{"id":"https://openalex.org/W7204698011","doi":"https://doi.org/10.1016/s2152-2650(26)01983-x","title":"AML-1587: Survival Benefit of FLT3 Inhibitor Maintenance After Allo-HSCT in FLT3-ITD AML: A Systematic Review and Reconstructed Individual Patient Data Meta-Analysis of Randomized Controlled Trials","display_name":"AML-1587: Survival Benefit of FLT3 Inhibitor Maintenance After Allo-HSCT in FLT3-ITD AML: A Systematic Review and Reconstructed Individual Patient Data Meta-Analysis of Randomized Controlled Trials","publication_year":2026,"publication_date":"2026-08-01","ids":{"openalex":"https://openalex.org/W7204698011","doi":"https://doi.org/10.1016/s2152-2650(26)01983-x"},"language":"en","primary_location":{"id":"doi:10.1016/s2152-2650(26)01983-x","doi":"https://doi.org/10.1016/s2152-2650(26)01983-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s2152-2650(26)01983-x","pdf_url":null,"source":{"id":"https://openalex.org/S186546955","display_name":"Clinical Lymphoma Myeloma & Leukemia","issn_l":"2152-2669","issn":["2152-2669","2152-2650"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lymphoma Myeloma and Leukemia","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7204698011"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120586645","display_name":"Sahithi Mani Chandana Paramkusam","orcid":"https://orcid.org/0009-0002-5747-471X","observed_orcids":["https://orcid.org/0009-0002-5747-471X"]},"institutions":[{"id":"https://openalex.org/I179150554","display_name":"Guntur Medical College","ror":"https://ror.org/02evmt624","country_code":"IN","type":"education","lineage":["https://openalex.org/I179150554"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sahithi MC Paramkusam","raw_affiliation_strings":["Katuri Medical College and Hospital, Guntur, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Katuri Medical College and Hospital, Guntur, India","institution_ids":["https://openalex.org/I179150554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122741859","display_name":"Abhinav Vardhan Paramkusam","orcid":"https://orcid.org/0009-0006-1968-3114","observed_orcids":["https://orcid.org/0009-0006-1968-3114"]},"institutions":[{"id":"https://openalex.org/I2799614505","display_name":"University of Perpetual Help System DALTA","ror":"https://ror.org/05vx7wd63","country_code":"PH","type":"education","lineage":["https://openalex.org/I2799614505"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Abhinav V Paramkusam","raw_affiliation_strings":["Jonelta Foundation School of Medicine\u2013UPHSD, Las Pinas, Philippines"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jonelta Foundation School of Medicine\u2013UPHSD, Las Pinas, Philippines","institution_ids":["https://openalex.org/I2799614505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114170979","display_name":"Mehak Dang","orcid":"https://orcid.org/0000-0002-6762-8930","observed_orcids":["https://orcid.org/0000-0002-6762-8930"]},"institutions":[{"id":"https://openalex.org/I86826812","display_name":"JSS Medical College and Hospital","ror":"https://ror.org/02xf0fd83","country_code":"IN","type":"education","lineage":["https://openalex.org/I86826812"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mehak Dang","raw_affiliation_strings":["JSS Medical College, Mysore, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"JSS Medical College, Mysore, India","institution_ids":["https://openalex.org/I86826812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035085460","display_name":"Sravani Bhavanam","orcid":"https://orcid.org/0009-0005-8929-052X","observed_orcids":["https://orcid.org/0009-0005-8929-052X"]},"institutions":[{"id":"https://openalex.org/I2802707398","display_name":"Brookdale University Hospital and Medical Center","ror":"https://ror.org/0065vkd37","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802707398"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sravani Bhavanam","raw_affiliation_strings":["Brookdale University Hospital and MedicalCenter, Brooklyn, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brookdale University Hospital and MedicalCenter, Brooklyn, NY, USA","institution_ids":["https://openalex.org/I2802707398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099066963","display_name":"Sameer Kumar Majety","orcid":"https://orcid.org/0009-0008-6877-6303","observed_orcids":["https://orcid.org/0009-0008-6877-6303"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sameer Kumar Majety","raw_affiliation_strings":["HCACenter Point MedicalCenter, Kansas City, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HCACenter Point MedicalCenter, Kansas