{"id":"https://openalex.org/W7204656197","doi":"https://doi.org/10.64898/2026.08.25.747076","title":"Curvature-guided chiral collective organization of myoblast tissues","display_name":"Curvature-guided chiral collective organization of myoblast tissues","publication_year":2026,"publication_date":"2026-08-28","ids":{"openalex":"https://openalex.org/W7204656197","doi":"https://doi.org/10.64898/2026.08.25.747076"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.25.747076","doi":"https://doi.org/10.64898/2026.08.25.747076","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.25.747076","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.64898/2026.08.25.747076","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049042673","display_name":"Yuan Shen","orcid":"https://orcid.org/0000-0003-1332-5843","observed_orcids":["https://orcid.org/0000-0003-1332-5843"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Yuan Shen","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":"https://orcid.org/0000-0003-1332-5843","affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058114936","display_name":"Rushikesh Shinde","orcid":"https://orcid.org/0000-0003-0082-087X","observed_orcids":["https://orcid.org/0000-0003-0082-087X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210127056","display_name":"Laboratoire Mati\u00e8re et Syst\u00e8mes Complexes","ror":"https://ror.org/032w6q449","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210095849","https://openalex.org/I4210127056"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Rushikesh Shinde","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, CNRS, Laboratoire Mati\u00e8re et Syst\u00e8mes Complexes, F-75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Laboratoire Mati\u00e8re et Syst\u00e8mes Complexes, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210127056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102840200","display_name":"Wang Xi","orcid":"https://orcid.org/0000-0002-4231-6295","observed_orcids":["https://orcid.org/0000-0002-4231-6295"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Wang Xi","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000089365","display_name":"Sushil Dubey","orcid":"https://orcid.org/0000-0002-8964-9062","observed_orcids":["https://orcid.org/0000-0002-8964-9062"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210110240","display_name":"Max Planck Institute for the Science of Light","ror":"https://ror.org/020as7681","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210110240"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["DE","FR"],"is_corresponding":false,"raw_author_name":"Sushil Dubey","raw_affiliation_strings":["Department of Physics, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany","Max-Planck-Zentrum for Physics und Medicine and Max Planck Institute for the Science of Light, Erlangen, Germany","Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany","institution_ids":["https://openalex.org/I181369854"]},{"raw_affiliation_string":"Max-Planck-Zentrum for Physics und Medicine and Max Planck Institute for the Science of Light, Erlangen, Germany","institution_ids":["https://openalex.org/I4210110240"]},{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017824612","display_name":"Yoann Le Toquin","orcid":"https://orcid.org/0009-0006-1668-885X","observed_orcids":["https://orcid.org/0009-0006-1668-885X"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I4210110240","display_name":"Max Planck Institute for the Science of Light","ror":"https://ror.org/020as7681","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210110240"]},{"id":"https://openalex.org/I4210125101","display_name":"Institut NeuroMyoG\u00e8ne","ror":"https://ror.org/0322sf130","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210125101"]},{"id":"https://openalex.org/I4405258652","display_name":"M\u00e9canismes en sciences int\u00e9gratives du vivant","ror":"https://ror.org/01138xk88","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4405258652"]}],"countries":["DE","FR"],"is_corresponding":false,"raw_author_name":"Yoann Le Toquin","raw_affiliation_strings":["Department of Physics, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany","Max-Planck-Zentrum for Physics und Medicine and Max Planck Institute for the Science of Light, Erlangen, Germany","MeLis, INMG, Universit\u00e9 Claude Bernard Lyon1, CNRS UMR 5284, INSERM U1314, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany","institution_ids":["https://openalex.org/I181369854"]},{"raw_affiliation_string":"Max-Planck-Zentrum for Physics und Medicine and Max Planck Institute for the Science of