{"id":"https://openalex.org/W7204005795","doi":"https://doi.org/10.1093/geroni/igag091","title":"Reducing oral frailty improves functional independence in older Brazilians: a causal inference study of disability-free survival using longitudinal modified treatment policies","display_name":"Reducing oral frailty improves functional independence in older Brazilians: a causal inference study of disability-free survival using longitudinal modified treatment policies","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7204005795","doi":"https://doi.org/10.1093/geroni/igag091","pmid":"https://pubmed.ncbi.nlm.nih.gov/42802737","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13616044"},"language":"en","primary_location":{"id":"doi:10.1093/geroni/igag091","doi":"https://doi.org/10.1093/geroni/igag091","is_oa":true,"landing_page_url":"https://doi.org/10.1093/geroni/igag091","pdf_url":null,"source":{"id":"https://openalex.org/S2735557189","display_name":"Innovation in Aging","issn_l":"2399-5300","issn":["2399-5300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovation in Aging","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/geroni/igag091","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048004926","display_name":"John Rong Hao Tay","orcid":"https://orcid.org/0000-0003-3042-3103","observed_orcids":["https://orcid.org/0000-0003-3042-3103"]},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]},{"id":"https://openalex.org/I4210144008","display_name":"National Dental Centre of Singapore","ror":"https://ror.org/03w6pea42","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4210144008"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"John Rong Hao Tay","raw_affiliation_strings":["Health Services Research & Population Health Programme, Duke-NUS Medical School , Singapore,","National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,"],"raw_orcid":"https://orcid.org/0000-0003-3042-3103","affiliations":[{"raw_affiliation_string":"Health Services Research & Population Health Programme, Duke-NUS Medical School , Singapore,","institution_ids":["https://openalex.org/I4210126319"]},{"raw_affiliation_string":"National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,","institution_ids":["https://openalex.org/I4210144008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147820884","display_name":"Huihua Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097409","display_name":"SingHealth Duke-NUS Academic Medical Centre","ror":"https://ror.org/00xcwps97","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I157582758","https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210097409","https://openalex.org/I4210126319"]},{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]},{"id":"https://openalex.org/I4210144008","display_name":"National Dental Centre of Singapore","ror":"https://ror.org/03w6pea42","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4210144008"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Huihua Li","raw_affiliation_strings":["National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,","Oral Health Academic Clinical Programme, Duke-NUS Medical School , Singapore,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,","institution_ids":["https://openalex.org/I4210144008"]},{"raw_affiliation_string":"Oral Health Academic Clinical Programme, Duke-NUS Medical School , Singapore,","institution_ids":["https://openalex.org/I4210097409","https://openalex.org/I4210126319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112833768","display_name":"Karen Glazer de Anselmo Peres","orcid":"https://orcid.org/0000-0002-1730-2123","observed_orcids":["https://orcid.org/0000-0002-1730-2123"]},"institutions":[{"id":"https://openalex.org/I4210144008","display_name":"National Dental Centre of Singapore","ror":"https://ror.org/03w6pea42","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4210144008"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Karen G Peres","raw_affiliation_strings":["National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,","institution_ids":["https://openalex.org/I4210144008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044371088","display_name":"Rahul Malhotra","orcid":"https://orcid.org/0000-0002-9978-4276","observed_orcids":["https://orcid.org/0000-0002-9978-4276","https://orcid.org/0000-0002-9046-5105"]},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Rahul Malhotra","raw_affiliation_strings":["Centre for Ageing Research & Education, Duke-NUS Medical School , Singapore,","Health Services Research & Population Health Programme, Duke-NUS Medical School , Singapore,"],"raw_orcid":"https://orcid.org/0000-0002-9978-4276","affiliations":[{"raw_affiliation_string":"Centre for Ageing Research & Education, Duke-NUS Medical School , Singapore,","institution_ids":["https://openalex.org/I4210126319"]},{"raw_affiliation_string":"Health Services Research & Population Health Programme, Duke-NUS Medical School , Singapore,","institution_ids":["https://openalex.org/I4210126319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023382914","display_name":"Anna Quialheiro","orcid":"https://orcid.org/0000-0002-4168-6585","observed_orcids":["https://orcid.org/0000-0002-4168-6585"]},"institutions":[{"id":"https://openalex.org/I4210096930","display_name":"Cooperativa de Ensino Superior Polit\u00e9cnico e Universit\u00e1rio","ror":"https://ror.org/00w7bj245","country_code":"PT","type":"education","lineage":["https://openalex.org/I4210096930"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Anna Quialheiro","raw_affiliation_strings":["IA&Sa\u00fade - The Artificial Intelligence and Health Research Unit, Polytechnic University of Health, CESPU, Vila Nova de Famalic\u00e3o, Portugal , Lisbon,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IA&Sa\u00fade - The Artificial Intelligence and Health Research Unit, Polytechnic University of Health, CESPU, Vila Nova de Famalic\u00e3o, Portugal , Lisbon,","institution_ids":["https://openalex.org/I4210096930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017055614","display_name":"Eleonora d\u2019Orsi","orcid":"https://orcid.org/0000-0003-2027-1089","observed_orcids":["https://orcid.org/0000-0003-2027-1089"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Eleonora D\u2019Orsi","raw_affiliation_strings":["Department of Public Health, Federal University of Santa Catarina , Florian\u00f3polis,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health, Federal University of Santa Catarina , Florian\u00f3polis,","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047663812","display_name":"Marco Aur\u00e9lio Peres","orcid":"https://orcid.org/0000-0002-8329-2808","observed_orcids":["https://orcid.org/0000-0002-8329-2808"]},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]},{"id":"https://openalex.org/I4210144008","display_name":"National Dental Centre of Singapore","ror":"https://ror.org/03w6pea42","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4210144008"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Marco A Peres","raw_affiliation_strings":["Health Services Research & Population Health Programme, Duke-NUS Medical School , Singapore,","National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,"],"raw_orcid":"https://orcid.org/0000-0002-8329-2808","affiliations":[{"raw_affiliation_string":"Health Services Research & Population Health Programme, Duke-NUS Medical School , Singapore,","institution_ids":["https://openalex.org/I4210126319"]},{"raw_affiliation_string":"National Dental Research Institute Singapore, National Dental Centre Singapore , Singapore,","institution_ids":["https://openalex.org/I4210144008"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5047663812"],"corresponding_institution_ids":["https://openalex.org/I4210126319","https://openalex.org/I4210144008"],"apc_list":{"value":3977,"currency":"USD","value_usd":3977},"apc_paid":{"value":3977,"currency":"USD","value_usd":3977},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.55753567,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"10","first_page":"igag091","last_page":"igag091"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.05660000070929527,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12811","display_name":"Aging, Health, and Disability","score":0.026599999517202377,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-frailty","display_name":"oral frailty","score":1.0},{"id":"https://openalex.org/keywords/functional-independence","display_name":"functional independence","score":0.9240000247955322},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.7739999890327454},{"id":"https://openalex.org/keywords/disability-free-survival","display_name":"disability-free survival","score":0.8460000157356262},{"id":"https://openalex.org/keywords/activities-of-daily-living","display_name":"activities of daily living","score":0.9559999704360962},{"id":"https://openalex.org/keywords/edentulism","display_name":"edentulism","score":0.8889999985694885},{"id":"https://openalex.org/keywords/mastication","display_name":"mastication","score":0.9929999709129333},{"id":"https://openalex.org/keywords/oral-health","display_name":"oral health","score":0.9409999847412109},{"id":"https://openalex.org/keywords/healthy-aging","display_name":"healthy aging","score":0.9639999866485596},{"id":"https://openalex.org/keywords/causal-effect-estimation","display_name":"causal effect estimation","score":0.4359999895095825},{"id":"https://openalex.org/keywords/targeted-maximum-likelihood-estimation","display_name":"targeted maximum likelihood estimation","score":0.6620000004768372},{"id":"https://openalex.org/keywords/community-dwelling-elderly","display_name":"community-dwelling older