{"id":"https://openalex.org/W7204259460","doi":"https://doi.org/10.1093/europace/euag228","title":"Outcomes of Amulet occluder implantation following Watchman screen failure in the ADVANCE LAA study: a real-world analysis of procedural success and safety","display_name":"Outcomes of Amulet occluder implantation following Watchman screen failure in the ADVANCE LAA study: a real-world analysis of procedural success and safety","publication_year":2026,"publication_date":"2026-08-25","ids":{"openalex":"https://openalex.org/W7204259460","doi":"https://doi.org/10.1093/europace/euag228","pmid":"https://pubmed.ncbi.nlm.nih.gov/42644716","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13554794"},"language":"en","primary_location":{"id":"doi:10.1093/europace/euag228","doi":"https://doi.org/10.1093/europace/euag228","is_oa":true,"landing_page_url":"https://doi.org/10.1093/europace/euag228","pdf_url":"https://academic.oup.com/europace/advance-article-pdf/doi/10.1093/europace/euag228/70797424/euag228.pdf","source":{"id":"https://openalex.org/S46732370","display_name":"EP Europace","issn_l":"1099-5129","issn":["1099-5129","1532-2092"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Europace","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/europace/advance-article-pdf/doi/10.1093/europace/euag228/70797424/euag228.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024164661","display_name":"Dhanunjaya Lakkireddy","orcid":"https://orcid.org/0000-0002-1492-2693","observed_orcids":["https://orcid.org/0000-0002-1492-2693"]},"institutions":[{"id":"https://openalex.org/I4405268027","display_name":"Kansas City Heart Rhythm Institute","ror":"https://ror.org/05f2yaa33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405268027"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dhanunjaya Lakkireddy","raw_affiliation_strings":["Kansas City Heart Rhythm Institute and Research Foundation , @ HCA Midwest, 5100 W 100th St, Suite-200, Overland Park, KS 66211, USA"],"raw_orcid":"https://orcid.org/0000-0002-1492-2693","affiliations":[{"raw_affiliation_string":"Kansas City Heart Rhythm Institute and Research Foundation , @ HCA Midwest, 5100 W 100th St, Suite-200, Overland Park, KS 66211, USA","institution_ids":["https://openalex.org/I4405268027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062850057","display_name":"Jacqueline Saw","orcid":"https://orcid.org/0000-0002-7027-984X","observed_orcids":["https://orcid.org/0000-0002-7027-984X"]},"institutions":[{"id":"https://openalex.org/I2802832906","display_name":"Vancouver General Hospital","ror":"https://ror.org/02zg69r60","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I141074466","https://openalex.org/I2799475292","https://openalex.org/I2802832906"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jacqueline Saw","raw_affiliation_strings":["Vancouver General Hospital , Vancouver, BC, USA"],"raw_orcid":"https://orcid.org/0000-0002-7027-984X","affiliations":[{"raw_affiliation_string":"Vancouver General Hospital , Vancouver, BC, USA","institution_ids":["https://openalex.org/I2802832906"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054200791","display_name":"Akash Makkar","orcid":"https://orcid.org/0009-0002-7922-2564","observed_orcids":["https://orcid.org/0009-0002-7922-2564"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akash Makkar","raw_affiliation_strings":["Arizona Heart Arrhythmia Associates , Phoenix AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arizona Heart Arrhythmia Associates , Phoenix AZ, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046438503","display_name":"Dipak Shah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dipak Shah","raw_affiliation_strings":["Heart Cardiology Consultants , Southfield, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Cardiology Consultants , Southfield, MI, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010082750","display_name":"Ruby Satpathy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ruby Satpathy","raw_affiliation_strings":["Baptist Heart Specialists , Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Baptist Heart Specialists , Jacksonville, FL, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059732839","display_name":"Muhamed Sari\u0107","orcid":"https://orcid.org/0000-0001-7682-3749","observed_orcids":["https://orcid.org/0000-0001-7682-3749"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Muhamed Saric","raw_affiliation_strings":["NYU Langone Health , New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NYU Langone Health , New York, NY, USA","institution_ids":["https://openalex.org/I4210086933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100684112","display_name":"Rahul