Light, Erlangen, Germany","institution_ids":["https://openalex.org/I4210110240"]},{"raw_affiliation_string":"MeLis, INMG, Universit\u00e9 Claude Bernard Lyon1, CNRS UMR 5284, INSERM U1314, Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210125101","https://openalex.org/I4405258652"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148613901","display_name":"Joanna Da Costa Oterelo Martins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210113666","display_name":"Institut de Myologie","ror":"https://ror.org/0270xt841","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210100892","https://openalex.org/I4210113666"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]},{"id":"https://openalex.org/I4389425387","display_name":"Centre de Recherche en Myologie","ror":"https://ror.org/02e3eqz10","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4389425387"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Joanna Da Costa Oterelo Martins","raw_affiliation_strings":["Sorbonne Universit\u00e9, INSERM U974, Institute of Myology, Center of Research in Myology, Paris, France","Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sorbonne Universit\u00e9, INSERM U974, Institute of Myology, Center of Research in Myology, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210113666","https://openalex.org/I4389425387"]},{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115575529","display_name":"Lucas Anger","orcid":"https://orcid.org/0009-0004-9878-1630","observed_orcids":["https://orcid.org/0009-0004-9878-1630"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lucas Anger","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039756829","display_name":"Andreas Schoenit","orcid":"https://orcid.org/0000-0003-3714-5636","observed_orcids":["https://orcid.org/0000-0003-3714-5636"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Andreas Schoenit","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075146422","display_name":"Gianluca Grenci","orcid":"https://orcid.org/0000-0001-9313-6748","observed_orcids":["https://orcid.org/0000-0001-9313-6748"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4405277086","display_name":"Mechanobiology Institute","ror":"https://ror.org/01dh8a666","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4405277086"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Gianluca Grenci","raw_affiliation_strings":["Biomedical Engineering Department, National University of Singapore, Singapore","Mechanobiology Institute, National University of Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-9313-6748","affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Mechanobiology Institute, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4405277086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045468870","display_name":"Christophe Marcelle","orcid":"https://orcid.org/0000-0002-9612-7609","observed_orcids":["https://orcid.org/0000-0002-9612-7609"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210125101","display_name":"Institut NeuroMyoG\u00e8ne","ror":"https://ror.org/0322sf130","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210125101"]},{"id":"https://openalex.org/I4405258652","display_name":"M\u00e9canismes en sciences int\u00e9gratives du vivant","ror":"https://ror.org/01138xk88","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4405258652"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christophe Marcelle","raw_affiliation_strings":["MeLis, INMG, Universit\u00e9 Claude Bernard Lyon1, CNRS UMR 5284, INSERM U1314, Lyon, France"],"raw_orcid":"https://orcid.org/0000-0002-9612-7609","affiliations":[{"raw_affiliation_string":"MeLis, INMG, Universit\u00e9 Claude Bernard Lyon1, CNRS UMR 5284, INSERM U1314, Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210125101","https://openalex.org/I4405258652"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081075576","display_name":"Ren\u00e9\u2010Marc M\u00e8ge","orcid":"https://orcid.org/0000-0001-8128-5543","observed_orcids":["https://orcid.org/0000-0001-8128-5543"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ren\u00e9-Marc M\u00e8ge","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":"https://orcid.org/0000-0001-8128-5543","affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038635374","display_name":"Rapha\u00ebl Voituriez","orcid":"https://orcid.org/0000-0001-8746-5713","observed_orcids":["https://orcid.org/0000-0001-8746-5713"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210094907","display_name":"Laboratoire Jean Perrin","ror":"https://ror.org/01ghvgs84","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210094907","https://openalex.org/I4210098836"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Raphael