{"id":"https://openalex.org/W7204653425","doi":"https://doi.org/10.64898/2026.08.27.747499","title":"SALRR: Scalable Analysis of Long-Read RNA-Seq Enables Comprehensive Transcriptome Profiling in Human Brain","display_name":"SALRR: Scalable Analysis of Long-Read RNA-Seq Enables Comprehensive Transcriptome Profiling in Human Brain","publication_year":2026,"publication_date":"2026-08-29","ids":{"openalex":"https://openalex.org/W7204653425","doi":"https://doi.org/10.64898/2026.08.27.747499"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.27.747499","doi":"https://doi.org/10.64898/2026.08.27.747499","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.27.747499","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/29/2026.08.27.747499.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/29/2026.08.27.747499.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019518891","display_name":"Cedric Kouam","orcid":"https://orcid.org/0000-0003-4949-9052","observed_orcids":["https://orcid.org/0000-0003-4949-9052"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cedric Kouam","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133544863","display_name":"Jackson Mingle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jackson Mingle","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027391800","display_name":"Pilar \u00c1lvarez Jerez","orcid":"https://orcid.org/0000-0002-5812-1898","observed_orcids":["https://orcid.org/0000-0002-5812-1898"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]},{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Pilar \u00c1lvarez Jerez","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK","Global Parkinson\u2019s Genetic Program (GP2), Chevy Chase, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Global Parkinson\u2019s Genetic Program (GP2), Chevy Chase, MD, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139363569","display_name":"Allison Evans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allison Evans","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138910010","display_name":"Abraham Moller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210086327","display_name":"Data Tecnica International (United States)","ror":"https://ror.org/001h41c24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210086327"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abraham Moller","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","DataTecnica, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"DataTecnica, Washington, DC, USA","institution_ids":["https://openalex.org/I4210086327"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067667773","display_name":"Breeana Baker","orcid":"https://orcid.org/0009-0006-0193-6558","observed_orcids":["https://orcid.org/0009-0006-0193-6558"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Breeana Baker","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077123205","display_name":"Cory A. Weller","orcid":"https://orcid.org/0000-0001-6965-5599","observed_orcids":["https://orcid.org/0000-0001-6965-5599"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210086327","display_name":"Data Tecnica International (United States)","ror":"https://ror.org/001h41c24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210086327"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cory Weller","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","DataTecnica, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"DataTecnica, Washington, DC, USA","institution_ids":["https://openalex.org/I4210086327"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026216048","display_name":"Kimberly Paquette","orcid":"https://orcid.org/0000-0003-3989-4614","observed_orcids":["https://orcid.org/0000-0003-3989-4614"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Paquette","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060654709","display_name":"Janet Brooks","orcid":"https://orcid.org/0009-0004-4762-132X","observed_orcids":["https://orcid.org/0009-0004-4762-132X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janet Brooks","raw_affiliation_strings":["Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042465149","display_name":"Spencer M. Grant","orcid":"https://orcid.org/0000-0002-7278-0347","observed_orcids":["https://orcid.org/0000-0002-7278-0347"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Spencer M Grant","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118784462","display_name":"Alexis Ayuketah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexis Ayuketah","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013925822","display_name":"Melissa Meredith","orcid":"https://orcid.org/0000-0001-5736-3193","observed_orcids":["https://orcid.org/0000-0001-5736-3193"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210086327","display_name":"Data Tecnica International (United States)","ror":"https://ror.org/001h41c24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210086327"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa Meredith","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","DataTecnica, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"DataTecnica, Washington, DC, USA","institution_ids":["https://openalex.org/I4210086327"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148610941","display_name":"Joanna