{"id":"https://openalex.org/W7204530309","doi":"https://doi.org/10.1016/j.molstruc.2026.147477","title":"Indole-bearing azoles as highly promising antifungals with in vitro efficacy against clinical isolates of Candida","display_name":"Indole-bearing azoles as highly promising antifungals with in vitro efficacy against clinical isolates of Candida","publication_year":2026,"publication_date":"2026-08-28","ids":{"openalex":"https://openalex.org/W7204530309","doi":"https://doi.org/10.1016/j.molstruc.2026.147477"},"language":"en","primary_location":{"id":"doi:10.1016/j.molstruc.2026.147477","doi":"https://doi.org/10.1016/j.molstruc.2026.147477","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molstruc.2026.147477","pdf_url":null,"source":{"id":"https://openalex.org/S203479135","display_name":"Journal of Molecular Structure","issn_l":"0022-2860","issn":["0022-2860","1872-8014"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Structure","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114689924","display_name":"Yusuf Ataker","orcid":"https://orcid.org/0000-0002-3775-3271","observed_orcids":["https://orcid.org/0000-0002-3775-3271"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Yusuf Ataker","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0000-0002-3775-3271","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006604724","display_name":"Dolunay G\u00fclmez","orcid":"https://orcid.org/0000-0001-9021-0439","observed_orcids":["https://orcid.org/0000-0001-9021-0439"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Dolunay G\u00fclmez","raw_affiliation_strings":["Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-9021-0439","affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143639849","display_name":"Berivan  Ezgi Kaya","orcid":"https://orcid.org/0009-0008-2915-6208","observed_orcids":["https://orcid.org/0009-0008-2915-6208"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Berivan Ezgi Kaya","raw_affiliation_strings":["Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0009-0008-2915-6208","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143640505","display_name":"Erdem Be\u015flio\u011flu","orcid":"https://orcid.org/0009-0005-3665-0712","observed_orcids":["https://orcid.org/0009-0005-3665-0712"]},"institutions":[{"id":"https://openalex.org/I4210139404","display_name":"Lokman Hekim \u00dcniversitesi","ror":"https://ror.org/04v8ap992","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210139404"]},{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Erdem Be\u015flio\u011flu","raw_affiliation_strings":["Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey","Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Lokman Hekim University, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0009-0005-3665-0712","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]},{"raw_affiliation_string":"Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Lokman Hekim University, Ankara, Turkey","institution_ids":["https://openalex.org/I4210139404"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040511667","display_name":"Suna Sabuncuo\u011flu","orcid":"https://orcid.org/0000-0002-9702-4214","observed_orcids":["https://orcid.org/0000-0002-9702-4214"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Suna Sabuncuo\u011flu","raw_affiliation_strings":["Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010502613","display_name":"J\u00e1n Monc\u00f3\u013e","orcid":"https://orcid.org/0000-0003-2153-9753","observed_orcids":["https://orcid.org/0000-0003-2153-9753"]},"institutions":[{"id":"https://openalex.org/I110757952","display_name":"Slovak University of Technology in Bratislava","ror":"https://ror.org/0561ghm58","country_code":"SK","type":"education","lineage":["https://openalex.org/I110757952"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Jan Moncol","raw_affiliation_strings":["Department of Inorganic Chemistry, Institute of Inorganic Chemistry, Technology and Materials, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia"],"raw_orcid":"https://orcid.org/0000-0003-2153-9753","affiliations":[{"raw_affiliation_string":"Department of Inorganic Chemistry, Institute of Inorganic Chemistry, Technology and Materials, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia","institution_ids":["https://openalex.org/I110757952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048361101","display_name":"Sevtap Ar\u0131kan-Akda\u011fl\u0131","orcid":"https://orcid.org/0000-0001-9807-6764","observed_orcids":["https://orcid.org/0000-0001-9807-6764"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Sevtap Arikan-Akdagli","raw_affiliation_strings":["Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139391781","display_name":"Merve Gul","orcid":"https://orcid.org/0009-0006-1107-5675","observed_orcids":["https://orcid.org/0009-0006-1107-5675"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Merve G\u00fcl","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, Faculty of Pharmacy, In\u00f6n\u00fc University, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, In\u00f6n\u00fc University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010616600","display_name":"Mehmet Abdullah Alag\u00f6z","orcid":"https://orcid.org/0000-0001-5190-7196","observed_orcids":["https://orcid.org/0000-0001-5190-7196","https://orcid.org/0000-0001-9961-4616"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"M. Abdullah Alag\u00f6z","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, Faculty of Pharmacy, In\u00f6n\u00fc University, Malatya, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-5190-7196","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, In\u00f6n\u00fc University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078517690","display_name":"Suat Sar\u0131","orcid":"https://orcid.org/0000-0002-8248-4218","observed_orcids":["https://orcid.org/0000-0002-8248-4218"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Suat Sari","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0000-0002-8248-4218","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5078517690"],"corresponding_institution_ids":["https://openalex.org/I66514158"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.65502205,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1381","issue":null,"first_page":"147477","last_page":"147477"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11900","display_name":"Fungal Plant Pathogen Control","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antifungal-agents","display_name":"antifungal agents","score":0.9610000252723694},{"id":"https://openalex.org/keywords/candida","display_name":"Candida","score":0.9169999957084656},{"id":"https://openalex.org/keywords/invasive-candidiasis","display_name":"invasive