Voituriez","raw_affiliation_strings":["Laboratoire Jean Perrin, CNRS, Sorbonne Universit\u00e9, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire Jean Perrin, CNRS, Sorbonne Universit\u00e9, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210094907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046840747","display_name":"Andrew Callan-Jones","orcid":"https://orcid.org/0000-0001-8769-687X","observed_orcids":["https://orcid.org/0000-0001-8769-687X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210127056","display_name":"Laboratoire Mati\u00e8re et Syst\u00e8mes Complexes","ror":"https://ror.org/032w6q449","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210095849","https://openalex.org/I4210127056"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Andrew Callan-Jones","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, CNRS, Laboratoire Mati\u00e8re et Syst\u00e8mes Complexes, F-75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Laboratoire Mati\u00e8re et Syst\u00e8mes Complexes, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210127056"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005890720","display_name":"Beno\u00eet Ladoux","orcid":"https://orcid.org/0000-0003-2086-1556","observed_orcids":["https://orcid.org/0000-0003-2086-1556"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210110240","display_name":"Max Planck Institute for the Science of Light","ror":"https://ror.org/020as7681","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210110240"]},{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["DE","FR"],"is_corresponding":false,"raw_author_name":"Benoit Ladoux","raw_affiliation_strings":["Department of Physics, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany","Max-Planck-Zentrum for Physics und Medicine and Max Planck Institute for the Science of Light, Erlangen, Germany","Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France"],"raw_orcid":"https://orcid.org/0000-0003-2086-1556","affiliations":[{"raw_affiliation_string":"Department of Physics, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany","institution_ids":["https://openalex.org/I181369854"]},{"raw_affiliation_string":"Max-Planck-Zentrum for Physics und Medicine and Max Planck Institute for the Science of Light, Erlangen, Germany","institution_ids":["https://openalex.org/I4210110240"]},{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, CNRS, Institut Jacques Monod, F-75013 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5049042673"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210113761"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11737","display_name":"Advanced Materials and Mechanics","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/surface-curvature","display_name":"surface curvature","score":0.9350000023841858},{"id":"https://openalex.org/keywords/myoblasts","display_name":"myoblasts","score":0.7979999780654907},{"id":"https://openalex.org/keywords/myogenesis","display_name":"myogenesis","score":0.8830000162124634},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.9369999766349792},{"id":"https://openalex.org/keywords/curvature-gradient","display_name":"curvature gradient","score":0.6710000038146973},{"id":"https://openalex.org/keywords/continuum-theory","display_name":"continuum theory","score":0.6029999852180481},{"id":"https://openalex.org/keywords/tissue-morphogenesis","display_name":"tissue morphogenesis","score":0.8230000138282776},{"id":"https://openalex.org/keywords/curved-substrates","display_name":"curved substrates","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C195065555","wikidata":"https://www.wikidata.org/wiki/Q214881","display_name":"Curvature","level":2,"score":0.8187999725341797},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5386999845504761},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.47600001096725464},{"id":"https://openalex.org/C112680207","wikidata":"https://www.wikidata.org/wiki/Q714886","display_name":"Regular polygon","level":2,"score":0.4659000039100647},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.4643000066280365},{"id":"https://openalex.org/C74318829","wikidata":"https://www.wikidata.org/wiki/Q36458","display_name":"Multicellular organism","level":3,"score":0.4465000033378601},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.3971000015735626},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.39660000801086426},{"id":"https://openalex.org/C100339178","wikidata":"https://www.wikidata.org/wiki/Q2548752","display_name":"Collective