol","score":0.9909999966621399},{"id":"https://openalex.org/keywords/litopenaeus-vannamei","display_name":"Litopenaeus vannamei","score":0.9319999814033508},{"id":"https://openalex.org/keywords/ovarian-maturation","display_name":"ovarian maturation","score":0.9929999709129333},{"id":"https://openalex.org/keywords/broodstock-nutrition","display_name":"broodstock nutrition","score":0.8320000171661377},{"id":"https://openalex.org/keywords/lipid-mobilization","display_name":"lipid mobilization","score":0.875},{"id":"https://openalex.org/keywords/hepatopancreas","display_name":"hepatopancreas","score":0.6710000038146973},{"id":"https://openalex.org/keywords/plasma-lipoproteins","display_name":"serum lipoproteins","score":0.7720000147819519},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.7609999775886536},{"id":"https://openalex.org/keywords/progesterone","display_name":"progesterone","score":0.9850000143051147},{"id":"https://openalex.org/keywords/molt-inhibiting-hormone","display_name":"molt-inhibiting hormone","score":0.9900000095367432},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.4699999988079071},{"id":"https://openalex.org/keywords/oogenesis","display_name":"oogenesis","score":0.5389999747276306},{"id":"https://openalex.org/keywords/shrimp-farming","display_name":"shrimp aquaculture","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7903000116348267},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7702999711036682},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6870999932289124},{"id":"https://openalex.org/C2776841996","wikidata":"https://www.wikidata.org/wiki/Q1517781","display_name":"Shrimp","level":2,"score":0.6704999804496765},{"id":"https://openalex.org/C2780610907","wikidata":"https://www.wikidata.org/wiki/Q2273248","display_name":"Phosphatidylinositol","level":3,"score":0.6187999844551086},{"id":"https://openalex.org/C156708679","wikidata":"https://www.wikidata.org/wiki/Q242412","display_name":"Mobilization","level":2,"score":0.5841000080108643},{"id":"https://openalex.org/C56273599","wikidata":"https://www.wikidata.org/wiki/Q3122841","display_name":"White (mutation)","level":3,"score":0.5339999794960022},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5116999745368958},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.31540000438690186},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.3084000051021576},{"id":"https://openalex.org/C2778324911","wikidata":"https://www.wikidata.org/wiki/Q9631","display_name":"Ovary","level":2,"score":0.29330000281333923},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.2757999897003174},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.2619999945163727}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.aninu.2026.03.015","doi":"https://doi.org/10.1016/j.aninu.2026.03.015","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.aninu.2026.03.015","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2405654526001307/pdf","source":{"id":"https://openalex.org/S2764806997","display_name":"Animal nutrition","issn_l":"2405-6383","issn":["2405-6383","2405-6545"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320345","host_organization_name":"KeAi","host_organization_lineage":["https://openalex.org/P4310320345","https://openalex.org/P4310320990"],"host_organization_lineage_names":["KeAi","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Nutrition","raw_type":"journal-article"},{"id":"pmid:42894771","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42894771","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal nutrition (Zhongguo xu mu shou yi xue hui)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13677240","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13677240/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anim Nutr","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:f02474ea43824336b08afe98e56eb2ff","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/f02474ea43824336b08afe98e56eb2ff","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Animal Nutrition, Vol 27, Iss , Pp 424-442 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.aninu.2026.03.015","doi":"https://doi.org/10.1016/j.aninu.2026.03.015","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.aninu.2026.03.015","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2405654526001307/pdf","source":{"id":"https://openalex.org/S2764806997","display_name":"Animal