Palade","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanna Palade","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053048712","display_name":"Laksh Malik","orcid":"https://orcid.org/0000-0002-2498-146X","observed_orcids":["https://orcid.org/0000-0002-2498-146X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laksh Malik","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148588659","display_name":"Kristen Hise","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristen Hise","raw_affiliation_strings":["Hamilton Company, Reno, NV, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hamilton Company, Reno, NV, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051161812","display_name":"Jessica Anderson","orcid":"https://orcid.org/0009-0006-2016-7109","observed_orcids":["https://orcid.org/0009-0006-2016-7109"]},"institutions":[{"id":"https://openalex.org/I4210155982","display_name":"Oxford Nanopore Technologies (United Kingdom)","ror":"https://ror.org/04hyfx005","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210155982"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jessica Anderson","raw_affiliation_strings":["Oxford Nanopore Technologies, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Nanopore Technologies, Oxford, UK","institution_ids":["https://openalex.org/I4210155982"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071754523","display_name":"Rob Harbert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155982","display_name":"Oxford Nanopore Technologies (United Kingdom)","ror":"https://ror.org/04hyfx005","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210155982"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Harbert","raw_affiliation_strings":["Oxford Nanopore Technologies, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Nanopore Technologies, Oxford, UK","institution_ids":["https://openalex.org/I4210155982"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001453107","display_name":"Yilei Fu","orcid":"https://orcid.org/0000-0002-7721-7027","observed_orcids":["https://orcid.org/0000-0002-7721-7027"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yilei Fu","raw_affiliation_strings":["Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076142459","display_name":"Xinchang Zheng","orcid":"https://orcid.org/0000-0001-5739-861X","observed_orcids":["https://orcid.org/0000-0001-5739-861X"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinchang Zheng","raw_affiliation_strings":["Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA"],"raw_orcid":"https://orcid.org/0000-0001-5739-861X","affiliations":[{"raw_affiliation_string":"Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033311649","display_name":"Sonia Garc\u00eda-Ruiz","orcid":"https://orcid.org/0000-0003-4913-5312","observed_orcids":["https://orcid.org/0000-0003-4913-5312"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sonia Garc\u00eda-Ruiz","raw_affiliation_strings":["Dementia Research Institute, University of Cambridge, Cambridge, UK","Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK","Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072234452","display_name":"Emil Karl Gustavsson","orcid":"https://orcid.org/0000-0003-0541-7537","observed_orcids":["https://orcid.org/0000-0003-0541-7537"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emil K Gustavsson","raw_affiliation_strings":["Dementia Research Institute, University of Cambridge, Cambridge, UK","Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK","Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072627174","display_name":"Cornelis Blauwendraat","orcid":"https://orcid.org/0000-0001-9358-8111","observed_orcids":["https://orcid.org/0000-0001-9358-8111"]},"institutions":[{"id":"https://openalex.org/I4405263423","display_name":"Coalition for Aligning Science","ror":"https://ror.org/00rf4ez40","country_code":"US","type":"company","lineage":["https://openalex.org/I4405263423"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cornelis Blauwendraat","raw_affiliation_strings":["Coalition for Aligning Science, Chevy Chase, MD, USA","Global Parkinson\u2019s Genetic Program (GP2), Chevy Chase, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Coalition for Aligning Science, Chevy Chase, MD, USA","institution_ids":["https://openalex.org/I4405263423"]},{"raw_affiliation_string":"Global Parkinson\u2019s Genetic Program (GP2), Chevy Chase, MD, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042439287","display_name":"Mina Ryten","orcid":"https://orcid.org/0000-0001-9520-6957","observed_orcids":["https://orcid.org/0000-0001-9520-6957"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4389425352","display_name":"NIHR Cambridge Biomedical Research Centre","ror":"https://ror.org/05m8dr349","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I2802466933","https://openalex.org/I34931013","https://openalex.org/I4389425352"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mina Ryten","raw_affiliation_strings":["Dementia Research Institute, University of Cambridge, Cambridge, UK","Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK","Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK","Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4389425352"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037440162","display_name":"Fritz