{"id":"https://openalex.org/W7204774038","doi":"https://doi.org/10.64898/2026.08.28.747878","title":"Intermittent Cranial Accelerometric Pulses - a Potential Marker of Neurodegenerative Disease","display_name":"Intermittent Cranial Accelerometric Pulses - a Potential Marker of Neurodegenerative Disease","publication_year":2026,"publication_date":"2026-08-31","ids":{"openalex":"https://openalex.org/W7204774038","doi":"https://doi.org/10.64898/2026.08.28.747878","pmid":"https://pubmed.ncbi.nlm.nih.gov/42798372","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13605723"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.28.747878","doi":"https://doi.org/10.64898/2026.08.28.747878","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.28.747878","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/31/2026.08.28.747878.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/31/2026.08.28.747878.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070350108","display_name":"Christine M. Walsh","orcid":"https://orcid.org/0000-0003-2282-1531","observed_orcids":["https://orcid.org/0000-0003-2282-1531"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christine M. Walsh","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005737580","display_name":"Paul A. Lovoi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul A. Lovoi","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001095788","display_name":"Leslie M. Yack","orcid":"https://orcid.org/0000-0002-3477-4683","observed_orcids":["https://orcid.org/0000-0002-3477-4683"]},"institutions":[{"id":"https://openalex.org/I1315708478","display_name":"San Francisco VA Medical Center","ror":"https://ror.org/049peqw80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1315708478","https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210143381"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leslie Yack","raw_affiliation_strings":["Department of Psychiatry University of California San Francisco; San Francisco, USA","San Francisco Veterans Affairs Medical Center; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"San Francisco Veterans Affairs Medical Center; San Francisco, USA","institution_ids":["https://openalex.org/I1315708478"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100644992","display_name":"Joseph Chen","orcid":"https://orcid.org/0000-0002-7585-0662","observed_orcids":["https://orcid.org/0000-0002-7585-0662"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Chen","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA","University of California Los Angeles; Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"University of California Los Angeles; Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076756380","display_name":"Natalie Pandher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Natalie Pandher","raw_affiliation_strings":["Department of Psychiatry University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074332054","display_name":"Eliot D. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eliot D. Lee","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153232419","display_name":"Thomas Hemphill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Hemphill","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153211539","display_name":"Esther Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Esther Li","raw_affiliation_strings":["Department of Psychiatry University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108859724","display_name":"Dominica Randazzo","orcid":"https://orcid.org/0000-0003-1185-7504","observed_orcids":["https://orcid.org/0000-0003-1185-7504"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dominica Randazzo","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002961570","display_name":"Steve Woodward","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204866599","display_name":"VA Palo Alto Health Care System","ror":"https://ror.org/00nr17z89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I204866599","https://openalex.org/I2799886695","https://openalex.org/I4210125474"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven H. Woodward","raw_affiliation_strings":["National Center for PTSD, Dissemination and Training Division, VA Palo Alto Health Care System; Palo Alto, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for PTSD, Dissemination and Training Division, VA Palo Alto Health Care System; Palo Alto, CA, USA","institution_ids":["https://openalex.org/I204866599"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053096250","display_name":"Thomas C. Neylan","orcid":"https://orcid.org/0000-0002-1572-2626","observed_orcids":["https://orcid.org/0000-0002-1572-2626"]},"institutions":[{"id":"https://openalex.org/I1315708478","display_name":"San Francisco VA Medical Center","ror":"https://ror.org/049peqw80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1315708478","https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210125474","https://openalex.org/I4210143381"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas C. Neylan","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA","Department of Psychiatry University of California San Francisco; San Francisco, USA","San Francisco Veterans Affairs Medical Center; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Psychiatry University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"San Francisco Veterans Affairs Medical Center; San Francisco, USA","institution_ids":["https://openalex.org/I1315708478"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077101946","display_name":"Wade S. Smith","orcid":"https://orcid.org/0000-0003-4174-8333","observed_orcids":["https://orcid.org/0000-0003-4174-8333"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wade S. Smith","raw_affiliation_strings":["Department of Neurology University of California San Francisco; San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of California San Francisco; San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5070350108"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.7440999746322632,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.7440999746322632,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.06710000336170197,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.03779999911785126,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.9049999713897705},{"id":"https://openalex.org/keywords/sleep","display_name":"sleep","score":0.6399999856948853},{"id":"https://openalex.org/keywords/eeg-delta-power","display_name":"EEG delta