{"id":"https://openalex.org/W7204180647","doi":"https://doi.org/10.1186/s13071-026-07624-6","title":"Decoding the sand fly\u2013Leishmania interaction: from biological insights to disease control","display_name":"Decoding the sand fly\u2013Leishmania interaction: from biological insights to disease control","publication_year":2026,"publication_date":"2026-08-26","ids":{"openalex":"https://openalex.org/W7204180647","doi":"https://doi.org/10.1186/s13071-026-07624-6"},"language":"en","primary_location":{"id":"doi:10.1186/s13071-026-07624-6","doi":"https://doi.org/10.1186/s13071-026-07624-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13071-026-07624-6","pdf_url":null,"source":{"id":"https://openalex.org/S80413395","display_name":"Parasites & Vectors","issn_l":"1756-3305","issn":["1756-3305"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasites & Vectors","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s13071-026-07624-6","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022409737","display_name":"Erich Loza Telleria","orcid":"https://orcid.org/0000-0003-0006-0057","observed_orcids":["https://orcid.org/0000-0003-0006-0057"]},"institutions":[{"id":"https://openalex.org/I21250087","display_name":"Charles University","ror":"https://ror.org/024d6js02","country_code":"CZ","type":"education","lineage":["https://openalex.org/I21250087"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Erich Loza Telleria","raw_affiliation_strings":["Department of Parasitology, Faculty of Science, Charles University, Prague, Czechia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Faculty of Science, Charles University, Prague, Czechia","institution_ids":["https://openalex.org/I21250087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042261215","display_name":"Vinicius Wakoff Pereira Fonseca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Vinicius Wakoff Fonseca","raw_affiliation_strings":["Laborat\u00f3rio de Biologia Molecular de Parasitos e Vetores - IOC Fiocruz, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Biologia Molecular de Parasitos e Vetores - IOC Fiocruz, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040771785","display_name":"Antonio Jorge Tempone","orcid":"https://orcid.org/0000-0003-2974-4532","observed_orcids":["https://orcid.org/0000-0003-2974-4532"]},"institutions":[{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Antonio Jorge Tempone","raw_affiliation_strings":["Laborat\u00f3rio de Biologia Molecular de Parasitos e Vetores - IOC Fiocruz, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Biologia Molecular de Parasitos e Vetores - IOC Fiocruz, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I52325"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038254046","display_name":"Yara Maria Traub-Csek\u00f6","orcid":"https://orcid.org/0000-0002-9676-3381","observed_orcids":["https://orcid.org/0000-0002-9676-3381"]},"institutions":[{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Yara Maria Traub-Cseko","raw_affiliation_strings":["Laborat\u00f3rio de Biologia Molecular de Parasitos e Vetores - IOC Fiocruz, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Biologia Molecular de Parasitos e Vetores - IOC Fiocruz, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I52325"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5038254046"],"corresponding_institution_ids":["https://openalex.org/I52325"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.67948552,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leishmania","display_name":"Leishmania","score":0.8009999990463257},{"id":"https://openalex.org/keywords/sand-fly-vectors","display_name":"sand fly vectors","score":0.6949999928474426},{"id":"https://openalex.org/keywords/vector-competence","display_name":"vector competence","score":0.7850000262260437},{"id":"https://openalex.org/keywords/parasite-vector-interactions","display_name":"vector-parasite interactions","score":0.6600000262260437},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7799999713897705},{"id":"https://openalex.org/keywords/innate-immune-signaling","display_name":"innate immune signaling","score":0.8159999847412109},{"id":"https://openalex.org/keywords/symbiotic-bacteria","display_name":"symbiotic bacteria","score":0.9259999990463257},{"id":"https://openalex.org/keywords/antiviral-defense","display_name":"antiviral defense","score":0.7179999947547913},{"id":"https://openalex.org/keywords/virulence-strategies","display_name":"virulence strategies","score":0.7599999904632568},{"id":"https://openalex.org/keywords/transmission-blocking","display_name":"transmission