City, MO, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148653168","display_name":"Sushmitha Venkata Annadatha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799614505","display_name":"University of Perpetual Help System DALTA","ror":"https://ror.org/05vx7wd63","country_code":"PH","type":"education","lineage":["https://openalex.org/I2799614505"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Sushmitha Venkata Annadatha","raw_affiliation_strings":["Jonelta Foundation School of Medicine\u2013UPHSD, Las Pinas, Philippines"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jonelta Foundation School of Medicine\u2013UPHSD, Las Pinas, Philippines","institution_ids":["https://openalex.org/I2799614505"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029641201","display_name":"Fahad Alabbas","orcid":"https://orcid.org/0000-0001-6910-1369","observed_orcids":["https://orcid.org/0000-0001-6910-1369"]},"institutions":[{"id":"https://openalex.org/I1335369389","display_name":"Riyadh Armed Forces Hospital","ror":"https://ror.org/00mtny680","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I1335369389"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Fahad Alabbas","raw_affiliation_strings":["Prince Sultan Military Medical City, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Prince Sultan Military Medical City, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I1335369389"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":null,"first_page":"S574","last_page":"S575"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flt3-itd-acute-myeloid-leukemia","display_name":"FLT3-ITD acute myeloid leukemia","score":0.9279999732971191},{"id":"https://openalex.org/keywords/allogeneic-hematopoietic-stem-cell-transplantation","display_name":"allogeneic hematopoietic stem cell transplantation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/relapse-free-survival","display_name":"relapse-free survival","score":0.8240000009536743},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":1.0},{"id":"https://openalex.org/keywords/sorafenib","display_name":"sorafenib","score":0.9039999842643738},{"id":"https://openalex.org/keywords/midostaurin","display_name":"midostaurin","score":1.0},{"id":"https://openalex.org/keywords/gilteritinib","display_name":"gilteritinib","score":1.0},{"id":"https://openalex.org/keywords/post-transplant-recurrence","display_name":"post-transplant relapse","score":0.6480000019073486},{"id":"https://openalex.org/keywords/restricted-mean-survival-time","display_name":"restricted mean survival time","score":0.7689999938011169},{"id":"https://openalex.org/keywords/landmark-analysis","display_name":"landmark analysis","score":0.527999997138977},{"id":"https://openalex.org/keywords/complete-remission","display_name":"complete remission","score":0.5289999842643738},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9649999737739563},{"id":"https://openalex.org/C3018822202","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Patient data","level":2,"score":0.6244000196456909},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5530999898910522},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49880000948905945},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4887999892234802},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.43860000371932983},{"id":"https://openalex.org/C3020493868","wikidata":"https://www.wikidata.org/wiki/Q55631277","display_name":"Real world data","level":2,"score":0.3573000133037567},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.3515999913215637},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3391000032424927},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.2736999988555908}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s2152-2650(26)01983-x","doi":"https://doi.org/10.1016/s2152-2650(26)01983-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s2152-2650(26)01983-x","pdf_url":null,"source":{"id":"https://openalex.org/S186546955","display_name":"Clinical Lymphoma Myeloma & Leukemia","issn_l":"2152-2669","issn":["2152-2669","2152-2650"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lymphoma Myeloma and Leukemia","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4410807957","https://openalex.org/W4405043407","https://openalex.org/W4309659620","https://openalex.org/W7133950445","https://openalex.org/W7108722598","https://openalex.org/W4405035123","https://openalex.org/W4410945389","https://openalex.org/W4399353522","https://openalex.org/W4417019060","https://openalex.org/W7204693800"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-08-31T00:00:00"}