{"id":"https://openalex.org/W7204275606","doi":"https://doi.org/10.3389/fendo.2026.1870008","title":"Use of incretin receptor agonists in patients submitted to metabolic bariatric surgery \u2013 a systematic review and meta-analysis","display_name":"Use of incretin receptor agonists in patients submitted to metabolic bariatric surgery \u2013 a systematic review and meta-analysis","publication_year":2026,"publication_date":"2026-08-26","ids":{"openalex":"https://openalex.org/W7204275606","doi":"https://doi.org/10.3389/fendo.2026.1870008","pmid":"https://pubmed.ncbi.nlm.nih.gov/42718598"},"language":"en","primary_location":{"id":"doi:10.3389/fendo.2026.1870008","doi":"https://doi.org/10.3389/fendo.2026.1870008","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2026.1870008","pdf_url":"https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2026.1870008/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2026.1870008/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031304031","display_name":"Mariana Pereira Monteiro","orcid":"https://orcid.org/0000-0002-0662-1831","observed_orcids":["https://orcid.org/0000-0002-0662-1831"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Mariana Santos-Pereira","raw_affiliation_strings":["Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148285020","display_name":"Jo\u00e3o F. Frutuoso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Jo\u00e3o F. Frutuoso","raw_affiliation_strings":["Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100820142","display_name":"Sofia S. Pereira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Sofia S. Pereira","raw_affiliation_strings":["Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090181199","display_name":"Marta Guimar\u00e3es","orcid":"https://orcid.org/0000-0001-8094-7197","observed_orcids":["https://orcid.org/0000-0001-8094-7197"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4210091249","display_name":"Unidade Local de Sa\u00fade de Entre Douro e Vouga","ror":"https://ror.org/00d2ka202","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I4210091249"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Marta Guimar\u00e3es","raw_affiliation_strings":["Department of General Surgery, Hospital S\u00e3o Sebasti\u00e3o, Unidade Local de Sa\u00fade de Entre o Douro e Vouga","Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Hospital S\u00e3o Sebasti\u00e3o, Unidade Local de Sa\u00fade de Entre o Douro e Vouga","institution_ids":["https://openalex.org/I4210091249"]},{"raw_affiliation_string":"Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031304031","display_name":"Mariana Pereira Monteiro","orcid":"https://orcid.org/0000-0002-0662-1831","observed_orcids":["https://orcid.org/0000-0002-0662-1831"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Mariana P. Monteiro","raw_affiliation_strings":["Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Integrative and Translocation Research in Population Health (ITR), University of Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"Unit for Multidisciplinary Research in Biomedicine, School of Medicine and Biomedical Sciences,University of Porto","institution_ids":["https://openalex.org/I182534213"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.6103743,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":null,"first_page":"1870008","last_page":"1870008"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10569","display_name":"Bariatric Surgery and Outcomes","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10569","display_name":"Bariatric Surgery and Outcomes","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12173","display_name":"Body Contouring and Surgery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/incretin-receptor-agonists","display_name":"incretin receptor agonists","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bariatric-surgery","display_name":"bariatric surgery","score":0.9869999885559082},{"id":"https://openalex.org/keywords/liraglutide","display_name":"liraglutide","score":0.9340000152587891},{"id":"https://openalex.org/keywords/semaglutide","display_name":"semaglutide","score":1.0},{"id":"https://openalex.org/keywords/tirzepatide","display_name":"tirzepatide","score":1.0},{"id":"https://openalex.org/keywords/weight-regain","display_name":"weight regain","score":0.6629999876022339},{"id":"https://openalex.org/keywords/weight-loss-pharmacotherapy","display_name":"pharmacological weight loss","score":0.6890000104904175},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.4860000014305115},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.7599999904632568},{"id":"https://openalex.org/keywords/gastrointestinal-side-effects","display_name":"gastrointestinal adverse effects","score":0.796999990940094},{"id":"https://openalex.org/keywords/revisional-bariatric-surgery","display_name":"revisional bariatric surgery","score":0.8579999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8949999809265137},{"id":"https://openalex.org/C2781308992","wikidata":"https://www.wikidata.org/wiki/Q2526479","display_name":"Liraglutide","level":4,"score":0.8190000057220459},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.7983999848365784},{"id":"https://openalex.org/C2778881409","wikidata":"https://www.wikidata.org/wiki/Q1420402","display_name":"Incretin","level":4,"score":0.7821999788284302},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6643000245094299},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5138000249862671},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4424000084400177},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.40560001134872437},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.40070000290870667},{"id":"https://openalex.org/C2780533449","wikidata":"https://www.wikidata.org/wiki/Q417762","display_name":"Exenatide","level":4,"score":0.39820000529289246},{"id":"https://openalex.org/C2778586554","wikidata":"https://www.wikidata.org/wiki/Q550141","display_name":"Sleeve