nutrition","issn_l":"2405-6383","issn":["2405-6383","2405-6545"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320345","host_organization_name":"KeAi","host_organization_lineage":["https://openalex.org/P4310320345","https://openalex.org/P4310320990"],"host_organization_lineage_names":["KeAi","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.8409000039100647,"display_name":"Zero hunger"},{"id":"https://metadata.un.org/sdg/14","score":0.5769000053405762,"display_name":"Life below water"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1408056902","display_name":null,"funder_award_id":"2023YFD2402000","funder_id":"https://openalex.org/F4320327287","funder_display_name":"Ministry of Agriculture and Rural Affairs of the People's Republic of China"},{"id":"https://openalex.org/G4980919984","display_name":null,"funder_award_id":"ZDYF2024XDNY185","funder_id":"https://openalex.org/F4320324882","funder_display_name":"Hainan Provincial Department of Science and Technology"},{"id":"https://openalex.org/G812088302","display_name":null,"funder_award_id":"2023YFD2402000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320324882","display_name":"Hainan Provincial Department of Science and Technology","ror":"https://ror.org/03rbw2w25"},{"id":"https://openalex.org/F4320327287","display_name":"Ministry of Agriculture and Rural Affairs of the People's Republic of China","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204794840.pdf","grobid_xml":"https://content.openalex.org/works/W7204794840.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W348988873","https://openalex.org/W1475381583","https://openalex.org/W1494506878","https://openalex.org/W1908640189","https://openalex.org/W1966452335","https://openalex.org/W1969478183","https://openalex.org/W1980537495","https://openalex.org/W1985170971","https://openalex.org/W1997209468","https://openalex.org/W2004445008","https://openalex.org/W2006718161","https://openalex.org/W2026988896","https://openalex.org/W2030946819","https://openalex.org/W2042945054","https://openalex.org/W2046547289","https://openalex.org/W2066124669","https://openalex.org/W2077972025","https://openalex.org/W2078233379","https://openalex.org/W2082011949","https://openalex.org/W2084744450","https://openalex.org/W2084980375","https://openalex.org/W2089444832","https://openalex.org/W2091917635","https://openalex.org/W2094722357","https://openalex.org/W2098952224","https://openalex.org/W2107277218","https://openalex.org/W2124143239","https://openalex.org/W2126747339","https://openalex.org/W2131140798","https://openalex.org/W2147249942","https://openalex.org/W2153336237","https://openalex.org/W2161036895","https://openalex.org/W2162228329","https://openalex.org/W2163774637","https://openalex.org/W2165397217","https://openalex.org/W2238186256","https://openalex.org/W2265535428","https://openalex.org/W2311134382","https://openalex.org/W2563681462","https://openalex.org/W2763178964","https://openalex.org/W2769222914","https://openalex.org/W2789863163","https://openalex.org/W2894593905","https://openalex.org/W2949209856","https://openalex.org/W2983472618","https://openalex.org/W2986128805","https://openalex.org/W3000239131","https://openalex.org/W3041036348","https://openalex.org/W3047062022","https://openalex.org/W3092132637","https://openalex.org/W3098982938","https://openalex.org/W3138591064","https://openalex.org/W3176402538","https://openalex.org/W3199358957","https://openalex.org/W3199660841","https://openalex.org/W4205909438","https://openalex.org/W4220870970","https://openalex.org/W4280651132","https://openalex.org/W4285741776","https://openalex.org/W4308791540","https://openalex.org/W4309506673","https://openalex.org/W4311702729","https://openalex.org/W4320732081","https://openalex.org/W4384202290","https://openalex.org/W4385973094","https://openalex.org/W4387653502","https://openalex.org/W4387908139","https://openalex.org/W4388516471","https://openalex.org/W4388940632","https://openalex.org/W4391292914","https://openalex.org/W4394912776","https://openalex.org/W4397292125","https://openalex.org/W4399426680","https://openalex.org/W4405954894","https://openalex.org/W4406285774","https://openalex.org/W4406606418","https://openalex.org/W4407925870"],"related_works":["https://openalex.org/W7214168673","https://openalex.org/W4220870970","https://openalex.org/W4413407110","https://openalex.org/W4394912776","https://openalex.org/W7023310441","https://openalex.org/W4415541990","https://openalex.org/W4402481891","https://openalex.org/W6986159673","https://openalex.org/W4285037658","https://openalex.org/W2089444832"],"abstract_inverted_index":{"Phosphatidylinositol":[0],"(PI)":[