{"id":"https://openalex.org/W7204127498","doi":"https://doi.org/10.1007/s42399-026-02646-8","title":"Renal Function Decline in Asian Patients with Non-Valvular Atrial Fibrillation Receiving Direct Oral Anticoagulants: A Multicentre Real-World Study","display_name":"Renal Function Decline in Asian Patients with Non-Valvular Atrial Fibrillation Receiving Direct Oral Anticoagulants: A Multicentre Real-World Study","publication_year":2026,"publication_date":"2026-08-24","ids":{"openalex":"https://openalex.org/W7204127498","doi":"https://doi.org/10.1007/s42399-026-02646-8"},"language":"en","primary_location":{"id":"doi:10.1007/s42399-026-02646-8","doi":"https://doi.org/10.1007/s42399-026-02646-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s42399-026-02646-8","pdf_url":null,"source":{"id":"https://openalex.org/S4210220763","display_name":"SN Comprehensive Clinical Medicine","issn_l":"2523-8973","issn":["2523-8973"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SN Comprehensive Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071155576","display_name":"Hock Peng Koh","orcid":"https://orcid.org/0000-0003-2676-7755","observed_orcids":["https://orcid.org/0000-0003-2676-7755"]},"institutions":[{"id":"https://openalex.org/I105292261","display_name":"Ministry of Health","ror":"https://ror.org/05ddxe180","country_code":"MY","type":"government","lineage":["https://openalex.org/I105292261"]},{"id":"https://openalex.org/I2799421553","display_name":"Hospital Kuala Lumpur","ror":"https://ror.org/03n0nnh89","country_code":"MY","type":"healthcare","lineage":["https://openalex.org/I2799421553"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Hock Peng Koh","raw_affiliation_strings":["Pharmacy Department, Hospital Kuala Lumpur, Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur, 50586, Malaysia"],"raw_orcid":"https://orcid.org/0000-0003-2676-7755","affiliations":[{"raw_affiliation_string":"Pharmacy Department, Hospital Kuala Lumpur, Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur, 50586, Malaysia","institution_ids":["https://openalex.org/I105292261","https://openalex.org/I2799421553"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029254927","display_name":"Jivanraj R. Nagarajah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105292261","display_name":"Ministry of Health","ror":"https://ror.org/05ddxe180","country_code":"MY","type":"government","lineage":["https://openalex.org/I105292261"]},{"id":"https://openalex.org/I2799421553","display_name":"Hospital Kuala Lumpur","ror":"https://ror.org/03n0nnh89","country_code":"MY","type":"healthcare","lineage":["https://openalex.org/I2799421553"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Jivanraj R. Nagarajah","raw_affiliation_strings":["Pharmacy Department, Hospital Kuala Lumpur, Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur, 50586, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Department, Hospital Kuala Lumpur, Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur, 50586, Malaysia","institution_ids":["https://openalex.org/I105292261","https://openalex.org/I2799421553"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147928943","display_name":"Parwathi K. Sellamuthu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105292261","display_name":"Ministry of Health","ror":"https://ror.org/05ddxe180","country_code":"MY","type":"government","lineage":["https://openalex.org/I105292261"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Parwathi K. Sellamuthu","raw_affiliation_strings":["Pharmacy Department, Hospital Sultan Idris Shah, Ministry of Health Malaysia, Jalan Puchong, Kajang, 43000, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Department, Hospital Sultan Idris Shah, Ministry of Health Malaysia, Jalan Puchong, Kajang, 43000, Selangor, Malaysia","institution_ids":["https://openalex.org/I105292261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102937137","display_name":"C.Z.F. Chua","orcid":"https://orcid.org/0009-0005-6683-8978","observed_orcids":["https://orcid.org/0009-0005-6683-8978"]},"institutions":[{"id":"https://openalex.org/I105292261","display_name":"Ministry of Health","ror":"https://ror.org/05ddxe180","country_code":"MY","type":"government","lineage":["https://openalex.org/I105292261"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Chelfi Zhi Fei Chua","raw_affiliation_strings":["Pharmacy Department, Sarawak Heart Centre, Kuching - Samarahan Expressway, Ministry of Health Malaysia, Kota Samarahan, Sarawak, 94300, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Department, Sarawak Heart Centre, Kuching - Samarahan Expressway, Ministry of Health Malaysia, Kota Samarahan, Sarawak, 94300, Malaysia","institution_ids":["https://openalex.org/I105292261"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047865541","display_name":"Shantini Radhakrishnan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105292261","display_name":"Ministry of Health","ror":"https://ror.org/05ddxe180","country_code":"MY","type":"government","lineage":["https://openalex.org/I105292261"]},{"id":"https://openalex.org/I4210100512","display_name":"Hospital Tuanku Ja\u2019afar","ror":"https://ror.org/00jxnw682","country_code":"MY","type":"healthcare","lineage":["https://openalex.org/I4210100512"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Shantini Radhakrishnan","raw_affiliation_strings":["Pharmacy Department, Hospital Tuanku Ja\u2019afar, Ministry of Health Malaysia, Jalan Rasah, Bukit Rasah, Seremban, Negeri Sembilan, 70300, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Department, Hospital