{"id":"https://openalex.org/W7203819892","doi":"https://doi.org/10.1007/s10924-026-03952-x","title":"Immunomodulatory Activity of a Low-molecular-weight \u03b2-glucan Produced by Liquid Fermentation of Chaetomium globosum","display_name":"Immunomodulatory Activity of a Low-molecular-weight \u03b2-glucan Produced by Liquid Fermentation of Chaetomium globosum","publication_year":2026,"publication_date":"2026-08-20","ids":{"openalex":"https://openalex.org/W7203819892","doi":"https://doi.org/10.1007/s10924-026-03952-x"},"language":"en","primary_location":{"id":"doi:10.1007/s10924-026-03952-x","doi":"https://doi.org/10.1007/s10924-026-03952-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10924-026-03952-x","pdf_url":null,"source":{"id":"https://openalex.org/S193665811","display_name":"Journal of Polymers and the Environment","issn_l":"1064-7546","issn":["1064-7546","1064-7564","1566-2543","1572-8900","1572-8919"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Polymers and the Environment","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018162534","display_name":"Zichao Wang","orcid":"https://orcid.org/0000-0001-5375-2669","observed_orcids":["https://orcid.org/0000-0001-5375-2669"]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zichao Wang","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":"https://orcid.org/0000-0001-5375-2669","affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147501615","display_name":"Feifei Qin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feifei Qin","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034125898","display_name":"Yixin Shi","orcid":"https://orcid.org/0000-0001-7267-6796","observed_orcids":["https://orcid.org/0000-0001-7267-6796","https://orcid.org/0009-0008-9444-5292"]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yixin Shi","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085843947","display_name":"Xueyan Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueyan Zhou","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112644306","display_name":"Haozhi Yuan","orcid":"https://orcid.org/0009-0001-7761-5447","observed_orcids":["https://orcid.org/0009-0001-7761-5447"]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haozhi Yuan","raw_affiliation_strings":["School of International Education, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of International Education, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100341313","display_name":"Qi Wang","orcid":"https://orcid.org/0000-0002-6643-8561","observed_orcids":["https://orcid.org/0000-0002-6643-8561"]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qi Wang","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147640845","display_name":"Yahui Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yahui Yang","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147515738","display_name":"Xueqin Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueqin Wang","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147489443","display_name":"Guojun Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guojun Wang","raw_affiliation_strings":["Nanjing Kershine Biotechnology Co., Ltd, Nanjing, 211801, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nanjing Kershine Biotechnology Co., Ltd, Nanjing, 211801, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081664704","display_name":"Yanli Qi","orcid":"https://orcid.org/0000-0002-8664-8355","observed_orcids":["https://orcid.org/0000-0002-8664-8355"]},"institutions":[{"id":"https://openalex.org/I36152291","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55","country_code":"CN","type":"education","lineage":["https://openalex.org/I36152291"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yanli Qi","raw_affiliation_strings":["School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Engineering, Henan Provincial Key Laboratory of Grain Resource Conversion and Utilization, Henan University of Technology, Zhengzhou, 450001, China","institution_ids":["https://openalex.org/I36152291"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113251042","display_name":"Lemei An","orcid":"https://orcid.org/0000-0002-9510-2186","observed_orcids":["https://orcid.org/0000-0002-9510-2186"]},"institutions":[{"id":"https://openalex.org/I38877650","display_name":"Zhengzhou University","ror":"https://ror.org/04ypx8c21","country_code":"CN","type":"education","lineage":["https://openalex.org/I38877650"]},{"id":"https://openalex.org/I4210133534","display_name":"Henan Provincial People's Hospital","ror":"https://ror.org/03f72zw41","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210133534"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lemei An","raw_affiliation_strings":["Department of Rheumatology and Clinical Immunology, Henan Provincial People\u2019s Hospital, People\u2019s Hospital of Zhengzhou University, Zhengzhou, 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Clinical Immunology, Henan Provincial People\u2019s Hospital, People\u2019s Hospital of Zhengzhou University, Zhengzhou, 450003, China","institution_ids":["https://openalex.org/I38877650","https://openalex.org/I4210133534"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5018162534","https://openalex.org/A5081664704","https://openalex.org/A5100341313","https://openalex.org/A5113251042"],"corresponding_institution_ids":["https://openalex.org/I36152291","https://openalex.org/I38877650","https://openalex.org/I4210133534"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.63527842,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"34","issue":"9","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12192","display_name":"Polysaccharides Composition and Applications","score":0.03739999979734421,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chaetomium-globosum","display_name":"Chaetomium globosum","score":0.9700000286102295},{"id":"https://openalex.org/keywords/submerged-fermentation","display_name":"submerged fermentation","score":0.972000002861023},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.9490000009536743},{"id":"https://openalex.org/keywords/raw-264-7-macrophages","display_name":"RAW 264.7 macrophages","score":0.9259999990463257},{"id":"https://openalex.org/keywords/phagocytic-activity","display_name":"phagocytic