{"id":"https://openalex.org/W7204658239","doi":"https://doi.org/10.1007/s10792-026-04219-z","title":"Home-based low-level light therapy using a commercial LED mask for dry eye disease","display_name":"Home-based low-level light therapy using a commercial LED mask for dry eye disease","publication_year":2026,"publication_date":"2026-08-29","ids":{"openalex":"https://openalex.org/W7204658239","doi":"https://doi.org/10.1007/s10792-026-04219-z","pmid":"https://pubmed.ncbi.nlm.nih.gov/42667448"},"language":"en","primary_location":{"id":"doi:10.1007/s10792-026-04219-z","doi":"https://doi.org/10.1007/s10792-026-04219-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10792-026-04219-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10792-026-04219-z.pdf","source":{"id":"https://openalex.org/S47727624","display_name":"International Ophthalmology","issn_l":"0165-5701","issn":["0165-5701","1573-2630"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s10792-026-04219-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033029574","display_name":"Luca Scuderi","orcid":"https://orcid.org/0000-0003-4725-6778","observed_orcids":["https://orcid.org/0000-0003-4725-6778"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Scuderi","raw_affiliation_strings":["Department of Sense Organs, University of Rome Sapienza, 00161, Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0003-4725-6778","affiliations":[{"raw_affiliation_string":"Department of Sense Organs, University of Rome Sapienza, 00161, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009105924","display_name":"Serena Fragiotta","orcid":"https://orcid.org/0000-0002-6214-6270","observed_orcids":["https://orcid.org/0000-0002-6214-6270"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Serena Fragiotta","raw_affiliation_strings":["Ophthalmology Unit, Neurosciences, Mental Health, and Sensory Organs (NESMOS) Department, Sapienza University of Rome, Via Di Grottarossa 1035/1039, 00189, Rome, Italy. serena.fragiotta@uniroma1.it"],"raw_orcid":"https://orcid.org/0000-0002-6214-6270","affiliations":[{"raw_affiliation_string":"Ophthalmology Unit, Neurosciences, Mental Health, and Sensory Organs (NESMOS) Department, Sapienza University of Rome, Via Di Grottarossa 1035/1039, 00189, Rome, Italy. serena.fragiotta@uniroma1.it","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013018278","display_name":"Chiara Ciancimino","orcid":"https://orcid.org/0000-0001-6600-0917","observed_orcids":["https://orcid.org/0000-0001-6600-0917"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara Ciancimino","raw_affiliation_strings":["Ophthalmology Unit, Neurosciences, Mental Health, and Sensory Organs (NESMOS) Department, Sapienza University of Rome, Via Di Grottarossa 1035/1039, 00189, Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0001-6600-0917","affiliations":[{"raw_affiliation_string":"Ophthalmology Unit, Neurosciences, Mental Health, and Sensory Organs (NESMOS) Department, Sapienza University of Rome, Via Di Grottarossa 1035/1039, 00189, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004162310","display_name":"Gianluca Scuderi","orcid":"https://orcid.org/0000-0003-0744-0722","observed_orcids":["https://orcid.org/0000-0003-0744-0722"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianluca Scuderi","raw_affiliation_strings":["Ophthalmology Unit, Neurosciences, Mental Health, and Sensory Organs (NESMOS) Department, Sapienza University of Rome, Via Di Grottarossa 1035/1039, 00189, Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0003-0744-0722","affiliations":[{"raw_affiliation_string":"Ophthalmology Unit, Neurosciences, Mental Health, and Sensory Organs (NESMOS) Department, Sapienza University of Rome, Via Di Grottarossa 1035/1039, 00189, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5009105924"],"corresponding_institution_ids":["https://openalex.org/I861853513"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":{"value":3790,"currency":"USD","value_usd":3790},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.70878061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dry-eye-disease","display_name":"dry eye","score":0.8970000147819519},{"id":"https://openalex.org/keywords/low-level-laser-therapy","display_name":"low-level laser