Tuanku Ja\u2019afar, Ministry of Health Malaysia, Jalan Rasah, Bukit Rasah, Seremban, Negeri Sembilan, 70300, Malaysia","institution_ids":["https://openalex.org/I105292261","https://openalex.org/I4210100512"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5071155576"],"corresponding_institution_ids":["https://openalex.org/I105292261","https://openalex.org/I2799421553"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.61343002,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renal-function-decline","display_name":"renal function decline","score":0.9259999990463257},{"id":"https://openalex.org/keywords/non-valvular-atrial-fibrillation","display_name":"non-valvular atrial fibrillation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/direct-oral-anticoagulants","display_name":"direct oral anticoagulants","score":1.0},{"id":"https://openalex.org/keywords/estimated-glomerular-filtration-rate","display_name":"estimated glomerular filtration rate","score":0.9459999799728394},{"id":"https://openalex.org/keywords/apixaban","display_name":"apixaban","score":0.9860000014305115},{"id":"https://openalex.org/keywords/rivaroxaban","display_name":"rivaroxaban","score":1.0},{"id":"https://openalex.org/keywords/dabigatran","display_name":"dabigatran","score":1.0},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9769999980926514},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.6489999890327454},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":0.9829999804496765},{"id":"https://openalex.org/keywords/asian-patients","display_name":"Asian patients","score":0.8640000224113464},{"id":"https://openalex.org/keywords/renal-function-monitoring","display_name":"renal function monitoring","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9387999773025513},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.7626000046730042},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.7567999958992004},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.7364000082015991},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7017999887466431},{"id":"https://openalex.org/C2778810321","wikidata":"https://www.wikidata.org/wiki/Q419345","display_name":"Dabigatran","level":4,"score":0.6524999737739563},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.49810001254081726},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.46560001373291016},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4578000009059906},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.43149998784065247},{"id":"https://openalex.org/C2778661090","wikidata":"https://www.wikidata.org/wiki/Q420262","display_name":"Rivaroxaban","level":4,"score":0.40380001068115234},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.36629998683929443},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.3637000024318695},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.33079999685287476},{"id":"https://openalex.org/C2780638905","wikidata":"https://www.wikidata.org/wiki/Q414462","display_name":"Apixaban","level":5,"score":0.3303000032901764},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.32899999618530273},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.2906999886035919},{"id":"https://openalex.org/C2776301958","wikidata":"https://www.wikidata.org/wiki/Q407431","display_name":"Warfarin","level":3,"score":0.2791999876499176},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.2766000032424927},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.2685999870300293},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.26840001344680786},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.26030001044273376},{"id":"https://openalex.org/C2779668873","wikidata":"https://www.wikidata.org/wiki/Q6693756","display_name":"Lower risk","level":3,"score":0.25609999895095825}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s42399-026-02646-8","doi":"https://doi.org/10.1007/s42399-026-02646-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s42399-026-02646-8","pdf_url":null,"source":{"id":"https://openalex.org/S4210220763","display_name":"SN Comprehensive Clinical Medicine","issn_l":"2523-8973","issn":["2523-8973"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SN Comprehensive Clinical Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W594767912","https://openalex.org/W1978587266","https://openalex.org/W2086570276","https://openalex.org/W2093754226","https://openalex.org/W2126858523","https://openalex.org/W2162499932","https://openalex.org/W2165242637","https://openalex.org/W2421809065","https://openalex.org/W2469001618","https://openalex.org/W2473405365","https://openalex.org/W2626499917","https://openalex.org/W2768325747","https://openalex.org/W2776055733","https://openalex.org/W2889396982","https://openalex.org/W2944455259","https://openalex.org/W3000199213","https://openalex.org/W3021617208","https://openalex.org/W3193095852","https://openalex.org/W4220770985","https://openalex.org/W4295681681","https://openalex.org/W4405868177","https://openalex.org/W4406799092","https://openalex.org/W4410941473","https://openalex.org/W4412196608","https://openalex.org/W4414754124"],"related_works":["https://openalex.org/W4410941473","https://openalex.org/W4224286574","https://openalex.org/W4412196608","https://openalex.org/W4306255074","https://openalex.org/W3209260113","https://openalex.org/W4408471051","https://openalex.org/W4220770985","https://openalex.org/W3021617208","https://openalex.org/W4383067322","https://openalex.org/W4388600367"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-08-25T00:00:00"}