{"id":"https://openalex.org/W7204721111","doi":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","title":"Counter effects of N. Sativa L. and P. ovata L. on indicative markers of non alcoholic fatty liver disease","display_name":"Counter effects of N. Sativa L. and P. ovata L. on indicative markers of non alcoholic fatty liver disease","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W7204721111","doi":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","mag":"2409304925","pmid":"https://pubmed.ncbi.nlm.nih.gov/26826811"},"language":"en","primary_location":{"id":"doi:10.36721/pjps/29/1/01.01.2016/2668/185-191","doi":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","is_oa":true,"landing_page_url":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","pdf_url":"https://pjps.pk/uploads/pdfs/29/1/Paper-26.pdf","source":{"id":"https://openalex.org/S24112332","display_name":"Pakistan Journal of Pharmaceutical Sciences","issn_l":"1011-601X","issn":["1011-601X","3105-9686"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319291","host_organization_name":"University of Karachi","host_organization_lineage":["https://openalex.org/P4310319291"],"host_organization_lineage_names":["University of Karachi"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pakistan Journal of Pharmaceutical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://pjps.pk/uploads/pdfs/29/1/Paper-26.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009995966","display_name":"Afshan Syed Abbas","orcid":"https://orcid.org/0000-0002-1062-6918","observed_orcids":["https://orcid.org/0000-0002-1062-6918"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Afshan Syed Abbas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5009995966"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3857,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.63503685,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"29","issue":"1","first_page":"185","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.6166999936103821,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.6166999936103821,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12750","display_name":"Nigella sativa pharmacological applications","score":0.36500000953674316,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9879999756813049},{"id":"https://openalex.org/keywords/nigella-sativa","display_name":"Nigella sativa","score":0.9909999966621399},{"id":"https://openalex.org/keywords/plantago-ovata","display_name":"Plantago ovata","score":0.921999990940094},{"id":"https://openalex.org/keywords/high-fat-high-sugar-diet","display_name":"high-fat high-sugar diet","score":0.6690000295639038},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.37299999594688416},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.9229999780654907},{"id":"https://openalex.org/keywords/hematology","display_name":"hematology","score":0.8119999766349792},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.5109999775886536}],"concepts":[{"id":"https://openalex.org/C2780658084","wikidata":"https://www.wikidata.org/wiki/Q311228","display_name":"Plantago ovata","level":2,"score":0.7472000122070312},{"id":"https://openalex.org/C2993714443","wikidata":"https://www.wikidata.org/wiki/Q160575","display_name":"Nigella sativa","level":2,"score":0.6773999929428101},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.6107000112533569},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5339999794960022},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.41449999809265137},{"id":"https://openalex.org/C2780655333","wikidata":"https://www.wikidata.org/wiki/Q333203","display_name":"Weaning","level":2,"score":0.4131999909877777},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4083000123500824},{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.4032000005245209},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.39309999346733093},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.38029998540878296},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.364300012588501},{"id":"https://openalex.org/C2778597767","wikidata":"https://www.wikidata.org/wiki/Q4027534","display_name":"Sucrose","level":2,"score":0.34459999203681946},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3441999852657318},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3199999928474426},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.30379998683929443},{"id":"https://openalex.org/C3019468659","wikidata":"https://www.wikidata.org/wiki/Q7988517","display_name":"Western diet","level":3,"score":0.2994999885559082},{"id":"https://openalex.org/C180260311","wikidata":"https://www.wikidata.org/wiki/Q1423543","display_name":"Animal fat","level":2,"score":0.29319998621940613},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2741999924182892},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2671000063419342},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.2549000084400177},{"id":"https://openalex.org/C2908578062","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Liver steatosis","level":4,"score":0.25429999828338623},{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.25270000100135803}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008517","descriptor_name":"Phytotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010943","descriptor_name":"Plantago","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031881","descriptor_name":"Nigella sativa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.36721/pjps/29/1/01.01.2016/2668/185-191","doi":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","is_oa":true,"landing_page_url":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","pdf_url":"https://pjps.pk/uploads/pdfs/29/1/Paper-26.pdf","source":{"id":"https://openalex.org/S24112332","display_name":"Pakistan Journal of Pharmaceutical