{"id":"https://openalex.org/W7203880710","doi":"https://doi.org/10.3389/fnins.2026.1911095","title":"On the reliability of non-hermetically encapsulated ceramic printed circuit boards as bridging elements in neural implants","display_name":"On the reliability of non-hermetically encapsulated ceramic printed circuit boards as bridging elements in neural implants","publication_year":2026,"publication_date":"2026-08-21","ids":{"openalex":"https://openalex.org/W7203880710","doi":"https://doi.org/10.3389/fnins.2026.1911095","pmid":"https://pubmed.ncbi.nlm.nih.gov/42698669","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13541673"},"language":"en","primary_location":{"id":"doi:10.3389/fnins.2026.1911095","doi":"https://doi.org/10.3389/fnins.2026.1911095","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnins.2026.1911095","pdf_url":null,"source":{"id":"https://openalex.org/S115201632","display_name":"Frontiers in Neuroscience","issn_l":"1662-453X","issn":["1662-453X","1662-4548"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3389/fnins.2026.1911095","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5158560944","display_name":"Julien Martens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Julien Martens","raw_affiliation_strings":["BrainLinks-BrainTools Center, IMBIT, University of Freiburg","Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BrainLinks-BrainTools Center, IMBIT, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140299925","display_name":"L. Henneken","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lukas Henneken","raw_affiliation_strings":["BrainLinks-BrainTools Center, IMBIT, University of Freiburg","Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BrainLinks-BrainTools Center, IMBIT, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147733131","display_name":"Alexandra Zehr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexandra Zehr","raw_affiliation_strings":["BrainLinks-BrainTools Center, IMBIT, University of Freiburg","Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BrainLinks-BrainTools Center, IMBIT, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128794889","display_name":"Cemre Cevahir Otyakmazoglu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Cemre Otyakmazoglu","raw_affiliation_strings":["BrainLinks-BrainTools Center, IMBIT, University of Freiburg","Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BrainLinks-BrainTools Center, IMBIT, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057740989","display_name":"Paul \u010cvan\u010dara","orcid":"https://orcid.org/0000-0003-2189-4413","observed_orcids":["https://orcid.org/0000-0003-2189-4413"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Paul \u010cvan\u010dara","raw_affiliation_strings":["BrainLinks-BrainTools Center, IMBIT, University of Freiburg","Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BrainLinks-BrainTools Center, IMBIT, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058067206","display_name":"Thomas Stieglitz","orcid":"https://orcid.org/0000-0002-7349-4254","observed_orcids":["https://orcid.org/0000-0002-7349-4254"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210098324","display_name":"Bernstein Center for Computational Neuroscience Freiburg","ror":"https://ror.org/010p50m34","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210092532","https://openalex.org/I4210098324"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Thomas Stieglitz","raw_affiliation_strings":["Bernstein Center Freiburg, University of Freiburg","BrainLinks-BrainTools Center, IMBIT, University of Freiburg","Freiburg Materials Research Center-FMF, University of Freiburg","Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bernstein Center Freiburg, University of Freiburg","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210098324"]},{"raw_affiliation_string":"BrainLinks-BrainTools Center, IMBIT, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Freiburg Materials Research Center-FMF, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Laboratory for Biomedical Microtechnology, IMTEK, University of Freiburg","institution_ids":["https://openalex.org/I161046081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5058067206","https://openalex.org/A5158560944"],"corresponding_institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210098324"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.50574533,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":null,"first_page":"1911095","last_page":"1911095"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10460","display_name":"Electronic Packaging and Soldering Technologies","score":0.006599999964237213,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11523","display_name":"Nanomaterials and Printing Technologies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neural-implants","display_name":"neural implants","score":0.8980000019073486},{"id":"https://openalex.org/keywords/neural-interfaces","display_name":"neural interfaces","score":0.628000020980835},{"id":"https://openalex.org/keywords/platinum-thin-films","display_name":"platinum thin films","score":0.7160000205039978},{"id":"https://openalex.org/keywords/adhesion-promoters","display_name":"adhesion promoters","score":0.8899999856948853},{"id":"https://openalex.org/keywords/silicon-nitride","display_name":"silicon