{"id":"https://openalex.org/W7204724034","doi":"https://doi.org/10.1016/s2152-2650(26)02878-8","title":"MM-453: Durability of Response, Mechanisms of Resistance, and Retreatment Outcomes Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Systematic Review","display_name":"MM-453: Durability of Response, Mechanisms of Resistance, and Retreatment Outcomes Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Systematic Review","publication_year":2026,"publication_date":"2026-08-01","ids":{"openalex":"https://openalex.org/W7204724034","doi":"https://doi.org/10.1016/s2152-2650(26)02878-8"},"language":"en","primary_location":{"id":"doi:10.1016/s2152-2650(26)02878-8","doi":"https://doi.org/10.1016/s2152-2650(26)02878-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s2152-2650(26)02878-8","pdf_url":null,"source":{"id":"https://openalex.org/S186546955","display_name":"Clinical Lymphoma Myeloma & Leukemia","issn_l":"2152-2650","issn":["2152-2650","2152-2669"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lymphoma Myeloma and Leukemia","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068204824","display_name":"Mahboob Younus Shaik","orcid":"https://orcid.org/0009-0000-9438-6589","observed_orcids":["https://orcid.org/0009-0000-9438-6589"]},"institutions":[{"id":"https://openalex.org/I4210124418","display_name":"CHI St. Vincent","ror":"https://ror.org/02tr0ps12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210124418"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahboob Younus Shaik","raw_affiliation_strings":["CHI St Vincent Hospital, Hot Springs, AR, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHI St Vincent Hospital, Hot Springs, AR, USA","institution_ids":["https://openalex.org/I4210124418"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148649624","display_name":"Sahar Amjad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177340980","display_name":"Farmingdale State College","ror":"https://ror.org/010thz337","country_code":"US","type":"education","lineage":["https://openalex.org/I177340980"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sahar Amjad","raw_affiliation_strings":["SUNY Farmingdale State College, Farmingdale, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SUNY Farmingdale State College, Farmingdale, NY, USA","institution_ids":["https://openalex.org/I177340980"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090286841","display_name":"Sunilkumar Kakadia","orcid":"https://orcid.org/0000-0002-3312-1605","observed_orcids":["https://orcid.org/0000-0002-3312-1605"]},"institutions":[{"id":"https://openalex.org/I4210124418","display_name":"CHI St. Vincent","ror":"https://ror.org/02tr0ps12","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210124418"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sunil Kakadia","raw_affiliation_strings":["CHI St Vincent Hospital, Hot Springs, AR, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHI St Vincent Hospital, Hot Springs, AR, USA","institution_ids":["https://openalex.org/I4210124418"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":null,"first_page":"S1083","last_page":"S1083"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.6474999785423279,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.6474999785423279,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.34790000319480896,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12534","display_name":"Protein Degradation and Inhibitors","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/car-t-cell-therapy","display_name":"CAR T-cell therapy","score":0.8740000128746033},{"id":"https://openalex.org/keywords/relapsed-refractory-multiple-myeloma","display_name":"relapsed/refractory multiple myeloma","score":0.9900000095367432},{"id":"https://openalex.org/keywords/t-cell-exhaustion","display_name":"T cell exhaustion","score":0.953000009059906},{"id":"https://openalex.org/keywords/minimal-residual-disease-negativity","display_name":"minimal residual disease negativity","score":0.6779999732971191},{"id":"https://openalex.org/keywords/bispecific-antibodies","display_name":"bispecific antibodies","score":0.718999981880188},{"id":"https://openalex.org/keywords/teclistamab","display_name":"teclistamab","score":0.9599999785423279},{"id":"https://openalex.org/keywords/talquetamab","display_name":"talquetamab","score":0.9980000257492065},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.7630000114440918},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.375},{"id":"https://openalex.org/keywords/treatment-sequencing","display_name":"treatment sequencing","score":0.4300000071525574},{"id":"https://openalex.org/keywords/antigen-escape","display_name":"antigen escape","score":0.5120000243186951},{"id":"https://openalex.org/keywords/salvage-therapy","display_name":"salvage therapy","score":0.3149999976158142}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9731000065803528},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.597100019454956},{"id":"https://openalex.org/C104304963","wikidata":"https://www.wikidata.org/wiki/Q5316114","display_name":"Durability","level":2,"score":0.43369999527931213},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.36399999260902405},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.337799996137619},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2678999900817871},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.2630000114440918},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.2599000036716461},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.2551000118255615},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.24629999697208405}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s2152-2650(26)02878-8","doi":"https://doi.org/10.1016/s2152-2650(26)02878-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s2152-2650(26)02878-8","pdf_url":null,"source":{"id":"https://openalex.org/S186546955","display_name":"Clinical Lymphoma Myeloma & Leukemia","issn_l":"2152-2650","issn":["2152-2650","2152-2669"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lymphoma Myeloma and Leukemia","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4410439485","https://openalex.org/W4310109070","https://openalex.org/W3161917628","https://openalex.org/W4310159700","https://openalex.org/W7204689092","https://openalex.org/W4393093064","https://openalex.org/W4403659706","https://openalex.org/W7204717643","https://openalex.org/W2985772079","https://openalex.org/W4386278565"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2026-08-31T00:00:00"}