behavior","level":2,"score":0.36169999837875366},{"id":"https://openalex.org/C124668440","wikidata":"https://www.wikidata.org/wiki/Q2305173","display_name":"Chirality (physics)","level":5,"score":0.35830000042915344},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.35359999537467957},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3416999876499176},{"id":"https://openalex.org/C139676723","wikidata":"https://www.wikidata.org/wiki/Q1193832","display_name":"Sign (mathematics)","level":2,"score":0.31779998540878296},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.3165999948978424},{"id":"https://openalex.org/C33026886","wikidata":"https://www.wikidata.org/wiki/Q593950","display_name":"Rotational symmetry","level":2,"score":0.30959999561309814},{"id":"https://openalex.org/C134786449","wikidata":"https://www.wikidata.org/wiki/Q3391255","display_name":"Planar","level":2,"score":0.3057999908924103},{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.2971000075340271},{"id":"https://openalex.org/C74650414","wikidata":"https://www.wikidata.org/wiki/Q11397","display_name":"Classical mechanics","level":1,"score":0.296099990606308},{"id":"https://openalex.org/C140820882","wikidata":"https://www.wikidata.org/wiki/Q732722","display_name":"Vortex","level":2,"score":0.28299999237060547},{"id":"https://openalex.org/C74050887","wikidata":"https://www.wikidata.org/wiki/Q848368","display_name":"Rotation (mathematics)","level":2,"score":0.2816999852657318},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.27810001373291016},{"id":"https://openalex.org/C83330619","wikidata":"https://www.wikidata.org/wiki/Q21124872","display_name":"NODAL","level":2,"score":0.2648000121116638},{"id":"https://openalex.org/C2776799497","wikidata":"https://www.wikidata.org/wiki/Q484298","display_name":"Surface (topology)","level":2,"score":0.26269999146461487},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.26010000705718994},{"id":"https://openalex.org/C2780499737","wikidata":"https://www.wikidata.org/wiki/Q24755076","display_name":"Collective motion","level":2,"score":0.25600001215934753},{"id":"https://openalex.org/C38976095","wikidata":"https://www.wikidata.org/wiki/Q752641","display_name":"Asymmetry","level":2,"score":0.251800000667572},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.25130000710487366}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.64898/2026.08.25.747076","doi":"https://doi.org/10.64898/2026.08.25.747076","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.25.747076","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:HAL:hal-05760508v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05760508","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2026","raw_type":"info:eu-repo/semantics/preprint"}],"best_oa_location":{"id":"doi:10.64898/2026.08.25.747076","doi":"https://doi.org/10.64898/2026.08.25.747076","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.25.747076","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G322142213","display_name":null,"funder_award_id":"LT0007/2023-C","funder_id":"https://openalex.org/F4320320338","funder_display_name":"Human Frontier Science Program"},{"id":"https://openalex.org/G340842263","display_name":"From simple to stratifying epithelia: unifying and diverging adhesive and mechanical principles","funder_award_id":"ANR-22-CE92-0048","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5600881104","display_name":"Genetic and Mechanical Control of Myoblast Fusion.","funder_award_id":"ANR-19-CE13-0016","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320308269","display_name":"Alexander von Humboldt-Stiftung","ror":"https://ror.org/012kf4317"},{"id":"https://openalex.org/F4320320338","display_name":"Human Frontier Science Program","ror":"https://ror.org/02ebx7v45"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1974108972","https://openalex.org/W1989723819","https://openalex.org/W2018430965","https://openalex.org/W2020474196","https://openalex.org/W2022731004","https://openalex.org/W2029914169","https://openalex.org/W2042478670","https://openalex.org/W2052598470","https://openalex.org/W2062427797","https://openalex.org/W2074781111","https://openalex.org/W2075755310","https://openalex.org/W2078275241","https://openalex.org/W2082274155","https://openalex.org/W2089540877","https://openalex.org/W2101450485","https://openalex.org/W2111750063","https://openalex.org/W2131002032","https://openalex.org/W2140775386","https://openalex.org/W2159670921","https://openalex.org/W2170365711","https://openalex.org/W2181440869","https://openalex.org/W2517314340","https://openalex.org/W2520869106","https://openalex.org/W2529052661","https://openalex.org/W2551398040","