therapy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/home-based-treatment","display_name":"home-based therapy","score":0.781000018119812},{"id":"https://openalex.org/keywords/meibography","display_name":"meibography","score":0.6740000247955322},{"id":"https://openalex.org/keywords/tear-osmolarity","display_name":"tear osmolarity","score":0.8830000162124634},{"id":"https://openalex.org/keywords/tear-film-break-up-time","display_name":"tear film break-up time","score":0.996999979019165},{"id":"https://openalex.org/keywords/ocular-surface-disease","display_name":"ocular surface disease","score":0.6380000114440918},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.9210000038146973},{"id":"https://openalex.org/keywords/corneal-fluorescein-staining","display_name":"corneal fluorescein staining","score":0.765999972820282},{"id":"https://openalex.org/keywords/schirmer-test","display_name":"Schirmer test","score":0.6690000295639038}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9686999917030334},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.7408999800682068},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.45559999346733093},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4510999917984009},{"id":"https://openalex.org/C2778837293","wikidata":"https://www.wikidata.org/wiki/Q3320636","display_name":"Artificial tears","level":2,"score":0.43799999356269836},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.3646000027656555},{"id":"https://openalex.org/C2778015030","wikidata":"https://www.wikidata.org/wiki/Q410922","display_name":"Fluorescein","level":3,"score":0.35830000042915344},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3513000011444092},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.3433000147342682},{"id":"https://openalex.org/C2778275304","wikidata":"https://www.wikidata.org/wiki/Q76469","display_name":"Tears","level":2,"score":0.32280001044273376},{"id":"https://openalex.org/C2992234860","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Eye care","level":2,"score":0.27709999680519104},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2603999972343445},{"id":"https://openalex.org/C3017636755","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Corneal disease","level":3,"score":0.2547000050544739},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.25200000405311584}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013666","descriptor_name":"Tears","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013666","descriptor_name":"Tears","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013666","descriptor_name":"Tears","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013666","descriptor_name":"Tears","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D015352","descriptor_name":"Dry Eye Syndromes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10792-026-04219-z","doi":"https://doi.org/10.1007/s10792-026-04219-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10792-026-04219-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10792-026-04219-z.pdf","source":{"id":"https://openalex.org/S47727624","display_name":"International Ophthalmology","issn_l":"0165-5701","issn":["0165-5701","1573-2630"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Ophthalmology","raw_type":"journal-article"},{"id":"pmid:42667448","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42667448","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International ophthalmology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13526077","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13526077/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Int Ophthalmol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s10792-026-04219-z","doi":"https://doi.org/10.1007/s10792-026-04219-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10792-026-04219-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10792-026-04219-z.pdf","source":{"id":"https://openalex.org/S47727624","display_name":"International Ophthalmology","issn_l":"0165-5701","issn":["0165-5701","1573-2630"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Ophthalmology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322510","display_name":"Sapienza Universit\u00e0 di Roma","ror":"https://ror.org/02be6w209"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204658239.pdf","grobid_xml":"https://content.openalex.org/works/W7204658239.