{"id":"https://openalex.org/W7204236451","doi":"https://doi.org/10.1097/icb.0000000000001844","title":"EXPLORING NOVEL APPLICATIONS OF RETROMODE IMAGING IN ANGIOID STREAKS","display_name":"EXPLORING NOVEL APPLICATIONS OF RETROMODE IMAGING IN ANGIOID STREAKS","publication_year":2026,"publication_date":"2026-08-26","ids":{"openalex":"https://openalex.org/W7204236451","doi":"https://doi.org/10.1097/icb.0000000000001844","pmid":"https://pubmed.ncbi.nlm.nih.gov/42647179"},"language":"en","primary_location":{"id":"doi:10.1097/icb.0000000000001844","doi":"https://doi.org/10.1097/icb.0000000000001844","is_oa":false,"landing_page_url":"https://doi.org/10.1097/icb.0000000000001844","pdf_url":null,"source":{"id":"https://openalex.org/S15540642","display_name":"Retinal Cases & Brief Reports","issn_l":"1935-1089","issn":["1935-1089","1937-1578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","medline"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RETINAL Cases & Brief Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035064730","display_name":"Claudio Xompero","orcid":"https://orcid.org/0009-0009-5082-0908","observed_orcids":["https://orcid.org/0009-0009-5082-0908"]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"id":"https://openalex.org/I4210159273","display_name":"H\u00f4pital Intercommunal de Cr\u00e9teil","ror":"https://ror.org/04n1nkp35","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210159273"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["FR","IT"],"is_corresponding":false,"raw_author_name":"Claudio Xompero","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Dentistry Sciences, Eye Clinic, University of Naples Federico II, Naples, Italy; and","Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Dentistry Sciences, Eye Clinic, University of Naples Federico II, Naples, Italy; and","institution_ids":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]},{"raw_affiliation_string":"Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;","institution_ids":["https://openalex.org/I4210159273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148261468","display_name":"Piera Giordano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Piera Giordano","raw_affiliation_strings":["Multidisciplinary Department of Medical, Surgical and Dental Sciences, Eye Clinic, Second University of Naples, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Multidisciplinary Department of Medical, Surgical and Dental Sciences, Eye Clinic, Second University of Naples, Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005554223","display_name":"Hoang Mai Le","orcid":"https://orcid.org/0009-0003-2433-8647","observed_orcids":["https://orcid.org/0009-0003-2433-8647"]},"institutions":[{"id":"https://openalex.org/I4210159273","display_name":"H\u00f4pital Intercommunal de Cr\u00e9teil","ror":"https://ror.org/04n1nkp35","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210159273"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Hoang Mai Le","raw_affiliation_strings":["Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;","institution_ids":["https://openalex.org/I4210159273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060337328","display_name":"Francesca Amoroso","orcid":"https://orcid.org/0000-0002-1435-389X","observed_orcids":["https://orcid.org/0000-0002-1435-389X"]},"institutions":[{"id":"https://openalex.org/I4210159273","display_name":"H\u00f4pital Intercommunal de Cr\u00e9teil","ror":"https://ror.org/04n1nkp35","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210159273"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Francesca Amoroso","raw_affiliation_strings":["Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;","institution_ids":["https://openalex.org/I4210159273"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086662698","display_name":"Eric H. Souied","orcid":"https://orcid.org/0000-0001-9388-202X","observed_orcids":["https://orcid.org/0000-0001-9388-202X"]},"institutions":[{"id":"https://openalex.org/I4210159273","display_name":"H\u00f4pital Intercommunal de Cr\u00e9teil","ror":"https://ror.org/04n1nkp35","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210159273"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Eric