adults","score":0.6620000004768372},{"id":"https://openalex.org/keywords/brazil","display_name":"Brazil","score":0.3479999899864197}],"concepts":[{"id":"https://openalex.org/C2777576356","wikidata":"https://www.wikidata.org/wiki/Q3579096","display_name":"Edentulism","level":3,"score":0.7900999784469604},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.7702999711036682},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6848999857902527},{"id":"https://openalex.org/C158600405","wikidata":"https://www.wikidata.org/wiki/Q5054566","display_name":"Causal inference","level":2,"score":0.6470000147819519},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.560699999332428},{"id":"https://openalex.org/C26831200","wikidata":"https://www.wikidata.org/wiki/Q16963953","display_name":"Marginal structural model","level":3,"score":0.5246999859809875},{"id":"https://openalex.org/C35651441","wikidata":"https://www.wikidata.org/wiki/Q625303","display_name":"Independence (probability theory)","level":2,"score":0.445499986410141},{"id":"https://openalex.org/C2778401919","wikidata":"https://www.wikidata.org/wiki/Q7824270","display_name":"Tooth loss","level":3,"score":0.4431999921798706},{"id":"https://openalex.org/C193206974","wikidata":"https://www.wikidata.org/wiki/Q6785539","display_name":"Masticatory force","level":2,"score":0.4424999952316284},{"id":"https://openalex.org/C2992672162","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Oral health","level":2,"score":0.43970000743865967},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.42250001430511475},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4106999933719635},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.4056999981403351},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4025000035762787},{"id":"https://openalex.org/C2780176501","wikidata":"https://www.wikidata.org/wiki/Q5690755","display_name":"Health and Retirement Study","level":2,"score":0.37869998812675476},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.37860000133514404},{"id":"https://openalex.org/C3019887659","wikidata":"https://www.wikidata.org/wiki/Q191089","display_name":"Older people","level":2,"score":0.36469998955726624},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.35280001163482666},{"id":"https://openalex.org/C79544238","wikidata":"https://www.wikidata.org/wiki/Q423243","display_name":"Activities of daily living","level":2,"score":0.3264000117778778},{"id":"https://openalex.org/C54183767","wikidata":"https://www.wikidata.org/wiki/Q10384","display_name":"Geriatrics","level":2,"score":0.31189998984336853},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.29829999804496765},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.29440000653266907},{"id":"https://openalex.org/C64357122","wikidata":"https://www.wikidata.org/wiki/Q1149766","display_name":"Causality (physics)","level":2,"score":0.26170000433921814},{"id":"https://openalex.org/C2778175527","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Successful aging","level":2,"score":0.25589999556541443},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.2554999887943268},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2513999938964844}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1093/geroni/igag091","doi":"https://doi.org/10.1093/geroni/igag091","is_oa":true,"landing_page_url":"https://doi.org/10.1093/geroni/igag091","pdf_url":null,"source":{"id":"https://openalex.org/S2735557189","display_name":"Innovation in Aging","issn_l":"2399-5300","issn":["2399-5300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovation in Aging","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13616044","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13616044/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13616044/pdf/igag091.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innov Aging","raw_type":"Text"},{"id":"pmid:42802737","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42802737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovation in aging","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05791927v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05791927","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Innovation in Aging, 2026, 10 (10), &#x27E8;10.1093/geroni/igag091&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/geroni/igag091","doi":"https://doi.org/10.1093/geroni/igag091","is_oa":true,"landing_page_url":"https://doi.org/10.1093/geroni/igag091","pdf_url":null,"source":{"id":"https://openalex.org/S2735557189","display_name":"Innovation in Aging","issn_l":"2399-5300","issn":["2399-5300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovation in Aging","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4625855201","display_name":null,"funder_award_id":"MOH-001416-01","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"},{"id":"https://openalex.org/G7032377350","display_name":null,"funder_award_id":"RTF24jan-0007","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320316262","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098"},{"id":"https://openalex.org/F4320334737","display_name":"National Medical Research Council","ror":"https://ror.org/04x3cxs03"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7204005795.pdf","grobid_xml":"https://content.openalex.org/works/W7204005795.