{"id":"https://openalex.org/W7204239074","doi":"https://doi.org/10.33380/2305-2066-2026-15-3-2323","title":"Study of the amino acid composition of raw material of Oxytropis pilosa (L.) DC., growing in the Saratov region","display_name":"Study of the amino acid composition of raw material of Oxytropis pilosa (L.) DC., growing in the Saratov region","publication_year":2026,"publication_date":"2026-08-26","ids":{"openalex":"https://openalex.org/W7204239074","doi":"https://doi.org/10.33380/2305-2066-2026-15-3-2323"},"language":"en","primary_location":{"id":"doi:10.33380/2305-2066-2026-15-3-2323","doi":"https://doi.org/10.33380/2305-2066-2026-15-3-2323","is_oa":true,"landing_page_url":"https://doi.org/10.33380/2305-2066-2026-15-3-2323","pdf_url":"https://www.pharmjournal.ru/jour/article/download/2446/1537","source":{"id":"https://openalex.org/S4210178334","display_name":"Drug development & registration","issn_l":"2305-2066","issn":["2305-2066","2658-5049"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug development & registration","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7204239074"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.pharmjournal.ru/jour/article/download/2446/1537","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015301344","display_name":"Ludmila V. Karavaeva","orcid":"https://orcid.org/0000-0003-1642-5399","observed_orcids":["https://orcid.org/0000-0003-1642-5399"]},"institutions":[{"id":"https://openalex.org/I4210118375","display_name":"Saratov State Medical University","ror":"https://ror.org/02jmkw435","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210118375"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"L. V. Karavaeva","raw_affiliation_strings":["Saratov State Medical University named after V. I. Razumovsky"],"raw_orcid":"https://orcid.org/0000-0003-1642-5399","affiliations":[{"raw_affiliation_string":"Saratov State Medical University named after V. I. Razumovsky","institution_ids":["https://openalex.org/I4210118375"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079783940","display_name":"Uliana Andreevna Matvienko","orcid":"https://orcid.org/0000-0002-1714-9165","observed_orcids":["https://orcid.org/0000-0002-1714-9165"]},"institutions":[{"id":"https://openalex.org/I4210118375","display_name":"Saratov State Medical University","ror":"https://ror.org/02jmkw435","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210118375"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"U. A. Matvienko","raw_affiliation_strings":["Saratov State Medical University named after V. I. Razumovsky"],"raw_orcid":"https://orcid.org/0000-0002-1714-9165","affiliations":[{"raw_affiliation_string":"Saratov State Medical University named after V. I. Razumovsky","institution_ids":["https://openalex.org/I4210118375"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050343857","display_name":"A. M. Poluyanov","orcid":"https://orcid.org/0000-0002-9960-6699","observed_orcids":["https://orcid.org/0000-0002-9960-6699"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. M. Poluyanov","raw_affiliation_strings":["I. M. Sechenov First Moscow State Medical University (Sechenov University)"],"raw_orcid":"https://orcid.org/0000-0002-9960-6699","affiliations":[{"raw_affiliation_string":"I. M. Sechenov First Moscow State Medical University (Sechenov University)","institution_ids":["https://openalex.org/I17877952"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029780027","display_name":"\u041d. \u0410. \u0414\u0443\u0440\u043d\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0003-4628-9519","observed_orcids":["https://orcid.org/0000-0003-4628-9519"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210118375","display_name":"Saratov State Medical University","ror":"https://ror.org/02jmkw435","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210118375"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. A. Durnova","raw_affiliation_strings":["I. M. Sechenov First Moscow State Medical University (Sechenov