https://openalex.org/W2606063864","https://openalex.org/W2797166851","https://openalex.org/W2901703616","https://openalex.org/W2901767132","https://openalex.org/W2921241224","https://openalex.org/W2971447314","https://openalex.org/W3111521801","https://openalex.org/W3132596616","https://openalex.org/W3160093108","https://openalex.org/W3161396725","https://openalex.org/W3203725817","https://openalex.org/W3211813782","https://openalex.org/W4293464015","https://openalex.org/W4295706104","https://openalex.org/W4300861260","https://openalex.org/W4310638986","https://openalex.org/W4320033602","https://openalex.org/W4320891003","https://openalex.org/W4323042834","https://openalex.org/W4360826981","https://openalex.org/W4366732305","https://openalex.org/W4388395150","https://openalex.org/W4392010531","https://openalex.org/W4392589850","https://openalex.org/W4404572703","https://openalex.org/W7204006799"],"related_works":["https://openalex.org/W7214553019","https://openalex.org/W4384026228","https://openalex.org/W4393023200","https://openalex.org/W2971784287","https://openalex.org/W4323042834","https://openalex.org/W3132596616","https://openalex.org/W2583989232","https://openalex.org/W3007121632","https://openalex.org/W4281611429","https://openalex.org/W4313557341"],"abstract_inverted_index":{"Abstract":[0],"Surface":[1],"curvature":[2,26,106,124,144,180,190,217,253],"is":[3,58,136,254],"a":[4,29,82,132,242,269],"fundamental":[5],"geometric":[6,30,211],"cue":[7],"in":[8,14,43,87,238],"tissue":[9,274],"morphogenesis,":[10],"yet":[11,175],"its":[12],"role":[13],"guiding":[15,273],"collective":[16,182],"cell":[17,183,201],"organization":[18,184,275],"has":[19],"remained":[20],"elusive.":[21],"Here,":[22],"we":[23],"show":[24,188],"that":[25,33,189],"acts":[27],"as":[28,268],"control":[31,193,212],"parameter":[32,271],"shapes":[34,181],"supracellular":[35],"alignment":[36],"and":[37,60,111,162,185,232,276,284],"chirality":[38,245],"while":[39,130],"modulating":[40],"myogenic":[41,140,260],"differentiation":[42],"myoblast":[44],"tissues.":[45,167],"Cells":[46],"cultured":[47],"on":[48,172],"curved":[49,173],"substrates":[50,118],"self-organize":[51],"into":[52],"robust":[53],"helical":[54,93,200],"assemblies":[55,202],"whose":[56],"handedness":[57,198],"set,":[59],"can":[61,191],"be":[62],"reversed,":[63],"by":[64],"the":[65,78,92,109,159,197],"sign":[66],"of":[67,113,165,199],"curvature:":[68],"convex":[69,207],"fibers":[70],"produce":[71],"right-handed":[72],"helices,":[73],"whereas":[74],"concave":[75],"channels":[76],"invert":[77],"chirality.":[79],"We":[80,187],"identify":[81,265],"previously":[83],"hidden":[84],"clockwise":[85,236],"bias":[86,237],"single-cell":[88,239],"motion":[89],"associated":[90,138,255],"with":[91,119,139,142,256,280],"actin":[94],"cytoskeleton.":[95],"A":[96],"minimal":[97],"continuum":[98],"theory":[99],"coupling":[100,228],"an":[101,233],"effective":[102],"chiral":[103,115],"drive":[104],"to":[105,146,208,214],"quantitatively":[107],"captures":[108],"emergence":[110],"reversal":[112],"tissue-scale":[114],"alignment.":[116],"On":[117],"spatially":[120],"varying":[121],"curvature,":[122],"local":[123,230],"gradients":[125],"organize":[126],"patterned":[127],"multicellular":[128,194,222],"architectures":[129],"preserving":[131],"global":[133],"handedness.":[134],"Curvature":[135],"also":[137],"state,":[141,279],"higher":[143,252],"linked":[145],"reduced":[147,257],"or":[148,258],"delayed":[149,259],"differentiation.":[150,261],"Together,":[151,262],"these":[152,263],"findings":[153],"reveal":[154],"how":[155,179],"complex":[156,216],"geometries":[157],"shape":[158],"alignment,":[160],"symmetry,":[161],"cellular":[163,278],"state":[164],"living":[166],"Significance":[168],"statement":[169],"Tissues":[170],"develop":[171],"surfaces,":[174],"it":[176],"remains":[177],"unclear":[178],"function.":[186],"reliably":[192],"chirality,":[195],"reversing":[196],"when":[203],"surfaces":[204],"switch":[205],"from":[206,227],"concave.":[209],"This":[210],"extends":[213],"more":[215],"landscapes,":[218],"which":[219],"pattern":[220],"distinct":[221],"architectures.":[223],"Curvature-driven":[224],"order":[225],"arises":[226],"between":[229],"geometry":[231,267],"intrinsic,":[234],"actin-dependent":[235],"motion,":[240],"revealing":[241],"route":[243],"for":[244,272,282],"transfer":[246],"across":[247],"scales.":[248],"Beyond":[249],"organizing":[250],"tissues,":[251],"results":[264],"surface":[266],"design":[270],"influencing":[277],"implications":[281],"morphogenesis":[283],"biomaterial":[285],"design.":[286]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-08-30T00:00:00"}