{"id":"https://openalex.org/W7204227456","doi":"https://doi.org/10.1167/iovs.67.10.62","title":"Morphometric Analysis of Retinal Vessels Using High-Resolution OCT Technology in Healthy Subjects","display_name":"Morphometric Analysis of Retinal Vessels Using High-Resolution OCT Technology in Healthy Subjects","publication_year":2026,"publication_date":"2026-08-26","ids":{"openalex":"https://openalex.org/W7204227456","doi":"https://doi.org/10.1167/iovs.67.10.62","pmid":"https://pubmed.ncbi.nlm.nih.gov/42644677"},"language":"en","primary_location":{"id":"doi:10.1167/iovs.67.10.62","doi":"https://doi.org/10.1167/iovs.67.10.62","is_oa":true,"landing_page_url":"https://doi.org/10.1167/iovs.67.10.62","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-2","ki-jl-2","medline","norway-2"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative Ophthalmology &amp; Visual Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1167/iovs.67.10.62","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025428879","display_name":"Mariano Cozzi","orcid":"https://orcid.org/0000-0001-7777-2461","observed_orcids":["https://orcid.org/0000-0001-7777-2461"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I4210087773","display_name":"Luigi Sacco Hospital","ror":"https://ror.org/0025g8755","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210087773","https://openalex.org/I4210156709"]},{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH","IT"],"is_corresponding":false,"raw_author_name":"Mariano Cozzi","raw_affiliation_strings":["Department of Ophthalmology, University Hospital Zurich and University of Zurich, Zurich, Switzerland","Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, University Hospital Zurich and University of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423","https://openalex.org/I4210100468"]},{"raw_affiliation_string":"Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210087773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111897605","display_name":"Valeria Motta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210087773","display_name":"Luigi Sacco Hospital","ror":"https://ror.org/0025g8755","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210087773","https://openalex.org/I4210156709"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Valeria Motta","raw_affiliation_strings":["Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210087773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148390756","display_name":"Alida Longoni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210087773","display_name":"Luigi Sacco Hospital","ror":"https://ror.org/0025g8755","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210087773","https://openalex.org/I4210156709"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alida Longoni","raw_affiliation_strings":["Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210087773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092502696","display_name":"Andrea Trinco","orcid":"https://orcid.org/0009-0007-7328-1519","observed_orcids":["https://orcid.org/0009-0007-7328-1519"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210087773","display_name":"Luigi Sacco Hospital","ror":"https://ror.org/0025g8755","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210087773","https://openalex.org/I4210156709"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Trinco","raw_affiliation_strings":["Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210087773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076161106","display_name":"Giovanni Staurenghi","orcid":"https://orcid.org/0000-0002-2299-5251","observed_orcids":["https://orcid.org/0000-0002-2299-5251"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210087773","display_name":"Luigi Sacco Hospital","ror":"https://ror.org/0025g8755","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210087773","https://openalex.org/I4210156709"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Staurenghi","raw_affiliation_strings":["Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210087773"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013143889","display_name":"Alessandro Invernizzi","orcid":"https://orcid.org/0000-0003-3400-1987","observed_orcids":["https://orcid.org/0000-0003-3400-1987"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210087773","display_name":"Luigi Sacco Hospital","ror":"https://ror.org/0025g8755","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210087773","https://openalex.org/I4210156709"]}],"countries":["AU","IT"],"is_corresponding":true,"raw_author_name":"Alessandro Invernizzi","raw_affiliation_strings":["Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy","The University of Sydney, Save Sight Institute, Discipline of Ophthalmology, Sydney Medical School, Sydney, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210087773"]},{"raw_affiliation_string":"The University of Sydney, Save Sight Institute, Discipline of Ophthalmology, Sydney Medical School, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5013143889"],"corresponding_institution_ids":["https://openalex.org/I129604602","https://openalex.org/I189158943","https://openalex.org/I4210087773"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.59488785,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"67","issue":"10","first_page":"62","last_page":"62"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.6151999831199646,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.6151999831199646,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.3596000075340271,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-vessels","display_name":"retinal vasculature","score":0.7649999856948853},{"id":"https://openalex.org/keywords/high-resolution-optical-coherence-tomography","display_name":"high-resolution optical coherence tomography","score":0.9599999785423279},{"id":"https://openalex.org/keywords/retinal-vessel-diameter","display_name":"retinal vessel diameter","score":0.7490000128746033},{"id":"https://openalex.org/keywords/arterial-wall-thickness","display_name":"arterial wall thickness","score":0.6389999985694885},{"id":"https://openalex.org/keywords/inter-device-agreement","display_name":"inter-device agreement","score":0.6349999904632568},{"id":"https://openalex.org/keywords/age-related-changes","display_name":"age-related changes","score":0.5070000290870667},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8759999871253967},{"id":"https://openalex.org/keywords/healthy-volunteers","display_name":"healthy volunteers","score":0.5699999928474426},{"id":"https://openalex.org/keywords/noninvasive-vascular-imaging","display_name":"noninvasive vascular