{"id":"https://openalex.org/W7204144388","doi":"https://doi.org/10.64898/2026.08.20.26360879","title":"Population-scale integration of tumor transcriptomics into breast cancer care: a decade of the SCAN-B initiative","display_name":"Population-scale integration of tumor transcriptomics into breast cancer care: a decade of the SCAN-B initiative","publication_year":2026,"publication_date":"2026-08-23","ids":{"openalex":"https://openalex.org/W7204144388","doi":"https://doi.org/10.64898/2026.08.20.26360879"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.20.26360879","doi":"https://doi.org/10.64898/2026.08.20.26360879","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.20.26360879","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/23/2026.08.20.26360879.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/23/2026.08.20.26360879.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016805282","display_name":"Lao H. Saal","orcid":"https://orcid.org/0000-0002-0815-1896","observed_orcids":["https://orcid.org/0000-0002-0815-1896"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Lao H. Saal","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-0815-1896","affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039218616","display_name":"Hina Dalal","orcid":"https://orcid.org/0009-0009-1610-3710","observed_orcids":["https://orcid.org/0009-0009-1610-3710"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Hina Dalal","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051319242","display_name":"Pei Meng","orcid":"https://orcid.org/0000-0002-2186-1622","observed_orcids":["https://orcid.org/0000-0002-2186-1622"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Pei Meng","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060662654","display_name":"Christian Brueffer","orcid":"https://orcid.org/0000-0002-3826-0989","observed_orcids":["https://orcid.org/0000-0002-3826-0989"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christian Brueffer","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-3826-0989","affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067795742","display_name":"Sergii Gladchuk","orcid":"https://orcid.org/0000-0002-4638-4068","observed_orcids":["https://orcid.org/0000-0002-4638-4068"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Sergii Gladchuk","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-4638-4068","affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085251030","display_name":"Sofia K. Gruvberger-Saal","orcid":"https://orcid.org/0000-0002-8478-9920","observed_orcids":["https://orcid.org/0000-0002-8478-9920"]},"institutions":[{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]},{"id":"https://openalex.org/I4210146096","display_name":"Region Sk\u00e5ne","ror":"https://ror.org/03sawy356","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210146096"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Sofia K. Gruvberger-Saal","raw_affiliation_strings":["Section for Molecular Diagnostics, Laboratory Medicine, Region Sk\u00e5ne, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section for Molecular Diagnostics, Laboratory Medicine, Region Sk\u00e5ne, Lund, Sweden","institution_ids":["https://openalex.org/I4210146096"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048408312","display_name":"Jari H\u00e4kkinen","orcid":"https://orcid.org/0000-0002-8466-9179","observed_orcids":["https://orcid.org/0000-0002-8466-9179"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jari H\u00e4kkinen","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089367055","display_name":"Nicklas Nordborg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Nicklas Nordborg","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147922622","display_name":"Minerva Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Minerva Li","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086863816","display_name":"Jeanette Valcich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jeanette Valcich","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025171844","display_name":"Ingrid A. Hedenfalk","orcid":"https://orcid.org/0000-0002-6840-3397","observed_orcids":["https://orcid.org/0000-0002-6840-3397"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ingrid Hedenfalk","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-6840-3397","affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036118135","display_name":"Anders Edsj\u00f6","orcid":"https://orcid.org/0000-0001-8783-8284","observed_orcids":["https://orcid.org/0000-0001-8783-8284"]},"institutions":[{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anders Edsj\u00f6","raw_affiliation_strings":["Section for Clinical Pathology, Department of Clinical Genetics and Pathology, Sk\u00e5ne University Hospital, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section for Clinical