{"id":"https://openalex.org/W7204115607","doi":"https://doi.org/10.64898/2026.08.20.745964","title":"Spatio-temporally regulated maternal RNA decay factor essential for zebrafish development","display_name":"Spatio-temporally regulated maternal RNA decay factor essential for zebrafish development","publication_year":2026,"publication_date":"2026-08-24","ids":{"openalex":"https://openalex.org/W7204115607","doi":"https://doi.org/10.64898/2026.08.20.745964","pmid":"https://pubmed.ncbi.nlm.nih.gov/42922634","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13684608"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.20.745964","doi":"https://doi.org/10.64898/2026.08.20.745964","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.20.745964","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.64898/2026.08.20.745964","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025154531","display_name":"Gopal Kushawah","orcid":"https://orcid.org/0000-0002-3608-1530","observed_orcids":["https://orcid.org/0000-0002-3608-1530"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gopal Kushawah","raw_affiliation_strings":["Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041081628","display_name":"Victor Daniel Aldas-Bulos","orcid":"https://orcid.org/0000-0002-7569-775X","observed_orcids":["https://orcid.org/0000-0002-7569-775X"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victor Daniel Aldas Bulos","raw_affiliation_strings":["Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046157901","display_name":"Danielson Baia Amaral","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danielson Baia Amaral","raw_affiliation_strings":["Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047274241","display_name":"Huzaifa Hassan","orcid":"https://orcid.org/0000-0003-0624-0198","observed_orcids":["https://orcid.org/0000-0003-0624-0198"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huzaifa Hassan","raw_affiliation_strings":["Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047133912","display_name":"Stephanie H. Nowotarski","orcid":"https://orcid.org/0000-0003-2569-1939","observed_orcids":["https://orcid.org/0000-0003-2569-1939"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephanie H. Nowotarski","raw_affiliation_strings":["Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA"],"raw_orcid":"https://orcid.org/0000-0003-2569-1939","affiliations":[{"raw_affiliation_string":"Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067621634","display_name":"Ariel Bazzini","orcid":"https://orcid.org/0000-0002-2251-5174","observed_orcids":["https://orcid.org/0000-0002-2251-5174"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]},{"id":"https://openalex.org/I4210128618","display_name":"University of Kansas Medical Center","ror":"https://ror.org/036c9yv20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210128618"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ariel A. Bazzini","raw_affiliation_strings":["Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA","Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA"],"raw_orcid":"https://orcid.org/0000-0002-2251-5174","affiliations":[{"raw_affiliation_string":"Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA","institution_ids":["https://openalex.org/I4210128618"]},{"raw_affiliation_string":"Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA","institution_ids":["https://openalex.org/I114131015"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5067621634"],"corresponding_institution_ids":["https://openalex.org/I114131015","https://openalex.org/I4210128618"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.01209999993443489,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/maternal-to-zygotic-transition","display_name":"maternal-to-zygotic transition","score":0.9520000219345093},{"id":"https://openalex.org/keywords/spatiotemporal-control","display_name":"spatiotemporal control","score":0.6660000085830688},{"id":"https://openalex.org/keywords/au-rich-elements","display_name":"AU-rich elements","score":0.8629999756813049},{"id":"https://openalex.org/keywords/deadenylation","display_name":"deadenylation","score":0.8899999856948853},{"id":"https://openalex.org/keywords/zebrafish-embryonic-development","display_name":"zebrafish embryonic development","score":0.7730000019073486},{"id":"https://openalex.org/keywords/gametogenesis","display_name":"gametogenesis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/zygotic-genome-activation","display_name":"zygotic genome activation","score":0.7519999742507935},{"id":"https://openalex.org/keywords/maternal-mrna","display_name":"maternal