H. Souied","raw_affiliation_strings":["Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, H\u00f4pital Intercommunal de Creteil, Cr\u00e9teil, France;","institution_ids":["https://openalex.org/I4210159273"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.77263041,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":"5","first_page":"691","last_page":"694"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.13439999520778656,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/angioid-streaks","display_name":"angioid streaks","score":0.9890000224113464},{"id":"https://openalex.org/keywords/retinal-pigment-epithelium","display_name":"retinal pigment epithelium","score":0.9490000009536743},{"id":"https://openalex.org/keywords/bruch-s-membrane","display_name":"Bruch's membrane","score":0.9520000219345093},{"id":"https://openalex.org/keywords/fundus-autofluorescence","display_name":"fundus autofluorescence","score":0.7310000061988831},{"id":"https://openalex.org/keywords/spectral-domain-optical-coherence-tomography","display_name":"spectral-domain optical coherence tomography","score":0.9789999723434448},{"id":"https://openalex.org/keywords/choroidal-neovascularization","display_name":"choroidal neovascularization","score":0.828000009059906},{"id":"https://openalex.org/keywords/retinal-imaging","display_name":"retinal imaging","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.8508999943733215},{"id":"https://openalex.org/C2778784831","wikidata":"https://www.wikidata.org/wiki/Q4763261","display_name":"Angioid streaks","level":4,"score":0.6880999803543091},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6615999937057495},{"id":"https://openalex.org/C2777474606","wikidata":"https://www.wikidata.org/wiki/Q7430070","display_name":"Scanning laser ophthalmoscopy","level":3,"score":0.6599000096321106},{"id":"https://openalex.org/C2780623050","wikidata":"https://www.wikidata.org/wiki/Q837188","display_name":"Ophthalmoscopy","level":3,"score":0.5720000267028809},{"id":"https://openalex.org/C179687394","wikidata":"https://www.wikidata.org/wiki/Q4826281","display_name":"Autofluorescence","level":3,"score":0.48559999465942383},{"id":"https://openalex.org/C2778024200","wikidata":"https://www.wikidata.org/wiki/Q2346242","display_name":"Retinal pigment epithelium","level":3,"score":0.4659000039100647},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.4408999979496002},{"id":"https://openalex.org/C2776391266","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Fundus (uterus)","level":2,"score":0.41519999504089355},{"id":"https://openalex.org/C2776474195","wikidata":"https://www.wikidata.org/wiki/Q1144413","display_name":"Fundus photography","level":4,"score":0.3555000126361847},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.3422999978065491},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.34150001406669617},{"id":"https://openalex.org/C65185188","wikidata":"https://www.wikidata.org/wiki/Q107775","display_name":"Streak","level":2,"score":0.32510000467300415},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.3228999972343445},{"id":"https://openalex.org/C2781359195","wikidata":"https://www.wikidata.org/wiki/Q5105209","display_name":"Choroidal neovascularization","level":3,"score":0.29919999837875366},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.29249998927116394},{"id":"https://openalex.org/C2780248432","wikidata":"https://www.wikidata.org/wiki/Q1434206","display_name":"Fluorescein angiography","level":3,"score":0.2879999876022339},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.2831000089645386},{"id":"https://openalex.org/C2776694393","wikidata":"https://www.wikidata.org/wiki/Q271762","display_name":"Choroid","level":3,"score":0.2728999853134155}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000793","descriptor_name":"Angioid Streaks","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000793","descriptor_name":"Angioid Streaks","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005451","descriptor_name":"Fluorescein Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005654","descriptor_name":"Fundus