Pathology, Department of Clinical Genetics and Pathology, Sk\u00e5ne University Hospital, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039268198","display_name":"Fredrika Killander","orcid":"https://orcid.org/0000-0001-6266-0459","observed_orcids":["https://orcid.org/0000-0001-6266-0459"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Fredrika Killander","raw_affiliation_strings":["Department of Hematology, Oncology and Radiation Physics, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Oncology and Radiation Physics, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014246482","display_name":"Emma Nim\u00e9us","orcid":"https://orcid.org/0000-0003-0262-9083","observed_orcids":["https://orcid.org/0000-0003-0262-9083"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Emma Nim\u00e9us","raw_affiliation_strings":["Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0003-0262-9083","affiliations":[{"raw_affiliation_string":"Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061921179","display_name":"P\u00e4r\u2010Ola Bendahl","orcid":"https://orcid.org/0000-0001-8862-1845","observed_orcids":["https://orcid.org/0000-0001-8862-1845"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"P\u00e4r-Ola Bendahl","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030741648","display_name":"Carina Forsare","orcid":"https://orcid.org/0000-0002-2987-2940","observed_orcids":["https://orcid.org/0000-0002-2987-2940"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Carina Forsare","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-2987-2940","affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024663234","display_name":"Jonas Manjer","orcid":"https://orcid.org/0000-0002-3158-5289","observed_orcids":["https://orcid.org/0000-0002-3158-5289"]},"institutions":[{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jonas Manjer","raw_affiliation_strings":["Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025356792","display_name":"Janne Malina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Janne Malina","raw_affiliation_strings":["Department of Pathology, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110470448","display_name":"Martin Rehn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Martin Rehn","raw_affiliation_strings":["Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004393364","display_name":"Kristina \u00c5hsberg","orcid":"https://orcid.org/0000-0002-2652-2750","observed_orcids":["https://orcid.org/0000-0002-2652-2750"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210160669","display_name":"Hallands sjukhus Halmstad","ror":"https://ror.org/04faw9m73","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210160669"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Kristina \u00c5hsberg","raw_affiliation_strings":["Department of Surgery, Halland Hospital, Halmstad, Sweden","Division of Surgery, Department of Clinical Sciences Lund, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Halland Hospital, Halmstad, Sweden","institution_ids":["https://openalex.org/I4210160669"]},{"raw_affiliation_string":"Division of Surgery, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102978610","display_name":"Christian Ingvar","orcid":"https://orcid.org/0000-0002-7721-4619","observed_orcids":["https://orcid.org/0000-0002-7721-4619"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christian Ingvar","raw_affiliation_strings":["Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","Division of Surgery, Department of Clinical Sciences Lund, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Division of Surgery, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147940837","display_name":"Fredrik Graffner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160669","display_name":"Hallands sjukhus Halmstad","ror":"https://ror.org/04faw9m73","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210160669"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Fredrik Graffner","raw_affiliation_strings":["Department of Surgery, Halland Hospital, Halmstad, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Halland Hospital, Halmstad, Sweden","institution_ids":["https://openalex.org/I4210160669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047603602","display_name":"Lars \u00c5hlund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160669","display_name":"Hallands sjukhus Halmstad","ror":"https://ror.org/04faw9m73","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210160669"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lars \u00c5hlund","raw_affiliation_strings":["Department of Surgery, Halland Hospital, Halmstad, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Halland Hospital, Halmstad, Sweden","institution_ids":["https://openalex.org/I4210160669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057328031","display_name":"B. Asking","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148116","display_name":"Ryhov