{"id":"https://openalex.org/W7204722707","doi":"https://doi.org/10.1016/s2152-2650(26)00478-7","title":"POSTER: AML-377: Lineage-Specific CK2\u03b1Deletion Reshapes the Transcriptome of Hematopoietic Stem Cells Toward an Immune-Primed State","display_name":"POSTER: AML-377: Lineage-Specific CK2\u03b1Deletion Reshapes the Transcriptome of Hematopoietic Stem Cells Toward an Immune-Primed State","publication_year":2026,"publication_date":"2026-08-01","ids":{"openalex":"https://openalex.org/W7204722707","doi":"https://doi.org/10.1016/s2152-2650(26)00478-7"},"language":"en","primary_location":{"id":"doi:10.1016/s2152-2650(26)00478-7","doi":"https://doi.org/10.1016/s2152-2650(26)00478-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s2152-2650(26)00478-7","pdf_url":null,"source":{"id":"https://openalex.org/S186546955","display_name":"Clinical Lymphoma Myeloma & Leukemia","issn_l":"2152-2650","issn":["2152-2650","2152-2669"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lymphoma Myeloma and Leukemia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5118614686","display_name":"Hannah Valensi","orcid":"https://orcid.org/0009-0008-4299-5903","observed_orcids":["https://orcid.org/0009-0008-4299-5903"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hannah Valensi","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019024840","display_name":"Rajesh Rajaiah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rajesh Rajaiah","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002551163","display_name":"Upendarrao Golla","orcid":"https://orcid.org/0000-0003-0519-7087","observed_orcids":["https://orcid.org/0000-0003-0519-7087"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Upendar Golla","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118614685","display_name":"Marudhu Pandiyan Shanmugam","orcid":"https://orcid.org/0000-0002-5217-2950","observed_orcids":["https://orcid.org/0000-0002-5217-2950"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marudhu Shanmugam","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093720922","display_name":"Anush Karampuri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anush Karampuri","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018474172","display_name":"Katherine Mercer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine Mercer","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072518893","display_name":"Sinisa Dovat","orcid":"https://orcid.org/0000-0003-3906-6165","observed_orcids":["https://orcid.org/0000-0003-3906-6165"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sinisa Dovat","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112606782","display_name":"Chandrika S. Gowda","orcid":"https://orcid.org/0000-0003-4582-820X","observed_orcids":["https://orcid.org/0000-0003-4582-820X"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chandrika Gowda","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079567652","display_name":"Yasin Uzun","orcid":"https://orcid.org/0000-0003-3478-3499","observed_orcids":["https://orcid.org/0000-0003-3478-3499"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yasin Uzun","raw_affiliation_strings":["Penn State College of Medicine, Hershey, PA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State College of Medicine, Hershey, PA, United States of America","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.62140218,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":null,"first_page":"S217","last_page":"S217"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.5390999913215637,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.5390999913215637,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.44020000100135803,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11215","display_name":"Chronic Myeloid Leukemia Treatments","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hematopoietic-stem-cells","display_name":"hematopoietic stem cells","score":0.8389999866485596},{"id":"https://openalex.org/keywords/transcriptome","display_name":"transcriptome","score":0.7710000276565552},{"id":"https://openalex.org/keywords/immune-priming","display_name":"immune priming","score":0.8640000224113464},{"id":"https://openalex.org/keywords/casein-kinase-2","display_name":"casein kinase 2","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.8913999795913696},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.6980999708175659},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6628000140190125},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6585000157356262},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.555400013923645},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.40689998865127563},{"id":"https://openalex.org/C2778086970","wikidata":"https://www.wikidata.org/wiki/Q514525","display_name":"Hematopoietic stem cell","level":4,"score":0.3384000062942505},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.2921000123023987},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2632000148296356},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.2597000002861023},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25200000405311584}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s2152-2650(26)00478-7","doi":"https://doi.org/10.1016/s2152-2650(26)00478-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s2152-2650(26)00478-7","pdf_url":null,"source":{"id":"https://openalex.org/S186546955","display_name":"Clinical Lymphoma Myeloma & Leukemia","issn_l":"2152-2650","issn":["2152-2650","2152-2669"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lymphoma Myeloma and Leukemia","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7204710954","https://openalex.org/W7154492349","https://openalex.org/W4386277482","https://openalex.org/W4413781453","https://openalex.org/W7204702559","https://openalex.org/W4413776770","https://openalex.org/W4386269908","https://openalex.org/W7204690926","https://openalex.org/W4413791142","https://openalex.org/W4205997202"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-08-31T00:00:00"}