mRNA","score":0.32600000500679016}],"concepts":[{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.7947999835014343},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7479000091552734},{"id":"https://openalex.org/C109825262","wikidata":"https://www.wikidata.org/wiki/Q1139164","display_name":"Germline","level":3,"score":0.609499990940094},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6046000123023987},{"id":"https://openalex.org/C41282012","wikidata":"https://www.wikidata.org/wiki/Q3928341","display_name":"RNA-binding protein","level":4,"score":0.5145000219345093},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5141000151634216},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4740999937057495},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4578999876976013},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4462999999523163},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.4325000047683716},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.41819998621940613},{"id":"https://openalex.org/C70219777","wikidata":"https://www.wikidata.org/wiki/Q14911527","display_name":"Nonsense-mediated decay","level":5,"score":0.3950999975204468},{"id":"https://openalex.org/C28748434","wikidata":"https://www.wikidata.org/wiki/Q170145","display_name":"Zygote","level":4,"score":0.39480000734329224},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.39340001344680786},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.36480000615119934},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.3628999888896942},{"id":"https://openalex.org/C17341445","wikidata":"https://www.wikidata.org/wiki/Q6786633","display_name":"Maternal to zygotic transition","level":5,"score":0.3531999886035919},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.3483999967575073},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.33809998631477356},{"id":"https://openalex.org/C199216141","wikidata":"https://www.wikidata.org/wiki/Q4995178","display_name":"Conserved sequence","level":4,"score":0.30649998784065247},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.3025999963283539},{"id":"https://openalex.org/C2781291010","wikidata":"https://www.wikidata.org/wiki/Q178580","display_name":"Period (music)","level":2,"score":0.29339998960494995},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.29280000925064087},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2906999886035919},{"id":"https://openalex.org/C2778961482","wikidata":"https://www.wikidata.org/wiki/Q25241","display_name":"Vertebrate","level":3,"score":0.27619999647140503},{"id":"https://openalex.org/C53479859","wikidata":"https://www.wikidata.org/wiki/Q3064200","display_name":"Trans-acting","level":4,"score":0.25130000710487366}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.64898/2026.08.20.745964","doi":"https://doi.org/10.64898/2026.08.20.745964","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.20.745964","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:42922634","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42922634","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13684608","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13684608/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.64898/2026.08.20.745964","doi":"https://doi.org/10.64898/2026.08.20.745964","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.20.745964","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2223054252","display_name":null,"funder_award_id":"OD034161","funder_id":"https://openalex.org/F4320337349","funder_display_name":"NIH Office of the Director"},{"id":"https://openalex.org/G5965882343","display_name":null,"funder_award_id":"GM161459","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000857134","display_name":"Small translated ORFs in the 3'UTR enhance translation in vertebrates","funder_award_id":"R01GM136849","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320310084","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609"},{"id":"https://openalex.org/F4320337349","display_name":"NIH Office of the Director","ror":"https://ror.org/00fj8a872"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":85,"referenced_works":["https://openalex.org/W1606301060","https://openalex.org/W1799971474","https://openalex.org/W1963822801","https://openalex.org/W1970827552","https://openalex.org/W1972175499","https://openalex.org/W1983730511","https://openalex.org/W1989435072","https://openalex.org/W1996070118","https://openalex.org/W2004635090","https://openalex.org/W2009050803","https://openalex.org/W2013782508","https://openalex.org/W2026570758","https://openalex.org/W2030039748","https://openalex.org/W2030892205","https://openalex.org/W2031853229","https://openalex.org/W2034689969","https://openalex.org/W2038254017","https://openalex.org/W2045449473","https://openalex.org/W2049868101","https://openalex.org/W2053219805","https://openalex.org/W2064442036","https://openalex.org/W2069