{"id":"https://openalex.org/W7204497453","doi":"https://doi.org/10.51559/jcmid.v6i1.113","title":"Association between clinical outcomes of neonatal sepsis and microbial patterns and antibiotic resistance at Bali Mandara General Hospital, January\u2013December 2024","display_name":"Association between clinical outcomes of neonatal sepsis and microbial patterns and antibiotic resistance at Bali Mandara General Hospital, January\u2013December 2024","publication_year":2026,"publication_date":"2026-05-25","ids":{"openalex":"https://openalex.org/W7204497453","doi":"https://doi.org/10.51559/jcmid.v6i1.113"},"language":"en","primary_location":{"id":"doi:10.51559/jcmid.v6i1.113","doi":"https://doi.org/10.51559/jcmid.v6i1.113","is_oa":true,"landing_page_url":"https://doi.org/10.51559/jcmid.v6i1.113","pdf_url":"https://jcmid.id/index.php/JCMID/article/download/113/76","source":{"id":"https://openalex.org/S4387288455","display_name":"Journal of Clinical Microbiology and Infectious Diseases","issn_l":"2808-9405","issn":["2808-9405"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology and Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jcmid.id/index.php/JCMID/article/download/113/76","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5119853283","display_name":"Komang Nicko Juliasa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801684955","display_name":"Masaka Hospital","ror":"https://ror.org/01q0yhx95","country_code":"UG","type":"healthcare","lineage":["https://openalex.org/I2801684955"]},{"id":"https://openalex.org/I4210156068","display_name":"Bendigo Hospital","ror":"https://ror.org/0581hjr43","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210156068"]}],"countries":["AU","UG"],"is_corresponding":false,"raw_author_name":"Komang Nicko Juliasa","raw_affiliation_strings":["Pediatric Intern, Bali Mandara Hospital, Bali"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Intern, Bali Mandara Hospital, Bali","institution_ids":["https://openalex.org/I2801684955","https://openalex.org/I4210156068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078144449","display_name":"Luh Gde Ayu Pramitha Dewi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luh Gde Ayu Pramitha Dewi","raw_affiliation_strings":["Pediatrician, Bali Mandara Hospital, Bali"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrician, Bali Mandara Hospital, Bali","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040719168","display_name":"I Wayan Agus Gede Manik Saputra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801684955","display_name":"Masaka Hospital","ror":"https://ror.org/01q0yhx95","country_code":"UG","type":"healthcare","lineage":["https://openalex.org/I2801684955"]},{"id":"https://openalex.org/I4210156068","display_name":"Bendigo Hospital","ror":"https://ror.org/0581hjr43","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210156068"]}],"countries":["AU","UG"],"is_corresponding":false,"raw_author_name":"I Wayan Agus Gede Manik Saputra","raw_affiliation_strings":["Microbiologist, Bali Mandara Hospital, Bali"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiologist, Bali Mandara Hospital, Bali","institution_ids":["https://openalex.org/I2801684955","https://openalex.org/I4210156068"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033181322","display_name":"Ida Ayu Sri Kusuma Dewi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ida Ayu Sri Kusuma Dewi","raw_affiliation_strings":["Pediatrician, Bali Mandara Hospital, Bali"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrician, Bali Mandara Hospital, Bali","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"1","first_page":"34","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11961","display_name":"Neonatal and Maternal Infections","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11961","display_name":"Neonatal and Maternal Infections","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neonatal-sepsis","display_name":"neonatal