{"id":"https://openalex.org/W7204114911","doi":"https://doi.org/10.3390/cancers18172745","title":"Patient Selection for Partial Breast Irradiation in the Era of Sentinel Lymph Node Biopsy Omission: A Narrative Review","display_name":"Patient Selection for Partial Breast Irradiation in the Era of Sentinel Lymph Node Biopsy Omission: A Narrative Review","publication_year":2026,"publication_date":"2026-08-24","ids":{"openalex":"https://openalex.org/W7204114911","doi":"https://doi.org/10.3390/cancers18172745","pmid":"https://pubmed.ncbi.nlm.nih.gov/42738268","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13564926"},"language":"en","primary_location":{"id":"doi:10.3390/cancers18172745","doi":"https://doi.org/10.3390/cancers18172745","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers18172745","pdf_url":null,"source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/cancers18172745","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015300055","display_name":"Efstratios Karagiannis","orcid":"https://orcid.org/0000-0001-5905-5872","observed_orcids":["https://orcid.org/0000-0001-5905-5872"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Efstratios Karagiannis","raw_affiliation_strings":["Department of Radiation Oncology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5142100120","display_name":"Roger von Moos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Roger von Moos","raw_affiliation_strings":["Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086529264","display_name":"Alessia M. Lardi","orcid":"https://orcid.org/0000-0002-1642-8605","observed_orcids":["https://orcid.org/0000-0002-1642-8605"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alessia Lardi","raw_affiliation_strings":["Department of Plastic Surgery, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plastic Surgery, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147983965","display_name":"Silke-Gerda Brockmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Silke-Gerda Brockmann","raw_affiliation_strings":["Department of Radiation Oncology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074459832","display_name":"Peter Martin Fehr","orcid":"https://orcid.org/0000-0001-8168-8457","observed_orcids":["https://orcid.org/0000-0001-8168-8457"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Peter Martin Fehr","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044116406","display_name":"Tobias Freyholdt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Tobias Freyholdt","raw_affiliation_strings":["Department of Radiology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035838287","display_name":"Ursula Hasler-Strub","orcid":"https://orcid.org/0000-0002-2500-5882","observed_orcids":["https://orcid.org/0000-0002-2500-5882"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Ursula Hasler-Strub","raw_affiliation_strings":["Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147994448","display_name":"Daniel Krause","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Daniel Krause","raw_affiliation_strings":["Department of Pathology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036793394","display_name":"Martina Maranta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Martina Maranta","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013542754","display_name":"Riccardo Lorenzini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Riccardo Lorenzini","raw_affiliation_strings":["Department of Plastic Surgery, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plastic Surgery, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147996813","display_name":"Mirija W\u00fcster","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Mirija W\u00fcster","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067227133","display_name":"Barbara-Christina Padberg Sgier","orcid":"https://orcid.org/0000-0003-3454-0681","observed_orcids":["https://orcid.org/0000-0003-3454-0681"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Barbara-Christina Padberg Sgier","raw_affiliation_strings":["Department of Pathology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110630559","display_name":"Sophie Reinhart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sophie Reinhart","raw_affiliation_strings":["Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067379593","display_name":"Alexander Rieke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alexander Rieke","raw_affiliation_strings":["Department of Radiology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057817742","display_name":"Stefan Kneifel","orcid":"https://orcid.org/0000-0003-2220-2968","observed_orcids":["https://orcid.org/0000-0003-2220-2968"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Stefan Kneifel","raw_affiliation_strings":["Department of Nuclear Medicine, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088124378","display_name":"Johann Sch\u00f6nhofer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Johann Sch\u00f6nhofer","raw_affiliation_strings":["Department of Radiology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031289598","display_name":"Michael Schwitter","orcid":"https://orcid.org/0009-0006-7594-0904","observed_orcids":["https://orcid.org/0009-0006-7594-0904"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Schwitter","raw_affiliation_strings":["Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":"https://orcid.org/0009-0006-7594-0904","affiliations":[{"raw_affiliation_string":"Department