{"id":"https://openalex.org/W7204684256","doi":"https://doi.org/10.3390/ijerph23091127","title":"Prevalence of Hepatic and Splenic Melioidosis: A Systematic Review and Meta-Analysis","display_name":"Prevalence of Hepatic and Splenic Melioidosis: A Systematic Review and Meta-Analysis","publication_year":2026,"publication_date":"2026-08-29","ids":{"openalex":"https://openalex.org/W7204684256","doi":"https://doi.org/10.3390/ijerph23091127"},"language":"en","primary_location":{"id":"doi:10.3390/ijerph23091127","doi":"https://doi.org/10.3390/ijerph23091127","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijerph23091127","pdf_url":null,"source":{"id":"https://openalex.org/S15239247","display_name":"International Journal of Environmental Research and Public Health","issn_l":"1660-4601","issn":["1660-4601","1661-7827"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","erih-plus","medline","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Environmental Research and Public Health","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/ijerph23091127","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003796138","display_name":"Jongkonnee Thanasai","orcid":"https://orcid.org/0009-0004-4542-8980","observed_orcids":["https://orcid.org/0009-0004-4542-8980"]},"institutions":[{"id":"https://openalex.org/I123096312","display_name":"Mahasarakham University","ror":"https://ror.org/0453j3c58","country_code":"TH","type":"education","lineage":["https://openalex.org/I123096312"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Jongkonnee Thanasai","raw_affiliation_strings":["Faculty of Medicine, Mahasarakham University, Mahasarakham 44000, Thailand"],"raw_orcid":"https://orcid.org/0009-0004-4542-8980","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Mahasarakham University, Mahasarakham 44000, Thailand","institution_ids":["https://openalex.org/I123096312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067988584","display_name":"Anchalee Chittamma","orcid":"https://orcid.org/0000-0003-0075-6548","observed_orcids":["https://orcid.org/0000-0003-0075-6548"]},"institutions":[{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]},{"id":"https://openalex.org/I4210140007","display_name":"Ramathibodi Hospital","ror":"https://ror.org/04884sy85","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4210140007"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Anchalee Chittamma","raw_affiliation_strings":["Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084876706","display_name":"Supphachoke Khemla","orcid":"https://orcid.org/0009-0001-7490-522X","observed_orcids":["https://orcid.org/0009-0001-7490-522X"]},"institutions":[{"id":"https://openalex.org/I4405277321","display_name":"Nakhon Phanom Hospital","ror":"https://ror.org/029749q06","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4405277321"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Supphachoke Khemla","raw_affiliation_strings":["Division of Infectious Diseases, Department of Internal Medicine, Nakhon Phanom Hospital, Nakhon Phanom 48000, Thailand"],"raw_orcid":"https://orcid.org/0009-0001-7490-522X","affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases, Department of Internal Medicine, Nakhon Phanom Hospital, Nakhon Phanom 48000, Thailand","institution_ids":["https://openalex.org/I4405277321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070239277","display_name":"Atthaphong Phongphithakchai","orcid":"https://orcid.org/0000-0001-8422-2644","observed_orcids":["https://orcid.org/0000-0001-8422-2644"]},"institutions":[{"id":"https://openalex.org/I131868736","display_name":"Prince of Songkla University","ror":"https://ror.org/0575ycz84","country_code":"TH","type":"education","lineage":["https://openalex.org/I131868736"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Atthaphong Phongphithakchai","raw_affiliation_strings":["Nephrology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand"],"raw_orcid":"https://orcid.org/0000-0001-8422-2644","affiliations":[{"raw_affiliation_string":"Nephrology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand","institution_ids":["https://openalex.org/I131868736"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042972287","display_name":"Moragot Chatatikun","orcid":"https://orcid.org/0000-0003-3264-1155","observed_orcids":["https://orcid.org/0000-0003-3264-1155"]},"institutions":[{"id":"https://openalex.org/I117277806","display_name":"Nakhon Phanom University","ror":"https://ror.org/03j999y97","country_code":"TH","type":"education","lineage":["https://openalex.org/I117277806"]},{"id":"https://openalex.org/I96916377","display_name":"Walailak