imaging","score":0.8659999966621399}],"concepts":[{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.8130000233650208},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8043000102043152},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6848999857902527},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5181000232696533},{"id":"https://openalex.org/C9893847","wikidata":"https://www.wikidata.org/wiki/Q1425625","display_name":"Reproducibility","level":2,"score":0.44339999556541443},{"id":"https://openalex.org/C40993552","wikidata":"https://www.wikidata.org/wiki/Q514654","display_name":"Gold standard (test)","level":2,"score":0.37880000472068787},{"id":"https://openalex.org/C3020090656","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Arterial wall","level":2,"score":0.3416000008583069},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3357999920845032},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.30790001153945923},{"id":"https://openalex.org/C3020199158","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"High resolution","level":2,"score":0.29420000314712524},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2808000147342682},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.2655999958515167},{"id":"https://openalex.org/C2777663904","wikidata":"https://www.wikidata.org/wiki/Q988343","display_name":"Blood vessel","level":2,"score":0.265500009059906},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.2651999890804291}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1167/iovs.67.10.62","doi":"https://doi.org/10.1167/iovs.67.10.62","is_oa":true,"landing_page_url":"https://doi.org/10.1167/iovs.67.10.62","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-2","ki-jl-2","medline","norway-2"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative Ophthalmology &amp; Visual Science","raw_type":"journal-article"},{"id":"pmid:42644677","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42644677","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13533305","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13533305/pdf/iovs-67-10-62.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Invest Ophthalmol Vis Sci","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1167/iovs.67.10.62","doi":"https://doi.org/10.1167/iovs.67.10.62","is_oa":true,"landing_page_url":"https://doi.org/10.1167/iovs.67.10.62","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-2","ki-jl-2","medline","norway-2"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative Ophthalmology &amp; Visual Science","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1542177775","https://openalex.org/W1978174623","https://openalex.org/W1992073218","https://openalex.org/W2010908943","https://openalex.org/W2027432853","https://openalex.org/W2066952003","https://openalex.org/W2075606314","https://openalex.org/W2076733352","https://openalex.org/W2078239496","https://openalex.org/W2079908968","https://openalex.org/W2116201282","https://openalex.org/W2132636854","https://openalex.org/W2137015106","https://openalex.org/W2141460031","https://openalex.org/W2474279305","https://openalex.org/W2765249000","https://openalex.org/W2908380584","https://openalex.org/W3031363739","https://openalex.org/W3036733277","https://openalex.org/W3087147729","https://openalex.org/W3121750693","https://openalex.org/W3181524961","https://openalex.org/W3198873022","https://openalex.org/W3202042470","https://openalex.org/W3203535471","https://openalex.org/W4210348187","https://openalex.org/W4248116761","https://openalex.org/W4281879014","https://openalex.org/W4283456219","https://openalex.org/W4321337843","https://openalex.org/W4383710413","https://openalex.org/W4388077475","https://openalex.org/W4407398004"],"related_works":[],"abstract_inverted_index":{"Purpose:":[0],"To":[1],"assess":[2,57],"the":[3,76,148,176],"performance":[4],"of":[5,225],"a":[6],"novel":[7],"high-resolution":[8],"optical":[9],"coherence":[10],"tomography":[11],"(High-Res":[12],"OCT)":[13],"research":[14],"platform":[15],"with":[16,32,50,71,111,201],"3-\u00b5m":[17],"axial":[18],"resolution":[19],"in":[20,25,179,193,211,241],"measuring":[21],"retinal":[22,226],"vascular":[23,80,227,243],"metrics":[24,82,229],"healthy":[26,119],"subjects,":[27],"and":[28,53,59,83,90,94,137,150,182,198,223,245],"to":[29,56,74,108,139,163,231],"compare":[30],"it":[31],"standard":[33,52,142,164,232],"OCT.":[34,233],"Methods:":[35],"This":[36],"observational,":[37],"cross-sectional":[38],"study":[39],"comprised":[40],"two":[41,177],"phases.":[42],"In":[43,62],"Phase":[44,63],"I,":[45],"36":[46],"eyes":[47,116],"underwent":[48],"imaging":[49,244],"both":[51,180],"High-Res":[54,72,129,160,219],"OCT":[55,73,101,130,143,161,165,220],"inter-device":[58],"inter-grader":[60],"agreement.":[61],"II,":[64],"an":[65],"expanded":[66],"cohort":[67],"was":[68,126,173,190],"imaged":[69],"exclusively":[70],"investigate":[75],"possible":[77],"associations":[78,110],"between":[79],"wall":[81,92,152,213,228],"systemic":[84,246],"factors.":[85],"Vascular":[86],"measurements":[87],"included":[88],"anterior":[89],"posterior":[91],"thickness":[93,153,189,214],"vessel":[95,171],"diameter,":[96],"manually":[97],"assessed":[98],"using":[99],"standardized":[100],"protocols.":[102],"Linear":[103],"mixed-effects":[104],"models":[105],"were":[106,121,154,209],"used":[107],"evaluate":[109],"clinical":[112],"variables.":[113],"Results:":[114],"Eighty-seven":[115],"from":[117],"44":[118],"subjects":[120],"overall":[122],"included.":[123],"Inter-grader":[124],"agreement":[125],"excellent":[127],"for":[128,141],"(intraclass":[131],"correlation":[132],"coefficient":[133],"[ICC]":[134],"range":[135,145],"0.94-0.96)":[136],"good":[138],"excellence":[140],"(ICC":[144],"0.83-0.88).":[146],"Both":[147],"arterial":[149],"venous":[151,212],"significantly":[155,191],"thinner":[156],"when":[157],"measured":[158],"by":[159],"compared":[162,230],"(P":[166,184,195,203,215],"<":[167,204],"0.001).":[168,205],"The":[169],"entire":[170],"diameter":[172],"similar":[174],"across":[175],"techniques":[178],"arteries":[181],"veins":[183],">":[185],"0.05).":[186],"Arterial":[187],"walls":[188],"greater":[192],"males":[194],"=":[196,216],"0.033)":[197],"positively":[199],"associated":[200],"age":[202],"Similar":[206],"age-related":[207],"trends":[208],"observed":[210],"0.006).":[217],"Conclusions:":[218],"improved":[221],"visualization":[222],"reproducibility":[224],"These":[234],"findings":[235],"suggest":[236],"its":[237],"future":[238],"potential":[239],"role":[240],"noninvasive":[242],"health":[247],"assessment.":[248]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2026-08-27T00:00:00"}