{"id":"https://openalex.org/W7204522133","doi":"https://doi.org/10.3791/71894","title":"Association of Omega-3 PUFA Oral Nutritional Supplementation with Hematological and Nutritional Status in Discharged Malnourished GI Cancer Patients","display_name":"Association of Omega-3 PUFA Oral Nutritional Supplementation with Hematological and Nutritional Status in Discharged Malnourished GI Cancer Patients","publication_year":2026,"publication_date":"2026-08-28","ids":{"openalex":"https://openalex.org/W7204522133","doi":"https://doi.org/10.3791/71894","pmid":"https://pubmed.ncbi.nlm.nih.gov/42667193"},"language":"en","primary_location":{"id":"doi:10.3791/71894","doi":"https://doi.org/10.3791/71894","is_oa":false,"landing_page_url":"https://doi.org/10.3791/71894","pdf_url":null,"source":{"id":"https://openalex.org/S199738284","display_name":"Journal of Visualized Experiments","issn_l":"1940-087X","issn":["1940-087X","2834-8400"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320416","host_organization_name":"MyJOVE","host_organization_lineage":["https://openalex.org/P4310320416"],"host_organization_lineage_names":["MyJOVE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Visualized Experiments","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148520491","display_name":"Shi-Wei Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I4210101660","display_name":"Ningbo No. 2 Hospital","ror":"https://ror.org/01apc5d07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210101660","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shi-Wei Hu","raw_affiliation_strings":["Department of Clinical Nutrition, Ningbo No. 2 Hospital, Wenzhou Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Nutrition, Ningbo No. 2 Hospital, Wenzhou Medical University","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I4210101660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068062335","display_name":"Stuart McDonald","orcid":"https://orcid.org/0000-0001-6561-1927","observed_orcids":["https://orcid.org/0000-0001-6561-1927"]},"institutions":[{"id":"https://openalex.org/I13591777","display_name":"University of Nottingham Ningbo China","ror":"https://ror.org/03y4dt428","country_code":"CN","type":"education","lineage":["https://openalex.org/I13591777","https://openalex.org/I142263535"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Stuart McDonald","raw_affiliation_strings":["Smart Medicine Laboratory, Faculty of Humanities and Social Sciences, University of Nottingham Ningbo China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Smart Medicine Laboratory, Faculty of Humanities and Social Sciences, University of Nottingham Ningbo China","institution_ids":["https://openalex.org/I13591777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122892866","display_name":"Zeng-Bao Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405278839","display_name":"Yantai Institute of Technology","ror":"https://ror.org/00mh3mk36","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405278839"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zeng-Bao Hu","raw_affiliation_strings":["School of Accounting and Finance, Yantai Institute of Technology; zbhu@yitsd.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Accounting and Finance, Yantai Institute of Technology; zbhu@yitsd.edu.cn","institution_ids":["https://openalex.org/I4405278839"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5148472639","display_name":"Hua Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I4210101660","display_name":"Ningbo No. 2 Hospital","ror":"https://ror.org/01apc5d07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210101660","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua Yu","raw_affiliation_strings":["Department of Clinical Nutrition, Ningbo No. 2 Hospital, Wenzhou Medical University; yuhua13867869182@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Nutrition, Ningbo No. 2 Hospital, Wenzhou Medical University; yuhua13867869182@163.com","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I4210101660"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.67801971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"234","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.7095000147819519,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.7095000147819519,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.09889999777078629,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.07880000025033951,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/omega-3-polyunsaturated-fatty-acids","display_name":"omega-3 polyunsaturated fatty acids","score":0.9879999756813049},{"id":"https://openalex.org/keywords/oral-nutritional-supplementation","display_name":"oral nutritional supplementation","score":0.9819999933242798},{"id":"https://openalex.org/keywords/malnutrition","display_name":"malnutrition","score":0.7229999899864197},{"id":"https://openalex.org/keywords/gastrointestinal-cancer","display_name":"gastrointestinal