power","score":0.9279999732971191},{"id":"https://openalex.org/keywords/glymphatic-system","display_name":"glymphatic system","score":0.8529999852180481},{"id":"https://openalex.org/keywords/sleep-stages","display_name":"sleep stages","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.6687999963760376},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.5652999877929688},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5375000238418579},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5189999938011169},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.47929999232292175},{"id":"https://openalex.org/C79191276","wikidata":"https://www.wikidata.org/wiki/Q7259620","display_name":"Pulsatile flow","level":2,"score":0.4740000069141388},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.46459999680519104},{"id":"https://openalex.org/C101054994","wikidata":"https://www.wikidata.org/wiki/Q15474254","display_name":"Glymphatic system","level":3,"score":0.4348999857902527},{"id":"https://openalex.org/C2909515847","wikidata":"https://www.wikidata.org/wiki/Q2623205","display_name":"Delta Rhythm","level":4,"score":0.42820000648498535},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.37860000133514404},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.3605000078678131},{"id":"https://openalex.org/C110539466","wikidata":"https://www.wikidata.org/wiki/Q3964845","display_name":"Slow-wave sleep","level":3,"score":0.33570000529289246},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3246999979019165},{"id":"https://openalex.org/C2779281540","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Central nervous system disease","level":2,"score":0.322299987077713},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3084000051021576},{"id":"https://openalex.org/C2777427615","wikidata":"https://www.wikidata.org/wiki/Q954257","display_name":"Degenerative disease","level":3,"score":0.302700012922287},{"id":"https://openalex.org/C2779213384","wikidata":"https://www.wikidata.org/wiki/Q211402","display_name":"Rapid eye movement sleep","level":3,"score":0.29789999127388},{"id":"https://openalex.org/C112144039","wikidata":"https://www.wikidata.org/wiki/Q4994651","display_name":"K-complex","level":4,"score":0.29019999504089355},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.2736999988555908},{"id":"https://openalex.org/C2910364982","wikidata":"https://www.wikidata.org/wiki/Q35831","display_name":"Sleep Stages","level":4,"score":0.2669000029563904},{"id":"https://openalex.org/C17755696","wikidata":"https://www.wikidata.org/wiki/Q16564780","display_name":"Ictal","level":3,"score":0.2632000148296356},{"id":"https://openalex.org/C143647101","wikidata":"https://www.wikidata.org/wiki/Q2738302","display_name":"Sleep spindle","level":4,"score":0.2605000138282776},{"id":"https://openalex.org/C207743973","wikidata":"https://www.wikidata.org/wiki/Q2623205","display_name":"Delta wave","level":4,"score":0.2554999887943268}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.64898/2026.08.28.747878","doi":"https://doi.org/10.64898/2026.08.28.747878","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.28.747878","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/31/2026.08.28.747878.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:42798372","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42798372","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13605723","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42798372/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.64898/2026.08.28.747878","doi":"https://doi.org/10.64898/2026.08.28.747878","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.28.747878","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/31/2026.08.28.747878.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320316999","display_name":"Prospect Creek Foundation","ror":"https://ror.org/05pnphj78"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204774038.pdf","grobid_xml":"https://content.openalex.org/works/W7204774038.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4410501901","https://openalex.org/W2146288660","https://openalex.org/W4410501455","https://openalex.org/W4389460221","https://openalex.org/W6999837502","https://openalex.org/W1985858442","https://openalex.org/W7171770670","https://openalex.org/W2010513930","https://openalex.org/W7126085502","https://openalex.org/W801937105"],"abstract_inverted_index":{"We":[0,52],"identified":[1],"Intermittent":[2],"Cranial":[3],"Accelerometric":[4],"Pulses":[5],"(ICAPs)":[6],"also":[7],"known":[8],"as":[9,13],"Sleep":[10],"Bursts":[11],"(SBs),":[12],"a":[14,44,145,184],"novel":[15],"phenomenon":[16],"of":[17,46,164,188],"brief":[18],"(1-2":[19],"sec),":[20],"often":[21],"periodic":[22],"bursts":[23],"in":[24,37,43,72,85,94,108,130,150,175],"cranial":[25],"forces":[26],"occurring":[27,112],"during":[28,144],"human":[29,176],"sleep.":[30],"Our":[31],"goal":[32],"was":[33,147],"to":[34,158],"characterize":[35],"SBs":[36,70,76,114,181],"normal":[38],"subjects,":[39],"then":[40],"compare":[41],"SB":[42,99,146,165],"cohort":[45],"subjects":[47,57,63,153],"with":[48,64,101,169],"neurodegenerative":[49],"disease":[50],"(NDD).":[51],"recorded":[53],"32":[54],"cognitively":[55],"healthy":[56],"(23":[58],"-87":[59],"years)":[60],"and":[61,87,137,167],"13":[62],"NDD":[65,95,152],"(51":[66],"-":[67,122],"84":[68],"years).":[69],"occurred":[71,77,100],"all":[73,105,151],"45":[74],"subjects.":[75],"at":[78],"0.57":[79],"SB/min":[80,89],"(once":[81,90],"per":[82,91],"105":[83],"seconds)":[84,93],"controls":[86],"0.40":[88],"150":[92],"(p":[96],"=":[97],"0.0043).":[98],"equal":[102],"rates":[103],"across":[104,154],"sleep":[106,155],"stages":[107,156],"both":[109],"groups.":[110],"When":[111],"periodically,":[113],"had":[115],"modal":[116],"intervals":[117],"(3.75":[118],"bursts/min":[119,124],"(0.0625":[120],"Hz)":[121],"2.67":[123],"(0.044":[125],"Hz)).":[126],"EEG":[127,141,170],"power":[128,143,171],"increased":[129],"the":[131,139],"delta":[132,142],"range":[133],"1-2":[134],"seconds":[135],"before":[136],"following":[138],"SB.":[140],"significantly":[148],"lower":[149],"compared":[157],"controls.":[159],"The":[160],"relatively":[161],"low":[162],"frequency":[163],"events":[166],"synchronization":[168],"has":[172],"no":[173],"parallel":[174],"sleep;":[177],"we":[178],"hypothesize":[179],"that":[180],"may":[182],"represent":[183],"brain-generated":[185],"pulsatile":[186],"component":[187],"brain":[189],"glymphatic":[190],"drainage.":[191]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-01T00:00:00"}