Joachim Sedlazeck","orcid":"https://orcid.org/0000-0001-6040-2691","observed_orcids":["https://orcid.org/0000-0001-6040-2691"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fritz J Sedlazeck","raw_affiliation_strings":["Department of Computer Science, Rice University, Houston, TX, USA","Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA","Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Rice University, Houston, TX, USA","institution_ids":["https://openalex.org/I74775410"]},{"raw_affiliation_string":"Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048196698","display_name":"Luigi Ferrucci","orcid":"https://orcid.org/0000-0002-6273-1613","observed_orcids":["https://orcid.org/0000-0002-6273-1613"]},"institutions":[{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luigi Ferrucci","raw_affiliation_strings":["Longitudinal Studies Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Longitudinal Studies Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Baltimore, MD, USA","institution_ids":["https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005340246","display_name":"Jesse Raphael Gibbs","orcid":"https://orcid.org/0000-0002-6985-0658","observed_orcids":["https://orcid.org/0000-0002-6985-0658"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Raphael Gibbs","raw_affiliation_strings":["Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-6985-0658","affiliations":[{"raw_affiliation_string":"Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063736296","display_name":"Jinhui Ding","orcid":"https://orcid.org/0000-0002-4691-4524","observed_orcids":["https://orcid.org/0000-0002-4691-4524"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jinhui Ding","raw_affiliation_strings":["Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055082420","display_name":"Xylena Reed","orcid":"https://orcid.org/0000-0002-7563-9365","observed_orcids":["https://orcid.org/0000-0002-7563-9365"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xylena Reed","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113839983","display_name":"Mike A. Nalls","orcid":"https://orcid.org/0000-0003-0319-4325","observed_orcids":["https://orcid.org/0000-0003-0319-4325"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210086327","display_name":"Data Tecnica International (United States)","ror":"https://ror.org/001h41c24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210086327"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mike Nalls","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","DataTecnica, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"DataTecnica, Washington, DC, USA","institution_ids":["https://openalex.org/I4210086327"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064191051","display_name":"Mark Cookson","orcid":"https://orcid.org/0000-0002-1058-3831","observed_orcids":["https://orcid.org/0000-0002-1058-3831"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark R Cookson","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-1058-3831","affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031336237","display_name":"Kendall R. Van Keuren\u2010Jensen","orcid":"https://orcid.org/0000-0001-8833-6323","observed_orcids":["https://orcid.org/0000-0001-8833-6323"]},"institutions":[{"id":"https://openalex.org/I1284308235","display_name":"Translational Genomics Research Institute","ror":"https://ror.org/02hfpnk21","country_code":"US","type":"facility","lineage":["https://openalex.org/I1284308235"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kendall Van Keuren-Jensen","raw_affiliation_strings":["Bioinnovation and Genome Sciences Division, Translational Genomics Research Institute, Phoenix, AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinnovation and Genome Sciences Division, Translational Genomics Research Institute, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I1284308235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139308572","display_name":"Elizabeth Hutchins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1284308235","display_name":"Translational Genomics Research Institute","ror":"https://ror.org/02hfpnk21","country_code":"US","type":"facility","lineage":["https://openalex.org/I1284308235"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210086327","display_name":"Data Tecnica International (United States)","ror":"https://ror.org/001h41c24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210086327"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth Hutchins","raw_affiliation_strings":["Bioinnovation and Genome Sciences Division, Translational Genomics Research Institute, Phoenix, AZ, USA","Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","DataTecnica, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinnovation and Genome Sciences Division, Translational Genomics Research Institute, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I1284308235"]},{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"DataTecnica, Washington, DC, USA","institution_ids":["https://openalex.org/I4210086327"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018121239","display_name":"Miten Jain","orcid":"https://orcid.org/0000-0002-4571-3982","observed_orcids":["https://orcid.org/0000-0002-4571-3982"]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Miten