University","ror":"https://ror.org/04b69g067","country_code":"TH","type":"education","lineage":["https://openalex.org/I96916377"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Moragot Chatatikun","raw_affiliation_strings":["Medical Technology Program, Faculty of Science, Nakhon Phanom University, Nakhon Phanom 48000, Thailand","School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand"],"raw_orcid":"https://orcid.org/0000-0003-3264-1155","affiliations":[{"raw_affiliation_string":"Medical Technology Program, Faculty of Science, Nakhon Phanom University, Nakhon Phanom 48000, Thailand","institution_ids":["https://openalex.org/I117277806"]},{"raw_affiliation_string":"School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand","institution_ids":["https://openalex.org/I96916377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086257683","display_name":"Jitbanjong Tangpong","orcid":"https://orcid.org/0000-0002-4768-7829","observed_orcids":["https://orcid.org/0000-0002-4768-7829"]},"institutions":[{"id":"https://openalex.org/I96916377","display_name":"Walailak University","ror":"https://ror.org/04b69g067","country_code":"TH","type":"education","lineage":["https://openalex.org/I96916377"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Jitbanjong Tangpong","raw_affiliation_strings":["School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand"],"raw_orcid":"https://orcid.org/0000-0002-4768-7829","affiliations":[{"raw_affiliation_string":"School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand","institution_ids":["https://openalex.org/I96916377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004427858","display_name":"Sa-ngob Laklaeng","orcid":"https://orcid.org/0009-0003-9312-903X","observed_orcids":["https://orcid.org/0009-0003-9312-903X"]},"institutions":[{"id":"https://openalex.org/I96916377","display_name":"Walailak University","ror":"https://ror.org/04b69g067","country_code":"TH","type":"education","lineage":["https://openalex.org/I96916377"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sa-ngob Laklaeng","raw_affiliation_strings":["School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand","institution_ids":["https://openalex.org/I96916377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148707784","display_name":"Jirart Songsri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96916377","display_name":"Walailak University","ror":"https://ror.org/04b69g067","country_code":"TH","type":"education","lineage":["https://openalex.org/I96916377"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Jirart Songsri","raw_affiliation_strings":["School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand","institution_ids":["https://openalex.org/I96916377"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029232929","display_name":"Wiyada Kwanhian Klangbud","orcid":"https://orcid.org/0000-0002-5247-166X","observed_orcids":["https://orcid.org/0000-0002-5247-166X"]},"institutions":[{"id":"https://openalex.org/I117277806","display_name":"Nakhon Phanom University","ror":"https://ror.org/03j999y97","country_code":"TH","type":"education","lineage":["https://openalex.org/I117277806"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Wiyada Kwanhian Klangbud","raw_affiliation_strings":["Faculty of Medicine, Nakhon Phanom University, Nakhon Phanom 48000, Thailand","Medical Technology Program, Faculty of Science, Nakhon Phanom University, Nakhon Phanom 48000, Thailand"],"raw_orcid":"https://orcid.org/0000-0002-5247-166X","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Nakhon Phanom University, Nakhon Phanom 48000, Thailand","institution_ids":["https://openalex.org/I117277806"]},{"raw_affiliation_string":"Medical Technology Program, Faculty of Science, Nakhon Phanom University, Nakhon Phanom 48000, Thailand","institution_ids":["https://openalex.org/I117277806"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5029232929"],"corresponding_institution_ids":["https://openalex.org/I117277806"],"apc_list":{"value":2500,"currency":"CHF","value_usd":3016},"apc_paid":{"value":2500,"currency":"CHF","value_usd":3016},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":"9","first_page":"1127","last_page":"1127"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12951","display_name":"Burkholderia infections and melioidosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12951","display_name":"Burkholderia infections and melioidosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11899","display_name":"Brucella: diagnosis, epidemiology, treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melioidosis","display_name":"melioidosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/burkholderia-pseudomallei","display_name":"Burkholderia