Oculi","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009887","descriptor_name":"Ophthalmoscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055213","descriptor_name":"Retinal Pigment Epithelium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/icb.0000000000001844","doi":"https://doi.org/10.1097/icb.0000000000001844","is_oa":false,"landing_page_url":"https://doi.org/10.1097/icb.0000000000001844","pdf_url":null,"source":{"id":"https://openalex.org/S15540642","display_name":"Retinal Cases & Brief Reports","issn_l":"1935-1089","issn":["1935-1089","1937-1578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","medline"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RETINAL Cases & Brief Reports","raw_type":"journal-article"},{"id":"pmid:42647179","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42647179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retinal cases & brief reports","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7246000170707703,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W2041553293","https://openalex.org/W2147909867","https://openalex.org/W2153740155","https://openalex.org/W2563251207","https://openalex.org/W2893405599","https://openalex.org/W2893829828","https://openalex.org/W4386532497","https://openalex.org/W4391849242","https://openalex.org/W4404678099"],"related_works":[],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"evaluate":[2],"retromode":[3],"scanning":[4,57,147],"laser":[5,58,148],"ophthalmoscopy":[6,59,149],"(RM-SLO)":[7],"for":[8,183],"detecting":[9],"and":[10,35,41,66,78,97,128,158,163,175],"characterizing":[11],"angioid":[12],"streaks":[13],"(AS).":[14],"METHODS:":[15],"Retrospective":[16],"case":[17],"series":[18,179],"of":[19,80,161],"five":[20],"patients":[21],"(10":[22],"eyes)":[23],"imaged":[24],"with":[25,125],"color":[26,104],"fundus,":[27],"fundus":[28],"autofluorescence,":[29],"spectral-domain":[30],"optical":[31,117],"coherence":[32,118,168],"tomography":[33,119,169],"(OCT),":[34],"RM-SLO":[36],"using":[37],"right-deviated,":[38],"left-deviated":[39],"(DL),":[40],"ring/central":[42],"apertures.":[43],"Two":[44],"graders":[45],"assessed":[46],"images;":[47],"disagreements":[48],"were":[49],"adjudicated":[50],"by":[51,154],"a":[52],"third":[53],"expert.":[54],"RESULTS:":[55],"Retromode":[56,146],"depicted":[60],"AS":[61,162],"as":[62],"hyporeflective":[63],"bands.":[64],"Right-deviated":[65],"DL":[67],"produced":[68],"polarity-dependent,":[69],"relief-like":[70],"pseudo-3D":[71],"cues":[72],"attributable":[73],"to":[74],"lateral":[75],"aperture":[76],"deviation":[77],"collection":[79],"multiply":[81],"scattered":[82],"infrared":[83],"light":[84],"at":[85,139],"the":[86,172],"retinal":[87],"pigment":[88],"epithelium":[89],"(RPE)/Bruch":[90],"membrane":[91],"interface.":[92],"Ring/central":[93],"maximized":[94],"border":[95,156],"sharpness":[96],"preserved":[98],"apparent":[99],"streak":[100],"width,":[101],"closely":[102],"matching":[103],"images.":[105],"Fundus":[106],"autofluorescence":[107],"confirmed":[108],"hypoautofluorescent":[109],"bands":[110],"but":[111],"provided":[112],"less":[113],"edge":[114],"detail.":[115],"Spectral-domain":[116],"(SD-OCT)":[120],"corroborated":[121],"RPE/Bruch":[122],"complex":[123],"abnormalities":[124],"focal":[126],"discontinuities":[127],"localized":[129],"hypertransmission.":[130],"In":[131],"this":[132,178],"cohort,":[133],"no":[134],"choroidal":[135],"neovascularization":[136],"was":[137,180],"present":[138],"imaging":[140],"or":[141],"during":[142],"documented":[143],"follow-up.":[144],"CONCLUSION:":[145],"complements":[150],"conventional":[151],"en-face":[152],"modalities":[153],"enhancing":[155],"delineation":[157],"rapid":[159],"mapping":[160],"can":[164],"guide":[165],"targeted":[166],"OCT/optical":[167],"angiography.":[170],"Given":[171],"small":[173],"sample":[174],"retrospective":[176],"design,":[177],"not":[181],"powered":[182],"head-to-head":[184],"detection-rate":[185],"comparisons;":[186],"prospective":[187],"studies":[188],"are":[189],"warranted.":[190]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-08-27T00:00:00"}