089843","https://openalex.org/W2101815618","https://openalex.org/W2108284151","https://openalex.org/W2117921076","https://openalex.org/W2122798077","https://openalex.org/W2132985564","https://openalex.org/W2136400757","https://openalex.org/W2142908460","https://openalex.org/W2144157815","https://openalex.org/W2145989110","https://openalex.org/W2150014745","https://openalex.org/W2152083180","https://openalex.org/W2298977477","https://openalex.org/W2326766364","https://openalex.org/W2399214430","https://openalex.org/W2416793874","https://openalex.org/W2495238549","https://openalex.org/W2529441459","https://openalex.org/W2586247640","https://openalex.org/W2759506905","https://openalex.org/W2796449627","https://openalex.org/W2903481608","https://openalex.org/W2903862932","https://openalex.org/W2950756610","https://openalex.org/W2951614277","https://openalex.org/W3015411398","https://openalex.org/W3036776958","https://openalex.org/W3048341121","https://openalex.org/W3113710960","https://openalex.org/W3118798023","https://openalex.org/W3152172570","https://openalex.org/W3158613520","https://openalex.org/W3169412981","https://openalex.org/W3179842624","https://openalex.org/W4205951818","https://openalex.org/W4220803283","https://openalex.org/W4229333368","https://openalex.org/W4232766636","https://openalex.org/W4292055839","https://openalex.org/W4307038231","https://openalex.org/W4308660994","https://openalex.org/W4318817249","https://openalex.org/W4319596205","https://openalex.org/W4361205078","https://openalex.org/W4366607759","https://openalex.org/W4377194546","https://openalex.org/W4386278628","https://openalex.org/W4387779329","https://openalex.org/W4387823519","https://openalex.org/W4388041545","https://openalex.org/W4391151007","https://openalex.org/W4392958606","https://openalex.org/W4394678773","https://openalex.org/W4394769654","https://openalex.org/W4396521167","https://openalex.org/W4399281183","https://openalex.org/W4399775937","https://openalex.org/W4402631803","https://openalex.org/W4404169376","https://openalex.org/W4404670607","https://openalex.org/W4408495006","https://openalex.org/W4416257429","https://openalex.org/W7128157664","https://openalex.org/W7135049868"],"related_works":["https://openalex.org/W4404169376","https://openalex.org/W7204477033","https://openalex.org/W2788303851","https://openalex.org/W2586247640","https://openalex.org/W2991221936","https://openalex.org/W4990207","https://openalex.org/W3090998674","https://openalex.org/W2298977477","https://openalex.org/W2513277360","https://openalex.org/W2796449627"],"abstract_inverted_index":{"Summary":[0],"Maternal":[1],"mRNA":[2,132,149],"decay":[3,92,153],"is":[4,144,162],"essential":[5,163],"for":[6,164],"the":[7,29,41,120,125,135],"M":[8],"aternal-to-":[9],"Z":[10],"ygotic":[11],"T":[12],"ransition":[13],"(MZT),":[14],"yet":[15],"its":[16,158],"impact":[17],"on":[18],"spatial":[19],"regulation":[20],"has":[21],"remained":[22],"largely":[23],"unexplored.":[24],"We":[25],"identify":[26],"Cth1":[27,75,104,114,143,156,161],"as":[28,115],"first":[30,126],"maternally":[31],"encoded":[32],"RNA-decay":[33],"factor":[34],"regulated":[35,131],"in":[36,43,85,93,174],"a":[37,94,116,145],"spatiotemporal":[38],"manner":[39],"outside":[40,134],"germline":[42],"zebrafish,":[44],"driven":[45],"by":[46],"conserved":[47],"3\u2032UTR":[48],"cis":[49],"-elements.":[50],"RfxCas13d-mediated":[51],"depletion":[52,102],"of":[53,78,98,103,119,155],"maternal":[54,86,121,148],"cth1":[55],"revealed":[56],"early":[57,139,167],"developmental":[58],"defects":[59],"that":[60,129,150],"could":[61],"not":[62],"be":[63],"assessed":[64],"with":[65],"SpyCas9":[66],"mutants":[67],"due":[68],"to":[69,88,138,177],"infertility":[70],"from":[71],"impaired":[72],"gametogenesis.":[73],"Mechanistically,":[74],"acts":[76],"independently":[77],"zygotic":[79],"genome":[80],"activation,":[81],"recognizing":[82],"AU-rich":[83,172],"motifs":[84,100],"3\u2032UTRs":[87,176],"promote":[89],"deadenylation":[90],"and":[91,108,123,166],"spatio-temporal":[95,159],"manner;":[96],"deletion":[97],"these":[99],"or":[101],"stabilizes":[105],"both":[106],"reporter":[107],"endogenous":[109],"transcripts.":[110],"These":[111],"findings":[112],"establish":[113],"key":[117],"component":[118],"program":[122],"provide":[124],"direct":[127],"evidence":[128],"spatio-temporally":[130],"decay,":[133],"germline,":[136],"contributes":[137],"vertebrate":[140],"development.":[141,169],"Highlights":[142],"highly":[146],"deposited":[147],"undergoes":[151],"rapid":[152],"3\u2019UTR":[154],"drives":[157],"dynamics.":[160],"gametogenesis":[165],"embryonic":[168],"CTH1":[170],"recognizes":[171],"elements":[173],"target":[175],"trigger":[178],"decay.":[179]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-08-25T00:00:00"}