pseudomallei","score":0.9959999918937683},{"id":"https://openalex.org/keywords/liver-involvement","display_name":"liver involvement","score":0.9039999842643738},{"id":"https://openalex.org/keywords/splenic-involvement","display_name":"splenic involvement","score":1.0},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6050000190734863},{"id":"https://openalex.org/keywords/visceral-involvement","display_name":"visceral involvement","score":0.5860000252723694},{"id":"https://openalex.org/keywords/abdominal-imaging","display_name":"abdominal imaging","score":0.7770000100135803},{"id":"https://openalex.org/keywords/southeast-asia","display_name":"Southeast Asia","score":0.7770000100135803},{"id":"https://openalex.org/keywords/oceania","display_name":"Oceania","score":0.9769999980926514},{"id":"https://openalex.org/keywords/endemic-areas","display_name":"endemic areas","score":0.7480000257492065},{"id":"https://openalex.org/keywords/early-diagnosis-and-treatment","display_name":"early diagnosis and treatment","score":0.4580000042915344},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.4390000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8140000104904175},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6951000094413757},{"id":"https://openalex.org/C2779775996","wikidata":"https://www.wikidata.org/wiki/Q963944","display_name":"Melioidosis","level":2,"score":0.6908000111579895},{"id":"https://openalex.org/C2779384505","wikidata":"https://www.wikidata.org/wiki/Q17007513","display_name":"Concomitant","level":2,"score":0.6787999868392944},{"id":"https://openalex.org/C2779110727","wikidata":"https://www.wikidata.org/wiki/Q140475","display_name":"Burkholderia pseudomallei","level":3,"score":0.5490999817848206},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.49630001187324524},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4875999987125397},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.4747999906539917},{"id":"https://openalex.org/C152541439","wikidata":"https://www.wikidata.org/wiki/Q5186693","display_name":"Critical appraisal","level":3,"score":0.439300000667572},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4244000017642975},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.4162999987602234},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.36480000615119934},{"id":"https://openalex.org/C2776619665","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Splenic disease","level":4,"score":0.3582000136375427},{"id":"https://openalex.org/C187960798","wikidata":"https://www.wikidata.org/wiki/Q7631152","display_name":"Subgroup analysis","level":3,"score":0.31949999928474426},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.30410000681877136},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.2957000136375427},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.2937999963760376},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.29109999537467957},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.2700999975204468},{"id":"https://openalex.org/C186079640","wikidata":"https://www.wikidata.org/wiki/Q719602","display_name":"Prevalence","level":3,"score":0.25600001215934753}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/ijerph23091127","doi":"https://doi.org/10.3390/ijerph23091127","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijerph23091127","pdf_url":null,"source":{"id":"https://openalex.org/S15239247","display_name":"International Journal of Environmental Research and Public Health","issn_l":"1660-4601","issn":["1660-4601","1661-7827"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","erih-plus","medline","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Environmental Research and Public Health","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/ijerph23091127","doi":"https://doi.org/10.3390/ijerph23091127","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijerph23091127","pdf_url":null,"source":{"id":"https://openalex.org/S15239247","display_name":"International Journal of Environmental Research and Public Health","issn_l":"1660-4601","issn":["1660-4601","1661-7827"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","erih-plus","medline","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Environmental Research and Public Health","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320324290","display_name":"Mahasarakham