University)","Saratov State Medical University named after V. I. Razumovsky"],"raw_orcid":"https://orcid.org/0000-0003-4628-9519","affiliations":[{"raw_affiliation_string":"I. M. Sechenov First Moscow State Medical University (Sechenov University)","institution_ids":["https://openalex.org/I17877952"]},{"raw_affiliation_string":"Saratov State Medical University named after V. I. Razumovsky","institution_ids":["https://openalex.org/I4210118375"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"3","first_page":"207","last_page":"216"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.35989999771118164,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.35989999771118164,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11973","display_name":"Plant chemical constituents analysis","score":0.274399995803833,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14127","display_name":"Food Nutrient Composition and Product Development","score":0.2371000051498413,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxytropis-pilosa","display_name":"Oxytropis pilosa","score":0.9959999918937683},{"id":"https://openalex.org/keywords/amino-acid-composition","display_name":"amino acid composition","score":0.9829999804496765},{"id":"https://openalex.org/keywords/free-amino-acids","display_name":"free amino acids","score":0.9539999961853027},{"id":"https://openalex.org/keywords/bound-amino-acids","display_name":"bound amino acids","score":0.984000027179718},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.8529999852180481},{"id":"https://openalex.org/keywords/plant-raw-materials","display_name":"plant raw materials","score":0.734000027179718},{"id":"https://openalex.org/keywords/saratov-region","display_name":"Saratov region","score":0.6740000247955322},{"id":"https://openalex.org/keywords/herbs","display_name":"herbs","score":0.3400000035762787},{"id":"https://openalex.org/keywords/flowers","display_name":"flowers","score":0.8859999775886536},{"id":"https://openalex.org/keywords/leaves","display_name":"leaves","score":0.9900000095367432},{"id":"https://openalex.org/keywords/4-hydroxyproline","display_name":"4-hydroxyproline","score":0.8320000171661377},{"id":"https://openalex.org/keywords/aspartate","display_name":"aspartic acid","score":0.7570000290870667},{"id":"https://openalex.org/keywords/proline","display_name":"proline","score":0.8270000219345093},{"id":"https://openalex.org/keywords/alanine","display_name":"alanine","score":0.49799999594688416},{"id":"https://openalex.org/keywords/threonine","display_name":"threonine","score":0.628000020980835},{"id":"https://openalex.org/keywords/isoleucine","display_name":"isoleucine","score":0.7289999723434448},{"id":"https://openalex.org/keywords/valine","display_name":"valine","score":0.6230000257492065},{"id":"https://openalex.org/keywords/serine","display_name":"serine","score":0.9330000281333923},{"id":"https://openalex.org/keywords/hydrolysis","display_name":"hydrolysis","score":0.5139999985694885}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7882999777793884},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6047000288963318},{"id":"https://openalex.org/C206139338","wikidata":"https://www.wikidata.org/wiki/Q192355","display_name":"Raw material","level":2,"score":0.5446000099182129},{"id":"https://openalex.org/C40231798","wikidata":"https://www.wikidata.org/wiki/Q1333743","display_name":"Composition (language)","level":2,"score":0.5157999992370605},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.48809999227523804},{"id":"https://openalex.org/C2781213060","wikidata":"https://www.wikidata.org/wiki/Q49546","display_name":"Acetone","level":2,"score":0.4837999939918518},{"id":"https://openalex.org/C2776673659","wikidata":"https://www.wikidata.org/wiki/Q47512","display_name":"Acetic acid","level":2,"score":0.4334000051021576},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.4187000095844269},{"id":"https://openalex.org/C2777431362","wikidata":"https://www.wikidata.org/wiki/Q170545","display_name":"Phenylalanine","level":3,"score":0.4138000011444092},{"id":"https://openalex.org/C95986675","wikidata":"https://www.wikidata.org/wiki/Q185168","display_name":"Quantitative