{"id":"https://openalex.org/W7204492535","doi":"https://doi.org/10.3390/clockssleep8030051","title":"Microvascular Disease in the Hippocampus in Obstructive Sleep Apnoea","display_name":"Microvascular Disease in the Hippocampus in Obstructive Sleep Apnoea","publication_year":2026,"publication_date":"2026-08-27","ids":{"openalex":"https://openalex.org/W7204492535","doi":"https://doi.org/10.3390/clockssleep8030051","pmid":"https://pubmed.ncbi.nlm.nih.gov/42783004"},"language":"en","primary_location":{"id":"doi:10.3390/clockssleep8030051","doi":"https://doi.org/10.3390/clockssleep8030051","is_oa":true,"landing_page_url":"https://doi.org/10.3390/clockssleep8030051","pdf_url":null,"source":{"id":"https://openalex.org/S4210215639","display_name":"Clocks & Sleep","issn_l":"2624-5175","issn":["2624-5175"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clocks & Sleep","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/clockssleep8030051","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012320570","display_name":"Cuicui Xu","orcid":"https://orcid.org/0000-0001-5345-8697","observed_orcids":["https://orcid.org/0000-0001-5345-8697"]},"institutions":[{"id":"https://openalex.org/I82951845","display_name":"RMIT University","ror":"https://ror.org/04ttjf776","country_code":"AU","type":"education","lineage":["https://openalex.org/I82951845"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Cuicui Xu","raw_affiliation_strings":["School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia"],"raw_orcid":"https://orcid.org/0000-0001-5345-8697","affiliations":[{"raw_affiliation_string":"School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia","institution_ids":["https://openalex.org/I82951845"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056869635","display_name":"Jessica E. Owen","orcid":"https://orcid.org/0000-0003-3318-9914","observed_orcids":["https://orcid.org/0000-0003-3318-9914"]},"institutions":[{"id":"https://openalex.org/I82951845","display_name":"RMIT University","ror":"https://ror.org/04ttjf776","country_code":"AU","type":"education","lineage":["https://openalex.org/I82951845"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jessica E. Owen","raw_affiliation_strings":["School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia"],"raw_orcid":"https://orcid.org/0000-0003-3318-9914","affiliations":[{"raw_affiliation_string":"School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia","institution_ids":["https://openalex.org/I82951845"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112819267","display_name":"T. Gislason","orcid":"https://orcid.org/0000-0002-6773-9876","observed_orcids":["https://orcid.org/0000-0002-6773-9876"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]},{"id":"https://openalex.org/I4210106610","display_name":"National University Hospital of Iceland","ror":"https://ror.org/011k7k191","country_code":"IS","type":"funder","lineage":["https://openalex.org/I4210106610"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Thorarinn Gislason","raw_affiliation_strings":["Department of Sleep, Landspitali\u2014The National University Hospital of Iceland, 101 Reykjavik, Iceland","Medical Faculty, University of Iceland, 101 Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sleep, Landspitali\u2014The National University Hospital of Iceland, 101 Reykjavik, Iceland","institution_ids":["https://openalex.org/I4210106610"]},{"raw_affiliation_string":"Medical Faculty, University of Iceland, 101 Reykjavik, Iceland","institution_ids":["https://openalex.org/I165368041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113653932","display_name":"Bryndis Benediktsdottir","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]},{"id":"https://openalex.org/I4210106610","display_name":"National University Hospital of Iceland","ror":"https://ror.org/011k7k191","country_code":"IS","type":"funder","lineage":["https://openalex.org/I4210106610"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Brynd\u00eds Benediktsd\u00f3ttir","raw_affiliation_strings":["Department of Sleep, Landspitali\u2014The National University Hospital of Iceland, 101 Reykjavik, Iceland","Medical Faculty, University of Iceland, 101 Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sleep, Landspitali\u2014The National University Hospital of Iceland, 101 Reykjavik, Iceland","institution_ids":["https://openalex.org/I4210106610"]},{"raw_affiliation_string":"Medical Faculty, University of Iceland, 101 Reykjavik, Iceland","institution_ids":["https://openalex.org/I165368041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004673580","display_name":"Ji\u2010Ming Ye","orcid":"https://orcid.org/0000-0003-3983-0098","observed_orcids":["https://orcid.org/0000-0003-3983-0098"]},"institutions":[{"id":"https://openalex.org/I82951845","display_name":"RMIT University","ror":"https://ror.org/04ttjf776","country_code":"AU","type":"education","lineage":["https://openalex.org/I82951845"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jiming Ye","raw_affiliation_strings":["School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia"],"raw_orcid":"https://orcid.org/0000-0003-3983-0098","affiliations":[{"raw_affiliation_string":"School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia","institution_ids":["https://openalex.org/I82951845"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047418672","display_name":"Stephen