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1567177238","https://openalex.org/W1900956557","https://openalex.org/W1973250499","https://openalex.org/W2021543135","https://openalex.org/W2076621484","https://openalex.org/W2095403845","https://openalex.org/W2115098571","https://openalex.org/W2142477324","https://openalex.org/W2172151487","https://openalex.org/W2607611808","https://openalex.org/W2735301415","https://openalex.org/W2769430780","https://openalex.org/W2770145172","https://openalex.org/W2776685588","https://openalex.org/W2949036829","https://openalex.org/W4210587582","https://openalex.org/W4306292933","https://openalex.org/W4313339857","https://openalex.org/W4366742534","https://openalex.org/W4384498072","https://openalex.org/W4386119140","https://openalex.org/W4386895637","https://openalex.org/W4395688002","https://openalex.org/W4401393608","https://openalex.org/W4403237597","https://openalex.org/W4403509496","https://openalex.org/W4409558944","https://openalex.org/W4413451329","https://openalex.org/W4414166831","https://openalex.org/W4414367200","https://openalex.org/W4414608123","https://openalex.org/W4414850450","https://openalex.org/W4416764650","https://openalex.org/W4417290786","https://openalex.org/W7130517948","https://openalex.org/W7138835470","https://openalex.org/W7138890473","https://openalex.org/W7140233409","https://openalex.org/W7160704039","https://openalex.org/W7161151546","https://openalex.org/W7161607393","https://openalex.org/W7165197956","https://openalex.org/W7204551720"],"related_works":["https://openalex.org/W7155094007","https://openalex.org/W4414850450","https://openalex.org/W4404074247","https://openalex.org/W7133560087","https://openalex.org/W7147333862","https://openalex.org/W2769430780","https://openalex.org/W3175509815","https://openalex.org/W7129265212","https://openalex.org/W4403509496","https://openalex.org/W4401356969"],"abstract_inverted_index":{"Background":[0],"and":[1,11,45,61,114,143,163,200,215,219,224,236],"Objectives:":[2],"Poor":[3],"oral":[4,20,36,135,155,222],"health":[5,21,136,242],"is":[6,243],"associated":[7],"with":[8,23,129,189,234],"functional":[9,24,229],"decline":[10],"mortality":[12],"in":[13,35,47,57,78,154],"older":[14,55,77,181,232],"adults,":[15,233],"yet":[16],"causal":[17],"evidence":[18],"linking":[19],"improvement":[22,137],"independence":[25,230],"remains":[26],"limited.":[27],"We":[28],"simulated":[29,133],"the":[30,39,65,108,158,195],"effects":[31,238],"of":[32,42,50,70,111,160,197,247],"hypothetical":[33],"reductions":[34],"frailty":[37,91,156,223],"on":[38,210,239],"cumulative":[40,109],"probability":[41,110,159,196],"being":[43,112,161,198],"alive":[44,113,162,199],"independent":[46,165,180,202],"basic":[48],"activities":[49],"daily":[51],"living":[52],"(ADLs)":[53],"among":[54,231],"adults":[56,72,182],"Brazil.":[58],"Research":[59],"Design":[60],"Methods:":[62],"Data":[63],"from":[64,82],"EpiFloripa":[66],"Aging":[67],"Cohort":[68],"Study":[69],"community-dwelling":[71],"aged":[73],"60":[74],"years":[75],"or":[76],"Florian\u00f3polis,":[79],"Brazil,":[80],"followed":[81],"2009":[83],"to":[84,175],"2023,":[85],"were":[86,213],"analyzed":[87],"(1702":[88],"participants).":[89],"Oral":[90,241],"was":[92,107],"measured":[93],"at":[94],"waves":[95],"1-3":[96],"using":[97,120],"a":[98,121,244],"seven-item":[99],"composite":[100],"score":[101],"(range":[102],"0-7).":[103],"The":[104],"primary":[105],"outcome":[106],"ADL-independent":[115],"through":[116],"wave":[117],"5,":[118],"estimated":[119],"discrete-time":[122],"survival":[123,211],"model.":[124],"Longitudinal":[125],"modified":[126],"treatment":[127],"policies":[128],"targeted":[130],"maximum-likelihood":[131],"estimation":[132],"nine":[134],"scenarios,":[138],"accounting":[139],"for":[140],"time-varying":[141],"confounding":[142],"censoring.":[144],"Results:":[145],"336":[146],"deaths":[147],"occurred":[148],"during":[149],"follow-up.":[150],"A":[151],"stepwise":[152],"reduction":[153],"increased":[157],"ADL":[164,201],"by":[166],"73%":[167],"(probability":[168,203],"ratio":[169,204],"1.73,":[170],"95%":[171,206],"CI":[172,207],"1.48-2.02),":[173],"corresponding":[174],"15":[176],"829":[177],"additional":[178],"functionally":[179],"per":[183],"100":[184],"000":[185],"individuals.":[186],"Preventing":[187],"edentulism":[188],"preserved":[190],"masticatory":[191,226],"function":[192,227],"also":[193],"improved":[194],"1.21,":[205],"1.08-1.36).":[208],"Effects":[209],"alone":[212],"smaller":[214,235],"less":[216],"certain.":[217],"Discussion":[218],"Implications:":[220],"Reducing":[221],"preserving":[225],"increases":[228],"uncertain":[237],"survival.":[240],"modifiable":[245],"determinant":[246],"healthy":[248],"ageing.":[249]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-08-23T00:00:00"}