activity","score":0.8970000147819519},{"id":"https://openalex.org/keywords/nitric-oxide-production","display_name":"nitric oxide production","score":0.8769999742507935},{"id":"https://openalex.org/keywords/cytokine-production","display_name":"cytokine production","score":0.6330000162124634},{"id":"https://openalex.org/keywords/water-soluble-polysaccharides","display_name":"water-soluble polysaccharides","score":0.8349999785423279},{"id":"https://openalex.org/keywords/fungal-polysaccharide-production","display_name":"fungal polysaccharide production","score":0.6370000243186951}],"concepts":[{"id":"https://openalex.org/C2910378060","wikidata":"https://www.wikidata.org/wiki/Q2947551","display_name":"Chaetomium globosum","level":2,"score":0.9787999987602234},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.757099986076355},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5867000222206116},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.5254999995231628},{"id":"https://openalex.org/C2780589914","wikidata":"https://www.wikidata.org/wiki/Q10675206","display_name":"Ingredient","level":2,"score":0.5145000219345093},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4645000100135803},{"id":"https://openalex.org/C155574463","wikidata":"https://www.wikidata.org/wiki/Q170731","display_name":"Solubility","level":2,"score":0.4307999908924103},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3785000145435333},{"id":"https://openalex.org/C2778577587","wikidata":"https://www.wikidata.org/wiki/Q3665729","display_name":"Chaetomium","level":3,"score":0.37070000171661377},{"id":"https://openalex.org/C206139338","wikidata":"https://www.wikidata.org/wiki/Q192355","display_name":"Raw material","level":2,"score":0.2904999852180481},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.2732999920845032},{"id":"https://openalex.org/C73401843","wikidata":"https://www.wikidata.org/wiki/Q845523","display_name":"Industrial fermentation","level":3,"score":0.26910001039505005},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.25519999861717224},{"id":"https://openalex.org/C2778977261","wikidata":"https://www.wikidata.org/wiki/Q11358","display_name":"Carbohydrate","level":2,"score":0.2533000111579895}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s10924-026-03952-x","doi":"https://doi.org/10.1007/s10924-026-03952-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10924-026-03952-x","pdf_url":null,"source":{"id":"https://openalex.org/S193665811","display_name":"Journal of Polymers and the Environment","issn_l":"1064-7546","issn":["1064-7546","1064-7564","1566-2543","1572-8900","1572-8919"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Polymers and the Environment","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":84,"referenced_works":["https://openalex.org/W2163728230","https://openalex.org/W2171140274","https://openalex.org/W2291045772","https://openalex.org/W2469579962","https://openalex.org/W2741559286","https://openalex.org/W2765559893","https://openalex.org/W2903210271","https://openalex.org/W2947471318","https://openalex.org/W2955565397","https://openalex.org/W2962974178","https://openalex.org/W2972704514","https://openalex.org/W2983028324","https://openalex.org/W2985410472","https://openalex.org/W3004869518","https://openalex.org/W3007413348","https://openalex.org/W3021359419","https://openalex.org/W3029506415","https://openalex.org/W3087809068","https://openalex.org/W3089165514","https://openalex.org/W3111015931","https://openalex.org/W3133809146","https://openalex.org/W3211261796","https://openalex.org/W4224034231","https://openalex.org/W4225095214","https://openalex.org/W4229035380","https://openalex.org/W4281935346","https://openalex.org/W4284968058","https://openalex.org/W4298001469","https://openalex.org/W4307217084","https://openalex.org/W4311772360","https://openalex.org/W4312128861","https://openalex.org/W4313414312","https://openalex.org/W4319602226","https://openalex.org/W4323031144","https://openalex.org/W4323304507","https://openalex.org/W4366992980","https://openalex.org/W4378516236","https://openalex.org/W4379375160","https://openalex.org/W4380767708","https://openalex.org/W4385614584","https://openalex.org/W4388458789","https://openalex.org/W4390547904","https://openalex.org/W4390670843","https://openalex.org/W4394823140","https://openalex.org/W4396744026","https://openalex.org/W4400095028","https://openalex.org/W4400390953","https://openalex.org/W4400438933","https://openalex.org/W4403904908","https://openalex.org/W4404026821","https://openalex.org/W4404489908","https://openalex.org/W4406083029","https://openalex.org/W4406282835","https://openalex.org/W4406344207","https://openalex.org/W4406602747","https://openalex.org/W4407411430","https://openalex.org/W4408634291","https://openalex.org/W4408635045","https://openalex.org/W4409068176","https://openalex.org/W4410835897","https://openalex.org/W4410980321","https://openalex.org/W4411089278","https://openalex.org/W4411402745","https://openalex.org/W4411442996","https://openalex.org/W4411491337","https://openalex.org/W4412684582","https://openalex.org/W4413292425","https://openalex.org/W4414068609","https://openalex.org/W4414491558","https://openalex.org/W4414575465","https://openalex.org/W4414714618","https://openalex.org/W4414837152","https://openalex.org/W4415216125","https://openalex.org/W4415254861","https://openalex.org/W4415488530","https://openalex.org/W4416331832","https://openalex.org/W4416674704","https://openalex.org/W4417258464","https://openalex.org/W4417264609","https://openalex.org/W7125939236","https://openalex.org/W7147148019","https://openalex.org/W7153015686","https://openalex.org/W7159866990","https://openalex.org/W7160878395"],"related_works":["https://openalex.org/W2271236092","https://openalex.org/W7167919250","https://openalex.org/W2042212475","https://openalex.org/W2888033982","https://openalex.org/W4220939013","https://openalex.org/W7124701164","https://openalex.org/W2921795255","https://openalex.org/W2028462429","https://openalex.org/W4413385128","https://openalex.org/W2146324977"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-24T07:57:37.273135","created_date":"2026-08-21T00:00:00"}