Sciences","issn_l":"1011-601X","issn":["1011-601X","3105-9686"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319291","host_organization_name":"University of Karachi","host_organization_lineage":["https://openalex.org/P4310319291"],"host_organization_lineage_names":["University of Karachi"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pakistan Journal of Pharmaceutical Sciences","raw_type":"journal-article"},{"id":"pmid:26826811","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26826811","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pakistan journal of pharmaceutical sciences","raw_type":"Journal Article"},{"id":"mag:2409304925","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26826811","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"doi:10.36721/pjps/29/1/01.01.2016/2668/185-191","doi":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","is_oa":true,"landing_page_url":"https://doi.org/10.36721/pjps/29/1/01.01.2016/2668/185-191","pdf_url":"https://pjps.pk/uploads/pdfs/29/1/Paper-26.pdf","source":{"id":"https://openalex.org/S24112332","display_name":"Pakistan Journal of Pharmaceutical Sciences","issn_l":"1011-601X","issn":["1011-601X","3105-9686"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319291","host_organization_name":"University of Karachi","host_organization_lineage":["https://openalex.org/P4310319291"],"host_organization_lineage_names":["University of Karachi"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pakistan Journal of Pharmaceutical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"},{"score":0.4359000027179718,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204721111.pdf","grobid_xml":"https://content.openalex.org/works/W7204721111.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W117772421","https://openalex.org/W132311047","https://openalex.org/W163213204","https://openalex.org/W177349530","https://openalex.org/W266301326","https://openalex.org/W1555047677","https://openalex.org/W1583121859","https://openalex.org/W1976173209","https://openalex.org/W1979872889","https://openalex.org/W1996559225","https://openalex.org/W1999392081","https://openalex.org/W2006292992","https://openalex.org/W2006987310","https://openalex.org/W2008053664","https://openalex.org/W2008589923","https://openalex.org/W2009643755","https://openalex.org/W2010447489","https://openalex.org/W2016903551","https://openalex.org/W2021155912","https://openalex.org/W2023390659","https://openalex.org/W2042780225","https://openalex.org/W2050385934","https://openalex.org/W2054026627","https://openalex.org/W2059968618","https://openalex.org/W2065788317","https://openalex.org/W2087387943","https://openalex.org/W2088798319","https://openalex.org/W2092404774","https://openalex.org/W2096695647","https://openalex.org/W2101575401","https://openalex.org/W2114168045","https://openalex.org/W2120177716","https://openalex.org/W2123157804","https://openalex.org/W2130384982","https://openalex.org/W2134391068","https://openalex.org/W2136029777","https://openalex.org/W2148228584","https://openalex.org/W2271615776","https://openalex.org/W2274083858","https://openalex.org/W2278593945","https://openalex.org/W2412334477","https://openalex.org/W2412692540","https://openalex.org/W2416138573","https://openalex.org/W2473893536"],"related_works":["https://openalex.org/W2409304925","https://openalex.org/W2329127574","https://openalex.org/W2098883882","https://openalex.org/W2331816395","https://openalex.org/W4312116987","https://openalex.org/W2329228944","https://openalex.org/W2749169076","https://openalex.org/W3136484015","https://openalex.org/W2972459174","https://openalex.org/W4282980333"],"abstract_inverted_index":{"The":[0,94],"broad":[1],"spectrum":[2],"of":[3,24,77,92,96,176],"non-alcoholic":[4],"fatty":[5],"liver":[6,13],"disease":[7],"(NAFLD)":[8],"diseases":[9],"ranges":[10],"from":[11],"simple":[12],"inflammation":[14],"to":[15,18],"steatosis,":[16],"leading":[17],"fibrosis":[19],"and":[20,35,79,99,124,135],"cirrhosis.":[21],"Four":[22],"groups":[23,142],"weaning":[25],"(30g)":[26],"Rattus":[27],"norvegicus":[28],"were":[29,105,137],"designated":[30],"as":[31,172,174],"W-0,":[32],"W-I,":[33],"W-II":[34,67],"W-III.":[36],"For":[37],"sixteen":[38],"weeks":[39],"group":[40,47,66,80],"W-0":[41],"was":[42,68,82],"given":[43],"standard":[44],"pallet":[45,62],"diet,":[46],"I":[48],"consumed":[49],"diet":[50,63,71,85,156,177],"\"A\"":[51],"(20%":[52],"fat":[53,163],"Sucrose":[54],"+":[55,59],"33%":[56],"tea":[57],"whitener":[58],"34%":[60],"ground":[61],"+13%":[64],"water),":[65],"fed":[69],"on":[70,169],"\"B\"":[72],"(50g":[73,87],"Nigella":[74],"sativa":[75],"seeds/kg":[76],"A)":[78],"W-III":[81],"provided":[83],"with":[84,145],"\"C\"":[86],"Plantago":[88],"ovata":[89],"husks":[90],"/Kg":[91],"A).":[93],"analysis":[95],"CBC,":[97],"LFTs,":[98],"Lipid":[100],"profile":[101],"revealed":[102],"that":[103,154],"there":[104],"highly":[106],"significant":[107,126],"changes":[108],"(P<0.001)":[109],"in":[110,129,139,180],"the":[111,125,140,159,170],"MCV,":[112],"PLT,":[113],"Hb,":[114],"MCH,":[115],"MCHC,":[116],"RBC,":[117],"RDW%,":[118],"WBC,":[119],"MPV,":[120],"Triglycerides,":[121],"cholesterol,":[122],"LDL":[123],"alterations":[127],"(P<0.01)":[128],"albumin,":[130],"AST,":[131],"bilirubin,":[132],"AST/ALT,":[133],"HDL":[134],"cholesterol/HDL":[136],"observed":[138],"experimental":[141],"when":[143],"compared":[144],"control":[146],"by":[147],"using":[148],"one":[149],"way":[150],"ANOVA.":[151],"We":[152],"concluded":[153],"high-energy":[155],"can":[157],"alter":[158],"blood":[160],"profile.":[161],"Moreover":[162],"plummeting":[164],"agents":[165],"have":[166],"counter":[167],"impact":[168],"hematology":[171],"well":[173],"serology":[175],"induced":[178],"NAFLD":[179],"R.":[181],"norvegicus.":[182]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-08-31T00:00:00"}