Prakash Sharma","orcid":"https://orcid.org/0000-0002-8530-5035","observed_orcids":["https://orcid.org/0000-0002-8530-5035"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rahul Sharma","raw_affiliation_strings":["Cardiovascular Medicine , Stanford, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Medicine , Stanford, CA, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125300425","display_name":"Frank Cuoco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101226","display_name":"Charleston Museum","ror":"https://ror.org/018gqjy33","country_code":"US","type":"archive","lineage":["https://openalex.org/I4210101226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank Cuoco","raw_affiliation_strings":["Trident Medical Center , Charleston, SC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trident Medical Center , Charleston, SC, USA","institution_ids":["https://openalex.org/I4210101226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025985574","display_name":"Robert Lee Percell","orcid":"https://orcid.org/0000-0002-7356-2421","observed_orcids":["https://orcid.org/0000-0002-7356-2421"]},"institutions":[{"id":"https://openalex.org/I4210147348","display_name":"Northwestern Medicine","ror":"https://ror.org/04fzwnh64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Percell","raw_affiliation_strings":["Northwestern Medicine , Mchenry, IL, USA"],"raw_orcid":"https://orcid.org/0000-0002-7356-2421","affiliations":[{"raw_affiliation_string":"Northwestern Medicine , Mchenry, IL, USA","institution_ids":["https://openalex.org/I4210147348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064540383","display_name":"George E. Manoukian","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George Manoukian","raw_affiliation_strings":["Heart Rhythm Associates , Shenandoah, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Rhythm Associates , Shenandoah, TX, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092645817","display_name":"Ryan Gage","orcid":"https://orcid.org/0009-0006-4247-2163","observed_orcids":["https://orcid.org/0009-0006-4247-2163"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ryan Gage","raw_affiliation_strings":["Abbott Electrophysiology , Plymouth, MN, USA"],"raw_orcid":"https://orcid.org/0009-0006-4247-2163","affiliations":[{"raw_affiliation_string":"Abbott Electrophysiology , Plymouth, MN, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009858549","display_name":"Jordan A. Anderson","orcid":"https://orcid.org/0000-0002-6983-1019","observed_orcids":["https://orcid.org/0000-0002-6983-1019"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jordan A Anderson","raw_affiliation_strings":["Abbott Electrophysiology , Plymouth, MN, USA"],"raw_orcid":"https://orcid.org/0000-0002-6983-1019","affiliations":[{"raw_affiliation_string":"Abbott Electrophysiology , Plymouth, MN, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5125344063","display_name":"Himanshu Agarwal","orcid":"https://orcid.org/0009-0005-8849-2461","observed_orcids":["https://orcid.org/0009-0005-8849-2461"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]},{"id":"https://openalex.org/I2800482329","display_name":"CHI Health Creighton University Medical Center - Bergan Mercy","ror":"https://ror.org/03z1w3b90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800482329","https://openalex.org/I2802665030","https://openalex.org/I2802797007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Himanshu Agarwal","raw_affiliation_strings":["CHI Creighton University School of Medicine \u2013 Bergan Mercy Hospital , Omaha, NE , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHI Creighton University School of Medicine \u2013 Bergan Mercy Hospital , Omaha, NE , USA","institution_ids":["https://openalex.org/I114493937","https://openalex.org/I2800482329"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5024164661"],"corresponding_institution_ids":["https://openalex.org/I4405268027"],"apc_list":{"value":4344,"currency":"EUR","value_usd":4909},"apc_paid":{"value":4344,"currency":"EUR","value_usd":4909},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.6187639,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"9","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11579","display_name":"Cardiovascular and Diving-Related Complications","score":0.00839999970048666,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/watchman-device","display_name":"Watchman device","score":0.7680000066757202},{"id":"https://openalex.org/keywords/left-atrial-appendage-occlusion","display_name":"left atrial appendage closure","score":0.9819999933242798},{"id":"https://openalex.org/keywords/procedural-success","display_name":"procedural