analysis (chemistry)","level":2,"score":0.39890000224113464},{"id":"https://openalex.org/C2780343419","wikidata":"https://www.wikidata.org/wiki/Q332084","display_name":"Spectrophotometry","level":2,"score":0.3628999888896942},{"id":"https://openalex.org/C3018587665","wikidata":"https://www.wikidata.org/wiki/Q7268696","display_name":"Qualitative analysis","level":3,"score":0.35830000042915344},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.35690000653266907},{"id":"https://openalex.org/C2778944976","wikidata":"https://www.wikidata.org/wiki/Q421098","display_name":"Ninhydrin","level":3,"score":0.34380000829696655},{"id":"https://openalex.org/C149849071","wikidata":"https://www.wikidata.org/wiki/Q1263816","display_name":"Chemical composition","level":2,"score":0.31709998846054077},{"id":"https://openalex.org/C33619061","wikidata":"https://www.wikidata.org/wiki/Q655346","display_name":"Atomic absorption spectroscopy","level":2,"score":0.30809998512268066},{"id":"https://openalex.org/C180370935","wikidata":"https://www.wikidata.org/wiki/Q898473","display_name":"Paper chromatography","level":2,"score":0.2987000048160553},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.28040000796318054},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.2712000012397766},{"id":"https://openalex.org/C2993070364","wikidata":"https://www.wikidata.org/wiki/Q3142557","display_name":"Amino acid analysis","level":3,"score":0.2689000070095062},{"id":"https://openalex.org/C67031304","wikidata":"https://www.wikidata.org/wiki/Q274579","display_name":"Preservative","level":2,"score":0.26100000739097595},{"id":"https://openalex.org/C39699697","wikidata":"https://www.wikidata.org/wiki/Q869095","display_name":"Brewing","level":3,"score":0.2549000084400177}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.33380/2305-2066-2026-15-3-2323","doi":"https://doi.org/10.33380/2305-2066-2026-15-3-2323","is_oa":true,"landing_page_url":"https://doi.org/10.33380/2305-2066-2026-15-3-2323","pdf_url":"https://www.pharmjournal.ru/jour/article/download/2446/1537","source":{"id":"https://openalex.org/S4210178334","display_name":"Drug development & registration","issn_l":"2305-2066","issn":["2305-2066","2658-5049"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug development & registration","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.33380/2305-2066-2026-15-3-2323","doi":"https://doi.org/10.33380/2305-2066-2026-15-3-2323","is_oa":true,"landing_page_url":"https://doi.org/10.33380/2305-2066-2026-15-3-2323","pdf_url":"https://www.pharmjournal.ru/jour/article/download/2446/1537","source":{"id":"https://openalex.org/S4210178334","display_name":"Drug development & registration","issn_l":"2305-2066","issn":["2305-2066","2658-5049"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug development & registration","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6735000014305115,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204239074.pdf","grobid_xml":"https://content.openalex.org/works/W7204239074.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1995287540","https://openalex.org/W1997975781","https://openalex.org/W2005659898","https://openalex.org/W2011814478","https://openalex.org/W2090436419","https://openalex.org/W2514177463","https://openalex.org/W2797689099","https://openalex.org/W2891958316","https://openalex.org/W3012896294","https://openalex.org/W3014028256","https://openalex.org/W3118638666","https://openalex.org/W4210600296","https://openalex.org/W4386704257","https://openalex.org/W4391315491","https://openalex.org/W4413959748","https://openalex.org/W4416459485"],"related_works":["https://openalex.org/W2051679837","https://openalex.org/W2336728060","https://openalex.org/W2942058083","https://openalex.org/W2765665224","https://openalex.org/W2245834988","https://openalex.org/W2340