{"id":"https://openalex.org/W7204455198","doi":"https://doi.org/10.2139/ssrn.7361251","title":"Reference gene instability in rough-toothed dolphins (Steno bredanensis) from a mercury-impacted environment: implications for molecular biomonitoring","display_name":"Reference gene instability in rough-toothed dolphins (Steno bredanensis) from a mercury-impacted environment: implications for molecular biomonitoring","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7204455198","doi":"https://doi.org/10.2139/ssrn.7361251"},"language":"en","primary_location":{"id":"doi:10.2139/ssrn.7361251","doi":"https://doi.org/10.2139/ssrn.7361251","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.7361251","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2139/ssrn.7361251","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148449557","display_name":"L\u00e9a Hayat","orcid":"https://orcid.org/0009-0006-8710-7282","observed_orcids":["https://orcid.org/0009-0006-8710-7282"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L\u00e9a Hayat","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-8710-7282","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005201195","display_name":"Annalisa Sambolino","orcid":"https://orcid.org/0000-0003-0231-1446","observed_orcids":["https://orcid.org/0000-0003-0231-1446"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Annalisa Sambolino","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0231-1446","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148414389","display_name":"Jan Hendrych","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan Hendrych","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091254416","display_name":"Pedro Ideia","orcid":"https://orcid.org/0000-0002-2178-2262","observed_orcids":["https://orcid.org/0000-0002-2178-2262"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pedro Ideia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002010518","display_name":"Ricardo Sousa","orcid":"https://orcid.org/0000-0002-5416-6570","observed_orcids":["https://orcid.org/0000-0002-5416-6570"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ricardo Sousa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083074922","display_name":"Filipe Alves","orcid":"https://orcid.org/0000-0003-3752-2745","observed_orcids":["https://orcid.org/0000-0003-3752-2745"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Filipe Alves","raw_affiliation_strings":["ARNET - Aquatic Research Network"],"raw_orcid":"https://orcid.org/0000-0003-3752-2745","affiliations":[{"raw_affiliation_string":"ARNET - Aquatic Research Network","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028862755","display_name":"N\u00e9lia C. Mestre","orcid":"https://orcid.org/0000-0001-6871-9984","observed_orcids":["https://orcid.org/0000-0001-6871-9984"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N\u00e9lia Mestre","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6871-9984","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5043387119","display_name":"C\u00e1rmen Sousa","orcid":"https://orcid.org/0000-0002-3483-1932","observed_orcids":["https://orcid.org/0000-0002-3483-1932"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Carmen de Sousa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5043387119"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.8726000189781189,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.8726000189781189,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.039799999445676804,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10659","display_name":"Marine animal studies overview","score":0.0333000011742115,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rough-toothed-dolphin","display_name":"rough-toothed dolphin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/steno-bredanensis","display_name":"Steno bredanensis","score":1.0},{"id":"https://openalex.org/keywords/mercury-bioaccumulation","display_name":"mercury bioaccumulation","score":0.8799999952316284},{"id":"https://openalex.org/keywords/reference-gene-validation","display_name":"reference gene validation","score":0.8149999976158142},{"id":"https://openalex.org/keywords/gene-expression-stability","display_name":"gene expression stability","score":0.8730000257492065},{"id":"https://openalex.org/keywords/ribosomal-protein-l4","display_name":"ribosomal protein L4","score":0.996999979019165},{"id":"https://openalex.org/keywords/skin-biopsy","display_name":"skin biopsy","score":0.7269999980926514},{"id":"https://openalex.org/keywords/northeast-atlantic","display_name":"Northeast Atlantic","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C109051061","wikidata":"https://www.wikidata.org/wiki/Q864610","display_name":"Biomonitoring","level":2,"score":0.7473000288009644},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7415000200271606},{"id":"https://openalex.org/C2779148672","wikidata":"https://www.wikidata.org/wiki/Q25326537","display_name":"Reference genes","level":4,"score":0.7404000163078308},{"id":"https://openalex.org/C2777095139","wikidata":"https://www.wikidata.org/wiki/Q4764975","display_name":"Sentinel species","level":2,"score":0.5910000205039978},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5293999910354614},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.5253000259399414},{"id":"https://openalex.org/C69991583","wikidata":"https://www.wikidata.org/wiki/Q1423575","display_name":"Candidate gene","level":3,"score":0.4950999915599823},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.4611999988555908},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.45260000228881836},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4523000121116638},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4316999912261963},{"id":"https://openalex.org/C140779682","wikidata":"https://www.wikidata.org/wiki/Q210868","display_name":"Sampling (signal processing)","level":3,"score":0.37619999051094055},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.36550000309944153},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3537999987602234},{"id":"https://openalex.org/C20719415","wikidata":"https://www.wikidata.org/wiki/Q416896","display_name":"Metallothionein","level":3,"score":0.3465000092983246},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.3391999900341034},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.3197999894618988},{"id":"https://openalex.org/C75917345","wikidata":"https://www.wikidata.org/wiki/Q2725298","display_name":"Sampling bias","level":3,"score":0.31610000133514404},{"id":"https://openalex.org/C2777777548","wikidata":"https://www.wikidata.org/wiki/Q206040","display_name":"Mercury (programming language)","level":2,"score":0.30709999799728394},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.2669999897480011},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.26190000772476196},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.25459998846054077}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2139/ssrn.7361251","doi":"https://doi.org/10.2139/ssrn.7361251","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.7361251","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.2139/ssrn.7361251","doi":"https://doi.org/10.2139/ssrn.7361251","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.7361251","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Life below water","id":"https://metadata.un.org/sdg/14","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1571283687","https://openalex.org/W1995416837","https://openalex.org/W2002900676","https://openalex.org/W2015693881","https://openalex.org/W2053114551","https://openalex.org/W2090298837","https://openalex.org/W2157198500","https://openalex.org/W2183963386","https://openalex.org/W2315236469","https://openalex.org/W2573209781","https://openalex.org/W2804079110","https://openalex.org/W2887265507","https://openalex.org/W2920072461","https://openalex.org/W2965712856","https://openalex.org/W3023609481","https://openalex.org/W3178042015","https://openalex.org/W4293018668","https://openalex.org/W4376273522"],"related_works":["https://openalex.org/W2072575940","https://openalex.org/W4365520232","https://openalex.org/W4388125187","https://openalex.org/W2056592781","https://openalex.org/W948606518","https://openalex.org/W7164762957","https://openalex.org/W2987803733","https://openalex.org/W2768597927","https://openalex.org/W2055798310","https://openalex.org/W4402167352"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-08-28T00:00:00"}