success","score":0.6340000033378601},{"id":"https://openalex.org/keywords/peri-device-leak","display_name":"peri-device leak","score":0.746999979019165},{"id":"https://openalex.org/keywords/procedural-safety","display_name":"procedural safety","score":0.597000002861023},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.5950000286102295},{"id":"https://openalex.org/keywords/major-bleeding","display_name":"major bleeding","score":0.9079999923706055},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.7229999899864197},{"id":"https://openalex.org/keywords/embolic-events","display_name":"embolic events","score":0.4729999899864197},{"id":"https://openalex.org/keywords/cha2ds2-vasc-score","display_name":"CHA2DS2-VASc score","score":0.8140000104904175},{"id":"https://openalex.org/keywords/has-bled-score","display_name":"HAS-BLED score","score":0.996999979019165},{"id":"https://openalex.org/keywords/transesophageal-echocardiography","display_name":"transesophageal echocardiography","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9592000246047974},{"id":"https://openalex.org/C2780434050","wikidata":"https://www.wikidata.org/wiki/Q6516934","display_name":"Left atrial appendage occlusion","level":4,"score":0.6574000120162964},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.6531000137329102},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5813000202178955},{"id":"https://openalex.org/C2781411149","wikidata":"https://www.wikidata.org/wiki/Q486975","display_name":"Implant","level":2,"score":0.5728999972343445},{"id":"https://openalex.org/C3017811039","wikidata":"https://www.wikidata.org/wiki/Q166019","display_name":"Major bleeding","level":3,"score":0.4966000020503998},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.47029998898506165},{"id":"https://openalex.org/C2776268601","wikidata":"https://www.wikidata.org/wiki/Q968808","display_name":"Occlusion","level":2,"score":0.4593000113964081},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.43790000677108765},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.39399999380111694},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.36820000410079956},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.31540000438690186},{"id":"https://openalex.org/C2778789114","wikidata":"https://www.wikidata.org/wiki/Q235007","display_name":"Cardiac surgery","level":2,"score":0.3068000078201294},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.2768000066280365},{"id":"https://openalex.org/C2780073493","wikidata":"https://www.wikidata.org/wiki/Q7523837","display_name":"Single Center","level":2,"score":0.27300000190734863},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.26759999990463257},{"id":"https://openalex.org/C2776805002","wikidata":"https://www.wikidata.org/wiki/Q614984","display_name":"Fluoroscopy","level":2,"score":0.26409998536109924},{"id":"https://openalex.org/C2779495589","wikidata":"https://www.wikidata.org/wiki/Q7916451","display_name":"Vascular closure device","level":3,"score":0.25429999828338623}],"mesh":[{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D000097546","descriptor_name":"Left Atrial Appendage Closure","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000097546","descriptor_name":"Left Atrial Appendage Closure","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D000097546","descriptor_name":"Left Atrial Appendage Closure","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D004617","descriptor_name":"Embolism","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011474","descriptor_name":"Prosthesis Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017548","descriptor_name":"Echocardiography, Transesophageal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D055989","descriptor_name":"Septal Occluder Device","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/europace/euag228","doi":"https://doi.org/10.1093/europace/euag228","is_oa":true,"landing_page_url":"https://doi.org/10.1093/europace/euag228","pdf_url":"https://academic.oup.com/europace/advance-article-pdf/doi/10.1093/europace/euag228/70797424/euag228.pdf","source":{"id":"https://openalex.org/S46732370","display_name":"EP Europace","issn_l":"1099-5129","issn":["1099-5129","1532-2092"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Europace","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13554794","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13554794/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13554794/pdf/euag228.