Jain","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","Department of Bioengineering, Department of Physics, Khoury College of Computer Sciences, Northeastern University, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-4571-3982","affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]},{"raw_affiliation_string":"Department of Bioengineering, Department of Physics, Khoury College of Computer Sciences, Northeastern University, Boston, MA, USA","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004869403","display_name":"Kimberley J. Billingsley","orcid":"https://orcid.org/0000-0002-8003-4029","observed_orcids":["https://orcid.org/0000-0002-8003-4029"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberley J Billingsley","raw_affiliation_strings":["Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-8003-4029","affiliations":[{"raw_affiliation_string":"Center for Alzheimer\u2019s and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5018121239"],"corresponding_institution_ids":["https://openalex.org/I12912129","https://openalex.org/I1299303238","https://openalex.org/I4210110767","https://openalex.org/I4210136897"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.5952000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.5952000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.27559998631477356,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.11410000175237656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-read-rna-sequencing","display_name":"long-read RNA sequencing","score":0.777999997138977},{"id":"https://openalex.org/keywords/human-brain-transcriptome","display_name":"human brain transcriptome","score":0.8730000257492065},{"id":"https://openalex.org/keywords/oxford-nanopore-sequencing","display_name":"Oxford Nanopore sequencing","score":0.8299999833106995},{"id":"https://openalex.org/keywords/snakemake-workflow","display_name":"Snakemake workflow","score":0.7329999804496765},{"id":"https://openalex.org/keywords/novel-splice-variants","display_name":"novel splice variants","score":0.9390000104904175},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.9359999895095825},{"id":"https://openalex.org/keywords/gba1","display_name":"GBA1","score":0.6460000276565552},{"id":"https://openalex.org/keywords/cyclin-f","display_name":"cyclin F","score":0.8330000042915344},{"id":"https://openalex.org/keywords/chchd10","display_name":"CHCHD10","score":0.9990000128746033},{"id":"https://openalex.org/keywords/trem2","display_name":"TREM2","score":0.9779999852180481},{"id":"https://openalex.org/keywords/rna-degradation","display_name":"RNA degradation","score":0.39100000262260437}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6467999815940857},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6445000171661377},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.6121000051498413},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.5435000061988831},{"id":"https://openalex.org/C2780989783","wikidata":"https://www.wikidata.org/wiki/Q7578557","display_name":"splice","level":3,"score":0.4959999918937683},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.490200012922287},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4745999872684479},{"id":"https://openalex.org/C189482833","wikidata":"https://www.wikidata.org/wiki/Q869146","display_name":"cDNA library","level":4,"score":0.4530999958515167},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.4323999881744385},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43149998784065247},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.41290000081062317},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.4027999937534332},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.38019999861717224},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.358599990606308},{"id":"https://openalex.org/C107397762","wikidata":"https://www.wikidata.org/wiki/Q2542347","display_name":"RNA-Seq","level":5,"score":0.35440000891685486},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.3513999879360199},{"id":"https://openalex.org/C132917006","wikidata":"https://www.wikidata.org/wiki/Q5250436","display_name":"Deep sequencing","level":4,"score":0.3425000011920929},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.32820001244544983},{"id":"https://openalex.org/C66746571","wikidata":"https://www.wikidata.org/wiki/Q1134833","display_name":"ENCODE","level":3,"score":0.31279999017715454},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.29989999532699585},{"id":"https://openalex.org/C57273362","wikidata":"https://www.wikidata.org/wiki/Q576722","display_name":"Decoding methods","level":2,"score":0.29910001158714294},{"id":"https://openalex.org/C2988867146","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Human disease","level":3,"score":0.2924000024795532},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.2863999903202057},{"id":"https://openalex.org/C16671776","wikidata":"https://www.wikidata.org/wiki/Q5420592","display_name":"Exome sequencing","level":4,"score":0.2768000066280365},{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.2502000033855438}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.08.27.747499","doi":"https://doi.org/10.64898/2026.08.27.747499","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.27.747499","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/29/2026.08.27.747499.