R. Robinson","orcid":"https://orcid.org/0000-0002-0987-0075","observed_orcids":["https://orcid.org/0000-0002-0987-0075"]},"institutions":[{"id":"https://openalex.org/I2800453128","display_name":"Austin Hospital","ror":"https://ror.org/010mv7n52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800453128","https://openalex.org/I4210163497"]},{"id":"https://openalex.org/I4210098456","display_name":"Institute for Breathing and Sleep","ror":"https://ror.org/00ymae584","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210098456"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]},{"id":"https://openalex.org/I82951845","display_name":"RMIT University","ror":"https://ror.org/04ttjf776","country_code":"AU","type":"education","lineage":["https://openalex.org/I82951845"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Stephen R. Robinson","raw_affiliation_strings":["Institute for Breathing and Sleep, Austin Health, Heidelberg, VIC 3084, Australia","School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Breathing and Sleep, Austin Health, Heidelberg, VIC 3084, Australia","institution_ids":["https://openalex.org/I2800453128","https://openalex.org/I4210098456","https://openalex.org/I4210163497"]},{"raw_affiliation_string":"School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, VIC 3083, Australia","institution_ids":["https://openalex.org/I82951845"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5047418672"],"corresponding_institution_ids":["https://openalex.org/I2800453128","https://openalex.org/I4210098456","https://openalex.org/I4210163497","https://openalex.org/I82951845"],"apc_list":{"value":1600,"currency":"CHF","value_usd":1930},"apc_paid":{"value":1600,"currency":"CHF","value_usd":1930},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.69291953,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"3","first_page":"51","last_page":"51"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.9520000219345093},{"id":"https://openalex.org/keywords/microvascular-disease","display_name":"microangiopathy","score":0.8600000143051147},{"id":"https://openalex.org/keywords/intermittent-hypoxia","display_name":"intermittent hypoxia","score":0.8569999933242798},{"id":"https://openalex.org/keywords/cerebral-ischemia","display_name":"cerebral ischemia","score":0.871999979019165},{"id":"https://openalex.org/keywords/continuous-positive-airway-pressure","display_name":"continuous positive airway pressure","score":0.9559999704360962},{"id":"https://openalex.org/keywords/osa-severity","display_name":"OSA severity","score":0.7129999995231628},{"id":"https://openalex.org/keywords/autopsy-tissue","display_name":"autopsy tissue","score":0.31299999356269836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8787000179290771},{"id":"https://openalex.org/C2779504383","wikidata":"https://www.wikidata.org/wiki/Q41482","display_name":"Autopsy","level":2,"score":0.7091000080108643},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.6104999780654907},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.589900016784668},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.5835000276565552},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5157999992370605},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.48489999771118164},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.4674000144004822},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4408999979496002},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.42829999327659607},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.42489999532699585},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.4140999913215637},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.39309999346733093},{"id":"https://openalex.org/C12722491","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microcirculation","level":2,"score":0.38190001249313354},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.36390000581741333},{"id":"https://openalex.org/C105922876","wikidata":"https://www.wikidata.org/wiki/Q1423981","display_name":"Airway","level":2,"score":0.35440000891685486},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.349700003862381},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3479999899864197},{"id":"https://openalex.org/C29374701","wikidata":"https://www.wikidata.org/wiki/Q1931388","display_name":"Cause of death","level":3,"score":0.33239999413490295},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.30570000410079956},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.30320000648498535},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.27549999952316284},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.2572000026702881},{"id":"https://openalex.org/C2780322006","wikidata":"https://www.wikidata.org/wiki/Q7539768","display_name":"Sleep study","level":4,"score":0.25380000472068787}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/clockssleep8030051","doi":"https://doi.org/10.3390/clockssleep8030051","is_oa":true,"landing_page_url":"https://doi.org/10.3390/clockssleep8030051","pdf_url":null,"source":{"id":"https://openalex.org/S4210215639","display_name":"Clocks & Sleep","issn_l":"2624-5175","issn":["2624-5175"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clocks & Sleep","raw_type":"journal-article"},{"id":"pmid:42783004","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42783004","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clocks & sleep","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:5c040524fb0f497a9ea7a13909a8e12c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/5c040524fb0f497a9ea7a13909a8e12c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clocks & Sleep, Vol 8, Iss 3, p 51 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13605731","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42783004/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clocks Sleep","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/clockssleep8030051","doi":"https://doi.org/10.3390/clockssleep8030051","is_oa":true,"landing_page_url":"https://doi.org/10.3390/clockssleep8030051","pdf_url":null,"source":{"id":"https://openalex.org/S4210215639","display_name":"Clocks & Sleep","issn_l":"2624-5175","issn":["2624-5175"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clocks & Sleep","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4377744495868683,"id":"https://metadata.un.org/sdg/14","display_name":"Life below water"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W10604852","https://openalex.org/W102965715","https://openalex.org/W1026160706","https://openalex.org/W1567524252","https://openalex.org/W1601599625","https://openalex.org/W1643525023","https://openalex.org/W1672716687","https://openalex.org/W1864807353","https://openalex.org/W1977657716","https://openalex.org/W1995299451","https://openalex.org/W1998887601","https://openalex.org/W2028963876","https://openalex.org/W2029454579","https://openalex.org/W2042592767","https://openalex.org/W2048900931","https://openalex.org/W2052742260","https://openalex.org/W2063003778","https://openalex.org/W2072602970","https://openalex.org/W2073748140","https://openalex.org/W2078239496","https://openalex.org/W2078799316","https://openalex.org/W2089245103","https://openalex.org/W2104901197","https://openalex.org/W2112861297","https://openalex.org/W2131895213","https://openalex.org/W2135921127","https://openalex.org/W2149747723","https://openalex.org/W2162294352","https://openalex.org/W2168958449","https://openalex.org/W2316606448","https://openalex.org/W2342464149","https://openalex.org/W2485924810","https://openalex.org/W2503056690","https://openalex.org/W2804440787","https://openalex.org/W2897668954","https://openalex.org/W2911293537","https://openalex.org/W2911746695","https://openalex.org/W2967540934","https://openalex.org/W3087583665","https://openalex.org/W3092521075","https://openalex.org/W3101249451","https://openalex.org/W3157460477","https://openalex.org/W3167047370","https://openalex.org/W3207372141","https://openalex.org/W4226239583","https://openalex.org/W4312019000","https://openalex.org/W4319337630","https://openalex.org/W4319873820","https://openalex.org/W4386127763","https://openalex.org/W4386968050","https://openalex.org/W4417316118","https://openalex.org/W7154686918","https://openalex.org/W7157275223"],"related_works":[],"abstract_inverted_index":{"Ischemia":[0],"is":[1,13,23,62,80],"a":[2,24],"primary":[3],"cause":[4],"of":[5,27,59,74,138,189],"microvascular":[6,60,190],"disease,":[7],"particularly":[8],"in":[9,37,134,151,184,192],"the":[10,32,57,135,139,152,187,193],"hippocampus,":[11],"which":[12,195],"unusually":[14],"vulnerable":[15],"to":[16,54,199,205],"hypoperfusion":[17],"and":[18,68,121,172,178],"hypoxia.":[19],"Since":[20],"intermittent":[21],"hypoxia":[22],"defining":[25],"feature":[26],"obstructive":[28],"sleep":[29],"apnoea":[30],"(OSA),":[31],"present":[33],"study":[34],"examined":[35],"microvessels":[36],"autopsy":[38,52],"tissue":[39],"from":[40],"patients":[41],"with":[42,64],"clinically":[43],"confirmed":[44],"OSA.":[45],"Immunohistochemistry":[46],"was":[47],"performed":[48],"on":[49],"30":[50],"hippocampal":[51],"samples":[53],"investigate":[55],"whether":[56,71],"incidence":[58],"abnormalities":[61,123,191],"associated":[63],"increased":[65],"OSA":[66,141,154],"severity,":[67],"if":[69],"so,":[70],"regular":[72,169],"use":[73],"continuous":[75],"positive":[76],"airway":[77],"pressure":[78],"(CPAP)":[79],"protective.":[81],"There":[82,163],"were":[83,164],"significantly":[84],"more":[85],"string":[86],"vessels":[87,99],"(4.3":[88],"\u00b1":[89,93,101,105,112,116,125,129,146,159],"0.9":[90,104],"vs.":[91,103,114,127],"1.7":[92],"0.4,":[94],"p":[95,107,118,131],"=":[96,108,119,132],"0.014),":[97],"narrowing":[98],"(3.5":[100],"1.0":[102],"0.3,":[106],"0.024),":[109],"strictures":[110],"(2.6":[111],"0.4":[113],"1.1":[115],"0.2,":[117],"0.002)":[120],"total":[122],"(10.3":[124],"1.5":[126],"3.7":[128,160],"0.6,":[130],"0.001)":[133],"CA1":[136],"subregion":[137],"moderate\u2013severe":[140,185],"group":[142,155],"(mean":[143,156],"ODI":[144,157],"35.9":[145],"6.4":[147],"events/h":[148,161],"sleep)":[149],"than":[150],"mild\u2013moderate":[153],"18.5":[158],"sleep).":[162],"no":[165],"significant":[166],"differences":[167],"between":[168,176],"CPAP":[170],"users":[171],"non-CPAP":[173],"users,":[174],"or":[175],"younger":[177],"older":[179],"individuals.":[180],"We":[181],"conclude":[182],"that":[183],"OSA,":[186],"preponderance":[188],"CA1,":[194],"are":[196],"too":[197],"narrow":[198],"carry":[200],"blood,":[201],"amplify":[202],"its":[203],"vulnerability":[204],"ischemia.":[206]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2026-08-28T00:00:00"}