Hospital J\u00f6nk\u00f6ping","ror":"https://ror.org/053xhbr86","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210148116"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Bengt Asking","raw_affiliation_strings":["Department of Surgery, Ryhov County Hospital, J\u00f6nk\u00f6ping, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Ryhov County Hospital, J\u00f6nk\u00f6ping, Sweden","institution_ids":["https://openalex.org/I4210148116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119296560","display_name":"Maria Erngrund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088848","display_name":"Blekingesjukhuset","ror":"https://ror.org/004a7s815","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210088848"]},{"id":"https://openalex.org/I4210089631","display_name":"Region Blekinge","ror":"https://ror.org/008y4p075","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210089631"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Maria Erngrund","raw_affiliation_strings":["Department of Surgery, Blekinge County Hospital, Karlskrona, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Blekinge County Hospital, Karlskrona, Sweden","institution_ids":["https://openalex.org/I4210088848","https://openalex.org/I4210089631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042808407","display_name":"Monika Sj\u00f6vall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150155","display_name":"Centralsjukhuset Kristianstad","ror":"https://ror.org/04sn2hb78","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210150155"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Monika Sj\u00f6vall","raw_affiliation_strings":["Department of Surgery, Central Hospital Kristianstad, Kristianstad, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Central Hospital Kristianstad, Kristianstad, Sweden","institution_ids":["https://openalex.org/I4210150155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147985045","display_name":"Asa Cetti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088848","display_name":"Blekingesjukhuset","ror":"https://ror.org/004a7s815","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210088848"]},{"id":"https://openalex.org/I4210089631","display_name":"Region Blekinge","ror":"https://ror.org/008y4p075","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210089631"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Asa Cetti","raw_affiliation_strings":["Department of Surgery, Blekinge County Hospital, Karlskrona, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Blekinge County Hospital, Karlskrona, Sweden","institution_ids":["https://openalex.org/I4210088848","https://openalex.org/I4210089631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019916683","display_name":"Tor Svensj\u00f6","orcid":"https://orcid.org/0000-0003-3203-0303","observed_orcids":["https://orcid.org/0000-0003-3203-0303"]},"institutions":[{"id":"https://openalex.org/I4210150155","display_name":"Centralsjukhuset Kristianstad","ror":"https://ror.org/04sn2hb78","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210150155"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Tor Svensj\u00f6","raw_affiliation_strings":["Department of Surgery, Central Hospital Kristianstad, Kristianstad, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Central Hospital Kristianstad, Kristianstad, Sweden","institution_ids":["https://openalex.org/I4210150155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035299794","display_name":"Heitti Teder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150155","display_name":"Centralsjukhuset Kristianstad","ror":"https://ror.org/04sn2hb78","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210150155"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Heitti Teder","raw_affiliation_strings":["Department of Surgery, Central Hospital Kristianstad, Kristianstad, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Central Hospital Kristianstad, Kristianstad, Sweden","institution_ids":["https://openalex.org/I4210150155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147988463","display_name":"Johanna Bjorkman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157561","display_name":"V\u00e4xj\u00f6 Kommun","ror":"https://ror.org/04hwmbc03","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210157561"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Johanna Bj\u00f6rkman","raw_affiliation_strings":["Department of Surgery, V\u00e4xj\u00f6 Central Hospital, V\u00e4xj\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, V\u00e4xj\u00f6 Central Hospital, V\u00e4xj\u00f6, Sweden","institution_ids":["https://openalex.org/I4210157561"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147974024","display_name":"Lena