blocking","score":0.6010000109672546},{"id":"https://openalex.org/keywords/vector-borne-disease-transmission","display_name":"vector-borne transmission","score":0.6919999718666077}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6492999792098999},{"id":"https://openalex.org/C57273362","wikidata":"https://www.wikidata.org/wiki/Q576722","display_name":"Decoding methods","level":2,"score":0.5849000215530396},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.42640000581741333},{"id":"https://openalex.org/C147135968","wikidata":"https://www.wikidata.org/wiki/Q39286","display_name":"Entomology","level":2,"score":0.42080000042915344},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39160001277923584},{"id":"https://openalex.org/C190612196","wikidata":"https://www.wikidata.org/wiki/Q180502","display_name":"Parasitology","level":2,"score":0.38100001215934753},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.3808000087738037},{"id":"https://openalex.org/C2991849723","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Molecular cell biology","level":2,"score":0.3783000111579895},{"id":"https://openalex.org/C2987315675","wikidata":"https://www.wikidata.org/wiki/Q1773974","display_name":"Disease control","level":2,"score":0.36500000953674316},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.29280000925064087},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2603999972343445},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.25679999589920044},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.2513999938964844}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s13071-026-07624-6","doi":"https://doi.org/10.1186/s13071-026-07624-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13071-026-07624-6","pdf_url":null,"source":{"id":"https://openalex.org/S80413395","display_name":"Parasites & Vectors","issn_l":"1756-3305","issn":["1756-3305"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasites & Vectors","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s13071-026-07624-6","doi":"https://doi.org/10.1186/s13071-026-07624-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13071-026-07624-6","pdf_url":null,"source":{"id":"https://openalex.org/S80413395","display_name":"Parasites & Vectors","issn_l":"1756-3305","issn":["1756-3305"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasites & Vectors","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Leishmaniasis":[0],"persists":[1],"as":[2],"a":[3,11,71],"major":[4],"yet":[5],"under-controlled":[6],"vector-borne":[7],"disease,":[8],"maintained":[9],"by":[10,60],"highly":[12],"specialized":[13],"and":[14,20,36,66,80,99,107,126],"dynamic":[15],"interaction":[16],"between":[17],"Leishmania":[18,88],"parasites":[19],"their":[21],"sand":[22,75],"fly":[23,76],"vectors.":[24],"Understanding":[25],"how":[26,121],"vector":[27,101],"competence":[28],"emerges":[29],"from":[30,151],"the":[31,74,81],"integration":[32],"of":[33,135],"molecular,":[34],"immunological,":[35],"microbiome-driven":[37],"processes":[38],"is":[39],"critical":[40],"for":[41,148],"identifying":[42],"novel":[43],"intervention":[44],"points":[45],"to":[46,103,154],"reduce":[47],"disease":[48,160],"incidence.":[49],"We":[50,118,143],"share":[51],"our":[52],"perspective":[53],"on":[54,112],"this":[55],"multilayered":[56],"biological":[57],"dialogue":[58],"shaped":[59],"molecular":[61],"interactions,":[62],"innate":[63],"immune":[64,97],"signaling,":[65],"microbiota":[67],"ecology.":[68],"Rather":[69],"than":[70],"non-reactive":[72],"host,":[73],"regulates":[77],"digestion,":[78],"immunity,":[79],"resident":[82],"microbial":[83],"gut":[84,95],"communities.":[85],"In":[86],"parallel,":[87],"deploys":[89],"virulence":[90],"strategies":[91],"that":[92,137,157],"can":[93,158],"manipulate":[94],"physiology,":[96],"responses,":[98],"even":[100],"behavior":[102],"ensure":[104],"its":[105,163],"survival":[106],"transmission.":[108],"The":[109],"outcomes":[110],"depend":[111],"timing":[113],"and,":[114],"eventually,":[115],"species-specific":[116],"compatibility.":[117],"further":[119],"explore":[120],"antiviral":[122],"defenses,":[123],"bacterial":[124],"symbionts,":[125],"metabolic":[127],"context":[128],"intersect":[129],"with":[130],"parasite":[131],"development,":[132],"revealing":[133],"layers":[134],"complexity":[136],"extend":[138],"beyond":[139],"basic":[140],"parasite\u2013vector":[141],"models.":[142],"point":[144],"out":[145],"new":[146],"opportunities":[147],"intervention,":[149],"ranging":[150],"transmission-blocking":[152],"approaches":[153],"microbiome-based":[155],"control":[156],"disrupt":[159],"transmission":[161],"at":[162],"source.":[164]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-08-26T00:00:00"}