nitride","score":0.7570000290870667},{"id":"https://openalex.org/keywords/silica","display_name":"silica","score":0.6919999718666077},{"id":"https://openalex.org/keywords/alumina-substrate","display_name":"alumina substrate","score":0.8339999914169312},{"id":"https://openalex.org/keywords/pdms-encapsulation","display_name":"PDMS encapsulation","score":0.9100000262260437},{"id":"https://openalex.org/keywords/tensile-shear-strength","display_name":"lap shear strength","score":0.8519999980926514},{"id":"https://openalex.org/keywords/electrical-insulation","display_name":"electrical insulation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/accelerated-aging","display_name":"accelerated aging","score":0.7360000014305115},{"id":"https://openalex.org/keywords/phosphate-buffered-saline","display_name":"phosphate buffered saline","score":0.8849999904632568},{"id":"https://openalex.org/keywords/pulsed-laser-deposition","display_name":"pulsed laser deposition","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.8374000191688538},{"id":"https://openalex.org/C134132462","wikidata":"https://www.wikidata.org/wiki/Q45621","display_name":"Ceramic","level":2,"score":0.6377999782562256},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.6116999983787537},{"id":"https://openalex.org/C2781448156","wikidata":"https://www.wikidata.org/wiki/Q1570182","display_name":"Coating","level":2,"score":0.515500009059906},{"id":"https://openalex.org/C112950240","wikidata":"https://www.wikidata.org/wiki/Q76005","display_name":"Ultimate tensile strength","level":2,"score":0.48590001463890076},{"id":"https://openalex.org/C7040849","wikidata":"https://www.wikidata.org/wiki/Q899580","display_name":"Dielectric spectroscopy","level":4,"score":0.45410001277923584},{"id":"https://openalex.org/C174348530","wikidata":"https://www.wikidata.org/wiki/Q188635","display_name":"Bridging (networking)","level":2,"score":0.4496000111103058},{"id":"https://openalex.org/C177564732","wikidata":"https://www.wikidata.org/wiki/Q7698333","display_name":"Temperature cycling","level":3,"score":0.40230000019073486},{"id":"https://openalex.org/C2780965675","wikidata":"https://www.wikidata.org/wiki/Q145958","display_name":"Polyimide","level":3,"score":0.3781999945640564},{"id":"https://openalex.org/C69990965","wikidata":"https://www.wikidata.org/wiki/Q65402698","display_name":"Electrical resistivity and conductivity","level":2,"score":0.3578999936580658},{"id":"https://openalex.org/C178405089","wikidata":"https://www.wikidata.org/wiki/Q857201","display_name":"Flexural strength","level":2,"score":0.35040000081062317},{"id":"https://openalex.org/C69544855","wikidata":"https://www.wikidata.org/wiki/Q757625","display_name":"Atomic layer deposition","level":3,"score":0.32109999656677246},{"id":"https://openalex.org/C127893833","wikidata":"https://www.wikidata.org/wiki/Q7492185","display_name":"Shear strength (soil)","level":3,"score":0.31520000100135803},{"id":"https://openalex.org/C2779227376","wikidata":"https://www.wikidata.org/wiki/Q6505497","display_name":"Layer (electronics)","level":2,"score":0.30709999799728394},{"id":"https://openalex.org/C518104683","wikidata":"https://www.wikidata.org/wiki/Q880","display_name":"Platinum","level":3,"score":0.3019999861717224},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.29899999499320984},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.2948000133037567},{"id":"https://openalex.org/C68928338","wikidata":"https://www.wikidata.org/wiki/Q131790","display_name":"Adhesive","level":3,"score":0.29440000653266907},{"id":"https://openalex.org/C118820876","wikidata":"https://www.wikidata.org/wiki/Q4672283","display_name":"Accelerated aging","level":2,"score":0.28870001435279846},{"id":"https://openalex.org/C115974795","wikidata":"https://www.wikidata.org/wiki/Q337701","display_name":"Ceramic capacitor","level":4,"score":0.2750000059604645}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fnins.2026.1911095","doi":"https://doi.org/10.3389/fnins.2026.1911095","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnins.2026.1911095","pdf_url":null,"source":{"id":"https://openalex.org/S115201632","display_name":"Frontiers in Neuroscience","issn_l":"1662-453X","issn":["1662-453X","1662-4548"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroscience","raw_type":"journal-article"},{"id":"pmid:42698669","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42698669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13541673","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13541673/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neurosci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:135ea179a2714950b2fc7c05eea866f1","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/135ea179a2714950b2fc7c05eea866f1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neuroscience, Vol 20 (2026)","raw_type":"article"},{"id":"pmh:oai:freidok.uni-freiburg.de:285958","doi":null,"is_oa":false,"landing_page_url":"https://nbn-resolving.org/urn:nbn:de:bsz:25-freidok-2859583","pdf_url":null,"source":{"id":"https://openalex.org/S4306401057","display_name":"FreiDok plus (Universit\u00e4tsbibliothek Freiburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I161046081","host_organization_name":"University