{"id":"https://openalex.org/W7204180235","doi":"https://doi.org/10.1056/evidmr2500143","title":"A 6-Month-Old Infant with Episodes of Unresponsiveness","display_name":"A 6-Month-Old Infant with Episodes of Unresponsiveness","publication_year":2026,"publication_date":"2026-08-25","ids":{"openalex":"https://openalex.org/W7204180235","doi":"https://doi.org/10.1056/evidmr2500143","pmid":"https://pubmed.ncbi.nlm.nih.gov/42640167"},"language":"en","primary_location":{"id":"doi:10.1056/evidmr2500143","doi":"https://doi.org/10.1056/evidmr2500143","is_oa":false,"landing_page_url":"https://doi.org/10.1056/evidmr2500143","pdf_url":null,"source":{"id":"https://openalex.org/S4210196357","display_name":"NEJM Evidence","issn_l":"2766-5526","issn":["2766-5526"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NEJM Evidence","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018364219","display_name":"Khalifah A Aldawsari","orcid":"https://orcid.org/0000-0003-0163-8658","observed_orcids":["https://orcid.org/0000-0003-0163-8658"]},"institutions":[{"id":"https://openalex.org/I4210096275","display_name":"Children's Hospital Colorado","ror":"https://ror.org/00mj9k629","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210096275"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Khalifah A. Aldawsari","raw_affiliation_strings":["from the Pediatric Cardiology fellowship program at Children\u2019s Hospital Colorado, University of Colorado Anschutz Medical Campus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"from the Pediatric Cardiology fellowship program at Children\u2019s Hospital Colorado, University of Colorado Anschutz Medical Campus","institution_ids":["https://openalex.org/I4210096275","https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091535179","display_name":"Jane Nydam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096275","display_name":"Children's Hospital Colorado","ror":"https://ror.org/00mj9k629","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210096275"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane Nydam","raw_affiliation_strings":["from the Pediatric Cardiology fellowship program at Children\u2019s Hospital Colorado, University of Colorado Anschutz Medical Campus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"from the Pediatric Cardiology fellowship program at Children\u2019s Hospital Colorado, University of Colorado Anschutz Medical Campus","institution_ids":["https://openalex.org/I4210096275","https://openalex.org/I51713134"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088867670","display_name":"Kathryn C. Chatfield","orcid":"https://orcid.org/0000-0003-0021-1097","observed_orcids":["https://orcid.org/0000-0003-0021-1097"]},"institutions":[{"id":"https://openalex.org/I4210096275","display_name":"Children's Hospital Colorado","ror":"https://ror.org/00mj9k629","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210096275"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathryn C. Chatfield","raw_affiliation_strings":["from the Pediatric Cardiology fellowship program at Children\u2019s Hospital Colorado, University of Colorado Anschutz Medical Campus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"from the Pediatric Cardiology fellowship program at Children\u2019s Hospital Colorado, University of Colorado Anschutz Medical Campus","institution_ids":["https://openalex.org/I4210096275","https://openalex.org/I51713134"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.71690765,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"9","first_page":"EVIDmr2500143","last_page":"EVIDmr2500143"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13533","display_name":"Medical Case Reports and Studies","score":0.3628000020980835,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13533","display_name":"Medical Case Reports and Studies","score":0.3628000020980835,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.17739999294281006,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12845","display_name":"Methemoglobinemia and Tumor Lysis Syndrome","score":0.04470000043511391,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyanosis","display_name":"cyanosis","score":0.796999990940094},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.875},{"id":"https://openalex.org/keywords/physical-examination","display_name":"physical examination","score":0.414000004529953},{"id":"https://openalex.org/keywords/diagnostic-workup","display_name":"diagnostic workup","score":0.4169999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7202000021934509},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.649399995803833},{"id":"https://openalex.org/C2780801072","wikidata":"https://www.wikidata.org/wiki/Q837512","display_name":"Differential diagnosis","level":2,"score":0.5235999822616577},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5156999826431274},{"id":"https://openalex.org/C2780129039","wikidata":"https://www.wikidata.org/wiki/Q1931107","display_name":"Section (typography)","level":2,"score":0.4138999879360199},{"id":"https://openalex.org/C527108885","wikidata":"https://www.wikidata.org/wiki/Q835153","display_name":"Physical examination","level":2,"score":0.3416999876499176},{"id":"https://openalex.org/C3019796121","wikidata":"https://www.wikidata.org/wiki/Q5048356","display_name":"Case presentation","level":2,"score":0.31049999594688416},{"id":"https://openalex.org/C2983449737","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Clinical diagnosis","level":2,"score":0.28839999437332153},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.2734000086784363},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.27309998869895935},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.26010000705718994}],"mesh":[{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014474","descriptor_name":"Unconsciousness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1056/evidmr2500143","doi":"https://doi.org/10.1056/evidmr2500143","is_oa":false,"landing_page_url":"https://doi.org/10.1056/evidmr2500143","pdf_url":null,"source":{"id":"https://openalex.org/S4210196357","display_name":"NEJM Evidence","issn_l":"2766-5526","issn":["2766-5526"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NEJM Evidence","raw_type":"journal-article"},{"id":"pmid:42640167","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42640167","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NEJM evidence","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"sustainable_development_goals_aurora":[{"display_name":"Gender equality","id":"https://metadata.un.org/sdg/5","score":0.5412887334823608}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1923558412","https://openalex.org/W2068520976","https://openalex.org/W2136740180","https://openalex.org/W2171116570","https://openalex.org/W2553882831","https://openalex.org/W2751637236","https://openalex.org/W3038211111"],"related_works":[],"abstract_inverted_index":{"AbstractMorning":[0],"Report":[1,25],"is":[2,103,108],"a":[3,35,46,65,106],"time-honored":[4],"tradition":[5,32],"where":[6],"physicians-in-training":[7],"present":[8],"cases":[9],"to":[10,16,28,44],"their":[11],"colleagues":[12],"and":[13,39,49,77,87],"clinical":[14,98],"experts":[15],"collaboratively":[17],"examine":[18],"an":[19,89],"interesting":[20],"patient":[21],"presentation.":[22],"The":[23],"Morning":[24],"section":[26],"seeks":[27],"carry":[29],"on":[30],"this":[31],"by":[33],"presenting":[34],"patient's":[36],"chief":[37],"concern":[38],"story,":[40],"inviting":[41],"the":[42,51,54,57,62,81,93,97,101],"reader":[43],"develop":[45],"differential":[47,102],"diagnosis":[48,52,107],"discover":[50],"alongside":[53],"authors":[55],"of":[56,64,73,75,80],"case.":[58],"This":[59],"report":[60],"examines":[61],"story":[63],"6-month-old":[66],"male":[67],"infant":[68],"brought":[69],"in":[70],"for":[71,92],"evaluation":[72],"episodes":[74],"unresponsiveness":[76],"bluish":[78],"discoloration":[79],"lips.":[82],"Using":[83],"questions,":[84],"physical":[85],"examination,":[86],"testing,":[88],"illness":[90],"script":[91],"presentation":[94],"emerges.":[95],"As":[96],"course":[99],"progresses,":[100],"refined":[104],"until":[105],"made.":[109]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-08-26T00:00:00"}