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Europace","raw_type":"Text"},{"id":"pmid:42644716","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42644716","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/europace/euag228","doi":"https://doi.org/10.1093/europace/euag228","is_oa":true,"landing_page_url":"https://doi.org/10.1093/europace/euag228","pdf_url":"https://academic.oup.com/europace/advance-article-pdf/doi/10.1093/europace/euag228/70797424/euag228.pdf","source":{"id":"https://openalex.org/S46732370","display_name":"EP Europace","issn_l":"1099-5129","issn":["1099-5129","1532-2092"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Europace","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F5198060274","display_name":"Global Awards for Advancing Chronic Pain Research","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204259460.pdf","grobid_xml":"https://content.openalex.org/works/W7204259460.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7155407546","https://openalex.org/W4377015488","https://openalex.org/W4410521861","https://openalex.org/W4397031084","https://openalex.org/W3032688944","https://openalex.org/W3108131758","https://openalex.org/W4392468787","https://openalex.org/W4412726920","https://openalex.org/W6891595923","https://openalex.org/W2906632647"],"abstract_inverted_index":{"AIMS:":[0],"The":[1,25,36,101,214],"Watchman":[2,58,74,84,280],"device":[3],"is":[4,41],"widely":[5],"used":[6],"for":[7,73,81,286],"left":[8],"atrial":[9],"appendage":[10],"occlusion":[11],"but":[12],"may":[13,32],"be":[14],"unsuitable":[15],"in":[16,22,54,202,206,222,274],"patients":[17,55,71,79,150,166,205,275],"with":[18,28,276],"complex":[19,169,291],"anatomies,":[20],"resulting":[21],"screening":[23],"failures.":[24],"Amulet":[26,51,82,152,266],"occluder,":[27],"its":[29],"dual-seal":[30],"design,":[31],"overcome":[33],"these":[34,178],"limitations.":[35],"aim":[37],"of":[38,50,108,148,204,237],"this":[39],"analysis":[40,64],"to":[42,78],"evaluate":[43],"procedural":[44,89],"success,":[45],"closure,":[46],"and":[47,83,93,136,142,171,174,211,252,272,290],"clinical":[48,94,137],"outcomes":[49],"occluder":[52,267],"implantation":[53,153,268],"who":[56],"failed":[57,279],"screening.":[59],"METHODS":[60],"AND":[61],"RESULTS:":[62],"This":[63],"from":[65],"the":[66],"ADVANCE":[67],"LAA":[68],"study":[69],"included":[70],"ineligible":[72],"(Screen":[75,154],"Fail)":[76],"compared":[77],"eligible":[80],"(Device":[85],"Eligible).":[86],"Baseline":[87],"characteristics,":[88],"details,":[90],"cardiac":[91,120],"imaging,":[92],"events":[95,117,138],"were":[96,258],"assessed":[97],"through":[98],"1":[99],"year.":[100],"safety":[102,216],"endpoint":[103,217],"composite":[104,107,218],"was":[105,182,200,220,269],"a":[106,283],"all-cause":[109,253],"death,":[110],"ischaemic":[111],"stroke,":[112],"systemic":[113],"embolism,":[114],"or":[115,122,129,277],"device/procedure-related":[116],"requiring":[118],"open":[119],"surgery":[121],"major":[123,242],"endovascular":[124],"intervention":[125],"within":[126],"hospital":[127],"discharge":[128],"7":[130],"days":[131],"post-implant.":[132],"Independent":[133],"core":[134],"laboratory":[135],"committee":[139],"adjudicated":[140],"imaging":[141],"adverse":[143],"events,":[144],"respectively.":[145],"A":[146],"total":[147],"609":[149],"underwent":[151],"Fail:":[155],"n":[156,161],"=":[157,162,188,233],"97;":[158],"Device":[159],"Eligible:":[160],"512).":[163],"Screen":[164],"Fail":[165],"had":[167],"more":[168],"anatomy":[170],"higher":[172],"CHA2DS2-VASc":[173],"HAS-BLED":[175],"scores.":[176],"Despite":[177],"differences,":[179],"implant":[180,210],"success":[181],"high":[183],"(96.9%":[184],"vs.":[185,226,240,245,250,256],"98.0%;":[186],"P":[187,232],"0.446).":[189],"Clinically":[190],"relevant":[191],"closure":[192],"on":[193],"transoesophageal":[194],"echocardiography":[195],"(\u22643":[196],"mm":[197],"peri-device":[198],"leak)":[199],"achieved":[201],"\u226597%":[203],"both":[207,223,287],"groups":[208,224,261],"at":[209],"1-3":[212],"months.":[213],"peri-procedural":[215],"rate":[219],"similar":[221,259],"[3.1%":[225],"2.7%;":[227],"OR:":[228],"1.14":[229],"(0.32,":[230],"4.03);":[231],"0.742].":[234],"One-year":[235],"rates":[236],"stroke":[238],"(1.1%":[239],"1.0%),":[241],"bleeding":[243],"(9.6%":[244],"6.2%),":[246],"cardiovascular/unknown":[247],"death":[248,254],"(2.1%":[249],"5.2%),":[251],"(6.3%":[255],"6.6%)":[257],"between":[260],"(P":[262],">":[263],"0.05).":[264],"CONCLUSION:":[265],"feasible,":[270],"safe,":[271],"effective":[273],"without":[278],"screening,":[281],"providing":[282],"viable":[284],"option":[285],"anatomically":[288],"simple":[289],"anatomies.":[292],"CLINICAL":[293],"TRIAL":[294],"REGISTRATION:":[295],"URL":[296],"https://clinicaltrials.gov":[297],"Unique":[298],"Identifier":[299],"NCT05997446.":[300]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-08-27T00:00:00"}