sepsis","score":1.0},{"id":"https://openalex.org/keywords/carbapenem-resistant-acinetobacter-baumannii","display_name":"carbapenem-resistant Acinetobacter baumannii","score":0.9779999852180481},{"id":"https://openalex.org/keywords/klebsiella-pneumoniae","display_name":"Klebsiella pneumoniae","score":0.9990000128746033},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.9110000133514404},{"id":"https://openalex.org/keywords/neonatal-mortality","display_name":"neonatal mortality","score":0.8100000023841858},{"id":"https://openalex.org/keywords/gram-negative-bacteria","display_name":"Gram-negative bacteria","score":0.6850000023841858},{"id":"https://openalex.org/keywords/gestational-age","display_name":"gestational age","score":0.8169999718666077},{"id":"https://openalex.org/keywords/neonatal-intensive-care","display_name":"neonatal intensive care","score":0.6990000009536743},{"id":"https://openalex.org/keywords/antimicrobial-stewardship","display_name":"antimicrobial stewardship","score":0.8640000224113464},{"id":"https://openalex.org/keywords/empirical-antibiotic-therapy","display_name":"empirical antibiotic therapy","score":0.703000009059906},{"id":"https://openalex.org/keywords/infection-control","display_name":"infection control","score":0.8610000014305115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.842199981212616},{"id":"https://openalex.org/C2775953899","wikidata":"https://www.wikidata.org/wiki/Q6993495","display_name":"Neonatal sepsis","level":3,"score":0.7590000033378601},{"id":"https://openalex.org/C2776315533","wikidata":"https://www.wikidata.org/wiki/Q3241189","display_name":"Acinetobacter baumannii","level":4,"score":0.7013999819755554},{"id":"https://openalex.org/C2777427914","wikidata":"https://www.wikidata.org/wiki/Q408529","display_name":"Amikacin","level":3,"score":0.666100025177002},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.5831000208854675},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5080999732017517},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.490200012922287},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.4779999852180481},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.42980000376701355},{"id":"https://openalex.org/C2777091541","wikidata":"https://www.wikidata.org/wiki/Q9008292","display_name":"Neonatal intensive care unit","level":2,"score":0.40380001068115234},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3716999888420105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36660000681877136},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.36309999227523804},{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.3416000008583069},{"id":"https://openalex.org/C2778806431","wikidata":"https://www.wikidata.org/wiki/Q4774539","display_name":"Antibiotic sensitivity","level":3,"score":0.28949999809265137},{"id":"https://openalex.org/C2778523567","wikidata":"https://www.wikidata.org/wiki/Q310457","display_name":"Acinetobacter","level":3,"score":0.28040000796318054},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.2784999907016754},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.2515000104904175}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.51559/jcmid.v6i1.113","doi":"https://doi.org/10.51559/jcmid.v6i1.113","is_oa":true,"landing_page_url":"https://doi.org/10.51559/jcmid.v6i1.113","pdf_url":"https://jcmid.id/index.php/JCMID/article/download/113/76","source":{"id":"https://openalex.org/S4387288455","display_name":"Journal of Clinical Microbiology and Infectious Diseases","issn_l":"2808-9405","issn":["2808-9405"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology and Infectious Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.51559/jcmid.v6i1.113","doi":"https://doi.org/10.51559/jcmid.v6i1.113","is_oa":true,"landing_page_url":"https://doi.org/10.51559/jcmid.v6i1.113","pdf_url":"https://jcmid.id/index.php/JCMID/article/download/113/76","source":{"id":"https://openalex.org/S4387288455","display_name":"Journal of Clinical Microbiology and Infectious Diseases","issn_l":"2808-9405","issn":["2808-9405"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology and Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204497453.pdf","grobid_xml":"https://content.openalex.org/works/W7204497453.