{"id":"https://openalex.org/W7204587751","doi":"https://doi.org/10.17605/osf.io/8nhrg","title":"Result-blind framework development and prospective evaluation of treatment-strategy identifiability after response/control in atopic dermatitis (operative prospective registration)","display_name":"Result-blind framework development and prospective evaluation of treatment-strategy identifiability after response/control in atopic dermatitis (operative prospective registration)","publication_year":2026,"publication_date":"2026-08-25","ids":{"openalex":"https://openalex.org/W7204587751","doi":"https://doi.org/10.17605/osf.io/8nhrg"},"language":"en","primary_location":{"id":"pmh:doi:10.17605/osf.io/8nhrg","doi":null,"is_oa":true,"landing_page_url":"https://osf.io/8nhrg","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"StudyRegistration"},"parent_works":[],"lineage":["https://openalex.org/W7204587751"],"child_works_count":0,"type":"preprint","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://osf.io/8nhrg","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5140531103","display_name":"Haoyang Mu","orcid":"https://orcid.org/0009-0006-1909-2429","observed_orcids":["https://orcid.org/0009-0006-1909-2429"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Haoyang Mu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-1909-2429","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5140531103"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.5615000128746033,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.5615000128746033,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.12939999997615814,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.09449999779462814,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/treatment-withdrawal","display_name":"treatment withdrawal","score":0.6970000267028809},{"id":"https://openalex.org/keywords/treatment-tapering","display_name":"treatment tapering","score":0.4650000035762787},{"id":"https://openalex.org/keywords/treatment-switching","display_name":"treatment switching","score":0.45899999141693115},{"id":"https://openalex.org/keywords/treatment-discontinuation","display_name":"treatment discontinuation","score":0.515999972820282},{"id":"https://openalex.org/keywords/reviewer-agreement","display_name":"reviewer agreement","score":0.5260000228881836},{"id":"https://openalex.org/keywords/methodological-evaluation","display_name":"methodological evaluation","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7264999747276306},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6139000058174133},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.572700023651123},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4952000081539154},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.49399998784065247},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.44940000772476196},{"id":"https://openalex.org/C2778329239","wikidata":"https://www.wikidata.org/wiki/Q268667","display_name":"Atopic dermatitis","level":2,"score":0.4011000096797943},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.36970001459121704},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.3675999939441681},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.36160001158714294},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.28700000047683716},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.28459998965263367},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.28279998898506165},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.26919999718666077},{"id":"https://openalex.org/C2776436953","wikidata":"https://www.wikidata.org/wiki/Q5163215","display_name":"Consistency (knowledge bases)","level":2,"score":0.26750001311302185},{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.2653000056743622},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.2565000057220459},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.2531999945640564},{"id":"https://openalex.org/C133462117","wikidata":"https://www.wikidata.org/wiki/Q4929239","display_name":"Data collection","level":2,"score":0.25189998745918274}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:doi:10.17605/osf.io/8nhrg","doi":null,"is_oa":true,"landing_page_url":"https://osf.io/8nhrg","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"StudyRegistration"},{"id":"doi:10.17605/osf.io/8nhrg","doi":"https://doi.org/10.17605/osf.io/8nhrg","is_oa":true,"landing_page_url":"https://doi.org/10.17605/osf.io/8nhrg","pdf_url":null,"source":{"id":"https://openalex.org/S7407050956","display_name":"Open Science