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.08.27.747499","doi":"https://doi.org/10.64898/2026.08.27.747499","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.27.747499","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/08/29/2026.08.27.747499.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1265246815","display_name":null,"funder_award_id":"ZIAAG000538","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G1656305939","display_name":null,"funder_award_id":"OT2OD027852","funder_id":"https://openalex.org/F4320310598","funder_display_name":"Amazon Web Services"},{"id":"https://openalex.org/G2258677762","display_name":null,"funder_award_id":"OT2OD032100","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G6141462147","display_name":null,"funder_award_id":"ZIAAG000534","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G9000871901","display_name":"Center for Alzheimer's and Related Dementias (CARD): Long-read DNA sequencing of Alzheimers Disease and Related Dementias cases","funder_award_id":"ZIAAG000538","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000890187","display_name":"Single-molecule sequence assembly and analysis","funder_award_id":"ZIAHG200398","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G9000918417","display_name":"Center for Alzheimer's and Related Dementias (CARD):  Harmonized Data-Derived Resources for the Alzheimer's Disease and Related Dementias Community","funder_award_id":"ZIAAG000534","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320310598","display_name":"Amazon Web Services","ror":"https://ror.org/04mv4n011"},{"id":"https://openalex.org/F4320312414","display_name":"Oxford Nanopore Technologies","ror":"https://ror.org/04hyfx005"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204653425.pdf","grobid_xml":"https://content.openalex.org/works/W7204653425.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W4385650331","https://openalex.org/W4399032447","https://openalex.org/W4405673833","https://openalex.org/W4408951499","https://openalex.org/W7165879413"],"related_works":["https://openalex.org/W4312086233","https://openalex.org/W7128880010","https://openalex.org/W7128786745","https://openalex.org/W4317553434","https://openalex.org/W6939966311","https://openalex.org/W4403450377","https://openalex.org/W4408206834","https://openalex.org/W3086120018","https://openalex.org/W7204019026","https://openalex.org/W4416937569"],"abstract_inverted_index":{"ABSTRACT":[0],"Isoform-resolved":[1],"transcriptomics":[2,187],"is":[3],"fundamental":[4],"to":[5,23,28,58,106,121],"decoding":[6],"the":[7,11,35,69,128],"molecular":[8],"complexity":[9],"of":[10,37,48],"human":[12],"brain,":[13],"yet":[14],"population-scale":[15],"long-read":[16,64],"RNA":[17,29,92],"sequencing":[18,159],"has":[19],"remained":[20],"inaccessible":[21],"due":[22],"labor-intensive":[24],"library":[25,66],"preparation,":[26],"sensitivity":[27],"degradation":[30],"in":[31,188],"postmortem":[32,123],"tissue,":[33],"and":[34,54,80,116,151,170,175,191],"absence":[36],"integrated,":[38],"reproducible":[39],"analysis":[40],"pipelines.":[41],"Here":[42],"we":[43],"present":[44],"SALRR":[45,134],"(Scalable":[46],"Analysis":[47],"Long-Read":[49],"RNA-seq),":[50],"an":[51],"integrated":[52],"wet-lab":[53],"computational":[55],"platform":[56,74],"designed":[57],"overcome":[59],"these":[60],"barriers.":[61],"Automated":[62],"ONT":[63,103],"cDNA":[65],"preparation":[67],"on":[68],"Hamilton":[70],"Microlab":[71],"NGS":[72],"STAR":[73],"reduces":[75],"hands-on":[76],"time":[77],"by":[78,157],"67%":[79],"enables":[81],"24":[82],"libraries":[83],"per":[84,86],"operator":[85],"day":[87],"while":[88],"maintaining":[89],"performance":[90],"across":[91],"integrity":[93],"values.":[94],"A":[95],"modular,":[96],"Snakemake-based":[97],"pipeline":[98],"performs":[99],"end-to-end":[100],"processing":[101],"from":[102,127,139,148],"signal":[104],"data":[105],"isoform-level":[107],"quantification,":[108],"incorporating":[109],"SIRV":[110],"spike-in":[111],"calibration,":[112],"multi-stage":[113],"quality":[114],"control,":[115],"stringent":[117],"isoform":[118],"validation.":[119],"Applied":[120],"10":[122],"frontal":[124],"cortex":[125],"samples":[126],"North":[129],"American":[130],"Brain":[131],"Expression":[132],"Consortium,":[133],"identified":[135],"31,607":[136],"high-confidence":[137],"isoforms":[138],"10,075":[140],"genes,":[141],"including":[142,163],"8,532":[143],"novel":[144],"splice":[145],"variants":[146],"absent":[147],"GENCODE":[149],"v49,":[150],"complex":[152,192],"splicing":[153],"events":[154],"systematically":[155],"missed":[156],"short-read":[158],"at":[160],"neurodegeneration-relevant":[161],"loci,":[162],"GBA1":[164],",":[165,167,169],"CCNF":[166],"CHCHD10":[168],"TREM2":[171],".":[172],"All":[173],"protocols":[174],"code":[176],"are":[177],"openly":[178],"available,":[179],"providing":[180],"a":[181],"scalable,":[182],"community-ready":[183],"framework":[184],"for":[185],"isoform-resolved":[186],"neurodegeneration,":[189],"aging,":[190],"brain":[193],"disease.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-08-30T00:00:00"}