gastrectomy","level":5,"score":0.3903999924659729},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.3788999915122986},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35350000858306885},{"id":"https://openalex.org/C185280430","wikidata":"https://www.wikidata.org/wiki/Q14909910","display_name":"Glucagon-like peptide 1 receptor","level":4,"score":0.325300008058548},{"id":"https://openalex.org/C34320749","wikidata":"https://www.wikidata.org/wiki/Q17087302","display_name":"Weight management","level":4,"score":0.3158999979496002},{"id":"https://openalex.org/C2910182219","wikidata":"https://www.wikidata.org/wiki/Q357503","display_name":"Weight Loss Surgery","level":5,"score":0.29840001463890076},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.2671999931335449},{"id":"https://openalex.org/C2780320433","wikidata":"https://www.wikidata.org/wiki/Q3403879","display_name":"Weight gain","level":3,"score":0.26649999618530273},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.25619998574256897}],"mesh":[{"descriptor_ui":"D000069450","descriptor_name":"Liraglutide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000069450","descriptor_name":"Liraglutide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000069450","descriptor_name":"Liraglutide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000097789","descriptor_name":"Glucagon-Like Peptide-1 Receptor Agonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097789","descriptor_name":"Glucagon-Like Peptide-1 Receptor Agonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097789","descriptor_name":"Glucagon-Like Peptide-1 Receptor Agonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098860","descriptor_name":"Tirzepatide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098860","descriptor_name":"Tirzepatide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098860","descriptor_name":"Tirzepatide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000099194","descriptor_name":"Semaglutide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000099194","descriptor_name":"Semaglutide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000099194","descriptor_name":"Semaglutide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004763","descriptor_name":"Glucagon-Like Peptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004763","descriptor_name":"Glucagon-Like Peptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004763","descriptor_name":"Glucagon-Like Peptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D050110","descriptor_name":"Bariatric Surgery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D050110","descriptor_name":"Bariatric Surgery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D050110","descriptor_name":"Bariatric Surgery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054795","descriptor_name":"Incretins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D054795","descriptor_name":"Incretins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D054795","descriptor_name":"Incretins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3389/fendo.2026.1870008","doi":"https://doi.org/10.3389/fendo.2026.1870008","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2026.1870008","pdf_url":"https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2026.1870008/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},{"id":"pmid:42718598","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42718598","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13553220","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13553220/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13553220/pdf/fendo-17-1870008.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Endocrinol (Lausanne)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:be0dce371f93486a9bf00fd98f7b1a5a","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/be0dce371f93486a9bf00fd98f7b1a5a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Endocrinology, Vol 17 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fendo.2026.1870008","doi":"https://doi.org/10.3389/fendo.2026.1870008","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2026.1870008","pdf_url":"https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2026.1870008/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6883560419082642,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[{"id":"https://openalex.org/G4237192744","display_name":"Unidade Multidisciplinar de Investiga\u00e7\u00e3o Biom\u00e9dica - UMIB","funder_award_id":"UID/00215/2025","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G492460460","display_name":"Laborat\u00f3rio para a Investiga\u00e7\u00e3o Integrativa e translacional em Sa\u00fade Populacional","funder_award_id":"LA/P/0064/2020","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G5153181794","display_name":"Identifica\u00e7\u00e3o dos sinais e mecanismos moleculares associados \u00e0 fal\u00eancia terap\u00eautica da cirurgia bari\u00e1trica","funder_award_id":"PTDC/MEC-CIR/3615/2021","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G6997658380","display_name":null,"funder_award_id":"10.54499","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G8573502237","display_name":"Unidade Multidisciplinar de Investiga\u00e7\u00e3o Biom\u00e9dica - UMIB","funder_award_id":"UID/PRR2/00215/2025","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G8662145884","display_name":"Unidade Multidisciplinar de Investiga\u00e7\u00e3o Biom\u00e9dica - UMIB","funder_award_id":"UID/PRR/00215/2025","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"}],"funders":[{"id":"https://openalex.org/F4320321837","display_name":"Ministerio de Econom\u00eda y Competitividad","ror":"https://ror.org/034900433"},{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204275606.pdf","grobid_xml":"https://content.openalex.org/works/W7204275606.