{"id":"https://openalex.org/W7204010227","doi":"https://doi.org/10.1016/j.phymed.2026.158742","title":"Zaoshi Huatan Xiefei formula improved severe pneumonia by regulating MAPK/NF-\u03baB/VCAM1 signaling pathway mediated leukocyte transendothelial migration","display_name":"Zaoshi Huatan Xiefei formula improved severe pneumonia by regulating MAPK/NF-\u03baB/VCAM1 signaling pathway mediated leukocyte transendothelial migration","publication_year":2026,"publication_date":"2026-08-22","ids":{"openalex":"https://openalex.org/W7204010227","doi":"https://doi.org/10.1016/j.phymed.2026.158742","pmid":"https://pubmed.ncbi.nlm.nih.gov/42667898"},"language":"en","primary_location":{"id":"doi:10.1016/j.phymed.2026.158742","doi":"https://doi.org/10.1016/j.phymed.2026.158742","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.phymed.2026.158742","pdf_url":null,"source":{"id":"https://openalex.org/S180051340","display_name":"Phytomedicine","issn_l":"0944-7113","issn":["0944-7113","1618-095X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomedicine","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7204010227"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036585764","display_name":"Baixi Shan","orcid":"https://orcid.org/0000-0001-9743-5681","observed_orcids":["https://orcid.org/0000-0001-9743-5681"]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baixi Shan","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147874875","display_name":"Shuaijun Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuaijun Zhao","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101861535","display_name":"Zhijing Zhang","orcid":"https://orcid.org/0009-0003-1420-6405","observed_orcids":["https://orcid.org/0009-0003-1420-6405"]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhijing Zhang","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123760337","display_name":"Haiyang Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haiyang Cao","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021613560","display_name":"Yuhang Jiang","orcid":"https://orcid.org/0000-0002-6396-2309","observed_orcids":["https://orcid.org/0000-0002-6396-2309"]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuhang Jiang","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129618308","display_name":"Yan Du","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Du","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123629953","display_name":"Qin Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin Zhang","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129613542","display_name":"Peng Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Zhao","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100631200","display_name":"Jiansheng Li","orcid":"https://orcid.org/0000-0002-6485-2371","observed_orcids":["https://orcid.org/0000-0002-6485-2371"]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]},{"id":"https://openalex.org/I4210144860","display_name":"First Affiliated Hospital of Henan University of Traditional Chinese Medicine","ror":"https://ror.org/059c9vn90","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144860"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiansheng Li","raw_affiliation_strings":["Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: li_js8@163.com"],"raw_orcid":"https://orcid.org/0000-0002-6485-2371","affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450046, Henan Province, China; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China; The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: li_js8@163.com","institution_ids":["https://openalex.org/I160354188","https://openalex.org/I4210144860"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100631200"],"corresponding_institution_ids":["https://openalex.org/I160354188","https://openalex.org/I4210144860"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":null,"fwci":7.9553,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.92318947,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"161","issue":null,"first_page":"158742","last_page":"158742"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.5884000062942505,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.5884000062942505,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.18029999732971191,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13444","display_name":"Traditional Chinese Medicine Clinical Research","score":0.15760000050067902,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/severe-pneumonia","display_name":"severe pneumonia","score":0.9409999847412109},{"id":"https://openalex.org/keywords/vcam-1","display_name":"VCAM-1","score":0.984000027179718},{"id":"https://openalex.org/keywords/leukocyte-transendothelial-migration","display_name":"leukocyte transendothelial migration","score":1.0},{"id":"https://openalex.org/keywords/pulmonary-inflammation","display_name":"lung inflammation","score":0.7670000195503235},{"id":"https://openalex.org/keywords/bioactive-ingredients","display_name":"bioactive ingredients","score":0.6909999847412109},{"id":"https://openalex.org/keywords/erk1-2","display_name":"ERK1/2","score":0.9179999828338623},{"id":"https://openalex.org/keywords/jnk","display_name":"JNK","score":0.9929999709129333},{"id":"https://openalex.org/keywords/p38-mapk","display_name":"p38 MAPK","score":0.9139999747276306},{"id":"https://openalex.org/keywords/traditional-chinese-medicine","display_name":"traditional Chinese medicine","score":0.7889999747276306}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5641999840736389},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5638999938964844},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.5514000058174133},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4731999933719635},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.46459999680519104},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.42660000920295715},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.415800005197525},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.382099986076355},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.3499000072479248},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3474000096321106},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3328000009059906},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.3303000032901764},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32739999890327454},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3203999996185303},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2971999943256378},{"id":"https://openalex.org/C1621761","wikidata":"https://www.wikidata.org/wiki/Q7997549","display_name":"Whole blood","level":2,"score":0.28349998593330383},{"id":"https://openalex.org/C2777730290","wikidata":"https://www.wikidata.org/wiki/Q411114","display_name":"NF-\u03baB","level":3,"score":0.2621000111103058},{"id":"https://openalex.org/C188947578","wikidata":"https://www.wikidata.org/wiki/Q200253","display_name":"Traditional Chinese medicine","level":3,"score":0.2565999925136566}],"mesh":[{"descriptor_ui":"D000091484","descriptor_name":"Network Pharmacology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019010","descriptor_name":"Vascular Cell Adhesion Molecule-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020935","descriptor_name":"MAP Kinase Signaling System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.phymed.2026.158742","doi":"https://doi.org/10.1016/j.phymed.2026.158742","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.phymed.2026.158742","pdf_url":null,"source":{"id":"https://openalex.org/S180051340","display_name":"Phytomedicine","issn_l":"0944-7113","issn":["0944-7113","1618-095X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomedicine","raw_type":"journal-article"},{"id":"pmid:42667898","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42667898","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomedicine : international journal of phytotherapy and phytopharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3102582471","display_name":null,"funder_award_id":"GZC20252562","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G7552701574","display_name":null,"funder_award_id":"82505342","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W2093194698","https://openalex.org/W2120862613","https://openalex.org/W2337589896","https://openalex.org/W2605400647","https://openalex.org/W2610088530","https://openalex.org/W2897555853","https://openalex.org/W3160294760","https://openalex.org/W3189488004","https://openalex.org/W3194632782","https://openalex.org/W3216674570","https://openalex.org/W4220805694","https://openalex.org/W4229007786","https://openalex.org/W4292133355","https://openalex.org/W4306953126","https://openalex.org/W4327680992","https://openalex.org/W4361212691","https://openalex.org/W4362584941","https://openalex.org/W4376619150","https://openalex.org/W4385782717","https://openalex.org/W4386913518","https://openalex.org/W4387564101","https://openalex.org/W4388799086","https://openalex.org/W4392343318","https://openalex.org/W4392361475","https://openalex.org/W4392882903","https://openalex.org/W4393988891","https://openalex.org/W4396559539","https://openalex.org/W4400076903","https://openalex.org/W4402580992","https://openalex.org/W4406034780","https://openalex.org/W4406916859","https://openalex.org/W4406940498","https://openalex.org/W4406978580","https://openalex.org/W4407217923","https://openalex.org/W4407853914","https://openalex.org/W4408596693"],"related_works":["https://openalex.org/W4400562296","https://openalex.org/W4283207049","https://openalex.org/W4407382086","https://openalex.org/W4400927746","https://openalex.org/W7118133332","https://openalex.org/W4213341922","https://openalex.org/W4386046235","https://openalex.org/W7166880950","https://openalex.org/W4393069225","https://openalex.org/W7159835719"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-08-23T00:00:00"}