of Freiburg","host_organization_lineage":["https://openalex.org/I161046081"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in neuroscience. - 20 (2026) , 1911095, ISSN: 1662-453X","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fnins.2026.1911095","doi":"https://doi.org/10.3389/fnins.2026.1911095","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnins.2026.1911095","pdf_url":null,"source":{"id":"https://openalex.org/S115201632","display_name":"Frontiers in Neuroscience","issn_l":"1662-453X","issn":["1662-453X","1662-4548"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1966835255","https://openalex.org/W1990283232","https://openalex.org/W2012853348","https://openalex.org/W2016292555","https://openalex.org/W2054968793","https://openalex.org/W2134500330","https://openalex.org/W2898667019","https://openalex.org/W2902344618","https://openalex.org/W2915043420","https://openalex.org/W2972339980","https://openalex.org/W3088713697","https://openalex.org/W3130209080","https://openalex.org/W4388811282","https://openalex.org/W4400727368","https://openalex.org/W4406002718","https://openalex.org/W7151535266","https://openalex.org/W7167796596"],"related_works":["https://openalex.org/W2883203897","https://openalex.org/W2946755393","https://openalex.org/W3033620724","https://openalex.org/W2047162583","https://openalex.org/W2047226238","https://openalex.org/W2134458940","https://openalex.org/W2479948646","https://openalex.org/W4407072857","https://openalex.org/W2061897341","https://openalex.org/W2067692467"],"abstract_inverted_index":{"Introduction":[0],"Robust,":[1],"biocompatible":[2],"ceramic":[3,316],"electrical":[4,67,304],"interconnects":[5,317],"are":[6],"essential":[7],"for":[8,36,138,313,318],"bridging":[9],"the":[10,44,61,203,210,234,278,287,294,297,303],"gap":[11],"between":[12],"macro-scale":[13],"components,":[14],"such":[15],"as":[16],"helically":[17],"wound":[18],"leads":[19],"and":[20,22,47,69,114,134,166,252,266,300,325],"connectors,":[21],"thin-film":[23,51,96,117,150],"polyimide":[24],"electrodes":[25],"in":[26,184,276,306],"neural":[27],"interfaces.":[28],"While":[29],"screen-printed":[30],"thick-film":[31,152],"structures":[32],"have":[33],"been":[34],"utilized":[35],"decades,":[37],"there":[38],"is":[39],"a":[40,156,160,167],"need":[41],"to":[42,59,219,233],"broaden":[43],"design":[45],"space":[46],"improve":[48],"reliability":[49],"through":[50],"techniques.":[52],"This":[53],"study":[54],"evaluates":[55],"various":[56],"surface":[57],"configurations":[58],"identify":[60],"optimal":[62,315],"combination":[63],"of":[64,169,212,289,296,302],"mechanical":[65,216,298],"adhesion,":[66],"insulation,":[68],"functional":[70],"longevity.":[71],"Methods":[72],"All":[73,179],"samples":[74,180,254],"were":[75],"fabricated":[76],"on":[77,263],"96%":[78],"pure":[79],"alumina":[80],"(Al":[81],"2":[82,109,121,158,175,236,248,268],"O":[83,122,176,237,249],"3":[84,123,177,238,250],")":[85],"substrates.":[86,124],"Mechanical":[87],"stability":[88,217,301],"was":[89,127],"evaluated":[90,142],"via":[91],"tensile":[92],"shear":[93,199],"tests,":[94],"comparing":[95],"platinum":[97],"(Pt)":[98],"with":[99,145,154,223],"different":[100],"adhesion":[101,213,230,290],"promoters":[102,214,291],"(Si":[103],"x":[104,162,225,243],"N":[105,163,226,244],"y":[106,164,227,245],",":[107,251],"SiO":[108,157,267],"),":[110],"laser-patterned":[111,253],"Pt":[112,116,265],"thin-films,":[113],"bare":[115,149,220,264],"against":[118],"reference":[119,239],"Al":[120,174,235],"Electrical":[125],"insulation":[126,257,305],"assessed":[128],"by":[129],"performing":[130],"electrochemical":[131],"impedance":[132],"spectroscopy":[133],"DC":[135,270],"resistance":[136,271],"measurements":[137,272],"degradation":[139],"monitoring.":[140],"The":[141,283],"layer":[143,168],"stacks":[144],"PDMS":[146,262],"encapsulation":[147],"included":[148],"Pt,":[151,222],"Pt/Au":[153],"Overglaze,":[155],"layer,":[159,165],"Si":[161,224,242],"pulsed":[170],"laser":[171],"deposition":[172],"(PLD)":[173],".":[178,269],"underwent":[181],"accelerated":[182],"aging":[183,204],"phosphate":[185],"buffered":[186],"saline":[187],"(PBS)":[188],"at":[189],"60\u00b0C":[190],"(acceleration":[191],"factor":[192],"\u223c":[193],"4.92":[194],"vs.":[195],"37\u00b0C).":[196],"Results":[197],"Tensile":[198],"strength":[200],"decreased":[201],"over":[202,259],"period":[205],"across":[206],"all":[207],"groups.":[208],"However,":[209],"integration":[211],"increased":[215],"compared":[218],"sputtered":[221],"coating":[228],"bringing":[229],"levels":[231],"close":[232],"samples.":[240],"Electrically,":[241],"-,":[246],"PLD-Al":[247],"maintained":[255],"higher":[256],"impedances":[258],"time":[260],"than":[261],"indicate":[273],"good":[274],"capabilities":[275],"protecting":[277],"conductors":[279],"from":[280],"degradation.":[281],"Discussion":[282],"findings":[284],"demonstrate":[285],"that":[286],"addition":[288],"enhances":[292],"both":[293],"longevity":[295],"bond":[299],"ion-rich":[307],"environments.":[308],"These":[309],"results":[310],"provide":[311],"guidance":[312],"selecting":[314],"chronic":[319],"peripheral-nerve":[320],"implants,":[321],"balancing":[322],"reliability,":[323],"manufacturability,":[324],"cost.":[326]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-08-22T00:00:00"}