of Medical Oncology/Hematology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073791585","display_name":"Robert Wenger","orcid":"https://orcid.org/0000-0002-2898-8917","observed_orcids":["https://orcid.org/0000-0002-2898-8917"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Robert Wenger","raw_affiliation_strings":["Department of Plastic Surgery, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-2898-8917","affiliations":[{"raw_affiliation_string":"Department of Plastic Surgery, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004449061","display_name":"Marc Wermke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Marc Wermke","raw_affiliation_strings":["Department of Nuclear Medicine, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5104240228","display_name":"Winfried Arnold","orcid":"https://orcid.org/0009-0004-6168-2794","observed_orcids":["https://orcid.org/0009-0004-6168-2794"]},"institutions":[{"id":"https://openalex.org/I4210148531","display_name":"Kantonsspital Graub\u00fcnden","ror":"https://ror.org/04wpn1218","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210148531"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Winfried Arnold","raw_affiliation_strings":["Department of Radiation Oncology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland"],"raw_orcid":"https://orcid.org/0009-0004-6168-2794","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Kantonsspital Graub\u00fcnden, 7000 Chur, Switzerland","institution_ids":["https://openalex.org/I4210148531"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5015300055"],"corresponding_institution_ids":["https://openalex.org/I4210148531"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"17","first_page":"2745","last_page":"2745"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/partial-breast-irradiation","display_name":"partial breast irradiation","score":1.0},{"id":"https://openalex.org/keywords/early-breast-cancer","display_name":"early breast cancer","score":0.9769999980926514},{"id":"https://openalex.org/keywords/patient-selection","display_name":"patient selection","score":0.7630000114440918},{"id":"https://openalex.org/keywords/occult-nodal-disease","display_name":"occult nodal disease","score":0.8479999899864197},{"id":"https://openalex.org/keywords/whole-breast-irradiation","display_name":"whole breast irradiation","score":0.7269999980926514},{"id":"https://openalex.org/keywords/risk-assessment","display_name":"risk assessment","score":0.5320000052452087},{"id":"https://openalex.org/keywords/molecular-profiling","display_name":"molecular profiling","score":0.7559999823570251},{"id":"https://openalex.org/keywords/predictive-model","display_name":"prediction model","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9107999801635742},{"id":"https://openalex.org/C2780212769","wikidata":"https://www.wikidata.org/wiki/Q776290","display_name":"Sentinel lymph node","level":4,"score":0.7360000014305115},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.6442000269889832},{"id":"https://openalex.org/C3020000205","wikidata":"https://www.wikidata.org/wiki/Q2412849","display_name":"Narrative review","level":2,"score":0.6107000112533569},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5078999996185303},{"id":"https://openalex.org/C179671157","wikidata":"https://www.wikidata.org/wiki/Q2422612","display_name":"Sentinel node","level":4,"score":0.5044999718666077},{"id":"https://openalex.org/C520017518","wikidata":"https://www.wikidata.org/wiki/Q178934","display_name":"Occult","level":3,"score":0.4887999892234802},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4404999911785126},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.43160000443458557},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.42559999227523804},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.41200000047683716},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4032999873161316},{"id":"https://openalex.org/C2776608951","wikidata":"https://www.wikidata.org/wiki/Q499","display_name":"Axilla","level":4,"score":0.4027999937534332},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.3822999894618988},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3725000023841858},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.34150001406669617},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.3357999920845032},{"id":"https://openalex.org/C2777649267","wikidata":"https://www.wikidata.org/wiki/Q340695","display_name":"Axillary lymph nodes","level":4,"score":0.33059999346733093},{"id":"https://openalex.org/C2908949552","wikidata":"https://www.wikidata.org/wiki/Q1809305","display_name":"Axillary Lymph Node Dissection","level":5,"score":0.2913999855518341},{"id":"https://openalex.org/C140608501","wikidata":"https://www.wikidata.org/wiki/Q7318358","display_name":"Review article","level":2,"score":0.2903999984264374},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.29019999504089355},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2856000065803528},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2806999981403351},{"id":"https://openalex.org/C2777517664","wikidata":"https://www.wikidata.org/wiki/Q4959785","display_name":"Breast biopsy","level":5,"score":0.27799999713897705},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.2605000138282776}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/cancers18172745","doi":"https://doi.org/10.3390/cancers18172745","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers18172745","pdf_url":null,"source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13564926","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13564926/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13564926/pdf/cancers-18-02745.