768777","https://openalex.org/W3206546340","https://openalex.org/W2950130249"],"abstract_inverted_index":{"Introduction.":[0],"Amino":[1],"acids":[2,57],"(AAs)":[3],"are":[4,12],"key":[5],"components":[6],"of":[7,15,21,34,52,79,91,96,137,157,164,197,210,229,241,275,284,331],"living":[8],"organisms.":[9],"Medicinal":[10],"plants":[11],"valuable":[13],"sources":[14],"AAs,":[16,297],"which":[17,299],"enhance":[18],"the":[19,30,47,65,77,83,89,92,132,138,236,273,287,290,300,345],"bioavailability":[20],"other":[22],"metabolites":[23],"and":[24,49,54,69,161,166,188,192,225,239,256,319,328,333],"potentiate":[25],"their":[26],"pharmacological":[27],"effects.":[28],"However,":[29],"amino":[31,56,350],"acid":[32,114,351],"composition":[33,51,228,330],"many":[35],"plants,":[36],"including":[37],"Oxytropis":[38],"pilosa":[39,60,72,243,277,338],"(L.)":[40],"DC.,":[41],"remains":[42],"unexplored.":[43],"Aim.":[44],"To":[45],"establish":[46],"qualitative":[48,327],"quantitative":[50,162,329],"free":[53,97,140,165,230,267,332],"bound":[55,167,334],"in":[58,64,82,129,208,232,260,272,286,336],"O.":[59,71,242,276,337],"raw":[61,73,212,339],"material":[62,74,340],"growing":[63],"Saratov":[66,84],"region.":[67],"Materials":[68],"methods.":[70],"collected":[75],"during":[76],"period":[78],"mass":[80],"flowering":[81],"region":[85],"was":[86,99,142,169,206,244,270,353],"used":[87,200],"as":[88,131],"object":[90],"study.":[93],"Qualitative":[94,160],"analysis":[95,163,283],"AAs":[98,141,168,198,231,249,285,335,360],"performed":[100,170],"by":[101,145,171,246],"thin-layer":[102],"chromatography":[103],"(TLC)":[104],"using":[105,147,220],"an":[106,154,181,185],"n":[107],"-butanol":[108],"\u2013":[109,111,115],"acetone":[110],"glacial":[112],"acetic":[113],"water":[116],"system":[117],"(35":[118],":":[119,121,123],"35":[120],"10":[122],"20)":[124],"with":[125,180,358],"2":[126],"%":[127],"ninhydrin":[128],"alcohol":[130],"detection":[133],"reagent.":[134],"Quantitative":[135],"determination":[136],"total":[139,266,349],"carried":[143],"out":[144],"spectrophotometry":[146],"a":[148,174],"Shimadzu":[149,175],"UV-1800":[150],"spectrophotometer":[151],"(Japan)":[152],"at":[153],"analytical":[155],"wavelength":[156],"568":[158],"nm.":[159],"HPLC":[172,282],"on":[173],"LC-20":[176],"Prominence":[177],"chromatograph":[178],"equipped":[179],"SPD-M20A":[182],"detector":[183],"(Japan),":[184],"SIL-20A":[186],"autosampler,":[187],"LabSolutions":[189],"data":[190,216],"acquisition":[191],"processing":[193],"software.":[194],"Reference":[195],"standards":[196],"were":[199,217,258,303],"for":[201,344,362],"compound":[202],"identification.":[203],"AA":[204,268],"content":[205,269,352],"expressed":[207],"mg/g":[209],"dry":[211],"material.":[213],"The":[214,227,264,326,348],"obtained":[215],"statistically":[218],"processed":[219],"MS":[221],"Excel":[222],"2017.":[223],"Results":[224],"discussion.":[226],"aqueous":[233],"extracts":[234],"from":[235,289],"herb,":[237],"flowers,":[238],"leaves":[240],"determined":[245],"TLC.":[247],"Six":[248],"(aspartic":[250],"acid,":[251],"proline,":[252],"serine,":[253],"threonine,":[254],"valine,":[255],"isoleucine)":[257],"identified":[259],"all":[261],"studied":[262],"samples.":[263],"highest":[265],"found":[271],"herb":[274,291],"(30.70":[278],"\u00b1":[279,306,311,316,322,355,364],"0.39":[280],"mg/g).":[281,324],"extract":[288],"after":[292],"preliminary":[293],"hydrolysis":[294],"revealed":[295],"15":[296],"among":[298],"predominant":[301],"ones":[302],"alanine":[304],"(66.056":[305],"0.584":[307],"mg/g),":[308,313,318],"4-hydroxyproline":[309],"(25.912":[310],"0.278":[312],"proline":[314],"(17.834":[315],"0.168":[317],"histidine":[320],"(13.030":[321],"0.086":[323],"Conclusion.":[325],"has":[341],"been":[342],"established":[343],"first":[346],"time.":[347],"165.659":[354],"0.806":[356],"mg/g,":[357],"essential":[359],"accounting":[361],"16.958":[363],"0.139":[365],"mg/g.":[366]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2026-08-27T00:00:00"}