{"id":"https://openalex.org/W7204173620","doi":"https://doi.org/10.5281/zenodo.22099443","title":"Termal ve Ak\u0131\u015fkan Bilimleri A\u00e7\u0131s\u0131ndan Alzheimer Hastal\u0131\u011f\u0131n\u0131n Navier\u2013Stokes Denklemleri \u0130le Modellenmesi, Erken Te\u015fhis ve Tedavi Yakla\u015f\u0131mlar\u0131","display_name":"Termal ve Ak\u0131\u015fkan Bilimleri A\u00e7\u0131s\u0131ndan Alzheimer Hastal\u0131\u011f\u0131n\u0131n Navier\u2013Stokes Denklemleri \u0130le Modellenmesi, Erken Te\u015fhis ve Tedavi Yakla\u015f\u0131mlar\u0131","publication_year":2026,"publication_date":"2026-08-26","ids":{"openalex":"https://openalex.org/W7204173620","doi":"https://doi.org/10.5281/zenodo.22099443"},"language":"en","primary_location":{"id":"doi:10.5281/zenodo.22099443","doi":"https://doi.org/10.5281/zenodo.22099443","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22099443","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.22099443","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028045351","display_name":"Emin Taner ELMAS","orcid":"https://orcid.org/0000-0002-7290-2308","observed_orcids":["https://orcid.org/0000-0002-7290-2308"]},"institutions":[{"id":"https://openalex.org/I344703621","display_name":"I\u011fd\u0131r \u00dcniversitesi","ror":"https://ror.org/05jstgx72","country_code":"TR","type":"education","lineage":["https://openalex.org/I344703621"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Elmas, E. T.","raw_affiliation_strings":["Dr. \u00d6\u011fr. \u00dcyesi ve Makina Y\u00fcksek M\u00fchendisi; Motorlu Ara\u00e7lar ve Ula\u015ft\u0131rma Teknolojileri B\u00f6l\u00fcm\u00fc, Otomotiv Teknolojisi, Teknik Bilimler MYO, I\u011fd\u0131r \u00dcniversitesi, T\u00fcrkiye, Biyom\u00fchendislik ve Bilimleri Anabilim Dal\u0131, Lisans\u00fcst\u00fc E\u011fitim Enstit\u00fcs\u00fc, I\u011fd\u0131r \u00dcniversitesi, T\u00fcrkiye-76000"],"raw_orcid":"https://orcid.org/0000-0002-7290-2308","affiliations":[{"raw_affiliation_string":"Dr. \u00d6\u011fr. \u00dcyesi ve Makina Y\u00fcksek M\u00fchendisi; Motorlu Ara\u00e7lar ve Ula\u015ft\u0131rma Teknolojileri B\u00f6l\u00fcm\u00fc, Otomotiv Teknolojisi, Teknik Bilimler MYO, I\u011fd\u0131r \u00dcniversitesi, T\u00fcrkiye, Biyom\u00fchendislik ve Bilimleri Anabilim Dal\u0131, Lisans\u00fcst\u00fc E\u011fitim Enstit\u00fcs\u00fc, I\u011fd\u0131r \u00dcniversitesi, T\u00fcrkiye-76000","institution_ids":["https://openalex.org/I344703621"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5138134412","display_name":"Ibrahim DAG","orcid":"https://orcid.org/0009-0006-1191-6630","observed_orcids":["https://orcid.org/0009-0006-1191-6630"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Da\u011f, \u0130.","raw_affiliation_strings":["\u0130n\u015faat M\u00fchendisi, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0009-0006-1191-6630","affiliations":[{"raw_affiliation_string":"\u0130n\u015faat M\u00fchendisi, T\u00fcrkiye","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0849,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.7968661,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.46480000019073486,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.46480000019073486,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.15539999306201935,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.09629999846220016,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":1.0},{"id":"https://openalex.org/keywords/navier-stokes-equations","display_name":"Navier-Stokes equations","score":0.9779999852180481},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":0.8600000143051147},{"id":"https://openalex.org/keywords/hemodynamics","display_name":"hemodynamics","score":0.6639999747276306},{"id":"https://openalex.org/keywords/cerebral-hypoperfusion","display_name":"cerebral hypoperfusion","score":0.8360000252723694},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-flow","display_name":"cerebrospinal fluid flow","score":0.8650000095367432},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.6710000038146973},{"id":"https://openalex.org/keywords/computational-fluid-dynamics","display_name":"computational fluid dynamics","score":0.8119999766349792},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.7360000014305115},{"id":"https://openalex.org/keywords/nanoparticles","display_name":"nanoparticles","score":0.7269999980926514},{"id":"https://openalex.org/keywords/shear-stress","display_name":"shear stress","score":0.6269999742507935},{"id":"https://openalex.org/keywords/turbulence","display_name":"turbulent flow","score":0.6399999856948853},{"id":"https://openalex.org/keywords/viscosity","display_name":"viscosity","score":0.3370000123977661},{"id":"https://openalex.org/keywords/energy-loss","display_name":"energy loss","score":0.3720000088214874}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.632099986076355},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6040999889373779},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.5848000049591064},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.4927000105381012},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.4413999915122986},{"id":"https://openalex.org/C2994005214","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid pressure","level":3,"score":0.414000004529953},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.37400001287460327},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.37380000948905945},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.36910000443458557},{"id":"https://openalex.org/C2780801072","wikidata":"https://www.wikidata.org/wiki/Q837512","display_name":"Differential