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers (Basel)","raw_type":"Text"},{"id":"pmid:42738268","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42738268","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/cancers18172745","doi":"https://doi.org/10.3390/cancers18172745","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers18172745","pdf_url":null,"source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204114911.pdf","grobid_xml":"https://content.openalex.org/works/W7204114911.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1482938994","https://openalex.org/W2027748666","https://openalex.org/W2031493694","https://openalex.org/W2067420088","https://openalex.org/W2079594432","https://openalex.org/W2096499183","https://openalex.org/W2122428334","https://openalex.org/W2131719808","https://openalex.org/W2156065000","https://openalex.org/W2528580611","https://openalex.org/W2980765487","https://openalex.org/W2993667428","https://openalex.org/W3081515379","https://openalex.org/W3186242874","https://openalex.org/W4205292601","https://openalex.org/W4234066875","https://openalex.org/W4310071647","https://openalex.org/W4313546351","https://openalex.org/W4319262230","https://openalex.org/W4320892490","https://openalex.org/W4385855809","https://openalex.org/W4386910136","https://openalex.org/W4388706033","https://openalex.org/W4389452822","https://openalex.org/W4396952252","https://openalex.org/W4405320092","https://openalex.org/W4406436762","https://openalex.org/W4409318033","https://openalex.org/W4409502905","https://openalex.org/W4411197793","https://openalex.org/W4411399578","https://openalex.org/W4412074303","https://openalex.org/W7117161550","https://openalex.org/W7161118802","https://openalex.org/W7169870870"],"related_works":["https://openalex.org/W7167366447","https://openalex.org/W4411627062","https://openalex.org/W7203964795","https://openalex.org/W7221081927","https://openalex.org/W7170135833","https://openalex.org/W7205007128","https://openalex.org/W4413881477","https://openalex.org/W4409502905","https://openalex.org/W7165777135","https://openalex.org/W7154237892"],"abstract_inverted_index":{"Partial":[0],"breast":[1,23],"irradiation":[2,146],"(PBI)":[3],"and":[4,113,130,149,160,232],"omission":[5,181,210],"of":[6,18,123,141,153,178,182,193,202,220],"sentinel":[7,60],"lymph":[8,61],"node":[9,62],"biopsy":[10,63],"(SLNB)":[11,64],"are":[12,76],"major":[13],"advances":[14],"in":[15,69],"the":[16,47,121,128,139,150,213,228],"de-escalation":[17,223],"locoregional":[19],"treatment":[20],"for":[21,82,137,163,217,237],"early-stage":[22],"cancer.":[24],"These":[25],"strategies":[26],"have":[27,57],"evolved":[28],"independently":[29],"under":[30],"different":[31],"clinical":[32,131,239],"assumptions.":[33],"The":[34],"randomized":[35],"trials":[36,56],"establishing":[37],"PBI":[38,83,110,179,203],"incorporated":[39],"pathological":[40,86,104],"axillary":[41],"staging":[42,106],"into":[43],"patient":[44,135],"selection,":[45],"although":[46],"permitted":[48],"nodal":[49,87,105,165,185],"burden":[50],"varied":[51],"among":[52],"studies,":[53],"whereas":[54],"contemporary":[55,208],"demonstrated":[58],"that":[59],"can":[65],"be":[66,188],"safely":[67],"omitted":[68],"carefully":[70],"selected":[71],"patients.":[72],"Consequently,":[73],"radiation":[74],"oncologists":[75],"increasingly":[77],"encountering":[78],"otherwise":[79,206],"suitable":[80],"candidates":[81],"who":[84],"lack":[85],"information":[88,186],"because":[89],"SLNB":[90,124],"has":[91],"been":[92],"omitted,":[93],"creating":[94],"an":[95,199],"important":[96],"evidence":[97,143,172,230],"gap.":[98],"This":[99,225],"narrative":[100],"review":[101,226],"examines":[102],"how":[103],"became":[107],"embedded":[108],"within":[109],"eligibility":[111],"criteria":[112,211],"whether":[114],"this":[115,221],"long-standing":[116],"requirement":[117],"remains":[118],"justified":[119],"following":[120,180],"introduction":[122],"omission.":[125],"We":[126],"discuss":[127],"biological":[129],"rationale":[132],"underlying":[133],"current":[134],"selection":[136],"PBI,":[138,148],"limitations":[140],"extrapolating":[142],"from":[144],"whole-breast":[145],"to":[147,167],"potential":[151],"contribution":[152],"modern":[154],"imaging,":[155],"tumor":[156],"biology,":[157],"molecular":[158],"profiling,":[159],"prediction":[161],"models":[162],"occult":[164],"disease":[166],"individualized":[168],"risk":[169,195],"assessment.":[170],"Current":[171],"does":[173],"not":[174],"justify":[175],"routine":[176],"implementation":[177],"SLNB.":[183],"Pathological":[184],"may":[187],"considered":[189],"as":[190],"one":[191],"component":[192],"integrated":[194],"assessment":[196],"rather":[197],"than":[198],"isolated":[200],"determinant":[201],"eligibility.":[204],"Patients":[205],"meeting":[207],"radiotherapy":[209],"represent":[212],"most":[214],"appropriate":[215],"population":[216],"prospective":[218],"evaluation":[219],"combined":[222],"strategy.":[224],"defines":[227],"resulting":[229],"gap":[231],"proposes":[233],"a":[234],"conceptual":[235],"framework":[236],"future":[238],"investigation.":[240]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-08-25T00:00:00"}