cancer","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hematological-parameters","display_name":"hematological parameters","score":0.6880000233650208},{"id":"https://openalex.org/keywords/nutritional-status","display_name":"nutritional status","score":0.7699999809265137},{"id":"https://openalex.org/keywords/myeloprotection","display_name":"myeloprotection","score":0.8709999918937683},{"id":"https://openalex.org/keywords/neutrophil-to-lymphocyte-ratio","display_name":"neutrophil-to-lymphocyte ratio","score":0.859000027179718},{"id":"https://openalex.org/keywords/platelet-to-lymphocyte-ratio","display_name":"platelet-to-lymphocyte ratio","score":0.8920000195503235},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.8190000057220459},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.8389999866485596},{"id":"https://openalex.org/keywords/prognostic-nutritional-index","display_name":"prognostic nutritional index","score":0.9649999737739563},{"id":"https://openalex.org/keywords/weight-outcomes","display_name":"weight outcomes","score":0.5120000243186951},{"id":"https://openalex.org/keywords/cancer-survivors","display_name":"cancer survivors","score":0.3919999897480011}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8823000192642212},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6331999897956848},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5888000130653381},{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.36890000104904175},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.32829999923706055},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.32659998536109924},{"id":"https://openalex.org/C551997983","wikidata":"https://www.wikidata.org/wiki/Q12167","display_name":"Malnutrition","level":2,"score":0.31200000643730164},{"id":"https://openalex.org/C2908924572","wikidata":"https://www.wikidata.org/wiki/Q645858","display_name":"Nutritional Supplementation","level":2,"score":0.28610000014305115},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.27489998936653137},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2621000111103058},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.2572000026702881}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":true},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009752","descriptor_name":"Nutritional Status","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009752","descriptor_name":"Nutritional Status","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044342","descriptor_name":"Malnutrition","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D044342","descriptor_name":"Malnutrition","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D044342","descriptor_name":"Malnutrition","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":true},{"descriptor_ui":"D044342","descriptor_name":"Malnutrition","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":true},{"descriptor_ui":"D044342","descriptor_name":"Malnutrition","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D044342","descriptor_name":"Malnutrition","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.3791/71894","doi":"https://doi.org/10.3791/71894","is_oa":false,"landing_page_url":"https://doi.org/10.3791/71894","pdf_url":null,"source":{"id":"https://openalex.org/S199738284","display_name":"Journal of Visualized Experiments","issn_l":"1940-087X","issn":["1940-087X","2834-8400"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320416","host_organization_name":"MyJOVE","host_organization_lineage":["https://openalex.org/P4310320416"],"host_organization_lineage_names":["MyJOVE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Visualized Experiments","raw_type":"journal-article"},{"id":"pmid:42667193","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42667193","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of visualized experiments : JoVE","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.8697865605354309}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"/L;":[0],"95%":[1,19],"CI,":[2,20],"0.30-1.64;":[3],"P":[4,22],"=":[5,23],"0.005).":[6],"Adjusted":[7],"NLR":[8],"was":[9,49],"also":[10],"higher":[11],"in":[12,68],"the":[13],"ONS":[14,48],"group":[15],"(adjusted":[16],"difference,":[17],"0.60;":[18],"0.07-1.13;":[21],"0.028),":[24],"whereas":[25],"PLT,":[26],"C-reactive":[27],"protein":[28],"(CRP),":[29],"PLR,":[30],"SII,":[31],"albumin":[32],"(ALB),":[33],"and":[34,56],"prognostic":[35],"nutritional":[36],"index":[37],"(PNI)":[38],"did":[39],"not":[40,63],"differ":[41],"significantly.":[42],"Thus,":[43],"receipt":[44],"of":[45],"omega-3":[46],"PUFA-enriched":[47],"associated":[50],"with":[51,64],"a":[52,65],"potential":[53],"myeloprotective":[54],"effect":[55],"more":[57],"favorable":[58],"short-term":[59],"weight":[60],"outcomes,":[61],"but":[62],"consistent":[66],"reduction":[67],"systemic":[69],"inflammation.":[70]},"counts_by_year":[],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2026-08-29T00:00:00"}