diagnosis","level":2,"score":0.32989999651908875},{"id":"https://openalex.org/C119671327","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral circulation","level":2,"score":0.31290000677108765},{"id":"https://openalex.org/C90278072","wikidata":"https://www.wikidata.org/wiki/Q216320","display_name":"Fluid dynamics","level":2,"score":0.2953000068664551},{"id":"https://openalex.org/C2994203641","wikidata":"https://www.wikidata.org/wiki/Q5712543","display_name":"Blood viscosity","level":2,"score":0.29030001163482666},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.2874999940395355},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2858999967575073},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.2799000144004822},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.2743000090122223},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.2667999863624573},{"id":"https://openalex.org/C2779701055","wikidata":"https://www.wikidata.org/wiki/Q929833","display_name":"Rare disease","level":3,"score":0.2639999985694885},{"id":"https://openalex.org/C2985453986","wikidata":"https://www.wikidata.org/wiki/Q11068","display_name":"Blood circulation","level":2,"score":0.25540000200271606}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5281/zenodo.22099443","doi":"https://doi.org/10.5281/zenodo.22099443","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22099443","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.5281/zenodo.22099444","doi":"https://doi.org/10.5281/zenodo.22099444","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22099444","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.5281/zenodo.22099443","doi":"https://doi.org/10.5281/zenodo.22099443","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22099443","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4297261420","https://openalex.org/W7134817427","https://openalex.org/W3048454922","https://openalex.org/W4404747624","https://openalex.org/W2170533522","https://openalex.org/W7207785763","https://openalex.org/W3005672607","https://openalex.org/W4411549158","https://openalex.org/W2918970524","https://openalex.org/W4390199677"],"abstract_inverted_index":{"(\"Modeling":[0],"of":[1,9,23,45,51,113,130,168,199,228],"Alzheimer's":[2,19,52,118,169,210],"Disease":[3],"Using":[4],"Navier\u2013Stokes":[5,124],"Equations":[6],"in":[7,83,86,101,110,159],"Terms":[8],"Thermal":[10],"and":[11,16,42,79,99,142,154,190,233],"Fluid":[12,173],"Sciences:":[13],"Early":[14],"Diagnosis":[15],"Treatment":[17],"Approaches\")":[18],"disease":[20,53,66,119,170,211],"is":[21,67,212],"one":[22],"the":[24,30,49,65,87,111,123,128,136,165,197,226],"most":[25],"common":[26],"neurodegenerative":[27],"diseases":[28],"among":[29],"elderly":[31],"worldwide,":[32],"characterized":[33],"by":[34,57],"progressive":[35],"memory":[36],"loss,":[37],"cognitive":[38],"dysfunction,":[39],"behavioral":[40],"changes,":[41,147],"irreversible":[43],"degeneration":[44],"nerve":[46],"cells.":[47],"Currently,":[48],"mechanisms":[50],"are":[54],"largely":[55],"explained":[56],"biochemical":[58],"processes.":[59,81],"However,":[60],"recent":[61],"research":[62],"indicates":[63],"that":[64,209],"not":[68,213],"merely":[69,214],"a":[70,107,215,220],"biological":[71],"problem;":[72],"it":[73],"also":[74,219],"involves":[75],"significant":[76,108],"hemodynamic,":[77],"thermodynamic,":[78],"biophysical":[80],"Disruptions":[82],"blood":[84],"flow":[85,134,180],"cerebral":[88,91],"vascular":[89,183],"system,":[90],"hypoperfusion,":[92],"atherosclerosis,":[93],"microvascular":[94],"occlusions,":[95],"decreased":[96],"oxygen":[97],"transport,":[98],"irregularities":[100],"cerebrospinal":[102,191],"fluid":[103,131,192,229],"circulation":[104],"can":[105],"play":[106],"role":[109],"development":[112],"Alzheimer's.":[114],"In":[115],"this":[116],"study,":[117],"was":[120,139],"investigated":[121],"using":[122,171],"equations,":[125],"which":[126],"form":[127],"basis":[129],"mechanics.":[132],"Blood":[133],"within":[135,196],"brain":[137],"vessels":[138],"mathematically":[140],"modeled,":[141],"intravascular":[143],"velocity":[144],"distributions,":[145],"pressure":[146],"shear":[148],"stresses,":[149],"energy":[150],"losses,":[151],"viscosity":[152],"effects,":[153],"turbulence":[155],"formations":[156],"were":[157,177,194],"analyzed":[158],"detail.":[160],"Furthermore,":[161],"potential":[162],"approaches":[163],"for":[164],"preonset":[166],"detection":[167],"Computational":[172],"Dynamics":[174],"(CFD)":[175],"methods":[176],"evaluated.":[178],"MRI-based":[179],"analyses,":[181],"digital":[182],"modeling,":[184],"drug":[185],"delivery":[186],"mechanisms,":[187],"nanoparticle":[188],"systems,":[189],"movement":[193],"addressed":[195],"framework":[198],"Navier\u2013Stokes-based":[200],"differential":[201],"equation":[202],"systems.":[203],"This":[204],"study":[205],"aims":[206],"to":[207,225],"demonstrate":[208],"neurological":[216],"problem,":[217],"but":[218],"multi-physics":[221],"process":[222],"directly":[223],"related":[224],"disciplines":[227],"mechanics,":[230],"thermodynamics,":[231],"biophysics,":[232],"mathematical":[234],"modeling.":[235],"[1-106]":[236]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-08-26T00:00:00"}