candidiasis","score":0.8569999933242798},{"id":"https://openalex.org/keywords/azole-resistance","display_name":"azole resistance","score":0.8240000009536743},{"id":"https://openalex.org/keywords/fluconazole-resistance","display_name":"fluconazole resistance","score":0.8709999918937683},{"id":"https://openalex.org/keywords/candida-glabrata","display_name":"Candida glabrata","score":0.8510000109672546},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.8460000157356262},{"id":"https://openalex.org/keywords/candida-parapsilosis","display_name":"Candida parapsilosis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/cyp51-inhibitors","display_name":"CYP51 inhibitors","score":0.8420000076293945},{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.7689999938011169},{"id":"https://openalex.org/keywords/cyp3a4-inhibition","display_name":"CYP3A4 inhibition","score":0.9459999799728394},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9459999799728394},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.5559999942779541},{"id":"https://openalex.org/keywords/virtual-screening","display_name":"virtual screening","score":0.7710000276565552},{"id":"https://openalex.org/keywords/homology-modeling","display_name":"homology modeling","score":0.8579999804496765},{"id":"https://openalex.org/keywords/1-2-4-triazole-derivatives","display_name":"1,2,4-triazole derivatives","score":0.8320000171661377}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9114999771118164},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.6298999786376953},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5105999708175659},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.3441999852657318},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3440999984741211},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.3366999924182892},{"id":"https://openalex.org/C2780315139","wikidata":"https://www.wikidata.org/wiki/Q419639","display_name":"Azole","level":3,"score":0.31690001487731934},{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.31029999256134033},{"id":"https://openalex.org/C2780690907","wikidata":"https://www.wikidata.org/wiki/Q412236","display_name":"Voriconazole","level":3,"score":0.28870001435279846},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.27810001373291016},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.27410000562667847},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.2567000091075897}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.molstruc.2026.147477","doi":"https://doi.org/10.1016/j.molstruc.2026.147477","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molstruc.2026.147477","pdf_url":null,"source":{"id":"https://openalex.org/S203479135","display_name":"Journal of Molecular Structure","issn_l":"0022-2860","issn":["0022-2860","1872-8014"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Structure","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4080388336","display_name":null,"funder_award_id":"THD-2020-18901","funder_id":"https://openalex.org/F4320323272","funder_display_name":"Hacettepe \u00dcniversitesi"},{"id":"https://openalex.org/G7813630204","display_name":null,"funder_award_id":"1/0686/23","funder_id":"https://openalex.org/F4320321779","funder_display_name":"Ministerstvo \u0161kolstva, vedy, v\u00fdskumu a \u0161portu Slovenskej republiky"},{"id":"https://openalex.org/G8739128697","display_name":null,"funder_award_id":"TOA-2023-3219","funder_id":"https://openalex.org/F4320327128","funder_display_name":"In\u00f6n\u00fc \u00dcniversitesi"}],"funders":[{"id":"https://openalex.org/F4320321779","display_name":"Ministerstvo \u0161kolstva, vedy, v\u00fdskumu a \u0161portu Slovenskej republiky","ror":"https://ror.org/044gwpv05"},{"id":"https://openalex.org/F4320323272","display_name":"Hacettepe \u00dcniversitesi","ror":"https://ror.org/04kwvgz42"},{"id":"https://openalex.org/F4320323641","display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV","ror":"https://ror.org/044gwpv05"},{"id":"https://openalex.org/F4320327128","display_name":"In\u00f6n\u00fc \u00dcniversitesi","ror":"https://ror.org/04asck240"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1851369101","https://openalex.org/W1969360633","https://openalex.org/W1971116820","https://openalex.org/W1985588649","https://openalex.org/W1988091937","https://openalex.org/W2000246385","https://openalex.org/W2004435637","https://openalex.org/W2012687726","https://openalex.org/W2024495825","https://openalex.org/W2029667189","https://openalex.org/W2031168104","https://openalex.org/W2038583777","https://openalex.org/W2051469879","https://openalex.org/W2055104860","https://openalex.org/W2059205366","https://openalex.org/W2074274985","https://openalex.org/W2093914988","https://openalex.org/W2104919283","https://openalex.org/W2112512902","https://openalex.org/W2119547517","https://openalex.org/W2132454074","https://openalex.org/W2132525235","https://openalex.org/W2132629607","https://openalex.org/W2142787097","https://openalex.org/W2517150559","https://openalex.org/W2588100751","https://openalex.org/W2593436234","https://openalex.org/W2593598577","https://openalex.org/W2611710196","https://openalex.org/W2737449748","https://openalex.org/W2902176449","https://openalex.org/W2936033307","https://openalex.org/W2938688137","https://openalex.org/W2946133706","https://openalex.org/W2954140842","https://openalex.org/W2954787706","https://openalex.org/W3024131549","https://openalex.org/W3032047811","https://openalex.org/W3083365648","https://openalex.org/W3084719377","https://openalex.org/W3113106398","https://openalex.org/W3167019654","https://openalex.org/W4210370823","https://openalex.org/W4211196614","https://openalex.org/W4225323859","https://openalex.org/W4289522338","https://openalex.org/W4375955690","https://openalex.org/W4376109027","https://openalex.org/W4387617416","https://openalex.org/W4387903904","https://openalex.org/W4401916766","https://openalex.org/W4404474131","https://openalex.org/W4409901056","https://openalex.org/W4410088525","https://openalex.org/W4411927841","https://openalex.org/W4414357406","https://openalex.org/W7117969953"],"related_works":["https://openalex.org/W3084719377","https://openalex.org/W2954787706","https://openalex.org/W2954140842","https://openalex.org/W4304845762","https://openalex.org/W334028295","https://openalex.org/W4396691845","https://openalex.org/W3131089458","https://openalex.org/W3002981942","https://openalex.org/W3175136870","https://openalex.org/W4315778365"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-08-29T00:00:00"}