Myrskog","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157561","display_name":"V\u00e4xj\u00f6 Kommun","ror":"https://ror.org/04hwmbc03","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210157561"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lena Myrskog","raw_affiliation_strings":["Department of Surgery, V\u00e4xj\u00f6 Central Hospital, V\u00e4xj\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, V\u00e4xj\u00f6 Central Hospital, V\u00e4xj\u00f6, Sweden","institution_ids":["https://openalex.org/I4210157561"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006132154","display_name":"Anna\u2010Karin Falck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132623","display_name":"Helsingborgs lasarett","ror":"https://ror.org/03am3jt82","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210132623"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anna-Karin Falck","raw_affiliation_strings":["Department of Surgery, Helsingborg Hospital, Helsingborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Helsingborg Hospital, Helsingborg, Sweden","institution_ids":["https://openalex.org/I4210132623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110041477","display_name":"Ann-Christine K\u00e4llstr\u00f6m","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132623","display_name":"Helsingborgs lasarett","ror":"https://ror.org/03am3jt82","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210132623"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ann-Christine K\u00e4llstr\u00f6m","raw_affiliation_strings":["Department of Surgery, Helsingborg Hospital, Helsingborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Helsingborg Hospital, Helsingborg, Sweden","institution_ids":["https://openalex.org/I4210132623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062857865","display_name":"Zakaria Einbeigi","orcid":"https://orcid.org/0000-0003-2507-7197","observed_orcids":["https://orcid.org/0000-0003-2507-7197"]},"institutions":[{"id":"https://openalex.org/I4210107627","display_name":"S\u00f6dra \u00c4lvsborg Hospital","ror":"https://ror.org/01qas6g18","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210107627"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Zakaria Einbeigi","raw_affiliation_strings":["Department of Medicine and Oncology, Southern \u00c4lvsborg Hospital, Bor\u00e5s, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Oncology, Southern \u00c4lvsborg Hospital, Bor\u00e5s, Sweden","institution_ids":["https://openalex.org/I4210107627"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148037853","display_name":"Patricia Ribeiro Braganca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107627","display_name":"S\u00f6dra \u00c4lvsborg Hospital","ror":"https://ror.org/01qas6g18","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210107627"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Patr\u00edcia Ribeiro Bragan\u00e7a","raw_affiliation_strings":["Department of Medicine and Oncology, Southern \u00c4lvsborg Hospital, Bor\u00e5s, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Oncology, Southern \u00c4lvsborg Hospital, Bor\u00e5s, Sweden","institution_ids":["https://openalex.org/I4210107627"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065433718","display_name":"Henrik Lindman","orcid":"https://orcid.org/0000-0002-5871-268X","observed_orcids":["https://orcid.org/0000-0002-5871-268X"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Henrik Lindman","raw_affiliation_strings":["Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012982051","display_name":"Tobias Sj\u00f6blom","orcid":"https://orcid.org/0000-0001-6668-4140","observed_orcids":["https://orcid.org/0000-0001-6668-4140"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Tobias Sj\u00f6blom","raw_affiliation_strings":["Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070951926","display_name":"Martin Malmberg","orcid":"https://orcid.org/0000-0002-9500-8982","observed_orcids":["https://orcid.org/0000-0002-9500-8982"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Martin Malmberg","raw_affiliation_strings":["Department of Hematology, Oncology and Radiation Physics, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Oncology and Radiation Physics, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109431883","display_name":"Christer Larsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christer Larsson","raw_affiliation_strings":["Division of Translational Cancer Research, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Translational Cancer Research, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045322799","display_name":"Anna Ehinger","orcid":"https://orcid.org/0000-0001-9225-7396","observed_orcids":["https://orcid.org/0000-0001-9225-7396"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anna Ehinger","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Section for