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W2097934856","https://openalex.org/W2168879097","https://openalex.org/W2333381374","https://openalex.org/W2520003227","https://openalex.org/W3215606468","https://openalex.org/W4319753172","https://openalex.org/W4323047337","https://openalex.org/W4389222587","https://openalex.org/W4399288223","https://openalex.org/W4400027227","https://openalex.org/W4405782932","https://openalex.org/W4407842185","https://openalex.org/W4414104653","https://openalex.org/W4415366163"],"related_works":["https://openalex.org/W4406222214","https://openalex.org/W4402461983","https://openalex.org/W4414561479","https://openalex.org/W2954837309","https://openalex.org/W7219544264","https://openalex.org/W4388814684","https://openalex.org/W4407754467","https://openalex.org/W7206156417","https://openalex.org/W7223004135","https://openalex.org/W4415209955"],"abstract_inverted_index":{"Background:":[0],"Neonatal":[1],"sepsis":[2,56,192],"remains":[3],"a":[4,206],"major":[5],"cause":[6],"of":[7,68,190],"morbidity":[8],"and":[9,31,57,65,84,103,129,143,148,183,193,223],"mortality":[10],"globally,":[11],"particularly":[12,180],"in":[13,116,154,158,227],"low-resource":[14],"settings":[15],"where":[16],"antimicrobial":[17,196,218],"resistance":[18],"is":[19],"increasing.":[20],"This":[21],"study":[22,46],"aimed":[23],"to":[24,62,75,94,141],"identify":[25],"microbial":[26],"patterns,":[27],"assess":[28,95],"antibiotic":[29,80,136],"resistance,":[30,137],"analyse":[32],"their":[33],"association":[34,97],"with":[35,54,138,172],"clinical":[36,85],"outcomes":[37,86,173],"among":[38],"neonates":[39,50,156],"treated":[40],"for":[41,216],"sepsis.":[42],"Methods:":[43],"A":[44],"cross-sectional":[45],"was":[47,92,152,169],"conducted":[48],"on":[49],"aged":[51],"0\u201328":[52],"days":[53],"suspected":[55],"positive":[58],"culture":[59,101],"results":[60],"admitted":[61],"the":[63,96,117,187,214],"NICU":[64,228],"Perinatology":[66],"Unit":[67],"Bali":[69],"Mandara":[70],"General":[71],"Hospital":[72],"from":[73],"January":[74],"December":[76],"2024.":[77],"Microbial":[78],"isolates,":[79],"susceptibility,":[81],"demographic":[82],"characteristics,":[83],"were":[87,108,112,186],"analysed.":[88],"Pearson\u2019s":[89],"Chi-square":[90],"test":[91],"used":[93],"between":[98],"Acinetobacter":[99,125],"baumannii":[100,126,182,203],"positivity":[102],"neonatal":[104,191],"outcomes.":[105],"Results:":[106],"There":[107,111],"75":[109,113],"samples":[110,114],"included":[115],"final":[118],"analysis.":[119],"Gram-negative":[120,178],"bacteria":[121],"predominate,":[122],"mainly":[123],"carbapenem-resistant":[124],"(CRAB)":[127],"(37.3%)":[128],"Klebsiella":[130],"pneumoniae":[131],"(24.0%).":[132],"CRAB":[133],"showed":[134,205],"extensive":[135],"residual":[139],"susceptibility":[140],"amikacin":[142],"trimethoprim-sulfamethoxazole.":[144],"Overall,":[145],"78.7%":[146],"improved":[147],"21.3%":[149],"died.":[150],"Mortality":[151],"higher":[153,210],"CRAB-positive":[155],"than":[157],"non-CRAB":[159],"cases":[160],"(35.8%":[161],"vs.":[162],"12.8%;":[163],"p":[164],"=":[165,175],"0.019).":[166],"Gestational":[167],"age":[168],"significantly":[170],"associated":[171],"(p":[174],"0.006).":[176],"Conclusion:":[177],"bacteria,":[179],"A.":[181,202],"K.":[184],"pneumoniae,":[185],"leading":[188],"causes":[189],"demonstrated":[194],"significant":[195],"resistance.":[197],"Although":[198],"not":[199],"statistically":[200],"significant,":[201],"infection":[204],"concerning":[207],"trend":[208],"toward":[209],"mortality.":[211],"Findings":[212],"highlight":[213],"need":[215],"strengthened":[217],"stewardship,":[219],"updated":[220],"empirical":[221],"therapy,":[222],"enhanced":[224],"infection-control":[225],"practices":[226],"settings.":[229]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-08-28T00:00:00"}