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1798757189","https://openalex.org/W1976372725","https://openalex.org/W2007518574","https://openalex.org/W2037154950","https://openalex.org/W2045485937","https://openalex.org/W2049384527","https://openalex.org/W2062675723","https://openalex.org/W2102175507","https://openalex.org/W2125435699","https://openalex.org/W2170892587","https://openalex.org/W2284097691","https://openalex.org/W2546249836","https://openalex.org/W2550011910","https://openalex.org/W2765286647","https://openalex.org/W2883923705","https://openalex.org/W2900742106","https://openalex.org/W2905443032","https://openalex.org/W2911639076","https://openalex.org/W2913427490","https://openalex.org/W2948337368","https://openalex.org/W2950088643","https://openalex.org/W3010254552","https://openalex.org/W3045296511","https://openalex.org/W3138431202","https://openalex.org/W3173575287","https://openalex.org/W3199001556","https://openalex.org/W4200213833","https://openalex.org/W4205898905","https://openalex.org/W4281934192","https://openalex.org/W4283702092","https://openalex.org/W4287833463","https://openalex.org/W4304080455","https://openalex.org/W4309844212","https://openalex.org/W4320032741","https://openalex.org/W4323035907","https://openalex.org/W4362458746","https://openalex.org/W4367668676","https://openalex.org/W4381618228","https://openalex.org/W4382046944","https://openalex.org/W4385264826","https://openalex.org/W4385852311","https://openalex.org/W4385879911","https://openalex.org/W4386710187","https://openalex.org/W4388419565","https://openalex.org/W4388965956","https://openalex.org/W4390572390","https://openalex.org/W4392346539","https://openalex.org/W4392369008","https://openalex.org/W4393043848","https://openalex.org/W4400415068","https://openalex.org/W4401379037","https://openalex.org/W4401556077","https://openalex.org/W4402404143","https://openalex.org/W4403226744","https://openalex.org/W4407165856","https://openalex.org/W4407445438","https://openalex.org/W4409205393","https://openalex.org/W4410277932","https://openalex.org/W4415018019"],"related_works":[],"abstract_inverted_index":{"Introduction:":[0],"Metabolic":[1],"bariatric":[2,75,101,142,218],"surgery":[3,102,219],"is":[4],"a":[5,11,17,48,153,169,229,237],"highly":[6],"effective":[7],"weight-loss":[8],"intervention.":[9],"Nevertheless,":[10],"non-negligible":[12],"proportion":[13],"of":[14,53,61,84,123,157,162,176,182,203],"patients":[15,70,138,235],"experience":[16],"suboptimal":[18,238],"clinical":[19,239],"response,":[20,240],"which":[21,124],"may":[22,243],"present":[23],"as":[24,184,245],"insufficient":[25],"weight":[26,29,38,91,146,155,174,226],"loss":[27,92,156,175,227],"or":[28,105],"regain":[30],"after":[31,216],"an":[32,246],"initial":[33],"loss.":[34,147],"In":[35],"these":[36,111,260],"cases,":[37],"management":[39],"pharmacotherapy":[40],"can":[41],"be":[42,263],"considered.":[43],"We":[44,78],"aimed":[45],"to":[46,73,99,186,223,250],"conduct":[47],"systematic":[49,121],"review":[50],"and":[51,67,82,93,161,194,241],"meta-analysis":[52],"the":[54,59,130,221,255],"best":[55],"available":[56],"data":[57,209],"on":[58],"use":[60],"incretin":[62,135,212],"receptor":[63,136,213],"agonists,":[64,137],"liraglutide,":[65],"semaglutide,":[66],"tirzepatide,":[68],"in":[69,96,119,129,172,180,234],"previously":[71],"submitted":[72,98],"metabolic":[74,100,141,217],"surgery.":[76,252],"Methods:":[77],"searched":[79],"PubMed,":[80],"Scopus,":[81],"Web":[83],"Science,":[85],"for":[86],"original":[87],"studies":[88],"that":[89,211],"evaluated":[90],"adverse":[94,190],"events":[95,191],"adults":[97],"one":[103],"year":[104],"more":[106],"before":[107],"receiving":[108],"treatment":[109,133,215],"with":[110,134,159,164,228,236,265],"drugs.":[112],"Results:":[113],"Twenty-seven":[114],"papers":[115],"(n=27)":[116],"were":[117,127,192,199],"included":[118],"this":[120],"review,":[122],"nineteen":[125],"(n=19)":[126],"used":[128],"meta-analysis.":[131],"After":[132],"who":[139],"underwent":[140],"surgery,":[143],"experienced":[144],"significant":[145,225],"Meta-analysis":[148],"showed,":[149],"at":[150],"12":[151],"months,":[152,168],"total":[154,173],"9.22%":[158],"liraglutide":[160],"9.02%":[163],"semaglutide.":[165,187],"At":[166],"6":[167],"mean":[170],"difference":[171],"4.23%":[177],"was":[178],"presented":[179],"favor":[181],"tirzepatide":[183],"compared":[185],"No":[188],"serious":[189],"observed":[193],"most":[195],"reported":[196],"side":[197],"effects":[198],"non-serious,":[200],"consisting":[201],"primarily":[202],"mild":[204],"gastrointestinal":[205],"symptoms.":[206],"Discussion:":[207],"This":[208],"suggests":[210],"agonist":[214],"demonstrated":[220],"ability":[222],"achieve":[224],"good":[230],"safety":[231],"profile,":[232],"particularly":[233],"thus":[242],"serve":[244],"alternative":[247],"rescue":[248],"therapy":[249],"revisional":[251],"However,":[253],"given":[254],"substantial":[256],"heterogeneity":[257],"across":[258],"studies,":[259],"findings":[261],"should":[262],"interpreted":[264],"caution.":[266],"Systematic":[267],"Review":[268],"Registration:":[269],"https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022371697,":[270],"identifier":[271],"CRD42022371697.":[272]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2026-08-27T00:00:00"}