Clinical Pathology, Department of Clinical Genetics and Pathology, Sk\u00e5ne University Hospital, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0001-9225-7396","affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Section for Clinical Pathology, Department of Clinical Genetics and Pathology, Sk\u00e5ne University Hospital, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010340306","display_name":"Lisa Ryd\u00e9n","orcid":"https://orcid.org/0000-0001-7515-3130","observed_orcids":["https://orcid.org/0000-0001-7515-3130"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lisa Ryd\u00e9n","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Department of Hematology, Oncology and Radiation Physics, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0001-7515-3130","affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Department of Hematology, Oncology and Radiation Physics, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108833264","display_name":"Niklas Loman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Niklas Loman","raw_affiliation_strings":["Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Section for Clinical Pathology, Department of Clinical Genetics and Pathology, Sk\u00e5ne University Hospital, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Interdisciplinary Research on Cancer and Equity in Women, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Section for Clinical Pathology, Department of Clinical Genetics and Pathology, Sk\u00e5ne University Hospital, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008691716","display_name":"Cecilia Hegardt","orcid":"https://orcid.org/0000-0003-1019-9992","observed_orcids":["https://orcid.org/0000-0003-1019-9992"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Cecilia Hegardt","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033640021","display_name":"\u00c5ke Borg","orcid":"https://orcid.org/0000-0002-5793-132X","observed_orcids":["https://orcid.org/0000-0002-5793-132X"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"\u00c5ke Borg","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040610749","display_name":"Johan Vallon\u2010Christersson","orcid":"https://orcid.org/0000-0002-2195-0385","observed_orcids":["https://orcid.org/0000-0002-2195-0385"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Johan Vallon-Christersson","raw_affiliation_strings":["Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","Lund University Cancer Center, Lund University, Lund, Sweden","Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-2195-0385","affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Lund University Cancer Center, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Sk\u00e5ne University Hospital Comprehensive Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I4210137844"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5016805282"],"corresponding_institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8550000190734863},{"id":"https://openalex.org/keywords/rna-sequencing","display_name":"RNA sequencing","score":0.4580000042915344},{"id":"https://openalex.org/keywords/molecular-subtypes","display_name":"molecular subtypes","score":0.8790000081062317},{"id":"https://openalex.org/keywords/risk-of-recurrence","display_name":"recurrence risk","score":0.8920000195503235},{"id":"https://openalex.org/keywords/somatic-mutations","display_name":"somatic mutations","score":0.9440000057220459},{"id":"https://openalex.org/keywords/biospecimen-collection","display_name":"biospecimen collection","score":0.6809999942779541},{"id":"https://openalex.org/keywords/treatment-patterns","display_name":"treatment patterns","score":0.6060000061988831},{"id":"https://openalex.org/keywords/recurrence-free-survival","display_name":"recurrence-free survival","score":0.7689999938011169},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9350000023841858},{"id":"https://openalex.org/keywords/biomarker-implementation","display_name":"biomarker implementation","score":0.5049999952316284},{"id":"https://openalex.org/keywords/real-world-outcomes","display_name":"real-world outcomes","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7901999950408936},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7712000012397766},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6133000254631042},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6032000184059143},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.5024999976158142},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4869999885559082},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.486299991607666},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.45249998569488525},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.3817000091075897},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3758000135421753},{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.36899998784065247},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.34529998898506165},{"id":"https://openalex.org/C179786068","wikidata":"https://www.wikidata.org/wiki/Q16257937","display_name":"Molecular