Framework","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2799848540","host_organization_name":"Center for Open Science","host_organization_lineage":["https://openalex.org/I2799848540"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"StudyRegistration"}],"best_oa_location":{"id":"pmh:doi:10.17605/osf.io/8nhrg","doi":null,"is_oa":true,"landing_page_url":"https://osf.io/8nhrg","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"StudyRegistration"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4410753760","https://openalex.org/W2060277811","https://openalex.org/W2796983189","https://openalex.org/W2954732678","https://openalex.org/W7164132507","https://openalex.org/W4411732746","https://openalex.org/W7134351439","https://openalex.org/W2417722524","https://openalex.org/W1933543548","https://openalex.org/W4384484813"],"abstract_inverted_index":{"This":[0],"is":[1,37,76,156,177,195,231,237],"the":[2,40,49,77,184,190,247],"operative":[3,181],"prospective":[4,206,240,260],"registration":[5,176,182],"for":[6,259],"a":[7,29,81,107,179],"result-blind":[8,257],"methodological":[9,85],"evaluation":[10],"of":[11,39],"whether":[12,18],"independent":[13],"reviewers":[14],"can":[15],"reproducibly":[16],"determine":[17],"newly":[19],"retrieved":[20],"human":[21],"atopic":[22],"dermatitis/eczema":[23],"study":[24],"records":[25],"identify":[26],"MAINT_VS_WITHDRAW":[27],"after":[28],"prespecified":[30],"response/control":[31],"state.":[32],"The":[33,72,174,221,242,262],"target":[34],"strategy":[35,112],"comparison":[36],"continuation":[38],"same":[41,50],"effective":[42],"treatment":[43],"versus":[44],"direct":[45,70],"complete":[46],"withdrawal":[47],"at":[48,153],"post-response/control":[51],"time":[52],"zero.":[53],"Tapering,":[54],"dose":[55],"reduction,":[56],"interval":[57],"extension,":[58],"switching,":[59],"delayed":[60],"initiation,":[61],"and":[62,90,117,155,228,236,256,271],"uncontrolled":[63],"discontinuation":[64],"are":[65,87,266],"not":[66,196],"silently":[67],"treated":[68],"as":[69,233],"withdrawal.":[71],"primary":[73],"analysis":[74,215],"unit":[75],"arm/strategy":[78],"path":[79],"within":[80],"linked":[82],"study/cohort.":[83],"Primary":[84],"outcomes":[86,95],"rule":[88],"determinability/classifiability":[89],"pre-adjudication":[91],"reviewer":[92,252],"agreement;":[93],"secondary":[94],"include":[96],"adjudication,":[97,212],"lineage":[98,210],"resolution,":[99,211],"unresolved":[100],"classification,":[101],"erroneous":[102],"target-layer":[103],"inclusion":[104],"prevention":[105],"using":[106],"locked":[108],"design-only":[109],"challenge":[110],"set,":[111],"diversity,":[113],"missing":[114],"design":[115],"domains,":[116],"protocol":[118,254],"deviations/amendments.":[119],"No":[120,204],"clinical":[121],"outcomes,":[122],"effect":[123],"estimates,":[124],"real":[125],"instrumental":[126],"variables,":[127],"harmonization,":[128],"linkage":[129],"disequilibrium,":[130],"Mendelian":[131],"randomization,":[132],"pooling,":[133],"or":[134,199,213],"meta-analysis":[135],"will":[136],"be":[137],"performed":[138],"in":[139,189],"this":[140,219],"registration.":[141,220],"An":[142],"earlier":[143],"OSF":[144,165],"registration,":[145],"h3wsu,":[146],"was":[147,168,216,225],"registered":[148],"on":[149],"August":[150,160],"16,":[151],"2026":[152],"00:19:04":[154],"under":[157],"embargo.":[158],"On":[159],"24,":[161],"2026,":[162],"its":[163],"signed-in":[164],"Files":[166],"inventory":[167],"verified":[169],"to":[170,202],"contain":[171],"no":[172],"files.":[173],"present":[175],"therefore":[178],"new":[180],"with":[183],"reviewed":[185],"method":[186,244,264],"attachments":[187,265],"listed":[188],"local":[191],"candidate":[192],"manifest;":[193],"it":[194,230],"an":[197],"amendment":[198],"retroactive":[200],"attachment":[201],"h3wsu.":[203],"formal":[205],"retrieval,":[207],"screening,":[208],"coding,":[209,253],"outcome-bearing":[214],"conducted":[217],"before":[218],"historical":[222],"development":[223,234],"stage":[224],"unregistered,":[226],"retrospective,":[227],"result-blind;":[229],"disclosed":[232],"context":[235],"excluded":[238],"from":[239],"denominators.":[241],"attached":[243],"package":[245],"fixes":[246],"population":[248],"scope,":[249],"source/platform":[250],"matrix,":[251],"freeze,":[255],"boundaries":[258],"execution.":[261],"five":[263],"protocol_v1.1.md,":[267],"analysis_plan_v1.1.md,":[268],"source_platform_matrix_v1.1.csv,":[269],"exact_search_strategies_v1.1.md,":[270],"eligibility_adjudication_codebook_v1.1.md.":[272]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2026-08-29T00:00:00"}