University","ror":"https://ror.org/0453j3c58"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W2056048232","https://openalex.org/W2107966948","https://openalex.org/W2130623712","https://openalex.org/W2136270214","https://openalex.org/W2151360409","https://openalex.org/W2167191881","https://openalex.org/W2236183420","https://openalex.org/W2316183985","https://openalex.org/W2417616971","https://openalex.org/W2467096262","https://openalex.org/W2888178490","https://openalex.org/W2919454126","https://openalex.org/W2965446755","https://openalex.org/W3029718119","https://openalex.org/W3196741559","https://openalex.org/W4211084778","https://openalex.org/W4407698194"],"related_works":["https://openalex.org/W7140193737","https://openalex.org/W4416229366","https://openalex.org/W7213400315","https://openalex.org/W7166436771","https://openalex.org/W3124553023","https://openalex.org/W3006155755","https://openalex.org/W2919454126","https://openalex.org/W4409292242","https://openalex.org/W4309713571","https://openalex.org/W7204444124"],"abstract_inverted_index":{"Background:":[0],"Melioidosis":[1],"is":[2,278],"a":[3,230],"potentially":[4],"life-threatening":[5],"infection":[6],"caused":[7],"by":[8],"Burkholderia":[9],"pseudomallei.":[10],"Hepatic":[11,251],"and":[12,28,38,49,64,114,164,185,197,209,235,252,265,327],"splenic":[13,84,154,186,218,248,253],"involvement":[14,52,85,145,155,167,187,219,254],"are":[15,255,321],"recognized":[16],"manifestations":[17,257],"of":[18,46,61,143,183,233,238,245,258,292,310,330],"disseminated":[19],"melioidosis;":[20],"however,":[21],"reported":[22],"prevalence":[23,45,100,142,182,325],"varies":[24],"considerably":[25],"across":[26],"studies,":[27],"no":[29,236],"quantitative":[30],"synthesis":[31],"has":[32],"been":[33],"available.":[34],"This":[35],"systematic":[36,59],"review":[37],"meta-analysis":[39],"aimed":[40],"to":[41,71,97,111,228,306,323],"estimate":[42,98],"the":[43,75,122,289],"pooled":[44,99,141,181],"hepatic,":[47],"splenic,":[48],"concomitant":[50,165],"hepatosplenic":[51,166,331],"in":[53,188,192,263,267,280,284,295,303],"patients":[54,87,135,296],"with":[55,88,101,136,297],"melioidosis.":[56,332],"Methods:":[57],"A":[58],"search":[60],"PubMed,":[62],"Embase,":[63],"Scopus":[65],"was":[66,119,146,156,168,241],"conducted":[67,109],"from":[68],"database":[69],"inception":[70],"May":[72],"2026,":[73],"following":[74],"PRISMA":[76],"2020":[77],"guidelines.":[78],"Observational":[79],"studies":[80,132,225,316],"reporting":[81],"hepatic":[82,144,184,213,246],"and/or":[83],"among":[86],"confirmed":[89,300],"melioidosis":[90,137],"were":[91,95,108,138,205,226],"eligible.":[92],"Random-effects":[93],"meta-analyses":[94],"performed":[96],"95%":[102],"confidence":[103],"intervals":[104],"(CIs).":[105],"Subgroup":[106,176],"analyses":[107,177,244],"according":[110],"geographic":[112,272],"region":[113],"age":[115],"group.":[116],"Methodological":[117],"quality":[118],"assessed":[120],"using":[121,317],"Joanna":[123],"Briggs":[124],"Institute":[125],"critical":[126],"appraisal":[127],"checklist.":[128],"Results:":[129],"Fourteen":[130],"eligible":[131],"involving":[133],"1844":[134],"included.":[139],"The":[140],"11%":[147],"(95%":[148,158,170],"CI,":[149,159,171],"6\u201318%;":[150],"I2":[151,161,173],"=":[152,162,174,195,199,215,221],"84.8%),":[153],"15%":[157],"7\u201327%;":[160],"95.8%),":[163],"13%":[169],"4\u201334%;":[172],"89.5%).":[175],"demonstrated":[178],"significantly":[179],"higher":[180],"Southeast":[189,281],"Asia":[190,282],"than":[191,283],"Oceania":[193],"(p":[194,214,220],"0.0164":[196],"p":[198],"0.0003,":[200],"respectively).":[201],"No":[202],"significant":[203],"differences":[204],"observed":[206],"between":[207],"adult":[208],"pediatric":[210],"populations":[211],"for":[212,243],"0.1607)":[216],"or":[217,247,299],"0.8243).":[222],"Most":[223],"included":[224],"judged":[227],"have":[229],"moderate":[231],"risk":[232],"bias,":[234],"evidence":[237],"small-study":[239],"effects":[240],"identified":[242],"involvement.":[249,312],"Conclusions:":[250],"common":[256],"melioidosis,":[259,301],"affecting":[260],"approximately":[261],"one":[262,266],"nine":[264],"seven":[268],"patients,":[269],"respectively.":[270],"Significant":[271],"variation":[273],"suggests":[274],"that":[275],"disease":[276],"burden":[277],"greater":[279],"Oceania.":[285],"These":[286],"findings":[287],"support":[288],"routine":[290],"consideration":[291],"abdominal":[293],"imaging":[294,319],"suspected":[298],"particularly":[302],"endemic":[304],"regions,":[305],"facilitate":[307],"early":[308],"recognition":[309],"visceral":[311],"Further":[313],"prospective":[314],"multicenter":[315],"standardized":[318],"protocols":[320],"needed":[322],"refine":[324],"estimates":[326],"improve":[328],"understanding":[329]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-08-31T00:00:00"}