1],"is":[2,361],"an":[3],"important":[4],"phospholipid":[5],"involved":[6],"in":[7,19,23,42,168,178,188,204,219,382],"membrane":[8],"structure,":[9],"lipid":[10,276,343],"transport,":[11],"and":[12,33,56,71,104,129,138,175,215,240,256,262,278,280,292,301,303,307,316,345],"cellular":[13],"signaling,":[14,283],"but":[15],"its":[16],"nutritional":[17],"role":[18],"regulating":[20],"ovarian":[21,40,92,143,331,339],"maturation":[22,340],"crustacean":[24],"broodstock":[25,44,379],"remains":[26],"poorly":[27],"understood.":[28],"To":[29],"elucidate":[30],"the":[31,111,116,122,131,142,169,179,189,195,205,370],"effects":[32],"mechanisms":[34],"by":[35,146,341],"which":[36],"dietary":[37,197,335],"PI":[38,66,118,191,336],"modulates":[39],"development":[41],"female":[43],"of":[45,80,141,288,298,313,357],"Pacific":[46],"white":[47],"shrimp":[48,74,106,383],"(":[49,125,134,171,181,208,229,242,252,264],"Penaeus":[50],"vannamei":[51],"),":[52],"five":[53,98],"isonitrogenous,":[54],"isolipidic,":[55],"semi-purified":[57],"diets":[58],"containing":[59],"0.0,":[60],"0.2%,":[61],"0.4%,":[62],"0.6%,":[63],"or":[64],"0.8%":[65,241],"(dry-matter":[67,359],"basis)":[68,360],"were":[69,95,185],"formulated":[70],"fed":[72],"to":[73,97],"for":[75,275,281],"28":[76],"d.":[77],"A":[78,353],"total":[79,200],"160":[81],"seven-month-old":[82],"females":[83],"(initial":[84],"body":[85],"weight":[86],"39.70":[87],"\u00b1":[88],"1.80":[89],"g)":[90],"at":[91,227,238,260],"stage":[93,155,160],"I":[94],"allocated":[96],"treatments":[99],"with":[100,110,194,295,349,367],"four":[101],"replicates":[102],"each":[103,140],"eight":[105],"per":[107],"replicate.":[108],"Compared":[109],"control":[112],"group":[113,192,207],"(0.0":[114],"PI),":[115],"0.6%":[117,190,206,228,239,263,368],"diet":[119],"significantly":[120],"increased":[121,236],"gonadosomatic":[123],"index":[124,133],"P":[126,135,152,157,162,172,182,209,230,243,253,265],"<":[127,173,183,231,244],"0.001)":[128,174,184],"reduced":[130,257],"hepatosomatic":[132],"=":[136,153,158,163,210,254,266],"0.030)":[137],"shortened":[139],"stages":[144],"I\u2013III":[145],"approximately":[147],"two":[148],"days":[149],"(stage":[150],"I,":[151],"0.056;":[154],"II,":[156],"0.159;":[159],"III,":[161],"0.007).":[164],"Mean":[165],"oocyte":[166],"area":[167,177],"ovary":[170],"lipid-droplet":[176],"hepatopancreas":[180],"both":[186],"greatest":[187],"compared":[193],"other":[196],"groups.":[198],"Ovarian":[199],"cholesterol":[201],"was":[202],"highest":[203],"0.029).":[211],"Serum":[212],"high-density":[213],"lipoprotein":[214,217],"low-density":[216],"declined":[218],"most":[220],"PI-supplemented":[221],"groups,":[222],"reaching":[223],"their":[224],"lowest":[225],"levels":[226,297],"0.05).":[232],"Endocrine":[233],"profiling":[234],"showed":[235],"estradiol":[237],"0.001),":[245],"elevated":[246],"progesterone":[247],"across":[248],"all":[249],"supplemented":[250],"groups":[251],"0.007),":[255],"molt-inhibiting":[258],"hormone":[259],"0.2%":[261],"0.043).":[267],"Transcriptomics":[268],"identified":[269],"421":[270],"differentially":[271],"expressed":[272],"genes":[273],"enriched":[274],"synthesis":[277],"transport":[279],"TGF-\u03b2/Notch":[282],"while":[284],"metabolomics":[285],"revealed":[286],"upregulation":[287],"D-sphingosine,":[289],"palmitic":[290],"acid,":[291,294],"stearic":[293],"decreased":[296],"purines":[299],"(guanine":[300],"hypoxanthine)":[302],"B-vitamin":[304],"intermediates":[305],"(riboflavinand":[306],"pantothenate).":[308],"Multi-omics":[309],"integration":[310],"indicated":[311],"potentiation":[312],"sphingolipid":[314],"metabolism":[315],"fatty-acid":[317],"biosynthesis,":[318],"alongside":[319],"heightened":[320],"consumption":[321],"within":[322],"purine":[323],"metabolism,":[324],"as":[325],"a":[326],"potential":[327],"regulatory":[328],"pathway":[329],"promoting":[330],"maturation.":[332],"In":[333],"summary,":[334],"may":[337],"facilitate":[338],"coordinating":[342],"mobilization":[344],"steroidogenesis,":[346],"potentially":[347],"interacting":[348],"developmental":[350],"signaling":[351],"pathways.":[352],"recommended":[354],"supplementation":[355],"range":[356],"0.442%\u20130.586%":[358],"suggested":[362],"based":[363],"on":[364],"dose-response":[365],"modeling,":[366],"yielding":[369],"significant":[371],"response.":[372],"These":[373],"findings":[374],"provide":[375],"new":[376],"insights":[377],"into":[378],"nutrition":[380],"strategy":[381],"aquaculture.":[384]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-09-01T00:00:00"}