{"id":"https://openalex.org/W7204247905","doi":"https://doi.org/10.1016/j.xocr.2026.100766","title":"When cholesteatoma breaches the dural barrier: A case report of congenital cholesteatoma presenting with seizure and facial paralysis","display_name":"When cholesteatoma breaches the dural barrier: A case report of congenital cholesteatoma presenting with seizure and facial paralysis","publication_year":2026,"publication_date":"2026-08-26","ids":{"openalex":"https://openalex.org/W7204247905","doi":"https://doi.org/10.1016/j.xocr.2026.100766"},"language":"en","primary_location":{"id":"doi:10.1016/j.xocr.2026.100766","doi":"https://doi.org/10.1016/j.xocr.2026.100766","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xocr.2026.100766","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2468548826000445/pdf","source":{"id":"https://openalex.org/S2898229552","display_name":"Otolaryngology Case Reports","issn_l":"2468-5488","issn":["2468-5488"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Otolaryngology Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2468548826000445/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5148253573","display_name":"Hacer Do\u011fantekin Uysal","orcid":"https://orcid.org/0009-0006-3688-070X","observed_orcids":["https://orcid.org/0009-0006-3688-070X"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Hacer Do\u011fantekin Uysal","raw_affiliation_strings":["Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0009-0006-3688-070X","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148236136","display_name":"Duygu \u0130yi","orcid":"https://orcid.org/0009-0008-8865-2914","observed_orcids":["https://orcid.org/0009-0008-8865-2914"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Duygu \u0130yi","raw_affiliation_strings":["Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055235454","display_name":"Eda Eyduran","orcid":"https://orcid.org/0000-0002-3696-7382","observed_orcids":["https://orcid.org/0000-0002-3696-7382"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Eda Eyduran","raw_affiliation_strings":["Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148326071","display_name":"Ay\u015fe Sena Kum","orcid":"https://orcid.org/0009-0006-2065-5292","observed_orcids":["https://orcid.org/0009-0006-2065-5292"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ay\u015fe Sena Kum","raw_affiliation_strings":["Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061957338","display_name":"\u0130rfan Yorulmaz","orcid":"https://orcid.org/0000-0001-8809-0327","observed_orcids":["https://orcid.org/0000-0001-8809-0327"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u0130rfan Yorulmaz","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-8809-0327","affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014336446","display_name":"G\u00fcl Arga","orcid":"https://orcid.org/0000-0002-4846-5945","observed_orcids":["https://orcid.org/0000-0002-4846-5945"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"G\u00fcl Arga","raw_affiliation_strings":["Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052579184","display_name":"Merve Havan","orcid":"https://orcid.org/0000-0003-3431-7906","observed_orcids":["https://orcid.org/0000-0003-3431-7906"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Merve Havan","raw_affiliation_strings":["Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016193506","display_name":"Hacer U\u00e7mak","orcid":"https://orcid.org/0000-0003-2927-2360","observed_orcids":["https://orcid.org/0000-0003-2927-2360"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Tan\u0131l Kendirli","raw_affiliation_strings":["Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0000-0003-2927-2360","affiliations":[{"raw_affiliation_string":"Division of Pediatric Intensive Care, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I149218525"],"apc_list":{"value":1110,"currency":"USD","value_usd":1110},"apc_paid":{"value":1110,"currency":"USD","value_usd":1110},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":null,"first_page":"100766","last_page":"100766"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10861","display_name":"Ear Surgery and Otitis Media","score":0.86080002784729,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10861","display_name":"Ear Surgery and Otitis Media","score":0.86080002784729,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14326","display_name":"Ear and Head Tumors","score":0.1014999970793724,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13738","display_name":"Congenital Ear and Nasal Anomalies","score":0.012400000356137753,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/congenital-cholesteatoma","display_name":"congenital cholesteatoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pachymeningitis","display_name":"pachymeningitis","score":0.9800000190734863},{"id":"https://openalex.org/keywords/generalized-tonic-clonic-seizures","display_name":"generalized tonic-clonic seizures","score":0.8140000104904175},{"id":"https://openalex.org/keywords/facial-paralysis","display_name":"facial paralysis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/otalgia","display_name":"otalgia","score":0.9369999766349792},{"id":"https://openalex.org/keywords/pediatric-cholesteatoma","display_name":"pediatric cholesteatoma","score":0.7850000262260437},{"id":"https://openalex.org/keywords/middle-ear-tumor","display_name":"middle ear tumor","score":0.5260000228881836},{"id":"https://openalex.org/keywords/ossicular-reconstruction","display_name":"ossicular reconstruction","score":0.7689999938011169},{"id":"https://openalex.org/keywords/intracranial-complications","display_name":"intracranial