diagnostics","level":2,"score":0.3240000009536743},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.3109000027179718},{"id":"https://openalex.org/C3019646584","wikidata":"https://www.wikidata.org/wiki/Q2311855","display_name":"Molecular biomarkers","level":2,"score":0.30979999899864197},{"id":"https://openalex.org/C128544194","wikidata":"https://www.wikidata.org/wiki/Q474859","display_name":"Translational research","level":2,"score":0.2928999960422516},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.2838999927043915},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2761000096797943},{"id":"https://openalex.org/C2777757722","wikidata":"https://www.wikidata.org/wiki/Q848318","display_name":"Mastectomy","level":4,"score":0.27379998564720154},{"id":"https://openalex.org/C2775930923","wikidata":"https://www.wikidata.org/wiki/Q12859063","display_name":"Metastatic breast cancer","level":4,"score":0.25839999318122864},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.25459998846054077},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.25119999051094055},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.2506999969482422}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.08.20.26360879","doi":"https://doi.org/10.64898/2026.08.20.26360879","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.20.26360879","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/23/2026.08.20.26360879.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.08.20.26360879","doi":"https://doi.org/10.64898/2026.08.20.26360879","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.20.26360879","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/08/23/2026.08.20.26360879.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4246870193","display_name":"The Translational Cancer Faster Forward postdoctoral programme \u2013 CanFaster-ER","funder_award_id":"847583","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204144388.pdf","grobid_xml":"https://content.openalex.org/works/W7204144388.grobid-xml"},"referenced_works_count":67,"referenced_works":["https://openalex.org/W1852087234","https://openalex.org/W1965856472","https://openalex.org/W1988026472","https://openalex.org/W1988406056","https://openalex.org/W1994303266","https://openalex.org/W2008233728","https://openalex.org/W2035450351","https://openalex.org/W2048470939","https://openalex.org/W2061909637","https://openalex.org/W2067287567","https://openalex.org/W2067324969","https://openalex.org/W2085302318","https://openalex.org/W2090890710","https://openalex.org/W2097337885","https://openalex.org/W2104610456","https://openalex.org/W2105882193","https://openalex.org/W2106714771","https://openalex.org/W2106833357","https://openalex.org/W2112686497","https://openalex.org/W2114537434","https://openalex.org/W2115528316","https://openalex.org/W2116035619","https://openalex.org/W2116805592","https://openalex.org/W2128613144","https://openalex.org/W2128985829","https://openalex.org/W2132619562","https://openalex.org/W2134626505","https://openalex.org/W2135557996","https://openalex.org/W2141414987","https://openalex.org/W2150542002","https://openalex.org/W2160042082","https://openalex.org/W2169076357","https://openalex.org/W2337669715","https://openalex.org/W2341230536","https://openalex.org/W2403389346","https://openalex.org/W2517421365","https://openalex.org/W2558458383","https://openalex.org/W2619980482","https://openalex.org/W2753267414","https://openalex.org/W2768579001","https://openalex.org/W2787188812","https://openalex.org/W2792135005","https://openalex.org/W2805734855","https://openalex.org/W2898789830","https://openalex.org/W2911718257","https://openalex.org/W2947890877","https://openalex.org/W2950382962","https://openalex.org/W2964026708","https://openalex.org/W2969520627","https://openalex.org/W2969735012","https://openalex.org/W2976898289","https://openalex.org/W3003870469","https://openalex.org/W3004781275","https://openalex.org/W3080522337","https://openalex.org/W3128787277","https://openalex.org/W3155215767","https://openalex.org/W3195237310","https://openalex.org/W3199420266","https://openalex.org/W4220997016","https://openalex.org/W4293728835","https://openalex.org/W4318203454","https://openalex.org/W4387770134","https://openalex.org/W4388694832","https://openalex.org/W4389681263","https://openalex.org/W4392384788","https://openalex.org/W4403471538","https://openalex.org/W4404838998"],"related_works":["https://openalex.org/W2115528316","https://openalex.org/W2316183298","https://openalex.org/W7095395084","https://openalex.org/W2594661579","https://openalex.org/W2787188812","https://openalex.org/W3119428931","https://openalex.org/W4413184440","https://openalex.org/W2945224952","https://openalex.org/W1986859843","https://openalex.org/W2042736985"],"abstract_inverted_index":{"ABSTRACT":[0],"Background":[1],"Population-scale":[2],"molecular":[3,44,57,123,139,213,223,247,260,279,293,317,348,372],"profiling":[4,45,140,214,318,349],"integrated":[5,322],"into":[6,59,145,257,295,323],"routine":[7,146,258,324,362,391],"healthcare":[8],"could":[9],"accelerate":[10],"biomarker":[11,351,374],"discovery,":[12],"validation,":[13,377],"and":[14,19,51,90,95,113,125,127,177,226,240,243,249,264,281,288,292,335,347,353,376,378,381],"implementation,":[15,380],"but":[16],"the":[17,70,135,142,198,227,252,296],"feasibility":[18],"sustainability":[20],"of":[21,76,137,174,185,197,208,217,245,290,310,357],"such":[22],"an":[23,53],"approach":[24],"have":[25],"rarely":[26],"been":[27],"demonstrated":[28],"prospectively.":[29],"The":[30,191],"Sweden":[31],"Cancerome":[32],"Analysis":[33],"Network":[34],"-":[35],"Breast":[36],"(SCAN-B)":[37],"Initiative":[38],"was":[39,194,255],"established":[40],"to":[41,109,355],"integrate":[42],"prospective":[43,237,285,345],"with":[46,80,100,212,304,390],"population-based":[47,233,316,371],"breast":[48,83,103,154,200,325],"cancer":[49,84,104,155,201,326,392],"care":[50,327],"create":[52],"infrastructure":[54,298],"for":[55,385],"translating":[56],"discoveries":[58],"clinical":[60,147,210,259,277,379],"practice":[61],"(":[62],"ClinicalTrials.gov":[63,396],"identifier":[64,397],"NCT02306096":[65,398],").":[66],"Methods":[67],"We":[68,132],"evaluated":[69],"first":[71],"10":[72],"full":[73],"calendar":[74],"years":[75],"SCAN-B,":[77],"encompassing":[78],"patients":[79,158,176,274,307],"primary":[81],"invasive":[82],"enrolled":[85,162,175,192],"between":[86],"August":[87],"30,":[88],"2010":[89],"December":[91],"31,":[92],"2020.":[93],"Enrollment":[94],"biospecimen":[96],"collection":[97],"were":[98,130,160,170],"compared":[99],"all":[101],"eligible":[102,153],"diagnoses":[105],"in":[106,231,262,266,361],"participating":[107,164],"hospitals":[108],"assess":[110],"population":[111,202,333],"coverage":[112,334],"representativeness.":[114,336],"Clinicopathological":[115],"characteristics,":[116],"treatments,":[117],"recurrence-free":[118],"survival,":[119,121],"overall":[120],"RNA-sequencing-based":[122,278],"subtypes":[124],"risk-of-recurrence,":[126,225],"somatic":[128,228],"mutations":[129],"evaluated.":[131],"additionally":[133],"report":[134],"translation":[136],"SCAN-B":[138,253,286,342],"from":[141,172,180,344],"research":[143,297,389],"setting":[144],"diagnostics.":[148],"Results":[149],"Among":[150],"16,381":[151],"estimated":[152],"diagnoses,":[156],"13,940":[157],"(85.1%)":[159],"prospectively":[161],"across":[163,203],"Swedish":[165],"hospitals.":[166],"Baseline":[167],"blood":[168],"samples":[169,291],"obtained":[171],"98.4%":[173],"tumor":[178,187],"specimens":[179],"71.1%;":[181],"9,323":[182],"tumors":[183],"(94.0%":[184],"submitted":[186],"specimens)":[188],"underwent":[189],"RNA-sequencing.":[190],"cohort":[193],"broadly":[195],"representative":[196],"underlying":[199],"major":[204],"clinicopathological":[205],"characteristics.":[206],"Integration":[207],"longitudinal":[209],"data":[211,294],"enabled":[215],"characterization":[216],"real-world":[218],"treatment":[219],"patterns,":[220],"long-term":[221],"outcomes,":[222],"subtypes,":[224],"mutational":[229],"landscape":[230],"this":[232],"cohort.":[234],"Building":[235],"on":[236],"real-time":[238],"RNA-sequencing":[239],"subsequent":[241],"development":[242,352],"validation":[244,354],"single-sample":[246],"subtype":[248,280],"risk-of-recurrence":[250,282],"predictors,":[251],"workflow":[254],"transferred":[256],"diagnostics":[261],"Sk\u00e5ne":[263],"Blekinge":[265],"2021.":[267],"Through":[268],"January":[269,311],"2026,":[270],"more":[271,338],"than":[272,339],"3,000":[273],"had":[275],"received":[276],"reports,":[283],"while":[284,330],"enrollment":[287,301],"transfer":[289],"continued.":[299],"Patient":[300],"continues":[302],"prospectively,":[303],"over":[305],"23,000":[306],"accrued":[308],"as":[309],"2026.":[312],"Conclusions":[313],"A":[314],"prospective,":[315],"program":[319],"can":[320],"be":[321],"at":[328],"scale":[329],"maintaining":[331],"high":[332],"Over":[337],"a":[340,367,383],"decade,":[341],"progressed":[343],"biosampling":[346],"through":[350],"implementation":[356],"RNA":[358],"sequencing-based":[359],"testing":[360],"healthcare.":[363],"This":[364],"model":[365],"establishes":[366],"continuous":[368],"framework":[369],"linking":[370],"research,":[373],"discovery":[375],"provides":[382],"strategy":[384],"integrating":[386],"precision":[387],"oncology":[388],"care.":[393],"Trial":[394],"registration":[395]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-08-25T00:00:00"}