{"id":"https://openalex.org/W7204448500","doi":"https://doi.org/10.5281/zenodo.22132758","title":"Denominator selection bias in local genetic correlation: closed form, correction and diagnostic","display_name":"Denominator selection bias in local genetic correlation: closed form, correction and diagnostic","publication_year":2026,"publication_date":"2026-08-27","ids":{"openalex":"https://openalex.org/W7204448500","doi":"https://doi.org/10.5281/zenodo.22132758"},"language":"en","primary_location":{"id":"doi:10.5281/zenodo.22132758","doi":"https://doi.org/10.5281/zenodo.22132758","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22132758","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Software"},"volume":null,"type":"software","is_traditional":false,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.22132758","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148451113","display_name":"Riddhiman Jain","orcid":"https://orcid.org/0009-0005-9040-1039","observed_orcids":["https://orcid.org/0009-0005-9040-1039"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jain, Riddhiman","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0005-9040-1039","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5080314287","display_name":"Dana Paquin","orcid":"https://orcid.org/0000-0001-7928-4971","observed_orcids":["https://orcid.org/0000-0001-7928-4971"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paquin, Dana","raw_affiliation_strings":["Stanford University, Stanford, California, USA"],"raw_orcid":"https://orcid.org/0000-0001-7928-4971","affiliations":[{"raw_affiliation_string":"Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8574000000953674,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8574000000953674,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.10909999907016754,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/local-genetic-correlation","display_name":"local genetic correlation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/bias-correction","display_name":"bias correction","score":0.8830000162124634},{"id":"https://openalex.org/keywords/psychiatric-traits","display_name":"psychiatric traits","score":0.9229999780654907}],"concepts":[{"id":"https://openalex.org/C199163554","wikidata":"https://www.wikidata.org/wiki/Q1681619","display_name":"Univariate","level":3,"score":0.6560999751091003},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.6111000180244446},{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.5293999910354614},{"id":"https://openalex.org/C161890455","wikidata":"https://www.wikidata.org/wiki/Q1503548","display_name":"Heritability","level":2,"score":0.525600016117096},{"id":"https://openalex.org/C185429906","wikidata":"https://www.wikidata.org/wiki/Q1130160","display_name":"Estimator","level":2,"score":0.5218999981880188},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.49559998512268066},{"id":"https://openalex.org/C70616004","wikidata":"https://www.wikidata.org/wiki/Q5532885","display_name":"Genetic correlation","level":4,"score":0.484499990940094},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.47929999232292175},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.47110000252723694},{"id":"https://openalex.org/C2777735758","wikidata":"https://www.wikidata.org/wiki/Q817765","display_name":"Path (computing)","level":2,"score":0.4359000027179718},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.4336000084877014},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3831999897956848},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.3499000072479248},{"id":"https://openalex.org/C82793941","wikidata":"https://www.wikidata.org/wiki/Q1046024","display_name":"Path analysis (statistics)","level":2,"score":0.3230000138282776},{"id":"https://openalex.org/C19619285","wikidata":"https://www.wikidata.org/wiki/Q196372","display_name":"Observational error","level":2,"score":0.25440001487731934},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.25429999828338623},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.2500999867916107}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5281/zenodo.22132758","doi":"https://doi.org/10.5281/zenodo.22132758","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22132758","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Software"},{"id":"doi:10.5281/zenodo.22132759","doi":"https://doi.org/10.5281/zenodo.22132759","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22132759","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Software"},{"id":"doi:10.5281/zenodo.22830134","doi":"https://doi.org/10.5281/zenodo.22830134","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22830134","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Software"}],"best_oa_location":{"id":"doi:10.5281/zenodo.22132758","doi":"https://doi.org/10.5281/zenodo.22132758","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22132758","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Software"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7219146518","https://openalex.org/W46860604","https://openalex.org/W3119804512","https://openalex.org/W4413300048","https://openalex.org/W4388776988","https://openalex.org/W2800052801","https://openalex.org/W4220764353","https://openalex.org/W7154165921","https://openalex.org/W4404375854","https://openalex.org/W4412182487"],"abstract_inverted_index":{"LAVA":[0],"reports":[1],"a":[2,11,26,43],"local":[3],"genetic":[4],"correlation":[5],"only":[6],"where":[7],"both":[8,52],"traits":[9],"clear":[10],"univariate":[12],"heritability":[13],"filter":[14,20],"at":[15],"P":[16],"<":[17],"0.05.":[18],"The":[19],"acts":[21],"on":[22],"the":[23,37],"denominator":[24],"of":[25],"ratio":[27],"estimator":[28],"and":[29,46,50],"biases":[30],"every":[31],"surviving":[32],"estimate.":[33],"This":[34],"software":[35],"derives":[36],"bias":[38],"in":[39],"closed":[40],"form,":[41],"supplies":[42],"gate-aware":[44],"correction":[45],"an":[47],"applicability":[48],"diagnostic,":[49],"validates":[51],"against":[53],"LAVA's":[54],"own":[55],"code":[56],"path":[57],"across":[58],"six":[59],"psychiatric":[60],"trait":[61],"pairs.":[62]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-08-28T00:00:00"}