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1921578580","https://openalex.org/W1978381243","https://openalex.org/W2037972678","https://openalex.org/W2091630088","https://openalex.org/W2154248482","https://openalex.org/W2414212658","https://openalex.org/W2475049721","https://openalex.org/W2644431637","https://openalex.org/W2737787547","https://openalex.org/W2738160893","https://openalex.org/W2991610295","https://openalex.org/W3012469448","https://openalex.org/W3013368019","https://openalex.org/W3169203763","https://openalex.org/W3203290004","https://openalex.org/W4200108240","https://openalex.org/W4211224529","https://openalex.org/W4214899040","https://openalex.org/W4285797225","https://openalex.org/W4296160951","https://openalex.org/W4307955599","https://openalex.org/W4310520190","https://openalex.org/W4310946330","https://openalex.org/W4362691951","https://openalex.org/W4362692575","https://openalex.org/W4386934964","https://openalex.org/W4387996821","https://openalex.org/W4401298034","https://openalex.org/W4403699689","https://openalex.org/W4411056344","https://openalex.org/W4413022320","https://openalex.org/W4416131685","https://openalex.org/W7140032730"],"related_works":[],"abstract_inverted_index":{"PURPOSE:":[0],"Light-based":[1],"therapies,":[2],"including":[3],"low-level":[4],"light":[5],"therapy":[6],"(LLLT),":[7],"have":[8],"recently":[9],"emerged":[10],"as":[11],"promising":[12],"non-invasive":[13],"approaches":[14],"for":[15,67,224],"dry":[16],"eye":[17],"disease":[18],"(DED).":[19],"This":[20,36,206],"study":[21,40,207],"evaluates":[22],"the":[23,58,91,110,129,183,193],"impact":[24],"of":[25],"a":[26,74,120,154,210],"consumer-grade":[27],"home-based":[28],"LED":[29,59,212],"Beauty":[30,60],"Mask":[31,61],"on":[32,70],"DED":[33,50,221],"parameters.":[34],"METHODS:":[35],"retrospective":[37],"observational":[38],"cohort":[39],"included":[41,95],"20":[42],"postmenopausal":[43],"women":[44],"(20":[45],"eyes)":[46],"diagnosed":[47],"with":[48,128],"moderate":[49],"and":[51,86,94,109,156,217,229],"MGD":[52],"who":[53],"underwent":[54],"cosmetic":[55,211],"treatment":[56,93],"using":[57],"Koled\u00ae.":[62],"The":[63],"device":[64],"was":[65],"used":[66],"20-min":[68],"sessions":[69],"alternate":[71],"days":[72],"over":[73,123],"3-week":[75],"period.":[76],"Clinical":[77],"evaluations":[78],"were":[79,165,203],"performed":[80],"at":[81,134,179],"baseline,":[82],"3":[83],"weeks":[84,88],"(T1),":[85],"2":[87],"(T2)":[89],"after":[90,196],"last":[92],"tear":[96,98],"osmolarity,":[97],"film":[99,137],"break-up":[100],"time":[101,124],"(TBUT),":[102],"Schirmer":[103,168],"I":[104,169],"test,":[105],"corneal":[106],"fluorescein":[107,176],"staining,":[108],"Ocular":[111],"Surface":[112],"Disease":[113],"Index":[114],"(OSDI).":[115],"RESULTS:":[116],"Tear":[117,136],"osmolarity":[118,190],"demonstrated":[119],"significant":[121,155,163],"improvement":[122,219],"(P":[125,145,159,172],"<":[126,160],"0.001),":[127],"most":[130],"pronounced":[131],"change":[132],"observed":[133,166],"T1.":[135],"stability,":[138],"assessed":[139],"by":[140,151,182,231],"TBUT,":[141],"also":[142],"improved":[143],"significantly":[144],"=":[146,173],"0.001).":[147,161],"Subjective":[148],"symptoms":[149],"measured":[150],"OSDI":[152],"showed":[153],"sustained":[157],"reduction":[158],"No":[162,198],"changes":[164],"in":[167,220],"test":[170],"values":[171,191],"0.29).":[174],"Corneal":[175],"staining":[177],"present":[178],"baseline":[180],"resolved":[181],"final":[184],"follow-up.":[185],"Four":[186],"eyes":[187],"(20%)":[188],"exhibited":[189],"below":[192],"measurable":[194],"range":[195],"treatment.":[197],"discomfort":[199],"or":[200],"adverse":[201],"events":[202],"reported.":[204],"CONCLUSIONS:":[205],"suggests":[208],"that":[209],"mask":[213],"may":[214],"provide":[215],"symptomatic":[216],"functional":[218],"when":[222],"repurposed":[223],"ocular":[225],"use.":[226],"Although":[227],"preliminary":[228],"limited":[230],"sample":[232],"size,":[233],"these":[234],"findings":[235],"support":[236],"further":[237],"investigation":[238],"through":[239],"controlled":[240],"clinical":[241],"trials.":[242]},"counts_by_year":[],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2026-08-30T00:00:00"}