complications","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9485999941825867},{"id":"https://openalex.org/C2780725665","wikidata":"https://www.wikidata.org/wiki/Q558230","display_name":"Cholesteatoma","level":2,"score":0.8937000036239624},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.6488000154495239},{"id":"https://openalex.org/C2777846895","wikidata":"https://www.wikidata.org/wiki/Q501553","display_name":"Middle ear","level":2,"score":0.484499990940094},{"id":"https://openalex.org/C2781019609","wikidata":"https://www.wikidata.org/wiki/Q7562539","display_name":"Facial paralysis","level":2,"score":0.43549999594688416},{"id":"https://openalex.org/C2779618896","wikidata":"https://www.wikidata.org/wiki/Q107231","display_name":"Paralysis","level":2,"score":0.37770000100135803},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.3292999863624573},{"id":"https://openalex.org/C2778987478","wikidata":"https://www.wikidata.org/wiki/Q242160","display_name":"Facial nerve","level":2,"score":0.328000009059906},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.32739999890327454},{"id":"https://openalex.org/C86605331","wikidata":"https://www.wikidata.org/wiki/Q3617410","display_name":"Cerebellopontine angle","level":3,"score":0.3158999979496002},{"id":"https://openalex.org/C2780493683","wikidata":"https://www.wikidata.org/wiki/Q16035842","display_name":"Hearing loss","level":2,"score":0.3050999939441681},{"id":"https://openalex.org/C2777939775","wikidata":"https://www.wikidata.org/wiki/Q16313","display_name":"Temporal bone","level":2,"score":0.29660001397132874},{"id":"https://openalex.org/C2993523616","wikidata":"https://www.wikidata.org/wiki/Q17146697","display_name":"Neurological deficit","level":2,"score":0.2824000120162964},{"id":"https://openalex.org/C2780868646","wikidata":"https://www.wikidata.org/wiki/Q4462424","display_name":"Mastoidectomy","level":3,"score":0.2793000042438507}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.xocr.2026.100766","doi":"https://doi.org/10.1016/j.xocr.2026.100766","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xocr.2026.100766","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2468548826000445/pdf","source":{"id":"https://openalex.org/S2898229552","display_name":"Otolaryngology Case Reports","issn_l":"2468-5488","issn":["2468-5488"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Otolaryngology Case Reports","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.xocr.2026.100766","doi":"https://doi.org/10.1016/j.xocr.2026.100766","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xocr.2026.100766","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2468548826000445/pdf","source":{"id":"https://openalex.org/S2898229552","display_name":"Otolaryngology Case Reports","issn_l":"2468-5488","issn":["2468-5488"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Otolaryngology Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204247905.pdf","grobid_xml":"https://content.openalex.org/works/W7204247905.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W184361765","https://openalex.org/W1994376575","https://openalex.org/W2000709513","https://openalex.org/W2005153653","https://openalex.org/W2012607566","https://openalex.org/W2069603698","https://openalex.org/W2070633272","https://openalex.org/W2154962784","https://openalex.org/W2161342485","https://openalex.org/W2163475286","https://openalex.org/W2770728366","https://openalex.org/W4297497399","https://openalex.org/W4322702495"],"related_works":["https://openalex.org/W2326150964","https://openalex.org/W3015978147","https://openalex.org/W4399477356","https://openalex.org/W2788662382","https://openalex.org/W2007261692","https://openalex.org/W4393393553","https://openalex.org/W4402905442","https://openalex.org/W2808508928","https://openalex.org/W2112470189","https://openalex.org/W3091940155"],"abstract_inverted_index":{"Congenital":[0],"cholesteatoma":[1,82,99,134],"is":[2,126],"a":[3,44,60,80],"rare":[4],"pathology":[5],"originating":[6],"from":[7],"epithelial":[8],"cells":[9],"that":[10,138],"may":[11],"develop":[12],"in":[13],"the":[14,84,93,98,102,106,120,127],"middle":[15],"ear,":[16],"temporal":[17],"bone,":[18],"or":[19],"intracranially.":[20],"Initially":[21],"asymptomatic,":[22],"it":[23],"can":[24],"progress":[25],"to":[26,79,96,140,152],"cause":[27],"hearing":[28],"loss,":[29],"vertigo,":[30],"cerebrospinal":[31],"fluid":[32],"leakage,":[33],"cranial":[34],"neuropathies,":[35],"and":[36,64,100,111,142,146,156],"central":[37],"nervous":[38],"system":[39],"infections.":[40],"This":[41],"report":[42],"describes":[43],"unique":[45],"case":[46,130],"of":[47,122,131],"an":[48],"8-year-old":[49],"female":[50],"who":[51],"initially":[52],"presented":[53],"with":[54,136,161],"severe":[55],"left-sided":[56],"otalgia,":[57],"subsequently":[58],"developing":[59],"generalized":[61],"tonic-clonic":[62],"seizure":[63,69],"left":[65,94],"facial":[66,107],"paralysis.":[67],"The":[68],"event":[70],"prompted":[71],"urgent":[72],"diagnostic":[73],"workup,":[74],"which":[75],"revealed":[76],"pachymeningitis":[77],"secondary":[78],"congenital":[81,133],"breaching":[83],"dural":[85],"barrier.":[86],"Surgical":[87],"intervention":[88,149],"was":[89],"successfully":[90],"performed":[91],"on":[92],"ear":[95],"excise":[97],"reconstruct":[101],"ossicular":[103],"chain.":[104],"Postoperatively,":[105],"paralysis":[108],"gradually":[109],"resolved,":[110],"no":[112],"further":[113],"seizures":[114,141],"occurred":[115],"during":[116],"multidisciplinary":[117],"follow-up.":[118],"To":[119],"best":[121],"our":[123],"knowledge,":[124],"this":[125,162],"first":[128],"documented":[129],"pediatric":[132],"presenting":[135],"otalgia":[137],"progressed":[139],"pachymeningitis.":[143],"Early":[144],"diagnosis":[145],"prompt":[147],"surgical":[148],"are":[150],"imperative":[151],"prevent":[153],"permanent":[154],"sequelae":[155],"serious":[157],"intracranial":[158],"complications":[159],"associated":[160],"pathology.":[163]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-08-27T00:00:00"}